Neupane P, Mimura K, Nakajima S, Okayama H, Ito M, Thar Min AK, Saito K, Onozawa H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Kono K. The Expression of Immune Checkpoint Receptors and Ligands in the Colorectal Cancer Tumor Microenvironment. Anticancer Research. 202110; 41(10):4895-4905.
Ueda K, Kumari R, Schwenger E, Wheat JC, Bohorquez O, Narayanagari SR, Taylor SJ, Carvajal LA, Pradhan K, Bartholdy B, Todorova TI, Goto H, Sun D, Chen J, Shan J, Song Y, Montagna C, Xiong S, Lozano G, Pellagatti A, Boultwood J, Verma A, Steidl U. MDMX acts as a pervasive preleukemic-to-acute myeloid leukemia transition mechanism. Cancer Cell. 202104; 39(4):529-547.e7.
Min AKT, Mimura K, Nakajima S, Okayama H, Saito K, Sakamoto W, Fujita S, Endo H, Saito M, Saze Z, Momma T, Ohki S, Kono K. Therapeutic potential of anti-VEGF receptor 2 therapy targeting for M2-tumor-associatedmacrophages in colorectal cancer. Cancer Immunology, Immunotherapy. 202102; 70(2):289-298.
Kase K, Saito M, Nakajima S, Takayanagi D, Saito K, Yamada L, Ashizawa M, Nakano H, Hanayama H,Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Shiraishi K, Kohno T, Kono K. ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation. Carcinogenesis. 202102; 42(1):21-30.
Sano H, Mochizuki K, Kobayashi S, Ohara Y, Takahashi N, Kudo S, Waragai T, Ikeda K, Ohto H, Kikuta A. Effectiveness of T-Cell Replete Haploidentical Hematopoietic Stem Cell Transplantation for Refractory/Relapsed B Cell Acute Lymphoblastic Leukemia in Children and Adolescents. Frontiers in Pediatrics. 202110; 9:743294.
Yamada L, Saito M, Thar Min AK, Saito K, Ashizawa M, Kase K, Nakajima S, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Kono K. Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer. Gastric Cancer. 202101; 24(1):60-71.
Mimura K, Kua LF, Xiao JF, Asuncion BR, Nakayama Y, Syn N, Fazreen Z, Soong R, Kono K, Yong WP. Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models. Gastric Cancer. 202105; 24(3):611-623.
Yokokawa T, Misaka T, Kimishima Y, Wada K, Minakawa K, Sugimoto K, Ishida T, Morishita S, Komatsu N, Ikeda K, Takeishi Y. Crucial role of hematopoietic JAK2 V617F in the development of aortic aneurysms. Haematologica. 202107; 106(7):1910-1922.
Shima E, Go H, Maeda H, Ogasawara K, Imamura T, Sasaki M, Koh Y, Nollet KE, Ikeda K, Ohto H, Hosoya M. Down syndrome with neonatal alloimmune thrombocytopenia due to anti-HLA A31 and B61 antibodies. International Journal of Hematology. 202106; 113(6):945-949.
Yokokawa T, Misaka T, Kimishima Y, Wada K, Minakawa K, Kaneshiro T, Yoshihisa A, Ikeda K, Takeishi Y. Clonal hematopoiesis and JAK2 V617F mutations in patients with cardiovascular disease. JACC: CardioOncology. 202103; 3(1):134-136.
Minakawa K, Yokokawa T, Ueda K, Nakajima O, Misaka T, Kimishima Y, Wada K, Tomita Y, Miura S, Sato Y, Mimura K, Sugimoto K, Nakazato K, Nollet KE, Ogawa K, Ikezoe T, Hashimoto Y, Takeishi Y, Ikeda K. Myeloproliferative neoplasm-driving Calr frameshift promotes the development of pulmonary hypertension in mice. Journal of Hematology & Oncology. 202103; 14(1):52.
Nakajima S, Mimura K, Saito K, Thar Min AK, Endo E, Yamada L, Kase K, Yamauchi N, Matsumoto T, Nakano H, Kanke Y, Okayama H, Saito M, Neupane P, Saze Z, Watanabe Y, Hanayama H, Hayase S, Kaneta A, Momma T, Ohki S, Ohira H, Kono K. Neoadjuvant chemotherapy induces IL-34 signaling and promotes chemoresistance via tumor-associated macrophage polarization in esophageal squamous cell carcinoma. Molecular Cancer Research. 202106; 19(6):1085-1095.
Ueda K, Steidl U. Epigenetic Achilles’ heel of AML. Nature Cancer. 202105; 2(5):481-483.
Kimishima Y, Misaka T, Yokokawa T, Wada K, Ueda K, Sugimoto K, Minakawa K, Nakazato K, Ishida T, Oshima M, Koide S, Shide K, Shimoda K, Iwama A, Ikeda K, Takeishi Y. Clonal hematopoiesis with JAK2V617F promotes pulmonary hypertension with ALK1 upregulation in lung neutrophils. Nature Communications. 202110; 12(1):6177.
Yamauchi N, Kanke Y, Saito K, Okayama H, Yamada S, Nakajima S, Endo E, Kase K, Yamada L, Nakano H, Matsumoto T, Hanayama H, Watanabe Y, Hayase S, Saito M, Saze Z, Mimura K, Momma T, Oki S, Hashimoto Y, Kono K. Stromal expression of cancer-associated fibroblast-related molecules, versican and lumican, is strongly associated with worse relapse-free and overall survival times in patients with esophageal squamous cell carcinoma. Oncology Letters. 202106; 21(6):445.
Takahashi N, Mochizuki K, Sano H, Kobayashi S, Ohara Y, Ikeda K, Ohto H, Kikuta A. Decline of serum albumin precedes severe acute GVHD after haploidentical HSCT. Pediatrics International. 202109; 63(9):1048- 1054.
Nakano H, Saito M, Nakajima S, Saito K, Nakayama Y, Kase K, Yamada L, Kanke Y, Hanayama H, Onozawa H, Okayama H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Goto A, Kono K. PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms. Scientific Reports. 202101; 11(1):1982.
Nakajima S, Mimura K, Matsumoto T, Thar Min AK, Ito M, Nakano H, Neupane P, Kanke Y, Okayama H, Saito M, Momma T, Watanabe Y, Hanayama H, Hayase S, Saze Z, Kono K. The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells. Scientific Reports. 202108; 11(1):16891.
Tamai Y, Ohto H, Takahashi H, Kitazawa J; Pediatric RBC Alloimmunization Consortium. Transfusion-Related Alloimmunization to Red Blood Cell Antigens in Japanese Pediatric Recipients. Transfusion Medicine Reviews. 202101; 35(1):29-36.
Tamai Y, Ohto H, Yasuda H, Takeshita A, Fujii N, Ogo H, Yazawa Y, Hato T, Mitani K, Suzuki K, Yokohama A, Kato Y, Abe M, Kumagawa M, Ueda Y, Nollet KE, Cooling L, Kitazawa J; Pediatric RBC Alloimmunization Consortium. Allo-anti-M: Detection peaks around 2 years of age, but may be attenuated by red blood cell transfusion. Transfusion. 202109; 61(9):2718-2726.
Furumaki H, Takeshita A, Ohto H, Yamada C, Fujihara H, Ishizuka K, Shibata H, Shinba T, Nemoto N, Ino K, Ozawa A, Watanabe H, Kawabata K, Obata Y. A newly devised flow cytometric antibody binding assay helps evaluation of dithiothreitol treatment for the inactivation of CD38 on red blood cells. Vox Sanguinis. 202107; 116(6):725-734.
Tanaka A, Yokohama A, Fujiwara SI, Fujii Y, Kaneko M, Ueda Y, Abe T, Kato Y, Hasegawa Y, Ikeda K, Fujino K, Matsumoto M, Makino S, Kino S, Takeshita A, Muroi K. Transfusion-associated circulatory overload and high blood pressure: A multicentre retrospective study in Japan. Vox Sanguinis. 202108; 116(7):785-792.
Yokokawa T, Misaka T, Kimishima Y, Wada K, Minakawa K, Sugimoto K, Ishida T, Ikeda K, Takeishi Y. Crucial role of JAK2V617F-positive myeloproliferative neoplasm on the development of aortic aneurysm. Cardiovascular and Metabolic Week 2020: 第28 回日本血管生物医学会学術集会; 20210312-13; Web.
Ikeda K, Misaka T, Kimishima Y, Yokokawa T, Minakawa K, Ueda K, Oshima M, Koide S, Shide K, Shimoda K, Nakajima O, Iwama A, Takeishi Y. Hematopoietic cells with MPN driver mutations promote pulmonary hypertension. 第83 回日本血液学会学術集会; 20210923-25; Web.
Minakawa K, Sato Y, Ueda K, Takahashi S, Watanabe M, Ono S, Kawabata K, Ikezoe T, Kikuta A, Ikeda K. Chimerism analysis by novel KMRtype reagent for Japanese allo-HSCT recipients. 第83 回日本血液学会学術集会; 20210923-25; Web.
Ikeda K, Misaka T, Kimishima Y, Yokokawa T, Minakawa K, Ueda K, Iwama A, Takeishi Y. Clonal hematopoiesis (CH) with JAK2-V617F mutation promotes pulmonary hypertension (PH) through ALK1 (Acvrl1). 第80 回日本癌学会学術総会; 20210930-1002; 横浜/Web.
特別講演
池田和彦. 骨髄増殖性腫瘍におけるドライバー変異と心血管系合併症. MPN WEB Seminar; 20211125; Web.
招待講演
池田和彦. 診療におけるJAK2 変異解析検査の意義. Novartis Hematology Web Seminar; 20211216; Web.
