Abstract/References

Three cases of gastrointestinal stromal tumors with metaiodobenzylguanidine (MIBG) accumulation

Honami Kobiyama, Shiro Ishii, Yumi Saito, Natsumi Kawamoto, Shigeyasu Sugawara, Hiroshi Ito

Author information
  • Honami Kobiyama
    Department of Radiology and Nuclear Medicine, Fukushima Medical University
  • Shiro Ishii
    Department of Radiology and Nuclear Medicine, Fukushima Medical University
  • Yumi Saito
    Department of Radiology and Nuclear Medicine, Fukushima Medical University
  • Natsumi Kawamoto
    Department of Radiology and Nuclear Medicine, Fukushima Medical University
  • Shigeyasu Sugawara
    Department of Radiology and Nuclear Medicine, Fukushima Medical University
  • Hiroshi Ito
    Department of Radiology and Nuclear Medicine, Fukushima Medical University

Abstract

Meta-iodobenzylguanidine (MIBG) is an analog of norepinephrine and guanethidine, and MIBG scintigraphy is useful to diagnose tumors of the sympathetic nervous system, such as pheochromocytoma, paraganglioma, and neuroblastoma.　To date, there have been few reports of MIBG accumulation in gastrointestinal stromal tumors (GISTs), so the mechanism and frequency of MIBG accumulation in GISTs are unknown.　Herein, we report and discuss three cases of GIST in which scintigraphy that was performed to exclude pheochromocytoma showed MIBG accumulation.

The content of research paper

References

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Figures

Medical imaging showing various views of abdominal organs with highlighted areas of interest.
Medical imaging results showing various diagnostic techniques, including scans and endoscopic views.
Medical imaging results showing various scans, including CT and ultrasound, highlighting specific areas of interest.
Medical imaging scans showing various views of abdominal organs, highlighting specific areas of interest.
Table summarizing reported cases of GIST with MIBG accumulation, including patient details and symptoms.

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