論文 - 家村 俊一郎
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The transmembrane nucleoporin NDC1 is required for targeting of ALADIN to nuclear pore complexes.
Yamazumi Y, Kamiya A, Nishida A, Nishihara A, Iemura S, Natsume T, Akiyama T.
Biochem. Biophys. Res. Commun. 389 ( 1 ) 100 - 104 2009年11月
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Atg101, a novel mammalian autophagy protein interacting with Atg13.
Hosokawa N, Sasaki T, Iemura S, Natsume T, Hara T, Mizushima N.
Autophagy 5 ( 7 ) 973 - 979 2009年10月
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Gasp, a Grb2-associating protein, is critical for positive selection of thymocytes.
Patrick MS, Oda H, Hayakawa K, Sato Y, Eshima K, Kirikae T, Iemura S, Shirai M, Abe T, Natsume T, Sasazuki T, Suzuki H.
Proc. Natl. Acad. Sci. U S A. 106 ( 38 ) 16345 - 16350 2009年9月
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Novel in vitro protein fragment complementation assay applicable to high-throughput screening in a 1536-well format.
Hashimoto J, Watanabe T, Seki T, Karasawa S, Izumikawa M, Seki T, Iemura S, Natsume T, Nomura N, Goshima N, Miyawaki A, Takagi M, Shin-Ya K.
J. Biomol. Screen. 14 ( 8 ) 970 - 979 2009年9月
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Mitochondrial phosphoglycerate mutase 5 uses alternate catalytic activity as a protein serine/threonine phosphatase to activate ASK1.
Takeda K, Komuro Y, Hayakawa T, Oguchi H, Ishida Y, Murakami S, Noguchi T, Kinoshita H, Sekine Y, Iemura S, Natsume T, Ichijo H.
Proc. Natl. Acad. Sci. U S A. 106 ( 30 ) 12301 - 12305 2009年7月
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Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperones.
Kaneko T, Hamazaki J, Iemura S, Sasaki K, Furuyama K, Natsume T, Tanaka K, Murata S.
Cell 137 ( 5 ) 914 - 925 2009年5月
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Promotion of neurite extension by protrudin requires its interaction with vesicle-associated membrane protein-associated protein.
Saita S, Shirane M, Natume T, Iemura S, Nakayama KI.
J. Biol. Chem. 284 ( 20 ) 13766 - 13777 2009年5月
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Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.
Kiefer H, Mizutani A, Iemura S, Natsume T, Ando H, Kuroda Y, Mikoshiba K.
J. Biol. Chem. 284 ( 16 ) 10694 - 10705 2009年4月
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Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
Hosokawa N, Hara T, Kaizuka T, Kishi C, Takamura A, Miura Y, Iemura S, Natsume T, Takehana K, Yamada N, Guan JL, Oshiro N, Mizushima N.
Mol. Biol. Cell 20 ( 7 ) 1981 - 1991 2009年4月
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Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration.
Sagara M, Kawasaki Y, Iemura SI, Natsume T, Takai Y, Akiyama T.
Oncogene 28 ( 10 ) 1357 - 1365 2009年3月
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Ankyrin repeat domain 28 (ANKRD28), a novel binding partner of DOCK180, promotes cell migration by regulating focal adhesion formation.
Tachibana M, Kiyokawa E, Hara S, Iemura S, Natsume T, Manabe T, Matsuda M.
Exp. Cell Res. 315 ( 5 ) 863 - 876 2009年3月
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CHD8 suppresses p53-mediated apoptosis through histone H1 recruitment during early embryogenesis.
Nishiyama M, Oshikawa K, Tsukada Y, Nakagawa T, Iemura S, Natsume T, Fan Y, Kikuchi A, Skoultchi AI, Nakayama KI.
Nat. Cell Biol. 11 ( 2 ) 172 - 182 2009年2月
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CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression.
Tomita T, Kido T, Kurotani R, Iemura S, Sterneck E, Natsume T, Vinson C, Kimura S.
J. Biol. Chem. 283 ( 37 ) 25617 - 25627 2008年9月
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The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport.
Hara S, Kiyokawa E, Iemura S, Natsume T, Wassmer T, Cullen PJ, Hiai H, Matsuda M.
Mol. Biol. Cell 19 ( 9 ) 3823 - 3835 2008年9月
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A parallel affinity purification method for selective isolation of polyubiquitinated proteins.
Ota K, Kito K, Iemura S, Natsume T, Ito T.
Proteomics 8 ( 15 ) 3004 - 3007 2008年8月
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FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
Hara T, Takamura A, Kishi C, Iemura S, Natsume T, Guan JL, Mizushima N.
J. Cell Biol. 181 ( 3 ) 497 - 510 2008年5月
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タンパク質のネットワーク解析から創薬へ（超高感度質量分析システムをどのように実現したか）
家村俊一郎, 夏目 徹
Synthesiology 1 ( 2 ) 123 - 129 2008年4月（ ISSN:1882-6229 ）
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Mutations causing DOK7 congenital myasthenia ablate functional motifs in Dok-7.
Hamuro J, Higuchi O, Okada K, Ueno M, Iemura S, Natsume T, Spearman H, Beeson D, Yamanashi Y.
J. Biol. Chem. 283 ( 9 ) 5518 - 5524 2008年2月
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Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.
Komatsu M, Waguri S, Koike M, Sou YS, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K.
Cell 131 ( 6 ) 1149 - 1163 2007年12月
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Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms.
Saijou E, Itoh T, Kim KW, Iemura S, Natsume T, Miyajima A.
J. Biol. Chem. 282 ( 44 ) 32327 - 32337 2007年11月