論文 - 家村 俊一郎
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TBL2 Associates With ATF4 mRNA Via Its WD40 Domain and Regulates Its Translation During ER Stress.
Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.
J. Cell. Biochem. 117 ( 2 ) 500 - 509 2015年12月
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The subcellular localization and activity of cortactin is regulated by acetylation and interaction with Keap1.
Ito A, Shimazu T, Maeda S, Shah AA, Tsunoda T, Iemura S, Natsume T, Suzuki T, Motohashi H, Yamamoto M, Yoshida M.
Sci. Signal. 8 2015年11月
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CACUL1/CAC1 Regulates the Antioxidant Response by Stabilizing Nrf2.
Kigoshi Y, Fukuda T, Endo T, Hayasaka N, Iemura S, Natsume T, Tsuruta F, Chiba T.
Sci Rep. 5 2015年8月
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The endoplasmic reticulum-localized protein TBL2 interacts with the 60S ribosomal subunit.
Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.
Biochem. Biophys. Res. Commun. 462 ( 4 ) 383 - 388 2015年6月
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Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.
ukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, Duan C, Saeki Y, Tanaka K, Iemura S, Natsume T, Chida K, Nakatsu Y, Kamata H, Asano T, Takahashi S.
Nat Commun. 6 2015年4月
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TBL2 is a novel PERK-binding protein that modulates stress-signaling and cell survival during endoplasmic reticulum stress.
Tsukumo Y, Tsukahara S, Furuno A, Iemura S, Natsume T, Tomida A.
PLoS One. 9 ( 11 ) 2014年11月
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ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.
Adachi S, Homoto M, Tanaka R, Hioki Y, Murakami H, Suga H, Matsumoto M, Nakayama KI, Hatta T, Iemura S, Natsume T.
Nucleic Acids Res. 42 ( 15 ) 10037 - 10049 2014年8月
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Structure-activity relationship study, target identification, and pharmacological characterization of a small molecular IL-12/23 inhibitor, APY0201.
Hayakawa N, Noguchi M, Takeshita S, Eviryanti A, Seki Y, Nishio H, Yokoyama R, Noguchi M, Shuto M, Shima Y, Kuribayashi K, Kageyama S, Eda H, Suzuki M, Hatta T, Iemura S, Natsume T, Tanabe I, Nakagawa R, Shiozaki M, Sakurai K, Shoji M, Andou A, Yamamoto T.
Bioorg Med Chem. 22 ( 11 ) 3021 - 3029 2014年6月
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IQGAP1 protein regulates nuclear localization of β-catenin via importin-β5 protein in Wnt signaling.
Goto T, Sato A, Adachi S, Iemura S, Natsume T, Shibuya H.
J Biol Chem. 288 ( 51 ) 36351 - 36360 2013年12月
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Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes.
Hoshi T, Tezuka T, Yokoyama K, Iemura S, Natsume T, Yamanashi Y.
FEBS Lett. 587 ( 23 ) 3749 - 3754 2013年11月
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Dynamic regulation of ero1α and peroxiredoxin 4 localization in the secretory pathway.
Kakihana T, Araki K, Vavassori S, Iemura S, Cortini M, Fagioli C, Natsume T, Sitia R, Nagata K.
J Biol Chem. 288 ( 41 ) 29586 - 29594 2013年10月
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Araki K., Iemura S., Kamiya Y., Ron D., Kato K., Natsume T., Nagata K.
Journal of Cell Biology 202 ( 6 ) 861 - 874 2013年9月（ ISSN:00219525 ）
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Ero1-α and PDIs constitute a hierarchical electron transfer network of endoplasmic reticulum oxidoreductases.
Araki K, Iemura S, Kamiya Y, Ron D, Kato K, Natsume T, Nagata K.
J Cell Biol. 202 ( 6 ) 861 - 874 2013年9月
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The casein kinase 2-nrf1 axis controls the clearance of ubiquitinated proteins by regulating proteasome gene expression.
Tsuchiya Y, Taniguchi H, Ito Y, Morita T, Karim MR, Ohtake N, Fukagai K, Ito T, Okamuro S, Iemura S, Natsume T, Nishida E, Kobayashi A.
Mol Cell Biol. 33 ( 17 ) 3461 - 3472 2013年9月
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PLEIAD/SIMC1/C5orf25, a novel autolysis regulator for a skeletal-muscle-specific calpain, CAPN3, scaffolds a CAPN3 substrate, CTBP1.
Ono Y, Iemura S, Novak SM, Doi N, Kitamura F, Natsume T, Gregorio CC, Sorimachi H.
J Mol Biol. 425 ( 16 ) 2955 - 2972 2013年8月
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Ono Y., Iemura S., Novak S., Doi N., Kitamura F., Natsume T., Gregorio C., Sorimachi H.
Journal of Molecular Biology 425 ( 16 ) 2955 - 2972 2013年8月（ ISSN:00222836 ）
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IQGAP1 Functions as a Modulator of Dishevelled Nuclear Localization in Wnt Signaling.
Goto T, Sato A, Shimizu M, Adachi S, Satoh K, Iemura S, Natsume T, Shibuya H
PLoS One 8 ( 4 ) 2013年4月
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VCP Is an integral component of a novel feedback mechanism that controls intracellular localization of catalase and H2O2 Levels.
Murakami K, Ichinohe Y, Koike M, Sasaoka N, Iemura S, Natsume T, Kakizuka A
PLoS One 8 ( 2 ) 2013年2月
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RPA Assists HSF1 Access to Nucleosomal DNA by Recruiting Histone Chaperone FACT.
Fujimoto M, Takaki E, Takii R, Tan K, Prakasam R, Hayashida N, Iemura S, Natsume T, Nakai A.
Mol Cell. 48 ( 2 ) 182 - 194 2012年10月
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The Kelch Repeat Protein KLHDC10 Regulates Oxidative Stress-Induced ASK1 Activation by Suppressing PP5.
Sekine Y, Hatanaka R, Watanabe T, Sono N, Iemura SI, Natsume T, Kuranaga E, Miura M, Takeda K, Ichijo H.
Mol Cell. 2012年10月