研究者詳細 - 家村　俊一郎

論文 - 家村　俊一郎

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Cleaved PGAM5 dephosphorylates nuclear serine/arginine-rich proteinsduring mitophagy.

Baba T, Tanimura S, Yamaguchi A, Horikawa K, Yokozeki M, Hachiya S, Iemura SI, Natsume T, Matsuda N, Takeda K

Biochimica et biophysica acta. Molecular cell research 119045 2021年4月（ ISSN:0167-4889 ）

NUDT21 Links Mitochondrial IPS-1 to RLR-Containing Stress Granules and Activates Host Antiviral Defense.

Aoyama-Ishiwatari S, Okazaki T, Iemura SI, Natsume T, Okada Y, Gotoh Y

Journal of immunology (Baltimore, Md. : 1950) 206 ( 1 ) 154 - 163 2021年1月（ ISSN:0022-1767 ）

Identification of U11snRNA as an endogenous agonist of TLR7-mediated immune pathogenesis.

Negishi H, Endo N, Nakajima Y, Nishiyama T, Tabunoki Y, Nishio J, Koshiba R, Matsuda A, Matsuki K, Okamura T, Negishi-Koga T, Ichinohe T, Takemura S, Ishiwata H, Iemura SI, Natsume T, Abe T, Kiyonari H, Doi T, Hangai S, Yanai H, Fujio K, Yamamoto K, Taniguchi T

Proceedings of the National Academy of Sciences of the United States of America 116 ( 47 ) 23653 - 23661 2019年11月（ ISSN:0027-8424 ）

FAM48A mediates compensatory autophagy induced by proteasome impairment.

Arata Y, Watanabe A, Motosugi R, Iemura SI, Natsume T, Mukai K, Taguchi T, Hirayama S, Hamazaki J, Murata S

Genes to cells : devoted to molecular & cellular mechanisms 2019年6月（ ISSN:1356-9597 ）

Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.

Hatta T, Iemura SI, Ohishi T, Nakayama H, Seimiya H, Yasuda T, Iizuka K, Fukuda M, Takeda J, Natsume T, Horikawa Y

Scientific reports 8 ( 1 ) 16756 2018年11月

MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs.

Okamoto K, Ohishi T, Kuroiwa M, Iemura SI, Natsume T, Seimiya H

Oncotarget 9 ( 88 ) 35844 - 35855 2018年11月

Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma.

Kim Y, Shiba-Ishii A, Nakagawa T, Iemura SI, Natsume T, Nakano N, Matsuoka R, Sakashita S, Lee S, Kawaguchi A, Sato Y, Noguchi M

Oncogene 37 ( 40 ) 5387 - 5402 2018年10月（ ISSN:0950-9232 ）

β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.

Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K

Biochimica et biophysica acta. General subjects 1862 ( 10 ) 2271 - 2280 2018年10月（ ISSN:0304-4165 ）

Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase.

Yoneyama Y, Inamitsu T, Chida K, Iemura SI, Natsume T, Maeda T, Hakuno F, Takahashi SI

iScience 5 1 - 18 2018年7月

Nuclear export of ubiquitinated proteins via the UBIN-POST system.

Hirayama S, Sugihara M, Morito D, Iemura SI, Natsume T, Murata S, Nagata K

Proceedings of the National Academy of Sciences of the United States of America 115 ( 18 ) E4199 - E4208 2018年5月（ ISSN:0027-8424 ）

Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells.

Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura SI, Natsume T, Miyamura N, Nishina H, Nakayama J, Semba K, Tomita T, Murata S, Arai H, Taguchi T

Nature communications 8 ( 1 ) 1246 2017年11月

Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation.

Fujimori T, Suno R, Iemura SI, Natsume T, Wada I, Hosokawa N

Genes to cells : devoted to molecular & cellular mechanisms 22 ( 8 ) 684 - 698 2017年8月（ ISSN:1356-9597 ）

Tankyrase-binding protein TNKS1BP1 regulates actin cytoskeleton rearrangement and cancer cell invasion

Ohishi T., Yoshida H., Katori M., Migita T., Muramatsu Y., Miyake M., Ishikawa Y., Saiura A., Iemura S., Natsume T., Seimiya H.

Cancer Research 77 ( 9 ) 2328 - 2338 2017年5月（ ISSN:00085472 ）

USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.

Fukushima T, Yoshihara H, Furuta H, Hakuno F, Iemura SI, Natsume T, Nakatsu Y, Kamata H, Asano T, Komada M, Takahashi SI

Biochemical and biophysical research communications 484 ( 3 ) 522 - 528 2017年3月（ ISSN:0006-291X ）

TMED10 Protein Interferes with Transforming Growth Factor (TGF)-β Signaling by Disrupting TGF-β Receptor Complex Formation.

Nakano N, Tsuchiya Y, Kako K, Umezaki K, Sano K, Ikeno S, Otsuka E, Shigeta M, Nakagawa A, Sakata N, Itoh F, Nakano Y, Iemura SI, van Dinther M, Natsume T, Ten Dijke P, Itoh S

The Journal of biological chemistry 292 ( 10 ) 4099 - 4112 2017年3月（ ISSN:0021-9258 ）

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.

Kotani Y, Morito D, Sakata K, Ainuki S, Sugihara M, Hatta T, Iemura SI, Takashima S, Natsume T, Nagata K

Scientific reports 7 44293 2017年3月

Ubiquitylation of Ku80 by RNF126 Promotes Completion of Nonhomologous End Joining-Mediated DNA Repair.

Ishida N, Nakagawa T, Iemura SI, Yasui A, Shima H, Katoh Y, Nagasawa Y, Natsume T, Igarashi K, Nakayama K

Molecular and cellular biology 37 ( 4 ) 2017年2月（ ISSN:0270-7306 ）

WDR26 is a new partner of Axin1 in the canonical Wnt signaling pathway.

Goto T, Matsuzawa J, Iemura S, Natsume T, Shibuya H.

FEBS Letter 590 ( 9 ) 1291 - 1303 2016年5月

Distinct types of protease systems are involved in homeostasis regulation of mitochondrial morphology via balanced fusion and fission.

Saita S, Ishihara T, Maeda M, Iemura S, Natsume T, Mihara K, Ishihara N.

Genes to Cells 21 ( 5 ) 408 - 424 2016年3月

Chaperone complex BAG2-HSC70 regulates localization of Caenorhabditis elegans leucine-rich repeat kinase LRK-1 to the Golgi.

Fukuzono T, Pastuhov SI, Fukushima O, Li C, Hattori A, Iemura S, Natsume T, Shibuya H, Hanafusa H, Matsumoto K, Hisamoto N.

Genes to Cells 21 ( 4 ) 311 - 324 2016年2月

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論文 - 家村 俊一郎

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論文 - 家村　俊一郎