Abstract/References

Effect of rehabilitation in patients undergoing hematopoietic stem cell transplantation

Takahiro Takekiyo, Shinichiro Morishita

Author information
  • Takahiro Takekiyo
    Department of Rehabilitation, Imamura General Hospital
  • Shinichiro Morishita
    Department of Physical Therapy, School of Health Science, Fukushima Medical University

Abstract

Patients undergoing hematopoietic stem cell transplantation (HSCT) tend to experience decline in physical function, mental function, and quality of life (QOL) after HSCT due to low activity caused by adverse reactions to chemotherapy used in pre-transplantation treatment and post-transplant complications. Rehabilitation for HSCT patients is effective in preventing decline in physical function, reducing fatigue, and improving QOL. A combination of aerobic exercise and strength training is recommended for exercise therapy. Risk management is also important in the implementation of exercise therapy, and the exercise intensity should be determined according to the presence of anemia, low platelet counts, or post-transplant complications. On the other hand, post-transplant complications can decrease the patient's motivation and daily activity level. A multidisciplinary approach, which includes physicians and nurses, is important to achieve early discharge from the hospital and as quick a return to society as possible.

The content of research paper

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Figures

Flowchart illustrating the stages of rehabilitation: Pre-Rehabilitation, Inpatient Rehabilitation, and Outpatient Rehabilitation.
Rehabilitation program phases chart outlining pre-rehabilitation, inpatient, and outpatient stages with goals and assessments.
Flowchart illustrating the timeline and procedures for HSCT, including assessments and rehabilitation phases.
Flowchart illustrating factors leading to decreased physical function, including regimen-related toxicity and associated symptoms.
A diagram illustrating various healthcare professionals surrounding a central "Patient Family" label, highlighting their roles in patient care.
Table summarizing physical therapy assessment parameters, including strength, exercise tolerance, balance, body composition, and quality of life measures.
Table summarizing various physical therapy interventions, including study details, type, frequency, time, and intensity.
Table outlining recommended physical exercises and corresponding platelet values for patients with thrombocytopenia.

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