Abstract/References

Ovarian strumal carcinoid: a case report

Masaru Kanasugi, Hiroshi Nishiyama, Minoru Sanpei, Shigeyuki Asano, Tsuyoshi Honda

Abstract

Background:Carcinoid tumors of the ovary are rare tumors, histopathologically classified as monodermal teratomas and somatic-type tumors arising from dermoid cysts. Their malignancy varies from borderline to malignant. Carcinoid tumors can occur in young and elderly women, and are sometimes seen in mature teratoma, struma ovarii, or mucinous cystadenoma as a nodule or tumor. Strumal carcinoid and mucinous carcinoid present as special types of carcinoid tumors of the ovary.

Case report:This report describes a 56-year-old woman who presented with a large pelvic mass on abdominal ultrasonography during a medical examination. The diameter of the pelvic tumor was approximately 11 cm and was suspected to be ovarian cancer. The values of CA125 and CEA were above their reference intervals on preoperative examination. Abdominal total hysterectomy and bilateral salpingo-oophorectomy were performed. Intraoperative frozen-section histopathology suggested a diagnosis of mucinous adenocarcinoma; therefore, partial omentectomy and pelvic lymphadenectomy were also performed. Permanent-section histopathology led to a final diagnosis of strumal carcinoid of the ovary, stage IA (FIGO 2014). Six years post-operation, the patient had no sign of recurrence.

The content of research paper

References

1. WHO Classification of Tumours Editorial Board. WHO Classification of Tumours · 5^th Edition Female Genital Tumours, 132-135, 2020.
2. 2. MO Toyama T, Katayama Y, Watanabe H, et al. Functioning ovarian carcinoids induce severe constipation. Cancer, 70:513-518, 1992.
3. WHO Classification of Tumours Editorial Board. WHO Classification of Tumours · 5^th Edition Female Genital Tumours, 134-135, 2020.
4. Scully RE. Resent progress in ovarian cancer. Hum Pathol, 1(1):73-98, 1970.
5. Wu L, Wang Z, Dai S, et al. Primary strumal carcinoid tumor of the ovary:a case report and literature review. Int. J Clin Exp Pathol, 9:2409-2413, 2016.
6. Lenicek T, Tomas D, Soljacic-Vranes H, et al. Strumal carcinoid of the ovary:report of two cases. Acta Clin Croat, 51:649-635, 2012. PMid:23540174
7. 7. Davis KP, Hartmann LK, Keeny GL, Shapiro H:Primary ovarian carcinoid tumors. Gynecol Oncol, 61:259-265, 1996.
8. Sharma R, Biswas B, Puri Wahal S, Sharma N, Kaushal N. Primary ovarian carcinoid in mature cystic teratoma:A rare entity. Clinical Cancer Investigation Journal, 3:80-82, 2014.
9. 9. Robboy SJ, Scully RE. Strumal carcinoid of the ovary-an analysis of 50 cases of a distinctive tumor composed thyroid-tissue and carcinoid. Cancer, 46:2019-2034, 1980.
10. Ashton MA. Strumal carcinoid of the ovary associated with hyperinsulinemic hypoglycemia and cutaneous melanosis. Hystopathology, 27:463-467, 1995.
11. 11. Takatori E, Shoji T, Miura J, et al. Case of Peptide-YY-producing stromal carcinoid of the ovary:a case report and review. J Obstet Gynecol Res, 38:1266-1270, 2012.

Figures