Abstract/References
Four cases of pseudomyxoma peritonei with ovarian tumors at our hospital
Riho Yazawa, Hiroyuki Yazawa, Kaoru Fukuda, Miki Ohara, Fumihiko Osuka
Author information
- Riho Yazawa
Department of Obstetrics and Gynecology, Fukushima Red Cross Hospital - Hiroyuki Yazawa
Department of Obstetrics and Gynecology, Fukushima Red Cross Hospital - Kaoru Fukuda
Department of Obstetrics and Gynecology, Fukushima Red Cross Hospital - Miki Ohara
Department of Obstetrics and Gynecology, Fukushima Red Cross Hospital - Fumihiko Osuka
Department of Surgery, Fukushima Red Cross Hospital
Abstract
We describe four cases of pseudomyxoma peritonei (PMP) that were diagnosed and treated at our hospital.
Case 1: A 26-year-old woman with a large multicystic ovarian tumor and massive ascites was diagnosed with PMP originating from a borderline mucinous ovarian tumor. She underwent fertility-preserving staging laparotomy and was treated with three courses of intraperitoneal chemotherapy. There has been no recurrence in the 15 years since her first operation. Case 2: A 72-year-old woman with a giant ovarian tumor and massive ascites was diagnosed with PMP originating from low-grade appendiceal mucinous neoplasm (LAMN). After laparotomy, the patient was managed conservatively because she did not want aggressive treatment. She has remained asymptomatic with a small amount of ascites for 3 years. Case 3: A 82-year-old woman with ovarian tumors, massive ascites, and suspected PMP underwent emergency laparotomy due to appendiceal perforation and pan-peritonitis. She was diagnosed with PMP originating from LAMN. She has remained asymptomatic with a small amount of ascites for 2 years. Case 4: A 42-year-old woman with multicystic ovarian tumors and massive ascites underwent laparotomy. She was diagnosed with PMP originating from LAMN. Since multidisciplinary treatment was indicated and desired, the patient was referred to a specialized facility where cytoreductive surgery and hyperthermic intraperitoneal chemotherapy was performed. The patient has done well since the treatment.
Although most cases of PMP originate from mucinous tumors of the appendix, female patients with PMP often present with ovarian tumors and are commonly referred to gynecology clinics. It is therefore important for gynecologists to be familiar with PMP and to be able to diagnose it accurately and select the most suitable management including multidisciplinary treatments.
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