Abstract/References

Peak IgG antibody titers against SARS-CoV-2 spike protein following immunization with the Pfizer/BioNTech BNT162b2 vaccine

Yurie Kobashi, Yuzo Shimazu, Takeshi Kawamura, Yoshitaka Nishikawa, Fumiya Omata, Yudai Kaneko, Tatsuhiko Kodama, Masaharu Tsubokura

Abstract

This study investigated the immune response and outcome of BNT162b2 vaccination among 12 staff at a hospital in Fukushima, Japan. Blood samples were collected from participants before their first vaccination, with subsequent sampling performed during the participants’ work days for six weeks thereafter. Antibody titers peaked 6-13 days after the second vaccination (days 27-34 after the first), followed by a steady decrease. Six males had significantly lower peak antibody titers than six females (p= 0.016 witht-test); the older six (median age 53 years) had lower antibody titers than the younger six (median age 35 years) but without statistical significance (pvalue=0.24 witht-test).

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References

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