Abstract/References
Secular changes in bone mineral density of adult Japanese women from 1995 to 2013
Hiroaki Watanabe, Yasuko Minagawa, Ichiro Suzuki, Kaori Kitamura, Yumi Watanabe, Keiko Kabasawa, Kseniia Platonova, Aya Hinata, Kazutoshi Nakamura, Kazutoshi Nakamura
Author information
- Hiroaki Watanabe
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences
Department of Clinical Engineering and Medical Technology, Niigata University of Health and Welfare - Yasuko Minagawa
Shibata Comprehensive Health Care Service Center - Ichiro Suzuki
Shibata Comprehensive Health Care Service Center - Kaori Kitamura
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences - Yumi Watanabe
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences - Keiko Kabasawa
Department of Health Promotion Medicine, Niigata University Graduate School of Medical and Dental Sciences - Kseniia Platonova
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences - Aya Hinata
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences - Kazutoshi Nakamura
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences - Kazutoshi Nakamura
Department of Preventive Medicine, Niigata University Graduate School of Medical and Dental Sciences
Abstract
Introduction: Secular changes in hip fracture incidence have been reported in the last few decades in Japan, but whether long-term bone mineral density (BMD) is also changing is unclear. This study aimed to determine whether BMD of Japanese women has changed over time.
Methods: Subjects were 10,649 adult women who underwent BMD measurement in a health check-up population in Niigata, Japan, between 1995 and 2013. BMD of the distal, non-dominant forearm was measured by dual-energy X-ray absorptiometry. Demographic information and BMI were also obtained. Secular trends were determined by linear regression analysis.
Results: BMD of subjects in their 40’s decreased significantly in the age-adjusted model (P for trend=0.0162), but not in the age- and BMI-adjusted model (P for trend=0.2171). BMD of subjects in their 50’s decreased marginally in the age-adjusted model (P for trend=0.0535), but not in the age- and BMI-adjusted model (P for trend=0.6601). BMDs of subjects in their 30’s and 60’s did not significantly change, while BMIs of subjects in their 40’s-60’s decreased significantly.
Conclusions: A secular decrease in BMD, partly attributed to decreases in BMI, was observed in middle-aged Japanese women from 1995 to 2013. Measures to help maintain suitable BMI will be necessary to prevent a decrease in BMD among women.
References
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