教授挨拶
池田和彦 Ikeda Kazuhiko
輸血・移植免疫学講座 主任教授
福島県立医科大学 附属病院
輸血・移植免疫部 部長
私たちは、医師、検査技師、看護師が密接に協力しあいながら、造血細胞・免疫細胞の採取、輸血・移植関連検査、輸血製剤、細胞製剤、および再生医療製剤の管理・調整・出庫を通じて手術、移植医療、周産期医療、救急医療などの先進的・集学的な医療に携わっています。
最近、輸血療法においては、新たなエビデンスに基づいてガイドラインなどが大幅に改訂されてきました。また、臓器移植法の改定、造血幹細胞移植推進法、再生医療新法など、関連する法律が続々と整備され、再生医療等製品（ヒト細胞加工製品）や自己フィブリン糊などの新たな製剤も続々と登場する中で、私たちの役割は、益々大きくなってきています。
教育では、医学教育コアカリキュラムにおいて、「輸血と移植」の項目が分類されており、それにしたがって医学部学生の系統講義、臨床実習を行っています。また、基礎と臨床の橋渡しの分野であることを活かし、基礎上級も担当しています。医師のみならず、輸血・移植・細胞治療に携わる看護師、検査技師など、様々な職種の育成が求められており、福島県立総合衛生学院の臨床検査学科の学生や、日本輸血・細胞治療学会の認定輸血看護師および認定検査技師の病院実習なども受け入れております。
これまで講座では、輸血関連移植片対宿主病 (TA-GVHD) 予防法 (製剤に対する放射線照射) の確立、C型肝炎ウイルス感染経路 (母児感染) の解明、母児間輸血現象の証明、血小板保存バッグや人工保存液の開発などの業績により輸血医療に大きく貢献し、この分野を世界的にリードしてきました。近年では、治療に用いる幹細胞の採取・輸注・機能再生における安全性、効率性、品質を向上させるべく、基礎的・臨床的な研究を数多く行っています。
研究成果を診療や検査に直結させ、安全で適正な輸血療法の推進、移植医療の進歩や新たな細胞治療の開発・発展に貢献することを目指しています。
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With patients at the center of our health care universe, we cooperate with doctors, medical technologists, nurses, and others in specialties such as surgery, transplantation, hematology, perinatal care, and emergency medicine. In addition to our stewardship of allogeneic blood products supplied by the Japanese Red Cross, and complete "vein-to-vein" management of autologous blood, we are responsible for testing and processing progenitor cell and immune cell products, and we provide comprehensive laboratory services to support transfusion, transplantation, and cell therapy.
Evidence-based medicine (EBM) is the basis for our development of new guidelines, as well as our implementation of guidelines developed elsewhere. We must also reconcile emerging best practices with the laws and ethics of society at large, an iterative process in which we are active locally, nationally, and globally
The emerging field of regenerative medicine is also commanding our attention, as it calls for human cells to be processed ex vivo for new therapeutic purposes. Meanwhile, we continue to be involved with blood derivatives such as fibrin glue, used as a hemostatic agent in surgery and trauma care.
As a medical school department, we are responsible for lecture- and laboratory-based education in the "transfusion and transplantation" core curriculum. We also welcome 4th year medical students to research topics of mutual interest in a two-month rotation intended to bridge the basic science and clinical care phases of their education.
Now, our education mandate includes the nursing and medical technology professions, whose members may study with us to earn specialty credentials from the Japan Society of Transfusion Medicine and Cell Therapy. For many years, we have also dispatched teachers to the Fukushima Prefectural General Hygiene Institute, and hosted week-long rotations for their laboratory technology students. Starting in 2021, the curricula of that institute will be incorporated into FMU's new School of Allied Health Sciences.
Historically our contributions to transfusion medicine include prophylaxis of transfusion-associated graft-versus-host disease (TA-GVHD) by irradiation of cellular blood components, elucidation of vertical transmission of hepatitis C virus in utero, laboratory assessment of fetomaternal hemorrhage, development of a novel platelet storage solution, and biophysical evaluation of platelet storage bags with enhanced oxygen permeability.
More recently, we have conducted many basic science and clinical studies aimed at improving safety, efficiency, and quality throughout all phases of stem cell collection, infusion, and in vivo functional regeneration.
From bench to bedside, we aspire to improve medical diagnostics, therapeutic interventions, and patient outcomes.