Waseda University   School of Advanced Science and Engineering   Part-time Lecturer

2017.4 - Now

Tokyo Medical and Dental University   Part-time Lecturer

2015.4 - 2024.3

National Center for Global Health and Medicine   Biostatistics Section, Clinical Research Center   Section Chief

2012.8 - 2019.8

National Surgical Adjuvant Breast and Bowl Project/University of Pittsburgh   Pathology Lab/ Department of Biostatistics   Biostaitstics/Bioinformatics Specialist   Adjunct Research Assistant Professor

2010.12 - 2012.7

Dana Farber Research Institute, Harvard University   Dept. Medical Oncology   Bioinformatics analyst

2009.9 - 2010.9

Grad School of Public Health, Harvard University   Dept.Biostatistics   Visiting Scientist

2007.9

RIKEN   Research Scientist

2007.4 - 2007.8

Grad School of Medicin, the University of Tokyo   Clinical Bioinformatics Research Unit   Project Assistant Professor

2004.4 - 2007.3

計量生物学会

Accuracy of Death Certificates and Assessment of Factors for Misclassification of Underlying Cause of Death

Makiko Naka Mieno, Noriko Tanaka, Tomio Arai, Takuya Kawahara, Aya Kuchiba, Shizukiyo Ishikawa, Motoji Sawabe

JOURNAL OF EPIDEMIOLOGY   26 ( 4 )   191 - 198   2016.4（ ISSN:0917-5040 ）

DNA methylation profiling can classify HIV-associated lymphomas

Matsunaga, A., Hishima, T., Tanaka, N., Yamasaki, M., Yoshida, L., Mochizuki, M., Tanuma, J., Oka, S., Ishizaka, Y., Shimura, M., Hagiwara, S.

AIDS   28 ( 4 )   503 - 510   2014.2（ ISSN:0269-9370 ）

A Survey on biostatistical consulting at Japanese medical institutes.

Tanaka N, Kawasaki Y, Kurosawa T, Toyo-oka L, Mieno MN, Ohotsu H, Matsuoka J

Jpn Pharmacol Ther   42 ( S1 )   s33 - s44   2014

Predicting Degree of Benefit From Adjuvant Trastuzumab in NSABP Trial B-31

Katherine L. Pogue-Geile, Chungyeul Kim, Jong-Hyeon Jeong, Noriko Tanaka, Hanna Bandos, Patrick G. Gavin, Debora Fumagalli, Lynn C. Goldstein, Nour Sneige, Eike Burandt, Yusuke Taniyama, Olga L. Bohn, Ahwon Lee, Seung-Il Kim, Megan L. Reilly, Matthew Y. Remillard, Nicole L. Blackmon, Seong-Rim Kim, Zachary D. Horne, Priya Rastogi, Louis Fehrenbacher, Edward H. Romond, Sandra M. Swain, Eleftherios P. Mamounas, D. Lawrence Wickerham, Charles E. Geyer, Joseph P. Costantino, Norman Wolmark, Soonmyung Paik

JNCI: Journal of the National Cancer Institute   105 ( 23 )   1782 - 1788   2013.12（ ISSN:0027-8874 ）

Defective Mismatch Repair and Benefit from Bevacizumab for Colon Cancer: Findings from NSABP C-08

Kay Pogue-Geile, Greg Yothers, Yusuke Taniyama, Noriko Tanaka, Patrick Gavin, Linda Colangelo, Nicole Blackmon, Corey Lipchik, Seong Rim Kim, Saima Sharif, Carmen Allegra, Nicholas Petrelli, Michael J. O’Connell, Norman Wolmark, Soonmyung Paik

JNCI: Journal of the National Cancer Institute   105 ( 13 )   989 - 992   2013.7（ ISSN:0027-8874 ）

Mutation Profiling and Microsatellite Instability in Stage II and III Colon Cancer: An Assessment of Their Prognostic and Oxaliplatin Predictive Value

Patrick G. Gavin, Linda H. Colangelo, Debora Fumagalli, Noriko Tanaka, Matthew Y. Remillard, Greg Yothers, Chungyeul Kim, Yusuke Taniyama, Seung Il Kim, Hyun Joo Choi, Nicole L. Blackmon, Corey Lipchik, Nicholas J. Petrelli, Michael J. O'Connell, Norman Wolmark, Soonmyung Paik, Kay L. Pogue-Geile

Clinical Cancer Research   18 ( 23 )   6531 - 6541   2012.12（ ISSN:1078-0432 ）

Low lipoprotein(a) concentration is associated with cancer and all-cause deaths: A population-based cohort study (the jms cohort study)

Sawabe, M., Tanaka, N., Mieno, M.N., Ishikawa, S., Kayaba, K., Nakahara, K., Matsushita, S.

PLoS ONE   7 ( 4 )   e31954 - e31954   2012.4（ ISSN:1932-6203 ）

Novel Application of Structural Equation Modeling to Correlation Structure Analysis of CpG Island Methylation in Colorectal Cancer

Noriko Tanaka, Curtis Huttenhower, Katsuhiko Nosho, Yoshifumi Baba, Kaori Shima, John Quackenbush, Kevin M. Haigis, Edward Giovannucci, Charles S. Fuchs, Shuji Ogino

AMERICAN JOURNAL OF PATHOLOGY   177 ( 6 )   2731 - 2740   2010.12（ ISSN:0002-9440 ）

Mitochondrial DNA variants in a Japanese population of patients with Alzheimer's disease

Noriko Tanaka, Yu-ichi Goto, Jun Akanuma, Mayuko Kato, Toru Kinoshita, Fumio Yamashita, Masashi Tanaka, Takashi Asada

MITOCHONDRION   10 ( 1 )   32 - 37   2010.1（ ISSN:1567-7249 ）

High lipoprotein(a) level promotes both coronary atherosclerosis and myocardial infarction: a path analysis using a large number of autopsy cases

M. Sawabe, N. Tanaka, K. Nakahara, A. Hamamatsu, K. Chida, T. Arai, K. Harada, T. Inamatsu, T. Ozawa, M. M. Naka, S. Matsushita

HEART   95 ( 24 )   1997 - 2002   2009.12（ ISSN:1355-6037 ）

Role of DNA repair systems in malignant tumor development in the elderly

Tomio Arai, Motoji Sawabe, Takayuki Hosoi, Noriko Tanaka

Geriatrics & Gerontology International   8 ( 2 )   65 - 72   2008.6（ ISSN:1444-1586 ）

Optimum two-stage designs in case-control association studies using false discovery rate

Aya Kuchiba, Noriko Y. Tanaka, Yasuo Ohashi

JOURNAL OF HUMAN GENETICS   51 ( 12 )   1046 - 1054   2006（ ISSN:1434-5161 ）

Developments of geriatric autopsy database and Internet-based database of Japanese single nucleotide polymorphisms for geriatric research (JG-SNP)

Motoji Sawabe, Tomio Arai, Ichiro Kasahara, Yukiyoshi Esaki, Ken-ichi Nakahara, Takayuki Hosoi, Hajime Orimo, Kaiyo Takubo, Shigeo Murayama, Noriko Tanaka

Mechanisms of Ageing and Development   125 ( 8 )   547 - 552   2004.8（ ISSN:0047-6374 ）

Log-linear models for assessing gene-age interaction and their application to case-control studies of the apolipoprotein E (apoE) gene in Alzheimer's disease

N Tanaka, T Kinoshita, T Asada, Y Ohashi

JOURNAL OF HUMAN GENETICS   48 ( 10 )   520 - 524   2003.10（ ISSN:1434-5161 ）

Alcohol consumption and risk of dementia

Noriko Tanaka, Takashi Asada, Toru Kinoshita, Fumio Yamashita, Masatake Uno

The Lancet   360 ( 9331 )   491 - 491   2002.8（ ISSN:0140-6736 ）

Outcomes of patients with unstable circulation transported by a physician-staffed helicopter using the keyword method in Japan(タイトル和訳中)

Yanagawa Youichi, Nagasawa Hiroki, Maekawa Chihiro, Tanaka Noriko, Ota Soichiro, Ohsaka Hiromichi, Omori Kazuhiko

Journal of Rural Medicine   20 ( 4 )   276 - 281   2025.10（ ISSN:1880-487X ）

生物統計学　その歴史と医学分野への貢献

田中 紀子

MHC: Major Histocompatibility Complex   32 ( 2 )   68 - 79   2025.8（ ISSN:2186-9995 ）

Clinical significance of C-reactive protein in patients with severe fever with thrombocytopenia syndrome(タイトル和訳中)

Yanagawa Youichi, Maekawa Chihiro, Tanaka Noriko, Suda Namiko, Kawai Kenji, Hamada Michika, Ota Soichiro

Journal of Rural Medicine   20 ( 2 )   66 - 70   2025.4（ ISSN:1880-487X ）

炎症性腸疾患患者におけるチオプリン製剤の代謝に影響を及ぼす治療薬と患者背景(Therapeutic Agents and Patient Characteristics Affecting Metabolism of Thiopurines in Patients with Inflammatory Bowel Disease)

Aizawa Masato, Suzuki Kohei, Nakajima Yuki, Utano Kenichi, Tamazawa Kana, Ueda Kenta, Wada Jun, Sato Kentaro, Shibukawa Goro, Tanaka Noriko, Togashi Kazutomo

Fukushima Journal of Medical Science   71 ( 1 )   47 - 55   2025.1（ ISSN:0016-2590 ）

Introduction to biostatistics ─Its history and contribution to medical science─

Tanaka Noriko

Major Histocompatibility Complex   32 ( 2 )   68 - 79   2025（ ISSN:21869995 ）

Therapeutic Agents and Patient Characteristics Affecting Metabolism of Thiopurines in Patients with Inflammatory Bowel Disease

Aizawa Masato, Suzuki Kohei, Nakajima Yuki, Utano Kenichi, Tamazawa Kana, Ueda Kenta, Wada Jun, Sato Kentaro, Shibukawa Goro, Tanaka Noriko, Togashi Kazutomo

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE   advpub ( 0 )   47 - 55   2024（ ISSN:00162590 ）

Lack of significant associations between single nucleotide polymorphisms in LPAL2-LPA genetic region and all cancer incidence and mortality in Japanese population: The Japan public health center-based prospective study

Mieno M.N., Yamasaki M., Kuchiba A., Yamaji T., Ide K., Tanaka N., Sawada N., Inoue M., Tsugane S., Sawabe M., Iwasaki M.

Cancer Epidemiology   85   2023.8（ ISSN:18777821 ）

Computer-Aided Diagnosis of Early-Stage Colorectal Cancer Using Non-Magnified Endoscopic White Light Images

Daiki Nemoto, Zhe Guo, Shinichi Katsuki, Takahito Takezawa, Ryo Maemoto, Keisuke Kawasaki, Ken Inoue, Takashi Akutagawa, Hirohito Tanaka, Koichiro Sato, Teppei Omori, Kunihiro Takanashi, Yoshikazu Hayashi, Yuki Nakajima, Yasuyuki Miyakura, Takayuki Matsumoto, Naohisa Yoshida, Motohiro Esaki, Toshio Uraoka, Hiroyuki Kato, Yuji Inoue, Boyuan Peng, Ruiyao Zhang, Takashi Hisabe, Tomoki Matsuda, Hironori Yamamoto, Noriko Tanaka, Alan Kawarai Lefor, Xin Zhu, Kazutomo Togashi

Gastrointestinal Endoscopy   98 ( 1 )   90 - 99.e4   2023.7（ ISSN:00165107 ）

Lack of Significant Associations between Single Nucleotide Polymorphisms in LPAL2-LPA Genetic Region and Cancer Incidence and Mortality in Japanese Population: The Japan Public Health Center-Based Prospective Study

Makiko Naka Mieno, Maria Yamasaki, Aya Kuchiba, Taiki Yamaji, Keigo Ide, Noriko Tanaka, Norie Sawada, Manami Inoue, Shoichiro Tsugane, Motoji Sawabe, Motoki Iwasaki

SSRN Electronic Journal   2023

Risk of Delayed Bleeding after Cold Snare Polypectomy in Patients with Antithrombotic Therapy

Masato Aizawa, Kenichi Utano, Daiki Nemoto, Noriyuki Isohata, Shungo Endo, Noriko Tanaka, David G. Hewett, Kazutomo Togashi

Digestive Diseases and Sciences   67 ( 5 )   1869 - 1878   2022.5（ ISSN:01632116 ）

Autopsy Validation of the Diagnostic Accuracy of 123I-Metaiodobenzylguanidine Myocardial Scintigraphy for Lewy Body Disease.

Tomoyasu Matsubara, Masashi Kameyama, Noriko Tanaka, Renpei Sengoku, Makoto Orita, Ko Furuta, Atsushi Iwata, Tomio Arai, Hirofumi Maruyama, Yuko Saito, Shigeo Murayama

Neurology   98 ( 16 )   E1648 - E1659   2022.3（ ISSN:00283878 ）

剖検脳を用いたLewy小体病診断における¹²³I-MIBG心筋シンチグラフィの診断能実証研究

松原知康, 松原知康, 亀山征史, 田中紀子, 仙石錬平, 織田麻琴, 織田麻琴, 古田光, 岩田淳, 新井冨生, 丸山博文, 齊藤祐子, 村山繁雄, 村山繁雄

日本神経学会学術大会プログラム・抄録集   63rd ( Suppl. )   S305 - S305   2022（ ISSN:0009-918X ）

Predictors of severe sepsis-related in-hospital mortality based on a multicenter cohort study

Akiyoshi Hagiwara, Noriko Tanaka, Yosuke Inaba, Satoshi Gando, Atsushi Shiraishi, Daizoh Saitoh, Yasuhiro Otomo, Hiroto Ikeda, Hiroshi Ogura, Shigeki Kushimoto, Joji Kotani, Yuichiro Sakamoto, Yasukazu Shiino, Shin-ichiro Shiraishi, Kiyotsugu Takuma, Takehiko Tarui, Ryosuke Tsuruta, Taka-aki Nakada, Toru Hifumi, Kazuma Yamakawa, Naoshi Takeyama, Norio Yamashita, Toshikazu Abe, Masashi Ueyama, Kohji Okamoto, Junichi Sasaki, Tomohiko Masuno, Toshihiko Mayumi, Seitaro Fujishima, Yutaka Umemura, Satoshi Fujimi

Medicine   100 ( 8 )   e24844 - e24844   2021.2（ ISSN:0025-7974 ）

Comparison of 18F-FDG PET/CT and 67Ga-SPECT for the diagnosis of fever of unknown origin: a multicenter prospective study in Japan

Kazuo Kubota, Noriko Tanaka, Yoko Miyata, Hiroshi Ohtsu, Tadaki Nakahara, Setsu Sakamoto, Takashi Kudo, Yoshihiro Nishiyama, Ukihide Tateishi, Koji Murakami, Yuji Nakamoto, Yasuyuki Taki, Tomohiro Kaneta, Joji Kawabe, Shigeki Nagamachi, Tsuyoshi Kawano, Jun Hatazawa, Youichi Mizutani, Shingo Baba, Kazukuni Kirii, Kunihiko Yokoyama, Terue Okamura, Masashi Kameyama, Ryogo Minamimoto, Junwa Kunimatsu, On Kato, Hiroyuki Yamashita, Hiroshi Kaneko, Satoshi Kutsuna, Norio Ohmagari, Akiyoshi Hagiwara, Yoshimi Kikuchi, Masao Kobayakawa

Annals of Nuclear Medicine   35 ( 1 )   31 - 46   2021.1（ ISSN:09147187 ）

不明熱診断に対する18F-FDG PET/CTと68Ga-SPECTの比較検討　日本国内多施設前向き研究(Comparison of 18F-FDG PET/CT and 67Ga-SPECT for the diagnosis of fever of unknown origin: a multicenter prospective study in Japan)

Kubota Kazuo, Tanaka Noriko, Miyata Yoko, Ohtsu Hiroshi, Nakahara Tadaki, Sakamoto Setsu, Kudo Takashi, Nishiyama Yoshihiro, Tateishi Ukihide, Murakami Koji, Nakamoto Yuji, Taki Yasuyuki, Kaneta Tomohiro, Kawabe Joji, Nagamachi Shigeki, Kawano Tsuyoshi, Hatazawa Jun, Mizutani Youichi, Baba Shingo, Kirii Kazukuni, Yokoyama Kunihiko, Okamura Terue, Kameyama Masashi, Minamimoto Ryogo, Kunimatsu Junwa, Kato On, Yamashita Hiroyuki, Kaneko Hiroshi, Kutsuna Satoshi, Ohmagari Norio, Hagiwara Akiyoshi, Kikuchi Yoshimi, Kobayakawa Masao

Annals of Nuclear Medicine   35 ( 1 )   31 - 46   2021.1（ ISSN:0914-7187 ）

マルコフ連鎖モンテカルロ法を用いた左側打ち切りデータからのベイズ推定の試み　ミネラルウォーター製品のCr(VI)濃度の検討(Attempt of Bayesian Estimation from Left-censored Data Using the Markov Chain Monte Carlo Method: Exploring Cr(VI) Concentrations in Mineral Water Products)

Suzuki Yoshinari, Tanaka Noriko, Akiyama Hiroshi

Food Safety   8 ( 4 )   67 - 89   2020.12

Oryeongsan(五苓散)は実験的自己免疫性脳脊髄炎を緩和する(Oryeongsan(Goreisan) Ameliorates Experimental Autoimmune Encephalomyelitis)

Inada Rino, Miyamoto Katsuichi, Tanaka Noriko, Moriguchi Kota, Kusunoki Susumu

Internal Medicine   59 ( 1 )   55 - 60   2020.1（ ISSN:0918-2918 ）

Attempt of Bayesian Estimation from Left-censored Data Using the Markov Chain Monte Carlo Method: Exploring Cr(VI) Concentrations in Mineral Water Products

Yoshinari Suzuki, Noriko Tanaka, Hiroshi Akiyama

Food Safety   8 ( 4 )   67 - 89   2020（ ISSN:2187-8404 ）

Late-stage myeloma invades kidney without significant effect on renal function: findings from 53 autopsies in a single institute

Junichiro Takano, Sohtaro Mine, Makoto Mochizuki, Noriko Tanaka, Shotaro Hagiwara

International Journal of Hematology   109 ( 2 )   147 - 153   2019.2（ ISSN:0925-5710 ）

Development of a new clinical decision rule for cervical CT to detect cervical spine injury in patients with head or neck trauma

Inagaki, T., Kimura, A., Makishi, G., Tanaka, S., Tanaka, N.

Emergency Medicine Journal   35 ( 10 )   614 - 618   2018.10（ ISSN:1472-0213 ）

Establishment of Japan Brain Bank Net

Saito Y, Kakita A, Yoshida M, Murayama S, Iritani S, Yokota O, Terada S, Ohshima K, Yasuto K, Yabe H, Inoue Y, Tanaka N, Motoyoshi Y, Murata M, Mizusawa H

JOURNAL OF THE NEUROLOGICAL SCIENCES   381   963-963   2017.10（ ISSN:0022-510X ）

Short-Term Safety and Efficacy of Balloon-Occluded Retrograde Transvenous Obliteration Using Ethanolamine Oleate: Results of a Prospective, Multicenter, Single-Arm Trial

Kobayakawa, M., Kokubu, S., Hirota, S., Koizumi, J., Nishida, N., Yasumoto, T., Mochida, S., Hidaka, H., Tanaka, N., Tajima, T.

Journal of Vascular and Interventional Radiology   28 ( 8 )   1108 - 1115.e2   2017.8（ ISSN:1535-7732 ）

Can recombinant human thrombomodulin increase survival among patients with severe septic-induced disseminated intravascular coagulation: A single-centre, open-label, randomised controlled trial

Hagiwara, A., Tanaka, N., Uemura, T., Matsuda, W., Kimura, A.

BMJ Open   6 ( 12 )   e012850 - e012850   2016.12（ ISSN:2044-6055 ）

Urinary β2 microglobulin can predict tenofovir disoproxil fumarate-related renal dysfunction in HIV-1-infected patients who initiate tenofovir disoproxil fumarate-containing antiretroviral therapy

Nishijima, T., Kurosawa, T., Tanaka, N., Kawasaki, Y., Kikuchi, Y., Oka, S., Gatanaga, H.

AIDS   30 ( 10 )   1563 - 1571   2016.6（ ISSN:1473-5571 ）

医学統計コンサルテーションの実施状況の多施設比較

田中 紀子, 三重野 牧子, 黒澤 匠雅, 大津 洋, 松岡 淨

薬理と治療   44 ( Suppl.1 )   s67 - s71   2016.5（ ISSN:0386-3603 ）

Biostatistical consulting at medical institutes in Japan: A multicenter survey

Tanaka N., Mieno M., Kurosawa T., Ohtsu H., Matsuoka J.

Japanese Pharmacology and Therapeutics   44   s67 - s71   2016（ ISSN:03863603 ）

Biostatistical consulting at medical institutes in Japan: A multicenter survey

Tanaka, N., Mieno, M., Kurosawa, T., Ohtsu, H., Matsuoka, J.

Japanese Pharmacology and Therapeutics   44   2016（ ISSN:0386-3603 ）

Drug transporter genetic variants are not associated with TDF-related renal dysfunction in patients with HIV-1 infection: A pharmacogenetic study

Nishijima, T., Hayashida, T., Kurosawa, T., Tanaka, N., Oka, S., Gatanaga, H.

PLoS ONE   10 ( 11 )   e0141931 - e0141931   2015.11（ ISSN:1932-6203 ）

Neurodegenerative changes in patients with clinical history of bipolar disorders

Ayako Shioya, Yuko Saito, Kunimasa Arima, Yukio Kakuta, Takefumi Yuzuriha, Noriko Tanaka, Shigeo Murayama, Akira Tamaoka

Neuropathology   35 ( 3 )   245 - 253   2015.6（ ISSN:0919-6544 ）

国立国際医療研究センターにおける医学統計コンサルテーションに関する実施状況

川崎 洋平, 田中 紀子, 黒澤 匠雅, 豊岡 理人, 三重野 牧子, 大津 洋, 松岡 淨

薬理と治療   43 ( Suppl.1 )   s85 - s93   2015.5（ ISSN:0386-3603 ）

Reply to 'How does weight influence tenofovir disoproxil-fumarate induced renal function decline?'

Nishijima, T., Kawasaki, Y., Tanaka, N., Gatanaga, H., Oka, S.

AIDS   29 ( 5 )   645 - 647   2015.3（ ISSN:1473-5571 ）

An introduction of biostatistical consulting operation procedure at national center for global health and medicine

Kawasaki Y., Tanaka N., Kurosawa T., Toyo-Oka L., Mieno M.N., Ohtsu H., Matsuoka J.

Japanese Pharmacology and Therapeutics   43   s85 - s93   2015（ ISSN:03863603 ）

An introduction of biostatistical consulting operation procedure at national center for global health and medicine

Kawasaki, Y., Tanaka, N., Kurosawa, T., Toyo-Oka, L., Mieno, M.N., Ohtsu, H., Matsuoka, J.

Japanese Pharmacology and Therapeutics   43   2015（ ISSN:0386-3603 ）

Single-nucleotide polymorphisms in the UDP-glucuronosyltransferase 1A-3' untranslated region are associated with atazanavir-induced nephrolithiasis in patients with HIV-1 infection: a pharmacogenetic study

T. Nishijima, K. Tsuchiya, N. Tanaka, A. Joya, Y. Hamada, D. Mizushima, T. Aoki, K. Watanabe, E. Kinai, H. Honda, H. Yazaki, J. Tanuma, K. Tsukada, K. Teruya, Y. Kikuchi, S. Oka, H. Gatanaga

Journal of Antimicrobial Chemotherapy   69 ( 12 )   3320 - 3328   2014.12（ ISSN:0305-7453 ）

Significant association between hypolipoproteinemia(a) and lifetime risk of cancer: An autopsy study from a community-based Geriatric Hospital

Mieno, M.N., Sawabe, M., Tanaka, N., Nakahara, K.-I., Hamamatsu, A., Chida, K., Sakurai, U., Arai, T., Harada, K., Mori, S., Inamatsu, T., Ozawa, T., Honma, N., Aida, J., Takubo, K., Matsushita, S.

Cancer Epidemiology   38 ( 5 )   550 - 555   2014.10（ ISSN:1877-783X ）

Long-term exposure to tenofovir continuously decrease renal function in HIV-1-infected patients with low body weight

Takeshi Nishijima, Yohei Kawasaki, Noriko Tanaka, Daisuke Mizushima, Takahiro Aoki, Koji Watanabe, Ei Kinai, Haruhito Honda, Hirohisa Yazaki, Junko Tanuma, Kunihisa Tsukada, Katsuji Teruya, Yoshimi Kikuchi, Hiroyuki Gatanaga, Shinichi Oka

AIDS   28 ( 13 )   1903 - 1910   2014.8（ ISSN:0269-9370 ）

A survey on biostatistical consulting at Japanese medical institutes

Tanaka N., Kawasaki Y., Kurosawa T., Toyooka L., Mieno M., Ohtsu H., Matsuoka J.

Japanese Pharmacology and Therapeutics   42 ( SUPPL. 1 )   s33 - s44   2014（ ISSN:03863603 ）

A survey on biostatistical consulting at Japanese medical institutes

Tanaka, N., Kawasaki, Y., Kurosawa, T., Toyooka, L., Mieno, M., Ohtsu, H., Matsuoka, J.

Japanese Pharmacology and Therapeutics   42 ( SUPPL. 1 )   2014（ ISSN:0386-3603 ）

Whole-body computed tomography is associated with decreased mortality in blunt trauma patients with moderate-to-severe consciousness disturbance: A multicenter, retrospective study

Kimura, A., Tanaka, N.

Journal of Trauma and Acute Care Surgery   75 ( 2 )   202 - 206   2013.8（ ISSN:2163-0755 ）

Association between estrogen receptor-β dinucleotide repeat polymorphism and incidence of femoral fracture

Naoko Honma, Seijiro Mori, Heying Zhou, Shinobu Ikeda, Makiko Naka Mieno, Noriko Tanaka, Kaiyo Takubo, Tomio Arai, Motoji Sawabe, Masaaki Muramatsu, Hideki Ito

Journal of Bone and Mineral Metabolism   31 ( 1 )   96 - 101   2013.1（ ISSN:0914-8779 ）

DNA mismatch repair deficiency and benefit from adjuvant bevacizumab in NSABP C-08: Molecular profiling results

Katherine L. Pogue-Geile, Noriko Tanaka, Patrick Gavin, Greg Yothers, Linda H. Colangelo, Chungyeul Kim, Seong-Rim Kim, Debora Fumagalli, Yusuke Taniyama, Saima Sharif, Michael J. O'Connell, Soonmyung Paik

JOURNAL OF CLINICAL ONCOLOGY   30 ( 30 )   2012.10（ ISSN:0732-183X ）

Predictors of lymph node count in colorectal cancer resections: Data from US nationwide prospective cohort studies

Morikawa, T., Tanaka, N., Kuchiba, A., Nosho, K., Yamauchi, M., Hornick, J.L., Swanson, R.S., Chan, A.T., Meyerhardt, J.A., Huttenhower, C., Schrag, D., Fuchs, C.S., Ogino, S.

Archives of Surgery   147 ( 8 )   715 - 723   2012.8（ ISSN:0004-0010 ）

No evidence for interference of H and E staining in DNA testing: usefulness of DNA extraction from H&E-stained archival tissue sections.

Morikawa T, Shima K, Kuchiba A, Yamauchi M, Tanaka N, Imamura Y, Liao X, Qian ZR, Brahmandam M, Longtine JA, Lindeman NI, Fuchs CS, Ogino S

American journal of clinical pathology   138 ( 1 )   122 - 129   2012.7（ ISSN:0002-9173 ）

Polymorphisms of LTA, LGALS2, and PSMA6 genes and coronary atherosclerosis: A pathological study of 1503 consecutive autopsy cases

Ikeda, S., Tanaka, N., Arai, T., Chida, K., Muramatsu, M., Sawabe, M.

Atherosclerosis   221 ( 2 )   458 - 460   2012.4（ ISSN:0021-9150 ）

Association of fucosyltransferase 8 (FUT8) polymorphism Thr267Lys with pulmonary emphysema

Miki Yamada, Takeo Ishii, Shinobu Ikeda, Makiko Naka-Mieno, Noriko Tanaka, Tomio Arai, Toshio Kumasaka, Akihiko Gemma, Kozui Kida, Masaaki Muramatsu, Motoji Sawabe

Journal of Human Genetics   56 ( 12 )   857 - 860   2011.12（ ISSN:1434-5161 ）

Oestrogen receptor-β CA repeat polymorphism is associated with incidence of colorectal cancer among females

Honma, N., Arai, T., Takubo, K., Younes, M., Tanaka, N., Mieno, M.N., Tamura, K., Ikeda, S., Sawabe, M., Muramatsu, M.

Histopathology   59 ( 2 )   216 - 224   2011.8（ ISSN:0309-0167 ）

LOW LIPOPROTEIN(A) CONCENTRATION IS ASSOCIATED WITH SHORTER SURVIVAL: A POPULATION-BASED COHORT STUDY (THE JMS COHORT STUDY)

M. Sawabe, N. Tanaka, M. N. Mieno, S. Ishikawa, K. Kayaba, K. Nakahara, S. Matsushita

ATHEROSCLEROSIS SUPPLEMENTS   12 ( 1 )   16 - 16   2011.6（ ISSN:1567-5688 ）

STAT3 expression, molecular features, inflammation patterns, and prognosis in a database of 724 colorectal cancers.

Morikawa T, Baba Y, Yamauchi M, Kuchiba A, Nosho K, Shima K, Tanaka N, Huttenhower C, Frank DA, Fuchs CS, Ogino S

Clinical cancer research : an official journal of the American Association for Cancer Research   17 ( 6 )   1452 - 1462   2011.3（ ISSN:1078-0432 ）

Mitochondrial haplogroups A and M7a confer a genetic risk for coronary atherosclerosis in the japanese Elderly: An autopsy study of 1,536 patients

Sawabe, M., Tanaka, M., Chida, K., Arai, T., Nishigaki, Y., Fuku, N., Mieno, M.N., Kuchiba, A., Tanaka, N.

Journal of Atherosclerosis and Thrombosis   18 ( 2 )   166 - 175   2011（ ISSN:1880-3873 ）

Hypomethylation of the IGF2 DMR in colorectal tumors, detected by bisulfite pyrosequencing, is associated with poor prognosis.

Baba Y, Nosho K, Shima K, Huttenhower C, Tanaka N, Hazra A, Giovannucci EL, Fuchs CS, Ogino S

Gastroenterology   139 ( 6 )   1855 - 1864   2010.12（ ISSN:0016-5085 ）

Tumour-infiltrating T-cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review.

Nosho K, Baba Y, Tanaka N, Shima K, Hayashi M, Meyerhardt JA, Giovannucci E, Dranoff G, Fuchs CS, Ogino S

The Journal of pathology   222 ( 4 )   350 - 366   2010.12（ ISSN:0022-3417 ）

Polymorphism of SERPINE2 gene is associated with pulmonary emphysema in consecutive autopsy cases

Fujimoto, K., Ikeda, S., Arai, T., Tanaka, N., Kumasaka, T., Ishii, T., Kida, K., Muramatsu, M., Sawabe, M.

BMC Medical Genetics   11 ( 1 )   2010.12（ ISSN:1471-2350 ）

Epigenomic diversity of colorectal cancer indicated by LINE-1 methylation in a database of 869 tumors.

Baba Y, Huttenhower C, Nosho K, Tanaka N, Shima K, Hazra A, Schernhammer ES, Hunter DJ, Giovannucci EL, Fuchs CS, Ogino S

Molecular cancer   9 ( 1 )   125 - 125   2010.5（ ISSN:1476-4598 ）

KRAS and BRAF mutations influence correlation structure of locus-specific CpG island methylation and CIMP in colorectal cancer

Shuji Ogino, Noriko Tanaka, Katsuhiko Nosho, Curtis Huttenhower, John Quackenbush, Kevin Haigis, Charles Fuchs

CANCER RESEARCH   70   2010.4（ ISSN:0008-5472 ）

The P86L common allele of CALHM1 does not influence risk for Alzheimer disease in Japanese cohorts.

Inoue, K, Tanaka, N, Yamashita, F, Sawano, Y, Asada, T, Goto, Y

Am J Med Genet B Neuropsychiatr Genet.   153B ( 2 )   532-535 - 535   2010.1（ ISSN:1552-4841 ）

High Lipoprotein(a) Level Promotes Both Coronary Atherosclerosis and Myocardial Infarction: A Path Analysis Using a Large Number of Autopsy Cases

Motoji Sawabe, Noriko Tanaka, Ken-ichi Nakahara, Akihiko Hamamatsu, Kouji Chida, Tomio Arai, Kazumasa Harada, Takashi Inamatsu, Toshio Ozawa, Makiko M. Naka, Satoru Matsushita

CIRCULATION   120 ( 18 )   S528 - S528   2009.11（ ISSN:0009-7322 ）

Lymphocytic reaction to colorectal cancer is associated with longer survival, independent of lymph node count, microsatellite instability, and CpG island methylator phenotype.

Ogino S, Nosho K, Irahara N, Meyerhardt JA, Baba Y, Shima K, Glickman JN, Ferrone CR, Mino-Kenudson M, Tanaka N, Dranoff G, Giovannucci EL, Fuchs CS

Clinical cancer research : an official journal of the American Association for Cancer Research   15 ( 20 )   6412 - 6420   2009.10（ ISSN:1078-0432 ）

OE-393 High Lipoprotein(a) Level has Equal Positive Effects on Coronary Atherosclerosis and Myocardial Infarction : A Path Analysis Using 1,062 Autopsy Cases(OE66,Atherosclerosis (Clinical/Pathophysiology) (IHD),Oral Presentation (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)

Sawabe Motoji, Tanaka Noriko, Nakahara Ken-ichi, Matsushita Satoru, Hamamatsu Akihiko, Chida Koji, Harada Kazumasa, Ozawa Toshio

Circulation journal : official journal of the Japanese Circulation Society   73   274 - 274   2009.3（ ISSN:1346-9843 ）

Smoking Confers a MTHFR 677C&rt;T Genotype-Dependent Risk for Systemic Atherosclerosis: Results from a Large Number of Elderly Autopsy Cases that Died in a Community-Based General Geriatric Hospital

Motoji Sawabe, Tomio Arai, Atsushi Araki, Takayuki Hosoi, Aya Kuchiba, Noriko Tanaka, Takahiro Naito, Kanae Oda, Shinobu Ikeda, Masaaki Muramatsu

Journal of Atherosclerosis and Thrombosis   16 ( 2 )   91 - 104   2009（ ISSN:1340-3478 ）

Lymphotoxin-alpha polymorphisms and presence of cancer in 1,536 consecutive autopsy cases

Takei, K., Ikeda, S., Arai, T., Tanaka, N., Muramatsu, M., Sawabe, M.

BMC Cancer   8 ( 1 )   2008.12（ ISSN:1471-2407 ）

Incidence and Extent of Lewy Body-Related α-Synucleinopathy in Aging Human Olfactory Bulb

Renpei Sengoku, Yuko Saito, Masako Ikemura, Hiroyuki Hatsuta, Yoshio Sakiyama, Kazutomi Kanemaru, Tomio Arai, Motoji Sawabe, Noriko Tanaka, Hideki Mochizuki, Kiyoharu Inoue, Shigeo Murayama

Journal of Neuropathology & Experimental Neurology   67 ( 11 )   1072 - 1083   2008.11（ ISSN:0022-3069 ）

FRS-101 Mitochondrial Haplogroup M7a Confers a Genetic Risk for Coronary Atherosclerosis in the Elderly : An Autopsy Study of 1,536 Patients(Clinical Frontiers in Atherosclerosis(IHD),Featured Research Session,The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Sawabe Motoji, Chida Kouji, Tanaka Noriko

Circulation journal : official journal of the Japanese Circulation Society   72   171 - 171   2008.3（ ISSN:1346-9843 ）

PJ-439 Hypercholesteremia is the Strongest Risk Factor for Autopsy-Verified Coronary Stenosis in the Elderly Women(Coronary circulation, basic/clinical(04)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Naito Takahiro, Chida Kouji, Hamamatsu Akihiko, Harada Kazumasa, Ozawa Toshio, Tanaka Noriko, Sawabe Motoji

Circulation journal : official journal of the Japanese Circulation Society   72   622 - 623   2008.3（ ISSN:1346-9843 ）

OJ-158 Smoking Confers a MTHFR 677C>T Genotype-Dependent Risk for Systemic Atherosclerosis(Smoking(H),Oral Presentation (Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)

Sawabe Motoji, Tanaka Noriko, Naito Takahiro, Oda Kanae, Muramatsu Masaaki

Circulation journal : official journal of the Japanese Circulation Society   72   328 - 328   2008.3（ ISSN:1346-9843 ）

Genomic approaches to bone and joint diseases. Statistics in genetic epidemiology

Tanaka N.

Clinical Calcium   18 ( 2 )   182 - 187   2008.2（ ISSN:09175857 ）

Elderly Patients With Minimal Common Carotid Atherosclerosis Not Infrequently Have Severe Coronary Atherosclerosis and Myocardial Infarction

Motoji Sawabe, Akihiko Hamamatsu, Kouji Chida, Tomio Arai, Kazumasa Harada, Toshio Ozawa, Noriko Tanaka

Circulation Journal   72 ( 12 )   1946 - 1952   2008（ ISSN:1346-9843 ）

Genomic approaches to bone and joint diseases. Statistics in genetic epidemiology

Tanaka, N.

Clinical calcium   18 ( 2 )   2008（ ISSN:0917-5857 ）

Discordance between carotid and coronary atherosclerosis: A potential pitfall of carotid ultrasonography

M. Sawabe, A. Hamamatsu, K. Chida, K. Harada, T. Ozawa, T. Naito, K. Oda, M. Muramatsu, N. Tanaka

ATHEROSCLEROSIS SUPPLEMENTS   8 ( 1 )   136 - 136   2007.6（ ISSN:1567-5688 ）

Polymorphisms in pro- and anti-inflammatory cytokine genes and susceptibility to atherosclerosis: a pathological study of 1503 consecutive autopsy cases

Kanae Oda, Noriko Tanaka, Tomio Arai, Jungo Araki, Yixuan Song, Ling Zhang, Aya Kuchiba, Takayuki Hosoi, Takuji Shirasawa, Masaaki Muramatsu, Motoji Sawabe

Human Molecular Genetics   16 ( 6 )   592 - 599   2007.3（ ISSN:0964-6906 ）

FRS-032 Discordance between Carotid and Coronary Atherosclerosis : An Analysis of 1, 570 Autopsy Cases of the Japanese Elderly(Pathophysiology of Cardiovascular Disease, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Sawabe Motoji, Hamamatsu Akihiko, Chida Koji, Harada Kazumasa, Ozawa Toshio, Naito Takahiro, Oda Kanae, Muramatsu Masaaki, Tanaka Noriko

Circulation journal : official journal of the Japanese Circulation Society   71   123 - 123   2007.3（ ISSN:1346-9843 ）

PJ-311 The Association between CETP Gene Promoter SNP Haplotype and Atherosclerotic Degrees in Different Arterial Systems : An Autopsy Study(Atherosclerosis, clinical-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

Naito Takahiro, Sawabe Motoji, Hamamatsu Akihiko, Chida Koji, Harada Kazumasa, Ozawa Toshio, Tanaka Noriko, Oda Kanae, Muramatsu Masaaki

Circulation journal : official journal of the Japanese Circulation Society   71   549 - 549   2007.3（ ISSN:1346-9843 ）

Sustained progression and loss of the gender-related difference in atherosclerosis in the very old: A pathological study of 1074 consecutive autopsy cases

Motoji Sawabe, Tomio Arai, Ichiro Kasahara, Akihiko Hamamatsu, Yukiyoshi Esaki, Ken-ichi Nakahara, Kazumasa Harada, Kouji Chida, Hiroshi Yamanouchi, Toshio Ozawa, Kaiyo Takubo, Shigeo Murayama, Noriko Tanaka

Atherosclerosis   186 ( 2 )   374 - 379   2006.6（ ISSN:0021-9150 ）

The contributions of the candidate genes to afherosulerosis are not uniform among the arterial systems

M. Sawabe, T. Arai, T. Hosoi, M. Muramatsu, K. Oda, N. Tanaka, T. Shirasawa

ATHEROSCLEROSIS SUPPLEMENTS   7 ( 3 )   129 - 129   2006.6（ ISSN:1567-5688 ）

FRS-005 The Associations between the Genetic Polymorphisms of Pro- and Anti-inflammatory Chemokine/Cytokines and the Atherosclerotic Degrees in the Japanese Elderly(Frontier of Atherosclerosis Research (H) FRS1,Featured Research Session,The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Oda Kanae, Sawabe Motoji, Tanaka Noriko, Shirasawa Takuji, Muramatsu Masaaki

Circulation journal : official journal of the Japanese Circulation Society   70   111 - 111   2006.3（ ISSN:1346-9843 ）

Semen quality of 324 fertile Japanese men

T. Iwamoto, S. Nozawa, M. Yoshiike, T. Hoshino, K. Baba, T. Matsushita, S.N. Tanaka, M. Naka, N.E. Skakkebæk, N. Jørgensen

Human Reproduction   21 ( 3 )   760 - 765   2006.3（ ISSN:0268-1161 ）

OE-061 The Contributions of the Candidate Genes to Atherosclerosis are Not Uniform among the Arterial Systems(Atherosclerosis, basic-1 (H) OE11,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)

Sawabe Motoji, Oda Kanae, Muramatsu Masaaki, Tanaka Noriko, Shirasawa Takuji

Circulation journal : official journal of the Japanese Circulation Society   70   163 - 164   2006.3（ ISSN:1346-9843 ）

Aortic pulse wave velocity and the degree of atherosclerosis in the elderly: A pathological study based on 304 autopsy cases

Sawabe, M., Takahashi, R., Matsushita, S., Ozawa, T., Arai, T., Hamamatsu, A., Nakahara, K.-I., Chida, K., Yamanouchi, H., Murayama, S., Tanaka, N.

Atherosclerosis   179 ( 2 )   345 - 351   2005.4（ ISSN:0021-9150 ）

Development and application of geriatric autopsy database and Internet-based database of Japanese single nucleolide polymorphisms for geriatric research (JG-SNP)

M Sawabe, T Arai, T Hosoi, K Takubo, N Tanaka

MODERN PATHOLOGY   18   9A - 9A   2005.1（ ISSN:0893-3952 ）

Sustained progression and loss of gender-related difference of the atherosclerosis in the very old: A pathological study of 1,074 consecutive autopsy cases

M Sawabe, T Atai, A Hamamatsu, K Chida, N Tanaka

LABORATORY INVESTIGATION   85   59A - 59A   2005.1（ ISSN:0023-6837 ）

Sustained progression and loss of gender-related difference of the atherosclerosis in the very old: A pathological study of 1,074 consecutive autopsy cases

M Sawabe, T Arai, A Hamamatsu, K Chida, N Tanaka

MODERN PATHOLOGY   18   59A - 59A   2005.1（ ISSN:0893-3952 ）

Staging of argyrophilic grains: An age-associated tauopathy

Saito, Y., Ruberu, N.N., Sawabe, M., Arai, T., Tanaka, N., Kakuta, Y., Yamanouchi, H., Murayama, S.

Journal of Neuropathology and Experimental Neurology   63 ( 9 )   911 - 918   2004.9（ ISSN:0022-3069 ）

Alcohol consumption and risk of dementia [5] (multiple letters)

Hans Liedholm, Agneta Björck Linné, Leo Sher, Ernest H. Friedman, Undurti N. Das, Annemieke Ruitenberg, Albert Hofman, Monique M. B. Breteler, Noriko Tanaka, Takashi Asada, Toru Kinoshita, Fumio Yamashita, Masatake Uno

Lancet   360 ( 9331 )   489 - 491   2002.8（ ISSN:0140-6736 ）

Application of log-linear model of inference on disease susceptibility gene effects under independence of genotype and age.

N Tanaka, T Kinoshita, T Asada, Y Ohashi

AMERICAN JOURNAL OF HUMAN GENETICS   69 ( 4 )   420 - 420   2001.10（ ISSN:0002-9297 ）