Updated on 2020/04/02

写真a

 
KOBAYASHI Kazuto
 
Organization
Research Facility Attached to the School of Medicine Department of Molecular Genetics Professor
Title
Professor

Degree

  • 農学博士 ( その他の授与機関 )

  • 医学博士 ( その他の授与機関 )

Research Interests

  • Tyrosine hydroxylase, Immunotoxin Cell targeting, Basal Ganglia, Neural Circuit, Transgenic mouse, Corpus Striatum

Research Areas

  • Life Science / Molecular biology  / Molecular Biology

  • Life Science / Neuroscience-general  / Neuro Science in General

Research History

  • Fukushima Medical University   Professor

    2017.2 - Now

Papers

  • Enhancement of the transduction efficiency of a lentiviral vector for neuron-specific retrograde gene delivery through the point mutation of fusion glycoprotein type E.

    Kato, S., Sugawara, M., Kobayashi, K., Kimura, K., Inoue, K., Takada, M., and Kobayashi, K.

    J Neurosci Methods   311   147 - 155   2019.1

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.jneumeth.2018.10.023

    PubMed

  • Monitoring and updating of action selection for goal-directed behavior through the striatal direct and indirect pathways.

    Nonomura S, Nishizawa K, Sakai Y, Kawaguchi Y, Kato S, Uchigashima M, Watanabe M, Yamanaka K, Enomoto K, Chiken S, Sano H, Soma S, Yoshida J, Samejima K, Ogawa M, Kobayashi K, Nambu A, Isomura Y, Kimura M.

    Neuron   99 ( 6 )   1302 - 1314   2018.9

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.neuron.2018.08.002

    PubMed

  • Chemical Landscape for Tissue Clearing Based on Hydrophilic Reagents.

    Tainaka K, Murakami TC, Susaki EA, Shimizu C, Saito R, Takahashi K, Hayashi-Takagi A, Sekiya H, Arima Y, Nojima S, Ikemura M, Ushiku T, Shimizu Y, Murakami M, Tanaka KF, Iino M, Kasai H, Sasaoka T, Kobayashi K, Miyazono K, Morii E, Isa T, Fukayama M, Kakita A, Ueda HR

    Cell Rep.   24 ( 8 )   2196 - 2210   2018.8

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.celrep.2018.07.056

    PubMed

  • Task-dependent function of striatal cholinergic interneurons in behavioural flexibility.

    Okada, K., Nishizawa, K, Setogawa, S., Hashimoto, K. and Kobayashi, K.

    Eur J Neurosci.   47 ( 10 )   1174 - 1183   2018.5

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1111/ejn.13768

    PubMed

  • Targeted expression of step-function opsins in transgenic rats for optogenetic studies.

    Igarashi H, Ikeda K, Onimaru H, Kaneko R, Koizumi K, Beppu K, Nishizawa K, Takahashi Y, Kato F, Matsui K, Kobayashi K, Yanagawa Y, Muramatsu SI, Ishizuka T, Yawo H.

    Sci Rep.   8 ( 1 )   5435   2018.4

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1038/s41598-018-23810-8

    PubMed

  • Copy number elevation of 22q11.2 genes arrests the developmental maturation of working memory capacity and adult hippocampal neurogenesis.

    Boku, S., Izumi, T., Abe, S., Takahashi, T., Nishi, A., Nomaru, H., Naka, Y., Kang, G., Nagashima, M., Hishimoto, A., Enomoto, S., Duran-Torres, G., Tanigaki, K., Zhang, J., Ye, K., Kato, S., Männistö, P.T., Kobayashi, K., and Hiroi, N.

    Mol Psychiatry   23 ( 4 )   985 - 992   2018.4

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1038/mp.2017.158

    PubMed

  • In Vivo Spiking Dynamics of Intra- and Extratelencephalic Projection Neurons in Rat Motor Cortex.

    Saiki, A., Sakai, Y., Fukabori, R., Soma, S., Yoshida, J., Yawo, H., Kobayashi, K., Kimura, M., and Isomura, Y.

    Cerebral Cortex   28 ( 3 )   1024 - 1038   2018.3

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1093/cercor/bhx012

    PubMed

  • Action Selection and Flexible Switching Controlled by the Intralaminar Thalamic Neurons.

    Kato S, Fukabori R, Nishizawa K, Okada K, Yoshioka N, Sugawara M, Maejima Y, Shimomura K, Okamoto M, Eifuku S, Kobayashi K

    Cell reports   22 ( 9 )   2370 - 2382   2018.2

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.celrep.2018.02.016

    PubMed

  • Anatomical Evidence for a Direct Projection from Purkinje Cells in the Mouse Cerebellar Vermis to Medial Parabrachial Nucleus.

    Hashimoto M, Yamanaka A, Kato S, Tanifuji M, Kobayashi K, Yaginuma H

    Frontiers in neural circuits   12   6   2018.2( ISSN:16625110

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3389/fncir.2018.00006

    PubMed

  • In Vivo Observation of Structural Changes in Neocortical Catecholaminergic Projections in Response to Drugs of Abuse.

    Morimoto, M., Kobayashi, K., and Okabe, S

    eNeuro   5 ( 1 )   2018.2

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1523/ENEURO.0071-17.2018

    PubMed

  • Segregated Excitatory-Inhibitory Recurrent Subnetworks in Layer 5 of the Rat Frontal Cortex.

    Morishima, M., Kobayashi, K., Kato, S., Kobayashi, K., and Yasuo Kawaguchi.

    Cereb Cortex   27 ( 12 )   5846 - 5857   2017.12

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1093/cercor/bhx276

    PubMed

  • Light/dark phase-dependent spontaneous activity is maintained in dopamine-deficient mice.

    Fujita, M., Hagino, Y., Takeda, T., Kasai, S., Tanaka, M., Takamatsu, Y., Kobayashi, K., and Ikeda, K.

    Mol Brain.   10 ( 1 )   49   2017.10

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1186/s13041-017-0329-4

    PubMed

  • Neuronal cytoskeletal gene dysregulation and mechanical hypersensitivity in a rat model of Rett syndrome.

    Bhattacherjee, A., Mu, Y., Winte, M., Knapp, J.R., Eggiman, A. Gunewardena, S., Kobayashi, K., Kato, S., Krizsan-Agbas, D., and Smith, P.

    Proc Natl Acad Sci U S A.   114 ( 33 )   E6952 - E6961   2017.8

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1073/pnas.1618210114

    PubMed

  • Optimisation of murine organotypic slice culture preparation for a novel sagittal-frontal co-culture system.

    Joost, S., Kobayashi, K., Wree, A., and Haas, S.J.

    J Neurosci Methods.   285   49 - 57   2017.7

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.jneumeth.2017.05.003

    PubMed

  • The use of an optimized chimeric envelope glycoprotein enhances the efficiency of retrograde gene transfer of a pseudotyped lentiviral vector in the primate brain.

    Tanabe, S., Inoue, K.-I., Tsuge, H., Uezono, S., Nagaya, K., Fijiwara, M., Kato, S., Kobayashi, K., and Takada, M.

    Neurosci Res.   120   45 - 52   2017.7

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.neures.2017.02.007

  • Using a novel PV-Cre rat model to characterize pallidonigral cells and their terminations.

    Oh YM, Karube F, Takahashi S, Kobayashi K, Takada 3, Uchigashima M, Watanabe M, Nishizawa K, Kobayashi K, Fujiyama F

    Brain Struct Funct.   222 ( 5 )   2359 - 2378   2017.7

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s00429-016-1346-2

    PubMed

  • Spatial distribution of synapses on tyrosine hydroxylase-expressing juxtaglomerular cells in the mouse olfactory glomerulus.

    Kiyokage, E., Kobayashi, K, and Toida, K

    Journal of Comparative Neurology   525 ( 5 )   1059 - 1074   2017.4

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1002/cne.24147

  • Dopamine D1 receptor immunoreactivity on fine processes of GFAP-positive astrocytes in the substantia nigra pars reticulate of adult mouse.

    Nagatomo, K., Suga, S., Saitoh, M., Kogawa, M., Kobayashi, K., Yamamoto, Y., and Yamada, K.

    Front. Neuroanat   11 ( 3 )   2017.2

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3389/fnana.2017.00003

    PubMed

  • Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ.

    Matsuda, T., Hiyama, T.Y., Nimura, F., Matsusaka, T., Fukamizu, A., Kobayashi, K., Kobayashi, K., and Noda, M.

    Nature Neuroscience   20 ( 2 )   230 - 241   2017.2

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1038/nm.4463.

  • Contribution of propriospinal neurons to recovery of hand dexterity after corticospinal tract lesions in monkeys.

    Tohyama, T., Kinoshita, M., Kobayashi, K., Isa, K., Watanabe, D., Kobayashi, K., Liu, M., and Isa, T.

    Proceedings of the National Academy of Sciences of the United States of America   114 ( 3 )   604 - 609   2017.1

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1073/pnas.1610787114.

    PubMed

  • Involvement of mesolimbic dopaminergic network in neuropathic pain relief by Treadmill exercise: A study for specific neural control with Gi-DREADD in mice.

    Kenta Wakaizumi, Takashige Kondo, Yusuke Hamada, Michiko Narita, Rui Kawabe, Hiroki Narita, Moe Watanabe, Shigeki Kato, Emiko Senba, Kazuto Kobayashi, Naoko Kuzumaki, Akihiro Yamanaka, Hiroshi Morisaki, and Minoru Narita

    Mol. Pain 12   12   pii:1744806916681567   2016.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1177/1744806916681567

    PubMed

  • Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders.

    Yamada, K., Takahashi, S., Karube, F., Fujiyama, F., Kobayashi, K., Nishi, A., and Momiyama, T.

    The Journal of Physiological Sciences   66 ( 6 )   435 - 446   2016.11

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s12576-016-0445-4

  • Survival of corticostriatal neurons by small GTPase Rho.

    131. Kobayashi, K. Sano, H., Kato, S., Kuroda, K., Nakamuta, S., Isa, T., Nambu, A., Kaibuchi, K., and Kobayashi, K.

    Neurosci. Lett.   630 ( 1 )   45 - 52   2016.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1016/j.neulet.2016.07.020

    PubMed

  • Ionic basis for membrane potential resonance in neurons of the inferior olive.

    Matsumoto-Makidono, Y., Nakayama, H., Yamasaki, M., Miyazaki, T., Kobayashi, K., Watanabe, M., Kano, M., Sakimura, K. and Hashimoto, K.

    Cell Rep.   16   994 - 1004   2016.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures.

    Uchigashima, M., Ohtsuka, T., Kobayashi, K., and Watanabe, M.

    Proceedings of the National Academy of Sciences of the United States of America   113 ( 15 )   4206 - 4211   2016.4

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1073/pnas.1514074113.

  • Neuronal circuits and physiological roles of the basal ganglia in terms of transmitters, receptors and related disorders.

    Yamada, K., Takahashi, S., Karube, F., Fujiyama, F., Kobayashi, K., Nishi, A., and Momiyama, T.

    J. Physiol.. Sci.   2016.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

    PubMed

  • Phosphoproteomics of the dopamine pathway enables discovery of Rap1 activation as reward signal in vivo.

    Nagai, T., Nakamuta, S., Kuroda, K., Nakauchi, S., Nishioka, T., Takano, T., Zhang, X., Tsuboi, D., Funahashi, Y., Nakano, T., Yoshimoto, J., Kobayashi, K., Uchigashima, M., Watanabe, M., Miura, M., Nishi, A., Kobayashi, K., Yamada, K., Amano, M. and Kaibuchi, K.

    Neuron   89 ( 3 )   550 - 565   2016.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1016/j.neuron.2015.12.019

    PubMed

  • Causal link between the cortico-rubral pathway and functional recovery through forced impaired limb use in rats with stroke.

    Ishida, A., Isa, K., Umeda, T., Kobayashi, K., Kobayashi, K., Hida, H., and Isa, T.

    J. Neurosci.   36 ( 2 )   455 - 467   2016.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1523/JNEUROSCI.2399-15.2016

    PubMed

  • Altering entry site preference of lentiviral vectors into neuronal cells by pseudotyping with envelope glycoproteins.

    Kobayashi, K., Kato, S., Inoue, K., Takada, M., and Kobayashi, K.

    Methods Mol. Biol. (Gene Therapy of Neurological Disorders; ed. Manfredsson, F.)   1382   175 - 186   2016

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1007/978-1-4939-3271-9_12

    PubMed

  • Differential contribution of Ih to the integration of excitatory synaptic inputs in substantia nigra pars compacta and ventral tegmental area dopaminergic neurons.

    Masi, A., Narducci, R., Resta, F., Carbone, C., Kobayashi, K., and Mannaioni, G.

    Eur. J. Neurosci.   42 ( 9 )   2699 - 2706   2015.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.111/ejn.13066

    PubMed

  • Differential roles of the nucleus accumbens shell neurons containing dopamine D1 and D2 receptors in behavioral sensitization.

    Kai, N., Nishizawa, K., Ueda, S., and Kobayashi, K.

    J. Neurochem.   135   1232 - 1241   2015.10

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1111/jnc.13380

    PubMed

  • Rho-kinase inhibition during early cardiac development causes arrhythmogenic right ventricular cardiomyopathy in mice. Arterioscler.

    Ellawindy, A., Satoh, K., Sunamura, S., Kikuchi, N., Suzuki, K., Minami, T., Ikeda, S., Tanaka, S., Shimizu, T., Enkjargal, B., Miyata, S., Taguchi, Y., Handoh, T., Kobayashi, K., Kobayashi, K., Nakayama, K., Miura, M., and Shimokawa, H.

    Thromb. Vasc Biol.   35 ( 10 )   2172 - 2184   2015.10

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1161/ATVBAHA.115.305872

    PubMed

  • Distinct roles of basal forebrain cholinergic neurons in spatial and object recognition memory.

    Okada, K, Nishizawa, K., Kobayashi, T., Sakata, S., and Kobayashi, K. (2015)

    Sci. Rep.   5   13158   2015.8

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1038/srep13158

    PubMed

  • Double virus vector infection to the prefrontal network of the macaque brain.

    Oguchi, M., Okajima, M., Tanaka, S., Koizumi, M., Kikusui, T., Ichihara, N., Kato, S., Kobayashi, K., and Sakagami, M.

    PLoS One   10 ( 7 )   e0132825   2015.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1371/journal.pone.013825.

    PubMed

  • An avian sarcoma leukosis virus receptor-envelope system for simultaneous dissociation of multiple neural circuits in mammalian brain.

    Matsuyama, M., Ohashi, Y., Tsubota, T., Yaguchi, M., Kato, S., Kobayashi, K., and Miyashita, Y.

    Proc. Natl. Acad. Sci. USA   112 ( 22 )   E2947-E2956   2015.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Avian sarcoma leukosis virus receptor-envelope system for simultaneous dissection of multiple neural circuits in mammalian brain.

    Matsuyama M, Ohashi Y, Tsubota T, Yaguchi M, Kato S, Kobayashi K, Miyashita Y

    Proceedings of the National Academy of Sciences of the United States of America   112 ( 22 )   E2947 - 56   2015.6( ISSN:0027-8424

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1073/pnas.1423963112

    PubMed

  • Involvement of cholinergic system in hyperactivity in dopamine-deficient mice.

    Hagino, Y., Kasai, S., Fujita, M., Setogawa, S., Yamaura, H., Yanagihara, D., Hashimoto, M., Kobayashi, K., Meltzer, H.Y., and Ikeda, K.

    Neuropsychopharmacology   40   1141 - 1150   2015.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • 遺伝子改変技術による脳機能と病態に関する神経ネットワークの解明

    小林 和人

    福島医学雑誌   65 ( 3 )   79 - 93   2015

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • 大脳基底核による運動制御と病態生理、

    佐野裕美、小林和人、南部篤

    分子脳科学、化学同人(三品昌美編)   pp. 44-55 (total 291 pages)   2015

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • RHOA inactivation enhances Wnt signaling and promotes colorectal cancer.

    Rodrigues, P., Macaya, I., Bazzocco, S., Mazzolini, R., Andretta, E., Dopeso, H., Mateo-Lozano, S., Bilic, J., Cartón-García, F., Nieto, R., Suárez-López, L., Afonso, E., Landolfi, S., Hernandez-Losa, J., Kobayashi, K., y Cajal, S.R., Tabernero, J., Tebbutt, N.C., Mariadason, J.M., Schwartz Jr, S., and Arango, D.

    Nat. Commun.   5   5458   2014.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1038/ncomms6458

    PubMed

  • Transcriptional and structural plasticity of tyrosine hydroxylase expressing neurons in both striatum and nucleus accumbens following dopaminergic denervation.

    Depboylu, C., Klietz, M., Maurer, L., Oertel, W.H., Kobayashi, K., Weihe, E., Höglinger, G.U., and Schäfer, M. K.

    J. Chem. Neuroanat. : (Nov) doi   61/62   169 - 175   2014.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1016/j.jchemneu.2014.10.003

    PubMed

  • Simultaneous visualization of extrinsic and intrinsic axon collaterals in Golgi-like detail for mouse corticothalamic and corticocortical cells: a double viral infection method.

    Watakabe, A., Takaji, M., Kato, S., Kobayashi, K., Mizukami, H., Ozawa, K., Ohsawa, S., Matsui, R., Watanabe, D., and Yamamori, T.

    Front. Neural Circuits   8   110   2014.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.3389/fncir.2014.00110

    PubMed

  • Crucial role of rho-kinase in pressure overload-induced right ventricular hypertrophy and dysfunction in mice.

    Ikeda, S., Satoh, K., Kikuchi, N., Miyata, S., Suzuki, K., Omura, J., Shimizu, T., Kobayashi, K., Kobayashi, K., Fukumoto, Y., Sakata, Y., and Shimokawa, H.

    Arterioscler. Thromb. Vasc Biol.   34 ( 6 )   1260 - 1271   2014.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1161/ATVBAHA.114.303320

  • Enhanced flexibility of place discrimination learning by targeting of striatal cholinergic interneurons.

    Okada, K., Nishizawa, K., Fukabori, R., Kai, N., Shiota, A., Ueda, S., Tsutsui, Y., Sakata, S., Matsushita, N., and Kobayashi, K.

    Nat. Commun.   5   3778   2014.5

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1038/ncomms4778

    PubMed

  • Lesions of the nucleus accumbens core modulate development of matching behavior.

    Kai, N., Tsutsui, Y., and Kobayashi, K.

    BMC Neurosci.   15   55   2014.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1186/1471-2202-15-55

  • Improved transduction efficiency of a lentiviral vector for neuron-specific retrograde gene transfer by optimizing the junction of fusion envelope glycoprotein.

    Kato, S., Kobayashi, K., and Kobayashi, K.

    J. Neurosci. Methods   227   151 - 158   2014.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1016/j.jneumeth.2014.02.015

    PubMed

  • Methylglyoxal (MG) and cerebro-renal interaction: Does long-term orally-administered MG cause cognitive impairment in normal Sprague-Dawley rats?

    Watanabe, K., Okada, K., Fukabori, R., Hayashi, Y., Asahi, K., Terawaki, H., Kobayashi, K., Watanabe, T., and Nakayama, M.

    Toxins   6 ( 1 )   254 - 269   2014.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.3390/toxins6010254

  • Molecular mechanisms that drive estradiol-dependent burst firing of Kiss1 neurons in the rostral periventricular preoptic area.

    Zhang, C., Tonsfeldt, K.J., Qiu, J., Bosch, M.A., Kobayashi, K., Steiner, R.A., Kelly, M.J. and Rønnekleiv, O.K.

    Am. J. Physiol. Endocrinol. Metab.   305 ( 11 )   E1384-1397   2013.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

    PubMed

  • Viral vector-mediated selective and reversible blockade of the pathway for visual orienting in mice.

    Sooksawate, T., Isa, K., Matsui, R., Kato, S., Kinoshita, M., Kobayashi, K., Watanabe, D., Kobayashi, K., and Isa, T.

    Front. Neural Circuits   7   162   2013.10

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.3389/fncir.2013.00162

    PubMed

  • Highly efficient retrograde gene transfer into motor neurons by lentiviral vector pseudotyped with fusion glycoprotein.

    Hirano, M., Kato, S., Kobayashi, K., Okada, T., Yaginuma, H., and Kobayashi, K.

    PLoS One   8 ( 9 )   e75896   2013.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1371/journal.pone.0075896

    PubMed

  • Chronic alterations in monoaminergic cells in locus coeruleus in orexin neuron-ablated narcoleptic mice.

    Tsujino, N., Tsunematsu, T., Uchigashima, M., Konno, K., Yamanaka, A., Kobayashi, K., Watanabe, M., Koyama, Y., and Sakurai, T.

    PLoS One   8 ( 7 )   e70012   2013.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1371/journal.pone.0070012

    PubMed

  • Role of convergent activation of glutamatergic and dopaminergic systems in the nucleus accumbens in the development of methamphetamine psychosis and dependence.

    Miyazaki, M., Noda, Y., Mouri, A., Kobayashi, K., Mishina, M., Nabeshima, T., Yamada, K.

    Int. J. Neuropsychopharmacol.   16 ( 6 )   1341 - 1350   2013.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1017/S1461145712001356

    PubMed

  • Protocadherin 17 regulates presynaptic assembly in topographic cortico-basal ganglia circuits.

    Hoshina, N., Tanimura, A., Yamasaki, M., Inoue, T., Fukabori, R., Kuroda, T., Yokoyama, K., Tezuka, T., Sagara, H., Hirano, S., Kiyonari, H., Takada, M., Kobayashi, K., Watanabe, M., Kano, M., Nakazawa, T. and Yamamoto, T.

    Neuron   78 ( 5 )   839 - 854   2013.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1016/j.neuron.2013.03.031

    PubMed

  • Signals through the striatopallidal indirect pathway stop movements by phasic excitation in the substantia nigra.

    Sano, H., Chiken, S., Hikida, T., Kobayashi, K., and Nambu, A.

    J. Neurosci.   33 ( 17 )   7583 - 7594   2013.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

    PubMed

  • Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures.

    Uchigashima, M., Ohtsuka, T., Kobayashi, K., and Watanabe, M.

    Proc. Natl. Acad. Sci. USA   113 ( 15 )   4206 - 4211   2013.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1073/pnas.1514074113

    PubMed

  • Transcranial direct-current stimulation increases extracellular dopamine levels in the rat striatum.

    Tanaka, T., Takano, Y., Tanaka, S., Hironaka, N., Kobayashi, K., Watanabe, K., Honda, M.

    Front. Syst. Neurosci.   7   6   2013.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.3389/fnsys.2013.00006

    PubMed

  • Dissecting circuit mechanisms by genetic manipulation of specific neural pathways.

    Kato, S., Kobayashi, K., and Kobayashi, K

    Rev. Neurosci.   24 ( 1 )   1 - 8   2013.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1515/revneuro-2012-0043

    PubMed

  • Striatal indirect pathway contributes to selection accuracy of learned motor actions.

    Nishizawa, K., Fukabori, R., Okada, K., Kai, N., Uchigashima, M., Watanabe, M., Shiota, A., Ueda, S., Tsutsui, Y., and Kobayashi, K.

    J. Neurosci.   32 ( 39 )   13421 - 13432   2012.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Functional properties of dopamine neurons and co-expression of vasoactive-intestinal-polypeptide in the dorsal raphe nucleus and ventro-lateral periaqueductal grey.

    Dougalis, A.G., Matthews, GAC, Bishop, MW, Brischoux, F., Kobayashi, K., and Ungless, M.A.

    Eur. J. Neurosci.   36 ( 10 )   3322 - 3332   2012.8

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1111/j.1460-9568.2012.08255.x.

    PubMed

  • Genetic dissection of the circuit for hand dexterity in primates.

    Kinoshita, M., Matsui, R., Kato, S., Hasegawa, T., Kasahara, H., Isa, K., Watakabe, A., Yamamori, T., Nishimura, Y., Alstermark, B., Watanabe, D., Kobayashi, K., and Isa, T.

    Nature   487 ( 7406 )   235 - 238   2012.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Immunotoxin-mediated tract targeting in the primate brain: selective elimination of the cortico-subthalamic “hyperdirect” pathway.

    Inoue, K., Koketsu, D., Kato, S., Kobayashi, K., Nambu, A., and Takada, M.

    PLoS One   7 ( 6 )   e39149   2012.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Striatal direct pathway modulates response time in execution of visual discrimination.

    Fukabori, R., Nishizawa, K., Okada, K., Kai, N., Kobayashi, K., Uchigashima, M., Watanabe, M., Tsutsui, Y., and Kobayashi, K.

    Eur. J. Neurosci.   35 ( 5 )   784 - 797   2012.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Visualization of the cortical projection neurons by retrograde TET-Off lentiviral vector.

    Watakabe, A., Kato, S., Kobayashi, K., Takaji, M., Nakagami, Y., Sadakane, O., Ohtsuka, M., Hioki, H., Kaneko, T., Okuno, H., Kawashima, T., Bito, H., Kitamura Y., and Yamamori, T.

    PLoS One   7   e46157   2012

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Neuron-specific gene transfer through retrograde transport of lentiviral vector pseudotyped with a novel type of fusion envelope glycoprotein.

    Kato, S., Kuramochi, M., Takasumi, K., Kobayashi, K., Inoue, K., Takahara, D., Hitoshi, S., Ikekana, K., Shimada, T., Takada, M., and Kobayashi, K.

    Hum. Gene Ther.   22 ( 12 )   1511 - 1523   2011.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Selective neural pathway targeting reveals key roles of thalamostriatal projection in the control of visual discrimination.

    Kato, S., Kuramochi, M., Kobayashi, K., Fukabori, R., Okada, K., Uchigashima M., Watanabe, M., Tsutsui, Y., and Kobayashi, K.

    J. Neurosci.   31 ( 47 )   17169 - 17179   2011.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Postnatal development of tyrosine hydroxylase mRNA-expressing neurons in mouse neostriatum.

    Masuda, M., Miura, M., Inoue, R., Imanishi, M., Saino-Saito, S., Takada, M., Kobayashi, K., and Aosaki, T. (2011)

    Eur. J. Neurosci.   34 ( 9 )   1355 - 1367   2011.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Dynamic expression of cadherins modulates vocal plasticity in a songbird.

    Matsunaga, E., Suzuki, K., Kato, S., Kurotani, T., Kobayashi, K., and Okanoya, K.

    PLoS One   6 ( 9 )   e25272   2011.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • p38 MAPKs regulate the expression of genes in the dopamine synthesis pathway through phosphorylation of NR4A nuclear receptors.

    Sekine, Y., Takagahara, S., Hatanaka, R., Watanabe, T., Oguchi, H., Noguchi, T., Naguro, I., Kobayashi, K., Tsunoda, M., Funatsu, T., Nomura, H., Toyoda, T., Matsuki, N., Kuranaga, E., Miura, M., Takeda, K., and Ichijo, H.

    J. Cell. Sci.   124 ( 17 )   3006 - 3016   2011.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Up-regulation of dopamine D1 receptor in the hippocampus after establishment of conditioned place preference by cocaine.

    Tanaka, T., Kai, N., Kobayashi, K., Takano, Y., Hironaka, N.

    Neuropharmacology   61 ( 4 )   842 - 848   2011.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Sensory input regulates spatial and subtype-specific patterns of neuronal turnover in the adult olfactory bulb.

    Sawada, M., Kaneko, N., Wake, H., Inada, H., Kato, Y., Yanagawa, Y., Kobayashi, K., Nemoto, T., Nabekura, J. and Sawamoto, K.

    J. Neurosci.   31 ( 32 )   11587 - 11596   2011.8

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Compensation of depleted neuronal subsets by new neurons in a local area of the adult olfactory bulb.

    Koshi Murata, Maki Imai, Shigetada Nakanishi, Dai Watanabe, Ira Pastan, Kazuto Kobayashi, Tomoko Nihira, Hideki Mochizuki, Shuichi Yamada, Kensaku Mori and Masahiro Yamaguchi

    J. Neurosci.   31 ( 29 )   10540 - 10557   2011.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Targeting of locus ceruleus noradrenergic neurons expressing human interleukin-2 receptor a-subunit in transgenic mice by a recombinant immunotoxin anti-Tac(Fv)-PE38: A study for exploring noradrenergic influence upon anxiety-like and depression-like behaviors.

    Itoi, K., Sugimoto, N., Suzuki, S., Sawada, K., Das, G., Uchida, K., Fuse, T., Ohara, S., and Kobayashi, K.

    J. Neurosci.   31 ( 16 )   6132 - 6139   2011.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Glomerular Sclerosis is prevented during urinary tract obstruction due to podocyte protection.

    Matsusaka, T., Kobayashi, K., Kon, V., Qing-cheng, Pastan, I., Fogo, A.B., and Ichikawa, I.

    Am. J. Physiol. Renal Physi.   300 ( 3 )   F792-800   2011.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • AKT suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy.

    Cheng, H.-C., Kim, S.R., Oo, T., Kareva, T., Yarygina, O., Rzhetskaya, M., Wang, C., During, M., Talloczy, Z., Tanaka, K., Komatsu, M., Kobayashi, K., Okano, H., Kholodilov, N., and Burke, R.

    J. Neurosci.   31 ( 6 )   2125 - 2135   2011.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • A lentiviral strategy for highly efficient retrograde gene transfer by pseudotyping with fusion envelope glycoprotein.

    Kato, S., Kobayashi, K., Inoue, K., Kuramochi, M., Okada, T., Yaginuma, H., Morimoto, K., Shimada, T., Takada, M., and Kobayashi, K.

    Hum. Gene Ther.   22 ( 2 )   197 - 206   2011.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Rho/Rho-kinase signaling pathway controls axon patterning of a specified subpopulation of cranial motor neurons.

    Kobayashi, K., Masuda, T., Takahashi, M., Miyazaki, J., Nakagawa, M., Uchigashima, M., Watanabe, M., Yaginuma, H., Osumi, N., Kaibuchi, K., and Kobayashi, K.

    Eur. J. Neurosci.   33 ( 4 )   612 - 621   2011.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Lever pressing responses under a fixed-ratio schedule of mice with 6-hydroxydopamine-induced dopamine depletion in the nucleus accumbens.

    Tsutsui, Y., Nishizawa, K., Kai, N., and Kobayashi, K.

    Behav. Brain Res.   217 ( 1 )   60 - 66   2011.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Evaluation of Pax6 mutant rat as a model for autism.

    Umeda, T., Takashima, N., Nakagawa, R., Maekawa, M., Ikegami, S., Yoshikawa, T., Kobayashi, K., Okanoya, K., Inokuchi, K., and Osumi, N.

    PLoS One   5 ( 12 )   e15500   2010.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Synaptic input of ON-bipolar cells onto the dopaminergic neurons of the mouse retina.

    Contini, M., Lin, B., Kobayashi, K., Okano, H., Masland, R.H., and Raviola, E.

    J. Comp. Neurol.   518 ( 11 )   2035 - 2050   2010.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Effects of age, presence of neurons and endothelin-3 on the ability of enteric neuron precursors to colonize recipient gut.

    Hotta, R., Anderson, R.B., Kobayashi, K., Newgreen, D.F. and Young, H.M.

    Neurogastroenterol. Motil.   22 ( 3 )   331-e86   2010.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • 道具的学習と行動制御を研究するモデル実験動物

    小林和人、深堀良二、甲斐信行、岡田佳奈、小林とも子

    生体の科学   61 ( 1 )   47 - 52   2010.1

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • Molecular identity of periglomerular and short axon cells.

    Kiyokage E., Pan Y., Shao, Z., Kobayashi, K., Szabo, Y., Yanagawa, Y., Obata, K., Okano, H., Toida, K., Puche, A.C., and Shipley. M.T.

    J. Neurosci.   30 ( 3 )   1185 - 1196   2010.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • ドパミンによるドパミンニューロンの選択的障害

    小林憲太、小林和人

    Clinical Neuroscience   28 ( 1 )   8 - 9   2010.1

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • Unexpected expression of α- and β-globin in mesencephalic dopaminergic neurons and glial cells.

    Biagioli, M., Pinto, M., Cesselli, D., Zaninello, M., Lazarevic, D., Simone, R., Vlachouli, C., Plessy, C., Bertin, N., Beltrami, A., Kobayashi, K., Gallo, V., Ferrer, I., Santoro, C., Rivella, S., Beltrami, C.A., Carninci, P., Raviola, E., and Gustincich, S.

    Proc. Natl. Acad. Sci. USA   106 ( 36 )   15446 - 15451   2009.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons.

    Mosharov EV, Larsen KE, Kanter E, Phillips KA, Wilson K, Schmitz Y, Krantz DE, Kobayashi K, Edwards RH, and Sulzer D.

    Neuron   62 ( 2 )   218 - 229   2009.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • イムノトキシン細胞標的法を用いた直接路・間接路の機能解析

    深堀良二、小林和人 (2009)

    Brain and Nerve   61 ( 4 )   412 - 418   2009.4

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • Identification of an activator protein-1-like Sequence as the glucocorticoid response element in the rat tyrosine hydroxylase gene.

    Sheela Rani, C.S., Elango, N., Wang, S.-S., Kobayashi, K. and Strong, R.

    Mol. Pharmacol.   75 ( 3 )   589 - 598   2009.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Laminin peptide YIGSR and its receptor regulate sensory axonal response to the chemoattractive guidance cue in the chick embryo.

    Masuda, T., Sakuma, C., Kobayashi, K., Kikuchi, K., Soda, E., Shiga, T., Kobayashi, K., and Yaginuma, H.

    J. Neurosci. Res.   87 ( 2 )   353 - 359   2009.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • The migratory behavior of immature enteric neurons.

    Hao, M., Anderson, R.B., Kobayashi, K., Whitington, P.M., and Young, H.M.

    Dev. Neurobiol.   69 ( 1 )   22 - 35   2009.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.

    Masuda, T., Kai, N., Sakuma, C., Kobayashi, K., Koga, H., Yaginuma, H.

    Brain Res.   1249 ( 1 )   61 - 67   2009.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Ephrin-A5 regulates the formation of the ascending midbrain dopaminergic pathways.

    Cooper, M.A., Kobayashi, K., and Zhou, R.

    Dev. Neurobiol.   69 ( 1 )   36 - 46   2009.1

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Transient silencing of synaptic transmitter release from specific neuronal types by recombinant tetanus toxin light chain fused to antibody variable region.

    Kobayashi, T., Kai, N., Kobayashi, K., Fujiwara, T., Akagawa,I., Onda, M., and Kobayashi, K.

    J. Neurosci. Methods   175 ( 1 )   125 - 132   2008.10

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Effects on NGF, NT-3, and GDNF family members on neurite outgrowth and migration from pelvic ganglia in embryonic and newborn mice.

    Stewart, A.L., Anderson, R.B., Kobayashi, K., Young, H.M.

    BMC-Dev. Biol.   8 ( 73 )   2008.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Selective loss of nigral dopamine neurons induced by overexpression of truncated human -synuclein in mice.

    Wakamatsu, M., Ishii, A., Iwata, S., Sakagami, J., Ukai, Y., Ono, M., Kanbe, D., Muramatsu, S.I., Kobayashi, K., Iwatsubo, T., and Yoshimoto, M.

    Neurobiol. Aging   29 ( 4 )   574 - 585   2008.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Non cell-autonomous roles for the planar cell polarity gene Vangl2 in development of the coronary circulation.

    Phillips, H.M., Hildreth, V., Murdoch, J.N., Kobayashi, K., Chaudhry, B. and Henderson, D.J.

    Circ. Res.   102 ( 5 )   615 - 623   2008.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Visceral afferents directly activate catecholamine neurons in the solitary tract nucleus.

    Appleyard, S.M., Marks, D., Kobayashi, K., Okano, H., Low, M.J., and Andresen, M.C.

    J. Neurosci.   27 ( 48 )   13292 - 13302   2007.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Efficient gene transfer via retrograde transport in rodent and primate brains using a human immunodeficiency virus type 1-based vector pseudotyped with rabies virus glycoprotein.

    Kato, S., Inoue, K., Kobayashi, K., Yasoshima, Y., Miyachi, S., Inoue, S., Hanawa, H., Shimada, T., Takada, M., and Kobayashi, K.

    Human Gene Ther.   18 ( 11 )   1141 - 1152   2007.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Guidance cues from the embryonic dorsal spinal cord chemoattract dorsal root ganglion axons.

    Masuda, T., Sakuma C., Taniguchi, M., Kobayashi, K., Kobayashi, K., Shiga, T., and Yaginuma, H.

    Neuroreport   18 ( 16 )   1645 - 1649   2007.10

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Compartment-specific modulation of GABAergic synaptic transmission by -opioid receptor in the mouse striatum with green fluorescent protein-expressing dopamine islands.

    Miura, M., Saino-Saito, S., Masuda, M., Kobayashi, K., and Aosaki, T.

    J. Neurosci.   27 ( 36 )   9721 - 9728   2007.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Controlled cell targeting system to study the brain neural circuitry.

    Kobayashi, K.

    Neurosci. Res.   58 ( 2 )   118 - 123   2007.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Controlled cell targeting system to study the brain neural circuitry.

    Kobayashi, K.

    Neurosci. Res.   58 ( 2 )   118 - 123   2007.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Accumulation of phosphorylated a-synuclein dopaminergic neurons of transgenic mice that express human -synuclein.

    Wakamatsu, M., Ishii, A., Ukai, Y., Sakagami, J., Iwata, S., Ono, M., Matsumoto, K., Nakamura, A., Tada, N., Kobayashi, K., Iwatsubo, T., and Yoshimoto, M.

    J. Neurosci. Res.   85   1819 - 1825   2007.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • ER81 and CaMKIV identify anatomically and phenotypically defined subsets of mouse olfactory bulb interneurons.

    Saino-Saito, S., Cave, J.W., Akiba, Y., Sasaki, H., Goto, K., Kobayashi, K., Berlin, R.A., and Baker, H.

    J. Comp. Neurol.   502 ( 4 )   485 - 496   2007.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • ニューロンネットワーク解析の新技術:組換え体イムノトキシンを利用した細胞標的法

    小林 和人

    化学と生物   45 ( 1 )   16 - 20   2007.1

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • ニューロンネットワーク解析の新技術:組換え体イムノトキシンを利用した細胞標的法

    小林 和人

    化学と生物   45 ( 1 )   16 - 20   2007.1

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • Selective loss of nigral dopamine neurons induced by overexpression of truncated human a-synuclein in mice.

    Wakamatsu, M., Ishii, A., Iwata, S., Sakagami, J., Ukai, Y., Ono, M., Kanbe, D., Muramatsu, S.I., Kobayashi, K., Iwatsubo, T., and Yoshimoto, M.

    Neurobiol. Aging   2006.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Bidirectional reguation of dopamine D2 and neurotensin NTS1 receptors in dopamine neurons.

    Jomphe, C., Lemelin, P.-L., Okano, H., Kobayashi, K., and Trudeau, L.-E.

    Eur. J. Neurosci.   24 ( 10 )   2789 - 2800   2006.11

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Decline of endogenous dopamine release in parkin-deficient mice revealed by ex vivo autoradiography.

    Sato, S., Chiba, T., Nishiyama, S., Kakiuchi, T., Tsukada, H., Hatano, T., Fukuda, T., Yasoshima, Y., Kai, N., Kobayashi, K., Mizuno, Y., Tanaka, K., and Hattori, N.

    J. Neurosci. Res.   84   1350 - 1357   2006.8

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Dynamic temporal and cell type-specific expression of Wnt signaling components in the developing midbrain.

    Rawal, N., Castelo-Branco, G., Sousa, K. M., Kobayashi, K., Okano, H., and Arenas, E.

    Exp. Cell Res.   312 ( 9 )   1626 - 1636   2006.5

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Granulocyte-colony stimulating factor is neuroprotective in a model of Parkinson's disease.

    Meuer, K., Teismann, P., Peters, K., Göricke, B., Lingor, P., Schlachetzki, J., Kobayashi, K., Dietz, G. P.H., Schulz, J.B., Bähr, M., Schneider, A., and Weishaupt, J. H.

    J. Neurochem.   97 ( 3 )   675 - 686   2006.5

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Separation of m-opioid receptor desensitization and internalization: endogenous receptors in primary neuronal cultures.

    Arttamangkul, S., Torrecilla, M., Kobayashi, K., Okano, H., and Williams, J.T.

    J. Neurosci.   26 ( 15 )   4118 - 4125   2006.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Altered gene expression in the subdivisions of the amygdala of Fyn-deficient mice as revealed by laser capture microdissection and mKIAA cDNA array analysis.

    Kai, N., Iwase, K., Imai, K., Nakahira, E., Soma, M., Ohtsuka, S., Yagi, T., Kobayashi, K., Koga, H., Takiguchi, M., and Yuasa, S.

    Brain Res.   1073/1074   60 - 70   2006.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Visualization, direct isolation, and transplantation of midbrain dopaminergic neurons.

    Proc. Natl. Acad. Sci. USA   98 ( 11 )   6423 - 6428   2001

      More details

    Publishing type:Research paper (other academic)  

  • Modest Neuropsychological deficits caused by reduced noradrenaline metabolism in mice heterozygous for a mutated tyrosine hydroxylase gene

    J. Neurosci.   20 ( 6 )   2418 - 2426   2000

      More details

    Publishing type:Research paper (other academic)  

  • Autonomic neuropathy in transgenic mice cansed by immunotorin targeting of the peripheral neurons system

    J. Neurosci. Res.   51 ( 2 )   162 - 173   1998

      More details

    Publishing type:Research paper (other academic)  

  • Ablation of cerebellar Golgi cells disrupts synaptic integration involring GABA inhibition and NMDA receptor activation in motor control

    Cell   95 ( 1 )   17 - 27   1998

      More details

    Publishing type:Research paper (other academic)  

  • Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission

    J. Neurosci. Res.   54 ( 4 )   450 - 464   1998

      More details

    Publishing type:Research paper (other academic)  

  • Targeted disruption of the tyrosire hydroxylase locus results in severe catecholamine depletion and perinatal lethality in mice.

    J. Biol. Chem.   270 ( 45 )   27235 - 27243   1995

      More details

    Publishing type:Research paper (other academic)  

  • Immunotoxin-mediated conditional disruption of specific neurons in transgenic mice.

    Proc. Natl. Acad. Sci. USA   92 ( 4 )   1132 - 1136   1995

      More details

    Publishing type:Research paper (other academic)  

  • Functional and high lerel expression of human dopamine β-hydroxylase ih transgenic mice

    J. Biol. Chem.   269 ( 47 )   29725 - 29731   1994

      More details

    Publishing type:Research paper (other academic)  

  • Genetic alteration of catecholamine specificity in transgenic mice.

    Proc. Natl. Acad. Sci. USA   89 ( 5 )   1631 - 1635   1992

      More details

    Publishing type:Research paper (other academic)  

  • Tissue-specific and high-level expression of the human tyvosine hydroxylase gene in transgenic mice

    Neuron   6   583 - 594   1991

      More details

    Publishing type:Research paper (other academic)  

▼display all

Books

  • Viral Gene Therapy

    Ke Xu(Highly efficient retrograde gene transfer for genetic treatment of neurological diseases. In Viral Gene Therapy (ed. Ke Xu) Chapter 17, InTech, Rijeka (Croatia), pp.371-380 (July 21) (total page 450) ISBN: 978-953-307-539-6, Available from: http://www.intechopen.com/articles/show/title/highly-efficient-retrograde-gene-transfer-for-genetic-treatment-of-neurological-diseases)

    InTech  2011.7 

     More details

    Responsible for pages:371-380   Language:English  

    Authors name of the chapter and paper which it took charge of:Kato, S., Kobayashi, K., Kuramochi, M., Inoue, K., Takada, M., and Kobayashi, K. (2011)   Publication place:Rijeka (Croatia)  

  • The Primer on the Autonomic Nervous System, 3rd edition

    David Robertson, Italo Biaggioni, Geoffrey Burnstock, Phillip A. Low and Julian F.R. Paton(Human tyrosine hydroxylase.)

    Academic Press  2012 

     More details

    Responsible for pages:45-48   Language:English  

    Authors name of the chapter and paper which it took charge of:Kobayashi, K. and Nagatsu, T.   Publication place:London  

  • Neuromethods, Controlled Genetic Manipulations

    Alexei, M.(Functional circuitry analysis in rodents using neurotoxins/immunotoxins.)

    Humana Press Inc.  2012 

     More details

    Responsible for pages:193-205   Language:English  

    Authors name of the chapter and paper which it took charge of:Kobayashi, K., Okada, K., and Kai, N.   Publication place:New York  

  • Gene Therapy

    Francisco Martin(Vectors for highly efficient and neuron-specific retrograde gene transfer for gene therapy of neurological diseases.)

    InTech  2012 

     More details

    Language:English  

    Authors name of the chapter and paper which it took charge of:Kato, S., Kobayashi, K., Inoue, K., Takada, M., and Kobayashi, K.  

  • Gene Therapy -Tools and Potential Applications

    Francisco Martin Molina(Vectors for highly efficient and neuron-specific retrograde gene transfer for gene therapy of neurological diseases.)

    InTech  2013.2  ( ISBN:978-953-51-1014-9

     More details

    Responsible for pages:387-398   Language:English  

    Authors name of the chapter and paper which it took charge of:Kato, S., Kobayashi, K., Inoue, K., Takada, M., and Kobayashi, K.   Publication place:Rijeka (Croatia)  

Presentations

  • Enhanced gene transfer efficiency of a neuron-specific retrograde viral vector with variants of fusion glycoprotein type E into common marmoset brains

      More details

    Event date: 2019.2

  • 現代の脂質食はドパミンニューロンの過剰産生を介して嗜好食品の摂取を促す

    次世代脳若手合同シンポジウム  

      More details

    Event date: 2018.12

  • 自らのキャリア形成を振り返って

    FMUキャリアアップセミナー  

      More details

    Event date: 2018.11

  • 視床線条体路を介する行動選択と切り替えの調節

    遺伝研研究会  

      More details

    Event date: 2018.9

  • 線条体における学習依存的な神経回路シフトの解明

    第33回日本大脳基底核研究会  

      More details

    Event date: 2018.8

  • 若手研究者のための科研費研究計画書の書き方

    福島県立医科大学科研費講習会  

      More details

    Event date: 2018.8

  • Behavioral selection and switching flexibility regulated by thalamustriatal circuit

    第41回日本神経科学大会  

      More details

    Event date: 2018.7

  • Lentiviral vectors pseudotyped with FuG-E and FuG-E2 glycoprotein suitable for retrograde gene transfer into neural networks involveing cerebral cortical areas in nonhuman primates and rodents.

    第41回日本神経科学大会  

      More details

    Event date: 2018.7

  • Identification of indirect pathway neurons and dopaminergic innervation in the rat dorsomedial striatum

    第41回日本神経科学大会  

      More details

    Event date: 2018.7

  • Anatomical evidence for a direct projection from Purukinje cells in the mouse cerebellar vermis to medial parabrachial nucleus

    第41回日本神経科学大会  

      More details

    Event date: 2018.7

  • 神経回路の遺伝子操作による動物モデル研究

    第29回東北動物実験研究会  

      More details

    Event date: 2018.7

  • A Novel Chemogenetic Strategyby using Drosophila IRs.

    Seminar in Lausanne Unniversity  

      More details

    Event date: 2018.7

  • Gene expression profile of dopamine-deficient mouse brain for underlying molecular pathology in psychiatric disorders

    31st CINP2018  

      More details

    Event date: 2018.6

  • Function of subclassified corticotropin-releasing factor neurons in the hypothalamic paraventricular nucleus

    第95回日本生理学会大会  

      More details

    Event date: 2018.3

  • 行動の選択と柔軟な切り替えを媒介する視床髄板内核ニューロン

    大脳基底核機能研究会  

      More details

    Event date: 2018.3

  • 行動の選択と切り替えを媒介する神経回路ネットワーク

    奈良医大特別講演  

      More details

    Event date: 2018.3

  • 特定神経回路の機能制御を可能とする高頻度逆行性導入ウイルスベクターの開発

    京大霊長類研究所共同利用研究会  

      More details

    Event date: 2018.2

  • 背内側線条体コリン作動性介在神経細胞の行動柔軟性における双方向的制御

    先端モデル動物支援プラットフォーム成果発表会  

      More details

    Event date: 2018.1

  • Noradrenergic control of emotional memory retrieval.

    適応回路シフト国際シンポジウム  

      More details

    Event date: 2017.12

  • 経路選択的な回路操作技術の応用:行動制御機構の解明に迫る経路選択的な回路操作技術の応用:行動制御機構の解明に迫る

    生理研研究会「脳の階層的理解を目指して」  

      More details

    Event date: 2017.11

  • Differences in retrograde gene transfer efficiency and cytotoxicity between lentiviral vectors pseudotyped with FuG-E and FuG-B2 glycoprotein in rodent and primate brains.

    47th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2017.11

  • Action-specific reinforcement and update by direct- and indirect- pathway striatal projection neurons.

    47th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2017.11

  • 経路選択的な遺伝子操作技術を応用した脳機能と病態モデル研究

    愛知医科大学特別講義・研究セミナー  

      More details

    Event date: 2017.10

  • 選択的経路標的法による回路機能の解析

    平成29年度日本アルコール・薬物依存関連学会合同学術総会・第52回日本アルコール・アディクション医学会学術総会  

      More details

    Event date: 2017.9

  • Transcriptome profiling of dopamine-deficient mouse brain

    第60回日本神経化学会大会  

      More details

    Event date: 2017.9

  • 脳神経ネットワークにおける経路選択的な機能操作技術

    第4回包括的緩和医療科学学術研究会  

      More details

    Event date: 2017.8

  • 遺伝子改変技術を応用した脳神経回路機能の解析

    星薬科大学セミナー  

      More details

    Event date: 2017.8

  • Dynamic shifts of regional brain activation pattern during acquisition of an auditory discrimination task

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Dopamine D1 receptor immunoreactivity detected on fine processes of astrocytes in the adult mouse.

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Classification of corticotropin-releasing factor neurons in the hypothalamic paraventricular nucleus according to their differential neural projections

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Dopamine metabolism and coping behaveors under the tail suspenseon stress

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Activity of direct- and indirect-pathway striatal projection neurons identified by optogenetics during adaptive choice task with probabilistics reward

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • A chemogenetics approach to elucidate the role of the striatopallidal neurons in the performance of operant auditory discrimination

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Optimizing the junction of chimeric fusion glycoprotein of a lentiviral vector for higjly neuron-specific retrograde gene transfer

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • The lentiviral vector pseudotyped with FuG-E glycoprotein is more suitable, compared with the FuG-B2 type, for retrograde gene transfer into the cortical input system of primates.

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Controlling stimulus-response learning through striatal direct and indirect pathways

    40th Annual Meeting of the Society Japan Neuroscience Society  

      More details

    Event date: 2017.7

  • Functional analysis of Rho/Rho-kinase signaling pathway in corticostriatal neuron survival using a new gene delivery system

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Controlling stimulus-response learning through striatal direct and indirect pathways

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Differential involvement of direct- and indirect-pathway spiny projection neuron in action valuation and update in the dorsomedial striatum

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • AMPA density is homogeneneous across striatal synapses irrespective of cell types and input pathways

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Optogenetic analysis of neuronal network of medullary respiratory center in transgenic rats expressing channelrhodopsin in Phox2b expressing cells

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Responses in the basal ganglia induced by cortico-striatal neurons

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Using a novel PV-Cre rat model to characterize pallidal cells and their terminations

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Distinct neural mechanisms for the control of thirst and salt appetite in the subfornical organ

    第40回日本神経科学大会  

      More details

    Event date: 2017.7

  • Coordinated expression of learned motor behavior through striatofugal pathways. Advances in Japanese Behavioral Neuroscience: Diversity of Dopaminergic Regulation in the Basal Ganglia.

    40th Annual Meeting of the Society Japan Neuroscience Society  

      More details

    Event date: 2017.6

  • 皮質線条体路による意思決定の制御メカニズムの解析

    第122回日本解剖学会総会・全国学術集会  

      More details

    Event date: 2017.3

  • Behavioral role of the neural pathway connecting the cerebellum and basal ganglia functions.

    平成28年度第3回大脳基底核機能研究会  

      More details

    Event date: 2016.12

  • The lentiviral vector pseudotyped with FuG-E glycoprotein is more suitable, compared with FuG-B2, for retrograde gene transfer in the cortical input system of primate brains.

    第6回日本マーモセット研究会大会  

      More details

    Event date: 2016.12

  • Comparative study of gene transduction efficiency for retrograde gene transfer lentiviral vector with novel fusion envelope glycoproteins.

    46th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2016.11

  • Dorsal striatal indirect pathway modulates the response selection accuracy in performance of an auditory conditional discrimination task.

    Dopamine 2016  

      More details

    Event date: 2016.9

  • Comparison of the efficiency of retrograde gene transfer between lentiviral vectors pseudotyped with FuG-E and FuG-B2 glycoprotein in primate brains: Cortical input system

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • The role of cerebellar projections to the centrolateral thalamic nucleus in motor and cognitive functions

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Elucidating thr Function of the Prefronto-striatal Circuit of the Macaque Brain Using the Double Virus Vector Infection

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Activity of dopamine D2 receptor-expressing striatal neurons during decision-making task

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Use of an optimized chimeric envelope glycoprotein for enhancement of the efficiency of retrogarade gene transfer of a pseudotyped lentiviral vector in the primate brain

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Comparison of the efficiency of retrograde gene transfer between lentiviral vectors pseudotyped with FuG-E and FuG-B2 glycoprotein in primate brains: Striatal input system

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Functional analysis of Rho GTPase signaling in corticostriatal neurons usinf a dual viral vector system

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Contribution of propriospinal neurons to recovery of hand dexterity after the corticospinal tract lesion in monkeys

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Subtype-selective Gene Expression System for Cotricostriaral Neurons: Approach from Double Viral Vector Infection.

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Cortical spike ensembles of two distinct types of pyramidal neurons and fast-spiking interneurons

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • Distinct role of cholinergic neuronal groups in basal forebrain on the spatial/object recognition memory

    第39回日本神経科学大会  

      More details

    Event date: 2016.7

  • ウイルスベクター二重感染法による皮質線条体ニューロンのサブタイプ選択的な遺伝子導入法の開発

    第121回日本解剖学会  

      More details

    Event date: 2016.3

  • 行動感作における側坐核シェルのドパミンD1受容体とD2受容体含有細胞の役割の違い

    第26回マイクロダイアリシス研究会  

      More details

    Event date: 2015.12

  • 前脳基底部コリン作動系が再認記憶メカニズムに果たす役割

    包括脳冬のシンポジウム  

      More details

    Event date: 2015.12

  • 求心性神経の感知応答が見えるラットの開発

    包括脳冬のシンポジウム  

      More details

    Event date: 2015.12

  • 脳神経回路における経路選択的な機能操作技術

    第58回日本甲状腺学会基礎甲状腺学セミナー  

      More details

    Event date: 2015.11

  • Thalamostriatal system controls selection and flexibility of motor actions.

    45th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2015.10

  • Cortically induced responses in the basal ganglia thurough the cortico-striatal neurons.

    45th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2015.10

  • Dorsomedial and dorsolateral striatum have important roles in distinct learning phase of conditional discrimination.

    45th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2015.10

  • "Multi-Linc"-an optogenetic/electrophysiological method to reveal information flows among multiple brain areas.

    45th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2015.10

  • Survival of corticostriatal neurons by rho gtpase signaling pathway.

    45th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2015.10

  • Novel transgenic animals for tracing and optogenetics - Flame rats and bistable ChR receptor rats-.

    45th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2015.10

  • 大脳基底核は何をしているのか?基礎から病態まで

    第9回パーキンソン病・運動障害疾患コングレス  

      More details

    Event date: 2015.10

  • 環境刺激に適応する大脳基底核回路のメカニズム

    第45回日本神経精神薬理学会  

      More details

    Event date: 2015.9

  • Selective elimination of basal ganglia pathways in animal models

    16th Biennial Meeting of the Spanish Society for Neurosciences (SENC),  

      More details

    Event date: 2015.9

  • Differential roles of dopamine D1 and D2 receptor-containing neurons of the nucleus accumbens shell in behavioral sensitization

      More details

    Event date: 2015.9

  • 経路選択的な神経回路操作技術

    研究戦略ワークショップStrategy for Neuroscience 2015  

      More details

    Event date: 2015.9

  • 刺激弁別の学習過程における線条体領域の機能シフト

    2015年度第1回大脳基底核機能研究会  

      More details

    Event date: 2015.5

  • 線条体コリン作動性介在ニューロンを介する行動柔軟性の制御

    解剖学会・生理学会合同大会2015  

      More details

    Event date: 2015.3

  • ウィルスベクターを用いた神経回路改変技術による霊長類脳機能の研究

    平成26年度京都大学霊長類研究所共同利用研究会  

      More details

    Event date: 2015.3

  • 行動適応と神経回路の機能シフト

    浜松医科大学セミナー  

      More details

    Event date: 2015.3

  • Studying Neural Circuit Mechanism by Using Transgenic Rat Technology,

    5th Brain Research Institute International Symposium 2015  

      More details

    Event date: 2015.3

  • 遺伝子改変技術による脳機能と病態に関与する神経ネットワークの解明

    平成26年度福島医学会  

      More details

    Event date: 2015.1

  • Application of Pathway-Specific Neural Circuit Manipulation for Functional Study of Marmoset Brain

      More details

    Event date: 2015.1

  • 行動選択における視床線条体路の役割

    生理学研究所研究会「行動システム脳科学の新展開」  

      More details

    Event date: 2015.1

  • 学習による神経回路のシフト

    第25回マイクロダイアリシス研究会  

      More details

    Event date: 2014.12

  • Neural network that mediates selection and flexibility of behaviors

      More details

    Event date: 2014.11

  • 線条体コリン作動性介在細胞による行動切り替えの調節

    第21回ファーマサイエンスファーラム「生体機能解析から創薬を科学する」  

      More details

    Event date: 2014.10

  • Dorsal striatal indirect pathway regulates the response selection accuracy in auditory conditional discrimination.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Inhibitory role of cholinergic interneurons in the dorsomedial striatum via muscarinic M4 receptors on reversal and extinction learning.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Over-expression of Tbx1 or COMT in the mouse hippocampus partially recapitulates behavioral phenotypes of 22q11.2 duplication.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Improvement of gene transduction efficiency for neuron-specific retrograde gene transfer lentiviral vector with a novel function envelope glycoprotein.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Dissecting multiple neuronal pathways in mammalian brain using Avian sarcoma and leucosis virus envelop-receptor pairs.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Metabotropic glutamate receptor dependent slow calcium oscillations were observed in the medium spiny projection neurons of striatum.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Control of emotion and its memory by monoamines. Neural network that mediates selection and flexibility of behaviors: Roles of striatal input pathways

      More details

    Event date: 2014.10

  • Corticothalamic and corticocortical cells in mouse M1 exhibit layer- and area-specific elaboration of axon collaterals.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Expressing designer receptors exclusively activated by designer drags on the frontostriatal projection neurons in the primate brain using double viral vector transfection.

    44th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2014.10

  • Dorsal striatal indirect pathway regulates the performance of auditory conditional discrimination.

    16th International Society of Addiction Medicine Annual Meeting  

      More details

    Event date: 2014.10

  • Genetic co-regulation of the nigrostriatal dopaminergic function by V-1 gene via the Rho-MAL-SRF pathway in vitro and in vivo

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Behavioral flexibility is inhibited by cholinergic interneurons in the dorsomedial striatum, via muscarinic M4 receptors

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Striatal indirect pathway from the dorsomedial striatum regulates the performance of conditional discrimination through controlling perseverative response

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Thalamostriatal system that regulates response selection and flexibility

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Optimizing the junction of glycoprotein for the transduction efficiency of a lentiviral vector for neuron-specific retrograde gene transfer

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Physical roles of corticostriatal pathways in the basal ganglia

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Direct and indirect striatal projection neurons exhibited slow calcium oscillations

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • Three orthogonal Gate-Tag vectors for pathway-specific gene transfer in the mammalian brain

    The 37th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2014.9

  • 認知記憶における前脳基底部コリン作動性神経系の役割:新しい認知症病態モデル

    第11回臨床・基礎研究交流会  

      More details

    Event date: 2014.7

  • ウィルスベクターによる神経回路の標識と制御

    第一回脳機能医工学研究センターセミナー  

      More details

    Event date: 2014.7

  • 線条体アセチルコリン神経伝達による行動柔軟性の制御

    新潟大学脳研究所特別講演会  

      More details

    Event date: 2014.4

  • ウイルスベクターによる神経回路の標識と制御

    多次元脳トレーニング&レクチャー「ヒト、サル、ラットの脳解剖から学習・認知の理解へ」  

      More details

    Event date: 2014.3

  • 行動の選択と柔軟性を制御する神経ネットワーク:遺伝子操作による特定神経回路の改変と制御

    浜松医科大学セミナー  

      More details

    Event date: 2014.2

  • Key roles of striatal indirect pathway in response selection accuracy of auditory discrimination.

    43rd Annual Meeting of Society for Neuroscienc  

      More details

    Event date: 2013.11

  • Verified contribution of propriospinal neurons to recovery of hand dexterity after a corticospinal tract lesion in the monkey.

    43rd Annual Meeting of Society for Neuroscienc  

      More details

    Event date: 2013.11

  • Effects of specific immunotoxin lesion of noradrenergic neurons in the locus coeruleus on the state of wakefulness in mice.

    43rd Annual Meeting of Society for Neuroscienc  

      More details

    Event date: 2013.11

  • V-1 maintains and augments nigrostriatal dopaminergic function through actin polymerization in vitro and in vivo.

    43rd Annual Meeting of Society for Neuroscienc  

      More details

    Event date: 2013.11

  • Functional control of specific neural pathways in basal ganglia circuit by HiRet vector-mediated transgene expression.

    43rd Annual Meeting of Society for Neuroscienc  

      More details

    Event date: 2013.11

  • 線条体間接路を介する刺激弁別学習の実行制御

    第45回東北生理談話会  

      More details

    Event date: 2013.10

  • 線条体淡蒼球路を介する聴覚性弁別学習の制御

    第28回日本大脳基底核研究会  

      More details

    Event date: 2013.7

  • High level expression of channelrhodopsin gene in specific neural pathways induced by double transduction system with HiRet vector

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Physiological roles of striatal projection neurons in voluntary movements

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Differential labeling of the cortical projection neuron subpopulations by TET-double infection method (TEDI)

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Behavioral flexibility inhibited by cholinergic interneurons in the dorsomedial striatum

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Highly efficient retrograde gene delivery into motor neurons by lentiviral vector pseudotyped with fusion glycoprotein

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • 神経回路機能の遺伝子操作と制御に向けたウイルスベクター技術

    Neuro2013 第36回日本神経科学大会、第56回日本神経化学会大会、第23回日本神経回路学会大会  

      More details

    Event date: 2013.6

  • Comparative analysis for behavioral roles of the central lateral and parafaacicular nuclear froups projecting to the dorsolateral striatum

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Verified contribution of propriospinal neurons to recovery of hand dexterity after a corticospinal tract lesion in the monkey

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Selective blockade of crossed tecto-reticular pathway by double infection of viral vectors impaired orienting response in mice;methodological considerations

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Functional Analysis oof Rho GTPase Signaling in Specific Neural Pathway

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Comparison of gene transfer property through retrograde transport between the HiRet and NeuRet vectors

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Cell type-specific suppression of glutamatergic neurotransmission based on NR1-knockdown by lentiviral vector-mediated gene transfer into the transgenic rat striatum

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Behavioral roles of the striatal output pathway from the dorsomedial striatum in the auditory discrimination task

    The 36th Annual Meeting of the Japan Neurosociety, The 56th Annual Meeting of the Japanese Society for Neurochemistry, The 23rd Annual Conference of the Japanese Neural Network Society  

      More details

    Event date: 2013.6

  • Distinct behavioral roles of thalamostriatal pathways arising from the central lateral and parafascicular nuclear groups in basal ganglia function.

      More details

    Event date: 2013.6

  • Behavioral roles of the striatal indirect pathway from the dorsomedial striatum in sensory discrimination task.

      More details

    Event date: 2013.6

  • Behavioral roles of thalamostriatal pathway in sensory discrimination learning.

    Dopamine 2013  

      More details

    Event date: 2013.5

  • Striatal indirect pathway controls selection accuracy of motor response in the performance of conditional discrimination.

    11th International Basal Ganglia Society Meeting (IBAGS)  

      More details

    Event date: 2013.3

  • Phosphorylation of respiratory complex I and II by c-Src is required for neuronal viability.

      More details

    Event date: 2013.3

  • Genetic manipulation of specific neural circuits reveals behavioral and physiological roles of thalamostriatal pathways in sensory discrimination learning

      More details

    Event date: 2012.12

  • Recovery from memory deficiency of the murine model for Alzheimer's disease by rivastigmine

      More details

    Event date: 2012.11

  • Neural pathway-specific targeting reveals essential roles of thalamostriatal pathway in the acquisition and performance of sensory discrimination learning.

    42nd Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2012.10

  • Sensory input-dependent spatiotemporal regulation of neuronal turnover in the adult olfactory bulb.

    42nd Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2012.10

  • Striatopallidal neurons attenuate motor activity through the phasic response pattern in the basal ganglia.

    42nd Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2012.10

  • A microarray-based screen for transcription factors expressed in fetal pontine noradrenergic neurons and examination of their functional roles in catecholamine-synthesizing enzyme gene expression.

    42nd Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2012.10

  • Genetic dissection of the spinal circuit for hand dexterity in macaque monkeys.

    42nd Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2012.10

  • Visualization of the cortical projection neuron subtypes by TET-double infection method (TEDI).

    42nd Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2012.10

  • 学習の獲得と実行を媒介する神経ネットワーク:遺伝子操作による特定神経回路の改変と制御

    奈良医大セミナー  

      More details

    Event date: 2012.10

  • Striatopallidal pathway from the dorsal striatum contributes to selection accuracy of auditory discrimination

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Selective activation of the cortico-striatal pathway by optogenetics with retrograde gene transfer

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Selective gene expression in nigral dopamine neurons by the use of modified lentiviral vectors with enhanced retrograde transfer in primates

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Influence of specific immunotoxic lesion of the noradrenergic neurons in the locus coeruleus on sleep-wake cycle in mice

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Selective elimination of the cortico-subthalamic "hyperdirect" pathway by the use of immunotoxin-mediated tract targeting in primates

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Selective neural pathway targeting reveals key roles of thalamostriatal projection in the control of conditional response assosiation

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Ryoji Fukabori, Kana Okada, Kayo Nishizawa, Nobuyuki Kai, Kenta Kobayashi, Motokazu Uchigashima, Masahiko Watanabe, Yuji Tsutsui, Kazuto Kobayashi

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Historolical analysis of transcription factors selectively expressed in noradrenergic neurons in the locus ceruleus of mice at the developmental stage

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Screening transcription factors potentiallyactivating the gene expression of noradrenaline-synthesizing enzymes in the brain

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • V1 upregulates tyrosine hydroxylase gene expression through MAL/SRF-mediated transcription coupled with actin polymerization

    The 35th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2012.9

  • Neural circuit mechanism for learning dependent on dopamine transmission.

    10th International Catecholamine Symposium (XICS)  

      More details

    Event date: 2012.9

  • V-1 stimulates Th gene transcription via actin assembley- and Notch signaling-dependent mechanisms, but represses PNMT gene expression, in catecholaminergic cells.

    10th International Catecholamine Symposium (XICS)  

      More details

    Event date: 2012.9

  • Selective ablation of dopamine beta-hydroxylase neurons (subpopulation of TH neurons) in the brain: new insights into brain catecholaminergic circuitry and catecholamine-related diseases.

    10th International Catecholamine Symposium (XICS)  

      More details

    Event date: 2012.9

  • 脳を知る最新ツール:遺伝子の運び屋ウイルスベクターって何?

    第5回脳科学研究戦略推進プログラム サイエンスカフェ  

      More details

    Event date: 2012.8

  • トランスジェニックラットに関するチュートリアル「ラット遺伝子改変技術を脳科学研究に活かすために」ラットの特徴を生かした行動解析

    包括型脳科学研究推進支援ネットワーク夏のワークショップ  

      More details

    Event date: 2012.7

  • 逆行性レンチウイルスベクターによる特定神経路の機能制御と行動生理学的解析

    包括型脳科学研究推進支援ネットワーク夏のワークショップ  

      More details

    Event date: 2012.7

  • Selective gene expression in nigral dopamine neurons by the use of modified lentiviral vectors with enhanced retrograde transfer in primates.

      More details

    Event date: 2012.7

  • 新しい遺伝子導入法により解明した、マカクザル前肢到達把持運動に関わる神経回路の機能

    包括型脳科学研究推進支援ネットワーク夏のワークショップ  

      More details

    Event date: 2012.7

  • 光遺伝学を応用した大脳皮質−線条体経路の神経生理学的機能の解明

    包括型脳科学研究推進支援ネットワーク夏のワークショップ  

      More details

    Event date: 2012.7

  • 学習行動に関わる視床線条体路の機能解析

    第27回日本大脳基底核研究会  

      More details

    Event date: 2012.7

  • 学習の獲得と実行を調節する神経ネットワーク:遺伝子操作による特定神経回路の改変と制御

    広島大学医学部神経生理セミナー  

      More details

    Event date: 2012.6

  • 学習と行動を制御する基底核神経回路のメカニズム

    青森ドーパミン研究会特別講演  

      More details

    Event date: 2012.6

  • 学習と行動の基盤となる脳内神経回路のメカニズム

    獨協医科大学基礎セミナー  

      More details

    Event date: 2012.5

  • 学習の獲得と実行を媒介する神経ネットワーク:遺伝子操作による特定神経回路の改変と制御

    国立精神神経センター・システム神経科学セミナーシリーズ  

      More details

    Event date: 2012.5

  • 学習の獲得と実行を制御する神経ネットワーク:遺伝子操作による特定神経回路の改変と制御

    名古屋大学医学部大学院セミナー  

      More details

    Event date: 2012.5

  • Control of instrumental learning through striatal projection pathways

      More details

    Event date: 2012.3

  • 脳内遺伝子導入技術を利用した行動と脳機能の研究

    霊長類研究所共同利用研究会  

      More details

    Event date: 2012.3

  • 学習と行動を制御する脳内神経回路のメカニズム

    玉川大学脳科学研究所セミナー  

      More details

    Event date: 2012.1

  • 新規融合糖タンパク質組換え体レンチウイルスベクター系による神経細胞特異的逆行性遺伝子導入

    第34回日本分子生物学会年会  

      More details

    Event date: 2011.12

  • 学習と行動を媒介する神経回路機構

    トランスジェニックラットを応用した脳科学研究の最先端」ワークショップ  

      More details

    Event date: 2011.12

  • イムノトキシン細胞標的法を用いたアルツハイマー病モデルマウスの作成とモデルマウスにおけるリバスチグミンの記憶改善

    第30回日本認知症学会学術集会  

      More details

    Event date: 2011.11

  • 遺伝子改変技術を利用した脳の回路と行動の研究

    産業医科大学大学院特別講義  

      More details

    Event date: 2011.11

  • 道具的条件付けを調節する脳内神経回路のメカニズム

    生理学研究所情動研究会  

      More details

    Event date: 2011.10

  • 学習と行動を制御する神経ネットワーク:精神・神経疾患の病態メカニズム解明へ向けて

    北海道大学精神医学講座セミナー  

      More details

    Event date: 2011.9

  • Molecular analysis of the development of the spinal nerve in the chick embryo

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Disturbance of reaching-grasping induced by the pathway-specific blockade of the signal transmission through the mid-cervical propriospinal neurons in macaque monkeys

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Application of highly efficient retrograde gene transfer vector for primate brain reserch

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Neuron-specific gene transfer system through retrograde transport of lentiviral vector for the study of structure and function of brain neural circuit

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Visualization of the corticothalamic neurons by Tet-double infection method (TEDI)

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Striatal direct pathway modulates response time in rxrcution of conditional discrimination

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Behavioral role of thalamostriatal neural pathway in conditioned discrimination paradigm

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • The development of operant matching is regulated bu the Nucleus Accumbens core

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Selective ablation of histamine H1 receptor-expressing neurons in the paraventricular nucleus of the hypothalamus to study their role in the regulation if food intake

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Modulation of emotion and memory by basal forebrain cholinergic neurons

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Remote effect of the transcranial direct current stimulation on the extracellular dopamine levels in the striatum

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Selective removal of the "hyperdirect" cortico-subthalamic pathway of the primate basal ganglia by immunotoxin-mediated neuronal ablation in combination with the use of a modified lentiviral vector with enhanced retrograde transfer

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Identification of novel transcription factors for catecholamine gene expression based upon the comprehensive analysis of transcripts in fetal pontine noradrenaergic neurons using transgenic mice expressing green fluorescent protein under the promoter of tyrosine hydroxylase

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Striatopallidal neurons regulate motor activity through the response pattern in the external segment of globus pallidus and substantia nigra pars reticulata

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Selective ablation of locus coeruleus noradrenergic neurons expressing human interleukin-2 receptor alpha-subunit in transgenic mice by a recombinant immunotoxin: exploring noradrenergic influence upon anxiety-like and depression-like bahavior

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • In vivo imaging of catecholaminergic axons in the mouse neocortex

    The 34th Annual Meeting of the Japan Neurosociety  

      More details

    Event date: 2011.9

  • Behavioral and physiological roles of straital projection pathways in instrumental learning

    23rd Biennial meeting of International Society for Neurocehmistry  

      More details

    Event date: 2011.8

  • 分子・細胞標的による脳疾患モデル研究

    第6回日本統合失調症学会  

      More details

    Event date: 2011.7

  • 震災と原発事故を教訓にして

    平成23年度生理学研究所安全衛生講習会  

      More details

    Event date: 2011.7

  • 学習と行動を制御する神経ネットワーク

    東京工業大学大学院セミナー  

      More details

    Event date: 2011.6

  • Neural circuit mechanism underlying learning and behavioral control related to dopamine transmission: Genetic analysis and manipulation of brain functions.

      More details

    Event date: 2011.6

  • Neural mechanism of basal ganglia circuit that controls acquisition and execution of learning: genetic analysis and manipulation of brain functions

      More details

    Event date: 2011.5

  • Selective ablation of histamine H1 receptor-expressing neurons in the hypothalamic paraventricular nucleus increased food intake and body weight gain

      More details

    Event date: 2011.3

  • 学習の獲得と実行を制御する脳のメカニズム:遺伝子改変技術を用いた脳神経回路の研究

    東京農業大学大学院講義  

      More details

    Event date: 2011.2

  • 遺伝子改変技術を用いた脳神経回路の研究:道具的学習の脳内機構をモデルに

    東京医科歯科大学医学研究科大学院講義  

      More details

    Event date: 2011.2

  • 脳神経回路研究のための融合糖タンパク質組換え体レンチウイルスベクター系による高頻度逆行性遺伝子導入

    第33回日本分子生物学会年会、第83回日本生化学会大会合同大会(BMB2010)  

      More details

    Event date: 2010.12

  • 高頻度逆行性輸送ウィルスベクターを用いた神経回路操作技術

    第20回日本臨床精神神経薬理学会・第40回日本神経精神薬理学会  

      More details

    Event date: 2010.9

  • The spatio-temporal context for turnover of an adult-born interneuron subtype revealed by in vivo two-photon laser ablation.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Development of pathway-selective cell manipulation methods by using lentiviral vectors with retrograde transport.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Olfactory bulb preferentially incorporates eliminated subset of newborn granule cells.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • The role of dopamine D2 receptor-expressing neurons in the nucleus accumbens core in operant matching.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Amelioration of reversal learning caused by the loss of cholinergic interneuron in the dorsomedial striatum.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Conditional Suppression of Rho GTPase Signaling Pathway in Specific Neuronal Types with Cre-loxP Recombination Driven by Double Lentiviral Vector System.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • TET-OFF lentiviral vectors drive high-level transgene expression in marmoset brains.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Behavioral analysis of the thalamostriatal neural pathway labeled by the retrograde gene transfer.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Role of the striatonigral neurons in basal ganglia in the performance of conditional discrimination task.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • Role of the striatopallidal neurons in basal ganglia in the performance of conditional discrimination task.

    Joint conference of the 33rd Annual Meeting of the Japan Neuroscience Society, the 53rd Annual Meeting of the Japanese Society for Neurochemistry and the 20th Annual Meeting of Japanese Neural Network  

      More details

    Event date: 2010.9

  • "TET-OFF" LENTIVIRAL VECTORS DRIVE HIGH-LEVEL TRANSGENE EXPRESSION IN MARMOSET BRAINS

      More details

    Event date: 2010.7

  • Highly efficient gene delivery system into the brain through retrograde axonal transport by using lentiviral vectors pseudotyped with rabies virus glycoprotein and its derivertives.

      More details

    Event date: 2010.7

  • 倉持真人、加藤成樹、高住賢司、小林憲太、小林和人

    第10回日本分子生物学学会春季シンポジウム  

      More details

    Event date: 2010.6

  • 脳神経機能研究ための高頻度逆行性輸送ベクターの開発

    第76回日本生化学会東北支部例会・シンポジウム  

      More details

    Event date: 2010.5

  • Development of the efficient gene transfer system through a lentiviral vector with retrograde axonal transport for specific neural circuit labeling.

      More details

    Event date: 2009.12

  • 学習と行動を制御する神経回路メカニズム

    北海道大学脳科学研究教育センター・シンポジウム  

      More details

    Event date: 2009.12

  • 学習と行動を司る脳のネットワーク

    CREST公開シンポジウム  

      More details

    Event date: 2009.11

  • Motor functions of dopamine D2 receptor-expressing neurons in the striatum

    The 32nd Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2009.9

  • Immunotoxin targeting of the thalamostriatal neural pathway labeled by the retrograde gene transfer

    The 32nd Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2009.9

  • Behavioral roorels of the striatonigral neural pathway in reinforcement learning

    The 32nd Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2009.9

  • Compensatory incorporation of adult-born-granule cell subtypes in the mouse olfactory bulb

    The 32nd Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2009.9

  • Essential role of Rho signaling in cranial motor axon patterning

    The 32nd Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2009.9

  • Implication of hippocampal dopamine in the conditioning of the rewarding effect of cocaine

    The 32nd Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2009.9

  • Neural circuit mechanisms underlying dopamine-dependent behaviors. Multidisciplinary approaches to basal ganglia functions.

    XXXVI International Congress of Physiological Sciences (IUPS)  

      More details

    Event date: 2009.7

  • 行動制御を媒介する脳神経回路の作動機構

    放射線医学総合研究所セミナー  

      More details

    Event date: 2009.4

  • Development of a novel lentiviral vector system for specific neural circuit labeling through retrograde axonal transport

      More details

    Event date: 2008.12

  • 遺伝子の働きを使って行動制御の仕組みをひもとく

    CREST公開シンポジウム  

      More details

    Event date: 2008.11

  • Molecular biological approaches for functional dissection of the brain neural circuitry.

    Rutgers University seminar  

      More details

    Event date: 2008.11

  • Efficient retrograde gene transfer sinto primate brain with an HIV-1 based lentiviral vector pseudotyped with rabies virus glycoprotein.

    38th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2008.11

  • Efficient gene transfer system through retrograde axonal transport with a human immunodeficiency virus type 1-based vector pseudotyped with rabies virus glycoprotein.

    38th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2008.11

  • Conditional ablation of dopamine D2 receptor-containing neurons in the nucleus accumbens shell impairs reward-related behavior.

    38th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2008.11

  • Behavioral and physiological analysis of the striatopallidal neural pathway by conditional transmission silencing.

    38th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2008.11

  • 空間学習における海馬と視床前核群の機能的連携

    第41回東北生理談話会  

      More details

    Event date: 2008.10

  • 細胞標的法による脳神経回路機能の制御

    産業技術総合研究所セミナー  

      More details

    Event date: 2008.7

  • Preferential Incorporation of mGluR2-Expressing Subtype of Granule Cells after Immunotoxin-Mediated Cell Ablation in Mouse Olfactory Bulb

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Key role of Rho/Rho-kinase signaling in cranial motor axon patterning

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Roles of two types of dopamine receptor-containing neurons of nucleus accumbens shell in reward-related behavior

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Functional analysis of the striatopallidal neural pathway by conditional transmission silencing

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Behavioral and physiological roles of the striatonigral neural pathway in motor control

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Development of a Pseudotyped HIV-1-based Lentiviral Vector Capable of Retrograde Axonal Transport

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Development of a Pseudotyped HIV-1-based Lentiviral Vector Capable of Retrograde Axonal Transport

    The 31st Annual Meeting the Japan Neuroscience Society  

      More details

    Event date: 2008.7

  • Cell targeting for functional dissection of brain neural network: Use of a retrograde transport lentiviral vector

      More details

    Event date: 2008.2

  • Essential role of the striatonigral neural pathway in motor behavior revealed by conditional ablation of dopamine D1 receptor-containing neurons in the dorsal striatum.

    BMB2007  

      More details

    Event date: 2007.12

  • Conditional ablation of dopamine D2 receptor-containing neurons in the nucleus accumbens shell impairs reward-related behavior

    BMB2007  

      More details

    Event date: 2007.12

  • アカデミアにおける環境整備

    第30回日本分子生物学会年会・第80回日本生化学会大会 合同大会  

      More details

    Event date: 2007.12

  • ドーパミン依存性行動を媒介する皮質・基底核回路のメカニズム

    第17回神経科学の基礎と臨床「大脳・基底核の基礎と臨床Up Date」  

      More details

    Event date: 2007.12

  • A lesion of the nucleus accumbens dopamine system shortens the lever-pressing inter-response time and delays response initiation in mice.

    37th Annual Meeting of Society for Neuroscience  

      More details

    Event date: 2007.11

  • Selective ablation of tenascin C-positive radial glia by diphtheria toxin-gene transfer by means of in utero electroporation.

      More details

    Event date: 2007.11

  • Key role of Rho/Rho-kinase signaling in hindbrain motor axon patterning

    Neuro2007  

      More details

    Event date: 2007.9

  • Identification and characterization of transcripts selectively expressed in the mouse locus coeruleus (Lc)

    Neuro2007  

      More details

    Event date: 2007.9

  • Increased Incorporation of Ablated Subtype of Newborn Granule Cells in the Mouse Olfactory Bulb

    Neuro2007  

      More details

    Event date: 2007.9

  • The medial prefrontal cortex controls dopamine-induced motor behavior via the subthalamic nucleus activation

    Neuro2007  

      More details

    Event date: 2007.9

  • Modulation of m opioid receptors on cholinergic interneurons in the striosome/matrix compartments of the striatum.

    Neuro2007  

      More details

    Event date: 2007.9

  • 霊長類脳研究へ向けた遺伝子改変技術

    霊長類研究所  

      More details

    Event date: 2007.9

  • ドーパミン伝達による脳機能制御の神経回路機構

    宮崎Neuroscience 研究会  

      More details

    Event date: 2007.9

  • Essential role of the striatonigral neural pathway in motor behavior revealed by conditional ablation of dopamine D1 receptor-containing neurons in the dorsal striatum.

    2nd symposium for Molecular and Cellular Cognition Society-Asia  

      More details

    Event date: 2007.9

  • 基底核研究へ向けた遺伝子改変技術

    第22回日本基底核研究会  

      More details

    Event date: 2007.8

  • Molecular Biological Approaches for Functional Dissection of the Neural Circuit Mechanism

    Tamagawa-Riken mini-Workshop on Integrative Brain Research  

      More details

    Event date: 2007.8

  • Conditional ablation of striatal neuronal types containing dopamine D1 receptors by using immunotoxin cell targeting.

    Dopamine 50 Years  

      More details

    Event date: 2007.5

  • ドーパミン神経伝達による脳機能統合の神経回路メカニズム

    2007年度農芸化学会東京大会  

      More details

    Event date: 2007.3

  • 行動神経科学への分子生物学的アプローチ

    生理学研究所大学院講義  

      More details

    Event date: 2007.3

  • Application of immunotoxin cell targeting for primate brain research

    OIST workshop on cognitive neurobiology  

      More details

    Event date: 2007.3

  • 逆行性輸送活性を有する組換え体レンチウイルスベクターの開発

    第4回CREST領域内研究報告会  

      More details

    Event date: 2007.3

  • 前頭前皮質-視床下核の機能連関によるドーパミン誘導運動の制御機構の解析

    第4回CREST領域内研究報告会  

      More details

    Event date: 2007.3

  • ドーパミンによる行動の発達と発現の制御

    第4回CREST領域内研究報告会  

      More details

    Event date: 2007.3

  • 行動の発達を調節する脳内物質:ドーパミン伝達と脳の発達障害

    CREST第2回公開シンポジウム  

      More details

    Event date: 2006.12

  • 組み換えゲノムクローン技術を利用した「セミ・ノックインマウス」の開発

    日本分子生物学会2006フォーラム  

      More details

    Event date: 2006.12

  • 脳内カテコールアミンによる脳機能発達と行動制御機構の解明

    愛媛大学医学部生化学セミナー  

      More details

    Event date: 2006.11

  • Functional dissection of the neural circuitry that mediates dopamine-related behaviors.

    Montreal University seminar  

      More details

    Event date: 2006.10

  • ドーパミン伝達による脳機能統合の神経回路メカニズム

    群馬大学医学部大学院講義  

      More details

    Event date: 2006.9

  • Key role of Rho/Rho-kinase signaling in hindbrain motor neuron development

    49th Annual Meeting of the Japanese Society for Neurochemistry  

      More details

    Event date: 2006.9

  • Noradrenergic modulation of retrieval of reconsolidated memory

    29th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Selective ablation of tenascin C-positive radial glia by diphtheria toxin-gene transfer by means of in utero electroporation

    29th Annual Meeying of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Tyrosine hydroxylase promoter-reporter- expressing cells in adult mouse olfactory bulb express calcium-binding proteins.

    29th Annual Meeying of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Selective collection of catecholaminergic (CA) neurons in the brain and its application to gene expression analysis

    29th Annual Meeying of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Obsevation for developing cerebellar cortex by acoustic impedance microscoppe

    29th Annual Meeying of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Functional links between the brainstem and hypothalamus-Roles of the noradrenergic system in emotional and stress responses

    29th Annual Meeting of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Lesion of the nucleus accumbens dopamine system shortens the lever pressing interresponse time and delays the response initiation in mice.

    29th Annual Meeying of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Prefrontal cortical dopaminergic transmission controls behavioral activation via the subthalamic nucleus activity

    29th Annual Meeying of the Japan Neuroscience Society  

      More details

    Event date: 2006.7

  • Laminin peptide YISGR modulates sensory axonal responses for dorsal spinal cord-derived chemoattractive guidance cues in higher vertebrate embryos

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  

      More details

    Event date: 2006.7

  • Essential role of Rho/Rho-kinase signaling pathway in development of hindbrain motor neurons

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  

      More details

    Event date: 2006.7

  • Immunotoxin targeting of the subthalamic neurons reveals coordination od dopamine-dependent motor behavior through differential neural pathways

    20th IUBMB International Congress of Biochemistry and Molecular Biology and 11th FAOBMB Congress  

      More details

    Event date: 2006.7

  • イムノトキシン細胞標的法と霊長類の脳機能研究への応用

    OISTワークショップ:これからの霊長類脳研究  

      More details

    Event date: 2006.5

  • The notification system for the Importation of animals

    The 83rd Annual Meeting of the Physiological Society of Japan  

      More details

    Event date: 2006.3

  • Promoting action of endogenous and exogenous epidermal growth factor-ErbB1 signals on the development of midbrain dopaminergic neurons

    83rd Annual Meeting of the Physiological Society of Japan  

      More details

    Event date: 2006.3

  • Selective collection of catecholaminergic neurons in the brain and its application to functional analyses using tyrosine hydroxylase (TH)-green fluorescent protein (GFP) transgenic mice.

    83rd Annual Meeting of the Physiological Society of Japan  

      More details

    Event date: 2006.3

  • Roles of the prefrontal cortex dopamine transmission in behavioral activation via the subthalamic nucleus

    83rd Annual Meeting of the Physiological Society of Japan  

      More details

    Event date: 2006.3

▼display all

Awards

  • 平成26年度福島医学会賞

    2015.1  

     More details

    Country:Japan

  • 平成25年度文部科学大臣表彰科学技術賞(研究部門)

    2013.5  

     More details

    Country:Japan

Research Projects

  • ジストニアの病態生理機構の解明と治療法の開発

    2007.10 - 2011.3

    小林和人、高田昌彦、南部 篤

  • 線条体投射経路を介する行動制御の神経回路メカニズム

    2007.4 - 2010.3

  • 細胞タイプ特異的な神経活動抑制のための新技術開発

    2006.4 - 2008.3

  • ドーパミン神経の生理機能におけるRho GTPase シグナル伝達系の役割」(小林 和人、Louis-Eric trudeau)平成18年度―19年度(125万円)

    2006.4 - 2008.3

    小林 和人、Louis-Eric Trudeau(共同出願)、小林憲太

  • ドーパミン伝達による行動の発達と発現の制御機構

    2005.10 - 2010.10

    小林 和人、八十島安伸、甲斐信行、小林憲太

  • 線条体GABA性インターニューロンの行動生理学的役割に関する研究

    2004.4 - 2007.3

▼display all