Updated on 2022/07/29

写真a

 
TAMURA Naoki
 
Organization
School of Medicine (Life Sciences and Social Medicine) Department of Anatomy and Histology Assistant Professor
Title
Assistant Professor

Degree

  • Ph.D.(Agriculture) ( 2013.3   Kyoto University )

Research Interests

  • オートファジー、イノシトールリン脂質、液胞/リソソーム

Research Areas

  • Life Science / Applied molecular and cellular biology  / Applied Molecular Cell Biology

  • Life Science / Cell biology  / Cell Biology

  • Life Science / Functional biochemistry  / Functional Biochemistry

  • Life Science / Anatomy

Education

  • Kyoto University   Graduate School, Division of Agriculture

    - 2012.3

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    Country: Japan

  • Kyoto University   Graduate School, Division of Agriculture

    - 2007.3

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    Country: Japan

  • Tohoku University   Faculty of Agriculture

    - 2005.3

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    Country: Japan

Research History

  • Fukushima Medical University   Assistant Professor

    2017.2 - Now

  • Fukushima Medical University

    2014.7 - Now

  • Osaka University IPR

    2012.4 - 2014.6

Papers

  • Loss of <i>Atg2b</i> and <i>Gskip</i> impairs the maintenance of the hematopoietic stem cell pool size.

    Sakai SS, Hasegawa A, Ishimura R, Tamura N, Kageyama S, Komatsu-Hirota S, Abe M, Ling Y, Okuda S, Funayama M, Kikkawa M, Miura Y, Sakimura K, Narita I, Waguri S, Shimizu R, Komatsu M

    Molecular and cellular biology   MCB0002421   2021.11( ISSN:0270-7306

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1128/MCB.00024-21

    PubMed

  • p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response.

    Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M

    Nature communications   12 ( 1 )   16   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1038/s41467-020-20185-1

    PubMed

  • オートファジーは全身性強皮症の硬化期に関与する(Autophagy is involved in the sclerotic phase of systemic sclerosis)

    Mori Tatsuhiko, Tamura Naoki, Waguri Satoshi, Yamamoto Toshiyuki

    Fukushima Journal of Medical Science   66 ( 1 )   17 - 24   2020.4( ISSN:0016-2590

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Membrane Tethering Potency of Rab-Family Small GTPases Is Defined by the C-Terminal Hypervariable Regions.

    Ueda S, Tamura N, Mima J

    Frontiers in cell and developmental biology   8   577342   2020

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3389/fcell.2020.577342

    PubMed

  • Hyperosmotic stress induces unconventional autophagy independent of the Ulk1 complex.

    Tamura N, Kageyama S, Komatsu M, Waguri S

    Molecular and cellular biology   2019.6( ISSN:0270-7306

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1128/MCB.00024-19

    PubMed

  • Homotypic and heterotypic trans-assembly of human Rab-family small GTPases in reconstituted membrane tethering

    Kazuya Segawa, Naoki Tamura, Joji Mima

    Journal of Biological Chemistry   2019.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1074/jbc.RA119.007947

    PubMed

  • LC3-positive puncta increase in skeletal muscle of patient-derived xenograft mice

    Annoh Hiromichi, Dobashi Yuu, Tamura Naoki, Uemura Takefumi, Waguri Satoshi

    Japanese Journal of Physical Fitness and Sports Medicine   67 ( 1 )   99 - 105   2018.1( ISSN:0039906X

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.7600/jspfsm.67.99

  • Atg21 regulates pexophagy via its PI (3) P‐binding activity in Pichia pastoris

    Naoki Tamura, Masahide Oku, Yasuyoshi Sakai

    FEMS yeast research   14 ( 3 )   435 - 444   2014.5

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    Language:English   Publishing type:Research paper (other academic)  

  • Membrane-anchored human Rab GTPases directly mediate membrane tethering in vitro

    Naoki Tamura, Joji Mima

    Biology open   3 ( 11 )   1108 - 1115   2014( ISSN:2046-6390

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1242/bio.20149340

    J-GLOBAL

  • Atg18 lifts up from and lands on the vacuolar membrane mediated by phosphorylation of its propellers

    Masahide Oku, Naoki Tamura, Yasuyoshi Sakai

    Autophagy   9 ( 12 )   2161 - 2162   2013.10

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Atg18 phosphoregulation controls organellar dynamics by modulating its phosphoinositide-binding activity

    Naoki Tamura, Masahide Oku, Moemi Ito, Nobuo N Noda, Fuyuhiko Inagaki, Yasuyoshi Sakai

    The Journal of cell biology   202 ( 4 )   685 - 698   2013.8

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    Language:English   Publishing type:Research paper (other academic)  

  • Atg8 regulates vacuolar membrane dynamics in a lipidation-independent manner in Pichia pastoris

    Naoki Tamura, Masahide Oku, Yasuyoshi Sakai

    Journal of cell science   123 ( 23 )   4107 - 4116   2010.12

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    Language:English   Publishing type:Research paper (other academic)  

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Books

  • 化学と生物

    (メチロトロフ酵母における多様なオートファジー経路とその生理機能)

    日本農芸化学会  2014.12 

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    Language:Japanese  

    Authors name of the chapter and paper which it took charge of:奥 公秀、田村直輝、阪井康能  

Presentations

  • 高浸透圧ストレス下で形成される非膜性オルガネラの比較解析

    第74回日本細胞生物学会大会  

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    Event date: 2022.6

  • 高浸透圧ストレスに応答した非膜性オルガネラの形成・分解機序

    第127回日本解剖学会総会・全国学術集会  

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    Event date: 2022.3

  • 高浸透圧ストレスに応答した非膜性オルガネラの形成・分解機序

    第73回日本細胞生物学会大会  

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    Event date: 2021.6 - 2021.7

  • 高浸透圧ストレス下における非膜性オルガネラの形成と分解

    日本解剖学会第66回東北・北海道連合支部学術集会  

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    Event date: 2020.9

  • 高浸透圧ストレス変動に応答したp62顆粒およびストレス顆粒の形成・消失機序

    第72回日本細胞生物学会大会  

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    Event date: 2020.6

  • 高浸透圧ストレス下におけるオートファジー分子の機能解析

    第61回 日本脂質生化学会  

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    Event date: 2019.7

  • 高浸透圧ストレス下におけるWIPI2の後期エンドソ―ム局在について

    第124回日本解剖学会総会・全国学術集会  

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    Event date: 2019.3

  • 高浸透圧ストレス下におけるWIPI2の後期エンドソ―ム局在について

    第124回日本解剖学会総会・全国学術集会  

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    Event date: 2019.3

  • 高浸透圧ストレス誘導性オートファジーの分子メカニズムの解析

    第123回日本解剖学会総会・全国学術集会  

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    Event date: 2018.3

  • 高浸透圧ストレス誘導性オートファジーの分子メカニズムの解析

    第123回日本解剖学会総会・全国学術集会  

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    Event date: 2018.3

  • 浸透圧ストレス誘導性オートファジーの分子機構の解明

    第69回日本細胞生物学会大会  

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    Event date: 2017.6

  • Phenotypic analysis of mice defective in Atg2A/B 

    第69回日本細胞生物学会大会  

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    Event date: 2017.6

  • 浸透圧ストレス誘導性オートファジーの分子機構の解明

    第69回日本細胞生物学会大会  

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    Event date: 2017.6

  • 高浸透圧ストレス誘導性オートファジーの形態および分子メカニズムの解析

    日本農芸化学会2017年度大会  

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    Event date: 2017.3

  • オートファジー関連分子WIPI-1、WIPI-2 の浸透圧ストレスへの関与

    第62回日本解剖学会 東北・北海道連合支部学術集会  

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    Event date: 2016.9

  • WIPI-1 and WIPI-2 are involved in osmotic stress in mammalian cells

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    Event date: 2016.6

  • オートファジー関連分子WIPI-1、WIPI-2 の浸透圧ストレスへの関与

    第62回日本解剖学会 東北・北海道連合支部学術集会  

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    Event date: 2016

  • WIPI-1 and WIPI-2 are involved in osmotic stress in mammalian cells

    WIPI-1 and WIPI-2 are involved in osmotic stress in mammalian cells  

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    Event date: 2016

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Research Projects

  • 非膜性オルガネラの多面的な形態学解析

    2022.4 - 2025.3

  • オートファジーにおける隔離膜伸長過程の多角的な微細構造解析

    2019.4 - 2022.3

  • PI(3,5)P2結合因子としてのWIPI familyの解析

    2015.4 - 2018.3