論文 - 高木 基樹
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海洋由来の放線菌が産生する二次代謝産物の新規薬剤探索ライブラリーの構築
高木 基樹、新家 一男
バイオサイエンスとインダストリー 72 ( 2 ) 208 - 212 2014年5月
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Actinoplanes missouriensisからの新規プレニル化インドール誘導体3-hydroxy-6-dimethylallylindolin-2-oneの単離、構造決定および生合成(Isolation, structural elucidation and biosynthesis of 3-hydroxy-6-dimethylallylindolin-2-one, a novel prenylated indole derivative from Actinoplanes missouriensis)
Satou Ryutaro, Izumikawa Miho, Katsuyama Yohei, Matsui Misato, Takagi Motoki, Shin-ya Kazuo, Ohnishi Yasuo
The Journal of Antibiotics 67 ( 3 ) 231 - 236 2014年3月（ ISSN:0021-8820 ）
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Total synthesis and characterization of thielocin B1 as a protein–protein interaction inhibitor of PAC3 homodimer.
Doi T, Yoshida M, Ohsawa K, Shin-ya K, Takagi M, Uekusa Y, Yamaguchi T, Kato K, Hirokawa T, Natsume T.
Chem Sci. 5 1860 - 1868 2014年
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Isolation, structural elucidation and biosynthesis of 3-hydroxy-6-dimethylallylindolin-2-one, a novel prenylated indole derivative from Actinoplanes missouriensis.
Satou R, Izumikawa M, Katsuyama Y, Matsui M, Takagi M, Shin-ya K, Ohnishi Y.
J Antibiot. 67 231 - 236 2014年
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Shibata K., Yoshida M., Takahashi T., Takagi M., Shin-Ya K., Doi T.
Bulletin of the Chemical Society of Japan 86 ( 12 ) 1453 - 1465 2013年12月（ ISSN:00092673 ）
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Spectomycin B1 as a novel sumoylation inhibitor that directly binds to SUMO E2
Hirohama M., Kumar A., Fukuda I., Matsuoka S., Igarashi Y., Saitoh H., Takagi M., Shin-Ya K., Honda K., Kondoh Y., Saito T., Nakao Y., Osada H., Zhang K., Yoshida M., Ito A.
ACS Chemical Biology 8 ( 12 ) 2635 - 2642 2013年12月（ ISSN:15548929 ）
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Isaria種NBRC 104353由来の新規ピリドンアルカロイドJBIR-130、JBIR-131、JBIR-132(New pyridone alkaloids JBIR-130, JBIR-131 and JBIR-132 from Isaria sp. NBRC 104353)
Hosoya Takahiro, Takagi Motoki, Shin-ya Kazuo
The Journal of Antibiotics 66 ( 4 ) 235 - 238 2013年4月（ ISSN:0021-8820 ）
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Total Synthesis of Destruxin E and its Derivatives
YOSHIDA Masahito, ISHIDA Yoshitaka, TAKEUCHI Hisayuki, NAKAGAWA Hiroshi, YASHIRODA Yoko, YOSHIDA Minoru, TAKAGI Motoki, SHIN-YA Kazuo, DOI Takayuki
Peptide science : proceedings of the ... Japanese Peptide Symposium 2012 95 - 96 2013年3月（ ISSN:13447661 ）
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Synthesis of hepta-oxazole macrocyclic analogues of telomestatin and evaluation of their telomerase inhibitory activities.
Shibata K, Yoshida M, Takahashi T, Takagi M, Shin-ya K, Doi T.
Bull. Chem. Soc. Jpn 86 1453 - 1465 2013年
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Spectomycin B1 as a Novel SUMOylation Inhibitor That Directly Binds to SUMO E2.
Hirohama M, Kumar A, Fukuda I, Matsuoka S, Igarashi Y, Saitoh H, Takagi M, Shin-ya K, Honda K, Kondoh Y, Saito T, Nakao Y, Osada H, Zhang KY, Yoshida M, Ito A.
ACS Chem Biol. 8 2635 - 2642 2013年
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JBIR-107, a new metabolite from the marine-sponge-derived actinomycete, Streptomyces tateyamensis NBRC 105047.
Izumikawa M, Kawahara T, Hwang JH, Takagi M, Shin-ya K.
Biosci Biotechnol Biochem. 77 663 - 665 2013年
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Engineered Streptomyces avermitilis Host for Heterologous Expression of Biosynthetic Gene Cluster for Secondary Metabolites.
Komatsu M, Komatsu K, Koiwai H, Yamada Y, Kozone I, Izumikawa M, Hashimoto J, Takagi M, Omura S, Shin-ya K, Cane DE, Ikeda H.
ACS Synth Biol. 2 384 - 396 2013年
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Design and synthesis of 2-phenyl-1,4-dioxa-spiro[4.5]deca-6,9-dien-8-ones as potential anticancer agents starting from cytotoxic spiromamakone A.
Fuse S, Inaba K, Takagi M, Tanaka M, Hirokawa T, Johmoto K, Uekusa H, Shin-ya K, Takahashi T, Doi T.
Eur J Med Chem. 66 180 - 184 2013年
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A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis.
Maruyama C, Toyoda J, Kato Y, Izumikawa M, Takagi M, Shin-ya K, Katano H, Utagawa T, Hamano Y.
Nat Chem Biol 8 ( 9 ) 791 - 797 2012年9月
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Construction of a natural product library containing secondary metabolites produced by actinomycetes.
Takagi M, Shin-ya K.
J Antibiot. 65 443 - 447 2012年
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Tyrosyl-DNA Phosphodiesterase 1 Inhibitor from an Anamorphic Fungus.
Takagi M, Ueda JY, Hwang JH, Hashimoto J, Izumikawa M, Murakami H, Sekido Y and Shin-ya K.
J Nat Prod 75 764 - 767 2012年
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JBIR-124: a novel antioxidative agent from a marine sponge-derived fungus Penicillium citrinum SpI080624G1f01.
Kawahara T, Takagi M and Shin-ya K
J Antibiot 65 45 - 47 2012年
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A new cyclizidine analog-JBIR-102-from Saccharopolyspora sp. RL78 isolated from mangrove soil.
Izumikawa M, Hosoya T, Takagi M and Shin-ya K
J Antibiot 65 41 - 43 2012年
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JBIR-94 and JBIR-125, Antioxidative Phenolic Compounds from Streptomyces sp. R56-07.
Kawahara T, Izumikawa M, Otoguro M, Yamamura H, Hayakawa M, Takagi M and Shin-ya K
J Nat Prod 75 107 - 110 2012年
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JBIR-78 and JBIR-95: Phenylacetylated peptides isolated from Kibdelosporangium sp. AK-AA56.
Izumikawa M, Takagi M and Shin-ya K
J Nat Prod 75 280 - 284 2012年