Updated on 2024/03/18

写真a

 
WAGURI Satoshi
 
Organization
School of Medicine (Life Sciences and Social Medicine) Department of Anatomy and Histology Chairman of the Department
Title
Chairman of the Department

Degree

  • 博士(医学) ( 1992.3   筑波大学 )

Research Interests

  • autophagy

  • liquid-liquid phase separation

  • vesicular transport

  • electron microscopy

  • lysosome

  • 細胞内凝集体

  • 成長因子受容体

  • 金コロイド免疫電顕法

  • live-cell imaging

  • メンブレントラフィック

  • trans-Golgi network

  • autophagy

  • endosome

  • cancer

Research Areas

  • Life Science / Anatomy  / "Anatomy in General (including Histology, Embryology)"

  • Life Science / Cell biology

  • Life Science / Tumor biology

Research History

  • Fukushima Medical University   Chairman of the Department

    2017.2 - Now

Professional Memberships

  • Japanese Association of Anatomists

  • 日本細胞生物学会

  • JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY

  • JAPANESE SOCIETY OF NEUROLOGY

  • THE JAPANESE CANCER ASSOCIATION

Committee Memberships

  • 日本解剖学会   評議員  

       

  • 日本解剖学会   評議員  

       

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    Committee type:Academic society

Papers

  • Endosomal protein expression of γ1-adaptin is associated with tumor growth activity and relapse-free survival in breast cancer.

    Hoshi N, Uemura T, Tachibana K, Abe S, Murakami-Nishimagi Y, Okano M, Noda M, Saito K, Kono K, Ohtake T, Waguri S

    Breast cancer (Tokyo, Japan)   31 ( 2 )   305 - 316   2024.1( ISSN:1340-6868

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    Language:English  

    DOI : 10.1007/s12282-023-01539-1

    PubMed

  • ATG9A supports <i>Chlamydia trachomatis</i> infection via autophagy-independent mechanisms

    Michitaka Suzuki, Tomoko Funakoshi, Keigo Kumagai, Masaaki Komatsu, Satoshi Waguri

    Microbiology Spectrum   11 ( 5 )   e0277423   2023.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1128/spectrum.02774-23

    PubMed

  • Phosphorylation of phase-separated p62 bodies by ULK1 activates a redox-independent stress response.

    Ryo Ikeda, Daisuke Noshiro, Hideaki Morishita, Shuhei Takada, Shun Kageyama, Yuko Fujioka, Tomoko Funakoshi, Satoko Komatsu-Hirota, Ritsuko Arai, Elena Ryzhii, Manabu Abe, Tomoaki Koga, Hozumi Motohashi, Mitsuyoshi Nakao, Kenji Sakimura, Arata Horii, Satoshi Waguri, Yoshinobu Ichimura, Nobuo N Noda, Masaaki Komatsu

    The EMBO journal   42 ( 14 )   e113349   2023.7( ISSN:0261-4189

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.15252/embj.2022113349

    PubMed

  • Tissue-Engineered Hepatocyte Sheets Supplemented with Adipose-Derived Stem Cells.

    Suzushino S, Sato N, Ishigame T, Okada R, Kofunato Y, Watanabe J, Muto M, Tsukida S, Nishimagi A, Kimura T, Kenjo A, Waguri S, Marubashi S

    Tissue engineering. Part A   29 ( 13-14 )   384 - 396   2023.7( ISSN:1937-3341

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    Language:English  

    DOI : 10.1089/ten.TEA.2022.0197

    PubMed

  • "I'd like to let people know what we did:" values of Fukushima medical students following the Great East Japan Earthquake.

    Stacy A, Lange M, Katz CL, Waguri S, Yanagisawa R

    BMC medical education   23 ( 1 )   248   2023.4

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    Language:English  

    DOI : 10.1186/s12909-022-03887-6

    PubMed

  • STING signalling is terminated through ESCRT-dependent microautophagy of vesicles originating from recycling endosomes.

    Yoshihiko Kuchitsu, Kojiro Mukai, Rei Uematsu, Yuki Takaada, Ayumi Shinojima, Ruri Shindo, Tsumugi Shoji, Shiori Hamano, Emari Ogawa, Ryota Sato, Kensuke Miyake, Akihisa Kato, Yasushi Kawaguchi, Masahiko Nishitani-Isa, Kazushi Izawa, Ryuta Nishikomori, Takahiro Yasumi, Takehiro Suzuki, Naoshi Dohmae, Takefumi Uemura, Glen N Barber, Hiroyuki Arai, Satoshi Waguri, Tomohiko Taguchi

    Nature cell biology   25 ( 3 )   453 - 466   2023.3( ISSN:1465-7392

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1038/s41556-023-01098-9

    PubMed

    PubMed Central

  • The UFM1 system regulates ER-phagy through the ufmylation of CYB5R3.

    Ryosuke Ishimura, Afnan H El-Gowily, Daisuke Noshiro, Satoko Komatsu-Hirota, Yasuko Ono, Mayumi Shindo, Tomohisa Hatta, Manabu Abe, Takefumi Uemura, Hyeon-Cheol Lee-Okada, Tarek M Mohamed, Takehiko Yokomizo, Takashi Ueno, Kenji Sakimura, Tohru Natsume, Hiroyuki Sorimachi, Toshifumi Inada, Satoshi Waguri, Nobuo N Noda, Masaaki Komatsu

    Nature communications   13 ( 1 )   7857 - 7857   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1038/s41467-022-35501-0

    PubMed

    PubMed Central

  • Lack of hepatic autophagy promotes severity of liver injury but not steatosis

    Wen-Xing Ding, Hong-Min Ni, Satoshi Waguri, Masaaki Komatsu

    Journal of Hepatology   77 ( 5 )   1458 - 1459   2022.5( ISSN:0168-8278

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.jhep.2022.05.015

    PubMed

  • Loss of Atg2b and Gskip Impairs the Maintenance of the Hematopoietic Stem Cell Pool Size

    Shun-suke Sakai, Atsushi Hasegawa, Ryosuke Ishimura, Naoki Tamura, Shun Kageyama, Satoko Komatsu-Hirota, Manabu Abe, Yiwei Ling, Shujiro Okuda, Manabu Funayama, Mika Kikkawa, Yoshiki Miura, Kenji Sakimura, Ichiei Narita, Satoshi Waguri, Ritsuko Shimizu, Masaaki Komatsu

    Molecular and Cellular Biology   42 ( 1 )   e0002421   2022.1( ISSN:0270-7306

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1128/MCB.00024-21

    PubMed

  • Clathrin adapters AP-1 and GGA2 support expression of epidermal growth factor receptor for cell growth

    Uemura T, Suzuki T, Dohmae N, Waguri S.

    Oncogenesis   10 ( 11 )   80   2021.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : doi: 10.1038/s41389-021-00367-2.

  • Arf GTPase-activating proteins SMAP1 and AGFG2 regulate the size of Weibel-Palade bodies and exocytosis of von Willebrand factor

    Watanabe A, Hataida H, Inoue N, Kamon K, Baba K, Sasaki K, Kimura R, Sasaki H, Eura Y, Ni WF, Shibasaki Y, Waguri S, Kokame K, Shiba Y.

    Biology Open   10 ( 9 )   16   2021.9

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : doi: 10.1242/bio.058789.

  • p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

    Kageyama S, Gudmundsson SR, Sou YS, Ichimura Y, Tamura N, Kazuno S, Ueno T, Miura Y, Noshiro D, Abe M, Mizushima T, Miura N, Okuda S, Motohashi H, Lee JA, Sakimura K, Ohe T, Noda NN, Waguri S, Eskelinen EL, Komatsu M.

    Nature Communications   12 ( 1 )   16   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : doi: 10.1038/s41467-020-20185-1

  • Homeostatic regulation of STING by retrograde membrane traffic to the ER

    Mukai K, Ogawa E, Uematsu R, Kuchitsu Y, Kiku F, Uemura T, Waguri S, Suzuki T, Dohmae N, Arai H, Shum AK, Taguchi T.

    Nature Communications   12 ( 1 )   61   2021.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : doi: 10.1038/s41467-020-20234-9

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(1).

    Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, Agam G, Agarwal A, Aggarwal BB, Agnello M, Agostinis P, Agrewala JN, Agrotis A, Aguilar PV, Ahmad ST, Ahmed ZM, Ahumada-Castro U, Aits S, Aizawa S, Akkoc Y, Akoumianaki T, Akpinar HA, Al-Abd AM, Al-Akra L, Al-Gharaibeh A, Alaoui-Jamali MA, Alberti S, Alcocer-Gómez E, Alessandri C, Ali M, Alim Al-Bari MA, Aliwaini S, Alizadeh J, Almacellas E, Almasan A, Alonso A, Alonso GD, Altan-Bonnet N, Altieri DC, Álvarez ÉMC, Alves S, Alves da Costa C, Alzaharna MM, Amadio M, Amantini C, Amaral C, Ambrosio S, Amer AO, Ammanathan V, An Z, Andersen SU, Andrabi SA, Andrade-Silva M, Andres AM, Angelini S, Ann D, Anozie UC, Ansari MY, Antas P, Antebi A, Antón Z, Anwar T, Apetoh L, Apostolova N, Araki T, Araki Y, Arasaki K, Araújo WL, Araya J, Arden C, Arévalo MA, Arguelles S, Arias E, Arikkath J, Arimoto H, Ariosa AR, Armstrong-James D, Arnauné-Pelloquin L, Aroca A, Arroyo DS, Arsov I, Artero R, Asaro DML, Aschner M, Ashrafizadeh M, Ashur-Fabian O, Atanasov AG, Au AK, Auberger P, Auner HW, Aurelian L, Autelli R, Avagliano L, Ávalos Y, Aveic S, Aveleira CA, Avin-Wittenberg T, Aydin Y, Ayton S, Ayyadevara S, Azzopardi M, Baba M, Backer JM, Backues SK, Bae DH, Bae ON, Bae SH, Baehrecke EH, Baek A, Baek SH, Baek SH, Bagetta G, Bagniewska-Zadworna A, Bai H, Bai J, Bai X, Bai Y, Bairagi N, Baksi S, Balbi T, Baldari CT, Balduini W, Ballabio A, Ballester M, Balazadeh S, Balzan R, Bandopadhyay R, Banerjee S, Banerjee S, Bánréti Á, Bao Y, Baptista MS, Baracca A, Barbati C, Bargiela A, Barilà D, Barlow PG, Barmada SJ, Barreiro E, Barreto GE, Bartek J, Bartel B, Bartolome A, Barve GR, Basagoudanavar SH, Bassham DC, Bast RC Jr, Basu A, Batoko H, Batten I, Baulieu EE, Baumgarner BL, Bayry J, Beale R, Beau I, Beaumatin F, Bechara LRG, Beck GR Jr, Beers MF, Begun J, Behrends C, Behrens GMN, Bei R, Bejarano E, Bel S, Behl C, Belaid A, Belgareh-Touzé N, Bellarosa C, Belleudi F, Belló Pérez M, Bello-Morales R, Beltran JSO, Beltran S, Benbrook DM, Bendorius M, Benitez BA, Benito-Cuesta I, Bensalem J, Berchtold MW, Berezowska S, Bergamaschi D, Bergami M, Bergmann A, Berliocchi L, Berlioz-Torrent C, Bernard A, Berthoux L, Besirli CG, Besteiro S, Betin VM, Beyaert R, Bezbradica JS, Bhaskar K, Bhatia-Kissova I, Bhattacharya R, Bhattacharya S, Bhattacharyya S, Bhuiyan MS, Bhutia SK, Bi L, Bi X, Biden TJ, Bijian K, Billes VA, Binart N, Bincoletto C, Birgisdottir AB, Bjorkoy G, Blanco G, Blas-Garcia A, Blasiak J, Blomgran R, Blomgren K, Blum JS, Boada-Romero E, Boban M, Boesze-Battaglia K, Boeuf P, Boland B, Bomont P, Bonaldo P, Bonam SR, Bonfili L, Bonifacino JS, Boone BA, Bootman MD, Bordi M, Borner C, Bornhauser BC, Borthakur G, Bosch J, Bose S, Botana LM, Botas J, Boulanger CM, Boulton ME, Bourdenx M, Bourgeois B, Bourke NM, Bousquet G, Boya P, Bozhkov PV, Bozi LHM, Bozkurt TO, Brackney DE, Brandts CH, Braun RJ, Braus GH, Bravo-Sagua R, Bravo-San Pedro JM, Brest P, Bringer MA, Briones-Herrera A, Broaddus VC, Brodersen P, Brodsky JL, Brody SL, Bronson PG, Bronstein JM, Brown CN, Brown RE, Brum PC, Brumell JH, Brunetti-Pierri N, Bruno D, Bryson-Richardson RJ, Bucci C, Buchrieser C, Bueno M, Buitrago-Molina LE, Buraschi S, Buch S, Buchan JR, Buckingham EM, Budak H, Budini M, Bultynck G, Burada F, Burgoyne JR, Burón MI, Bustos V, Büttner S, Butturini E, Byrd A, Cabas I, Cabrera-Benitez S, Cadwell K, Cai J, Cai L, Cai Q, Cairó M, Calbet JA, Caldwell GA, Caldwell KA, Call JA, Calvani R, Calvo AC, Calvo-Rubio Barrera M, Camara NO, Camonis JH, Camougrand N, Campanella M, Campbell EM, Campbell-Valois FX, Campello S, Campesi I, Campos JC, Camuzard O, Cancino J, Candido de Almeida D, Canesi L, Caniggia I, Canonico B, Cantí C, Cao B, Caraglia M, Caramés B, Carchman EH, Cardenal-Muñoz E, Cardenas C, Cardenas L, Cardoso SM, Carew JS, Carle GF, Carleton G, Carloni S, Carmona-Gutierrez D, Carneiro LA, Carnevali O, Carosi JM, Carra S, Carrier A, Carrier L, Carroll B, Carter AB, Carvalho AN, Casanova M, Casas C, Casas J, Cassioli C, Castillo EF, Castillo K, Castillo-Lluva S, Castoldi F, Castori M, Castro AF, Castro-Caldas M, Castro-Hernandez J, Castro-Obregon S, Catz SD, Cavadas C, Cavaliere F, Cavallini G, Cavinato M, Cayuela ML, Cebollada Rica P, Cecarini V, Cecconi F, Cechowska-Pasko M, Cenci S, Ceperuelo-Mallafré V, Cerqueira JJ, Cerutti JM, Cervia D, Cetintas VB, Cetrullo S, Chae HJ, Chagin AS, Chai CY, Chakrabarti G, Chakrabarti O, Chakraborty T, Chakraborty T, Chami M, Chamilos G, Chan DW, Chan EYW, Chan ED, Chan HYE, Chan HH, Chan H, Chan MTV, Chan YS, Chandra PK, Chang CP, Chang C, Chang HC, Chang K, Chao J, Chapman T, Charlet-Berguerand N, Chatterjee S, Chaube SK, Chaudhary A, Chauhan S, Chaum E, Checler F, Cheetham ME, Chen CS, Chen GC, Chen JF, Chen LL, Chen L, Chen L, Chen M, Chen MK, Chen N, Chen Q, Chen RH, Chen S, Chen W, Chen W, Chen XM, Chen XW, Chen X, Chen Y, Chen YG, Chen Y, Chen Y, Chen YJ, Chen YQ, Chen ZS, Chen Z, Chen ZH, Chen ZJ, Chen Z, Cheng H, Cheng J, Cheng SY, Cheng W, Cheng X, Cheng XT, Cheng Y, Cheng Z, Chen Z, Cheong H, Cheong JK, Chernyak BV, Cherry S, Cheung CFR, Cheung CHA, Cheung KH, Chevet E, Chi RJ, Chiang AKS, Chiaradonna F, Chiarelli R, Chiariello M, Chica N, Chiocca S, Chiong M, Chiou SH, Chiramel AI, Chiurchiù V, Cho DH, Choe SK, Choi AMK, Choi ME, Choudhury KR, Chow NS, Chu CT, Chua JP, Chua JJE, Chung H, Chung KP, Chung S, Chung SH, Chung YL, Cianfanelli V, Ciechomska IA, Cifuentes M, Cinque L, Cirak S, Cirone M, Clague MJ, Clarke R, Clementi E, Coccia EM, Codogno P, Cohen E, Cohen MM, Colasanti T, Colasuonno F, Colbert RA, Colell A, Čolić M, Coll NS, Collins MO, Colombo MI, Colón-Ramos DA, Combaret L, Comincini S, Cominetti MR, Consiglio A, Conte A, Conti F, Contu VR, Cookson MR, Coombs KM, Coppens I, Corasaniti MT, Corkery DP, Cordes N, Cortese K, Costa MDC, Costantino S, Costelli P, Coto-Montes A, Crack PJ, Crespo JL, Criollo A, Crippa V, Cristofani R, Csizmadia T, Cuadrado A, Cui B, Cui J, Cui Y, Cui Y, Culetto E, Cumino AC, Cybulsky AV, Czaja MJ, Czuczwar SJ, D'Adamo S, D'Amelio M, D'Arcangelo D, D'Lugos AC, D'Orazi G, da Silva JA, Dafsari HS, Dagda RK, Dagdas Y, Daglia M, Dai X, Dai Y, Dai Y, Dal Col J, Dalhaimer P, Dalla Valle L, Dallenga T, Dalmasso G, Damme M, Dando I, Dantuma NP, Darling AL, Das H, Dasarathy S, Dasari SK, Dash S, Daumke O, Dauphinee AN, Davies JS, Dávila VA, Davis RJ, Davis T, Dayalan Naidu S, De Amicis F, De Bosscher K, De Felice F, De Franceschi L, De Leonibus C, de Mattos Barbosa MG, De Meyer GRY, De Milito A, De Nunzio C, De Palma C, De Santi M, De Virgilio C, De Zio D, Debnath J, DeBosch BJ, Decuypere JP, Deehan MA, Deflorian G, DeGregori J, Dehay B, Del Rio G, Delaney JR, Delbridge LMD, Delorme-Axford E, Delpino MV, Demarchi F, Dembitz V, Demers ND, Deng H, Deng Z, Dengjel J, Dent P, Denton D, DePamphilis ML, Der CJ, Deretic V, Descoteaux A, Devis L, Devkota S, Devuyst O, Dewson G, Dharmasivam M, Dhiman R, di Bernardo D, Di Cristina M, Di Domenico F, Di Fazio P, Di Fonzo A, Di Guardo G, Di Guglielmo GM, Di Leo L, Di Malta C, Di Nardo A, Di Rienzo M, Di Sano F, Diallinas G, Diao J, Diaz-Araya G, Díaz-Laviada I, Dickinson JM, Diederich M, Dieudé M, Dikic I, Ding S, Ding WX, Dini L, Dinić J, Dinic M, Dinkova-Kostova AT, Dionne MS, Distler JHW, Diwan A, Dixon IMC, Djavaheri-Mergny M, Dobrinski I, Dobrovinskaya O, Dobrowolski R, Dobson RCJ, Đokić J, Dokmeci Emre S, Donadelli M, Dong B, Dong X, Dong Z, Dorn Ii GW, Dotsch V, Dou H, Dou J, Dowaidar M, Dridi S, Drucker L, Du A, Du C, Du G, Du HN, Du LL, du Toit A, Duan SB, Duan X, Duarte SP, Dubrovska A, Dunlop EA, Dupont N, Durán RV, Dwarakanath BS, Dyshlovoy SA, Ebrahimi-Fakhari D, Eckhart L, Edelstein CL, Efferth T, Eftekharpour E, Eichinger L, Eid N, Eisenberg T, Eissa NT, Eissa S, Ejarque M, El Andaloussi A, El-Hage N, El-Naggar S, Eleuteri AM, El-Shafey ES, Elgendy M, Eliopoulos AG, Elizalde MM, Elks PM, Elsasser HP, Elsherbiny ES, Emerling BM, Emre NCT, Eng CH, Engedal N, Engelbrecht AM, Engelsen AST, Enserink JM, Escalante R, Esclatine A, Escobar-Henriques M, Eskelinen EL, Espert L, Eusebio MO, Fabrias G, Fabrizi C, Facchiano A, Facchiano F, Fadeel B, Fader C, Faesen AC, Fairlie WD, Falcó A, Falkenburger BH, Fan D, Fan J, Fan Y, Fang EF, Fang Y, Fang Y, Fanto M, Farfel-Becker T, Faure M, Fazeli G, Fedele AO, Feldman AM, Feng D, Feng J, Feng L, Feng Y, Feng Y, Feng W, Fenz Araujo T, Ferguson TA, Fernández ÁF, Fernandez-Checa JC, Fernández-Veledo S, Fernie AR, Ferrante AW Jr, Ferraresi A, Ferrari MF, Ferreira JCB, Ferro-Novick S, Figueras A, Filadi R, Filigheddu N, Filippi-Chiela E, Filomeni G, Fimia GM, Fineschi V, Finetti F, Finkbeiner S, Fisher EA, Fisher PB, Flamigni F, Fliesler SJ, Flo TH, Florance I, Florey O, Florio T, Fodor E, Follo C, Fon EA, Forlino A, Fornai F, Fortini P, Fracassi A, Fraldi A, Franco B, Franco R, Franconi F, Frankel LB, Friedman SL, Fröhlich LF, Frühbeck G, Fuentes JM, Fujiki Y, Fujita N, Fujiwara Y, Fukuda M, Fulda S, Furic L, Furuya N, Fusco C, Gack MU, Gaffke L, Galadari S, Galasso A, Galindo MF, Gallolu Kankanamalage S, Galluzzi L, Galy V, Gammoh N, Gan B, Ganley IG, Gao F, Gao H, Gao M, Gao P, Gao SJ, Gao W, Gao X, Garcera A, Garcia MN, Garcia VE, García-Del Portillo F, Garcia-Escudero V, Garcia-Garcia A, Garcia-Macia M, García-Moreno D, Garcia-Ruiz C, García-Sanz P, Garg AD, Gargini R, Garofalo T, Garry RF, Gassen NC, Gatica D, Ge L, Ge W, Geiss-Friedlander R, Gelfi C, Genschik P, Gentle IE, Gerbino V, Gerhardt C, Germain K, Germain M, Gewirtz DA, Ghasemipour Afshar E, Ghavami S, Ghigo A, Ghosh M, Giamas G, Giampietri C, Giatromanolaki A, Gibson GE, Gibson SB, Ginet V, Giniger E, Giorgi C, Girao H, Girardin SE, Giridharan M, Giuliano S, Giulivi C, Giuriato S, Giustiniani J, Gluschko A, Goder V, Goginashvili A, Golab J, Goldstone DC, Golebiewska A, Gomes LR, Gomez R, Gómez-Sánchez R, Gomez-Puerto MC, Gomez-Sintes R, Gong Q, Goni FM, González-Gallego J, Gonzalez-Hernandez T, Gonzalez-Polo RA, Gonzalez-Reyes JA, González-Rodríguez P, Goping IS, Gorbatyuk MS, Gorbunov NV, Görgülü K, Gorojod RM, Gorski SM, Goruppi S, Gotor C, Gottlieb RA, Gozes I, Gozuacik D, Graef M, Gräler MH, Granatiero V, Grasso D, Gray JP, Green DR, Greenhough A, Gregory SL, Griffin EF, Grinstaff MW, Gros F, Grose C, Gross AS, Gruber F, Grumati P, Grune T, Gu X, Guan JL, Guardia CM, Guda K, Guerra F, Guerri C, Guha P, Guillén C, Gujar S, Gukovskaya A, Gukovsky I, Gunst J, Günther A, Guntur AR, Guo C, Guo C, Guo H, Guo LW, Guo M, Gupta P, Gupta SK, Gupta S, Gupta VB, Gupta V, Gustafsson AB, Gutterman DD, H B R, Haapasalo A, Haber JE, Hać A, Hadano S, Hafrén AJ, Haidar M, Hall BS, Halldén G, Hamacher-Brady A, Hamann A, Hamasaki M, Han W, Hansen M, Hanson PI, Hao Z, Harada M, Harhaji-Trajkovic L, Hariharan N, Haroon N, Harris J, Hasegawa T, Hasima Nagoor N, Haspel JA, Haucke V, Hawkins WD, Hay BA, 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Zeng J, Zeng JD, Žerovnik E, Zhan L, Zhang B, Zhang DD, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang H, Zhang HL, Zhang J, Zhang J, Zhang JP, Zhang KYB, Zhang LW, Zhang L, Zhang L, Zhang L, Zhang L, Zhang M, Zhang P, Zhang S, Zhang W, Zhang X, Zhang XW, Zhang X, Zhang X, Zhang X, Zhang X, Zhang XD, Zhang Y, Zhang Y, Zhang Y, Zhang YD, Zhang Y, Zhang YY, Zhang Y, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhang Z, Zhao H, Zhao L, Zhao S, Zhao T, Zhao XF, Zhao Y, Zhao Y, Zhao Y, Zhao Y, Zheng G, Zheng K, Zheng L, Zheng S, Zheng XL, Zheng Y, Zheng ZG, Zhivotovsky B, Zhong Q, Zhou A, Zhou B, Zhou C, Zhou G, Zhou H, Zhou H, Zhou H, Zhou J, Zhou J, Zhou J, Zhou J, Zhou K, Zhou R, Zhou XJ, Zhou Y, Zhou Y, Zhou Y, Zhou ZY, Zhou Z, Zhu B, Zhu C, Zhu GQ, Zhu H, Zhu H, Zhu H, Zhu WG, Zhu Y, Zhu Y, Zhuang H, Zhuang X, Zientara-Rytter K, Zimmermann CM, Ziviani E, Zoladek T, Zong WX, Zorov DB, Zorzano A, Zou W, Zou Z, Zou Z, Zuryn S, Zwerschke W, Brand-Saberi B, Dong XC, Kenchappa CS, Li Z, Lin Y, Oshima S, Rong Y, Sluimer JC, Stallings CL, Tong CK

    Autophagy   17 ( 1 )   1 - 382   2021.1( ISSN:1554-8627

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    DOI : 10.1080/15548627.2020.1797280

    PubMed

  • ERdj8 governs the size of autophagosomes during the formation process

    Yamamoto YH, Kasai A, Omori H, Takino T, Sugihara M, Umemoto T, Hamasaki M, Hatta T, Natsume T, Morimoto RI, Arai R, Waguri S, Sato M, Sato K, Bar-Nun S, Yoshimori T, Noda T, Nagata K.

    Journal of Cell Biology   219 ( 8 )   e201903127   2020.8

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    DOI : doi: 10.1083/jcb.201903127.

  • Author Correction: GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth (Scientific Reports, (2018), 8, 1, (1368), 10.1038/s41598-018-19542-4)

    Uemura, T., Kametaka, S., Waguri, S.

    Scientific Reports   10 ( 1 )   7675   2020.5( ISSN:2045-2322

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    DOI : 10.1038/s41598-020-64604-1

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  • Autophagy is involved in the sclerotic phase of systemic sclerosis

    Mori T, Tamura N, Waguri S, Yamamoto T.

    Fukushima Journal of Medical Science   66 ( 1 )   17 - 24   2020.4

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    DOI : doi: 10.5387/fms.2019-28.

  • オートファジーは全身性強皮症の硬化期に関与する(Autophagy is involved in the sclerotic phase of systemic sclerosis)

    Mori Tatsuhiko, Tamura Naoki, Waguri Satoshi, Yamamoto Toshiyuki

    Fukushima Journal of Medical Science   66 ( 1 )   17 - 24   2020.4( ISSN:0016-2590

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  • NBR1-mediated p62-liquid droplets enhance the Keap1-Nrf2 system

    Sánchez-Martín P, Sou YS, Kageyama S, Koike M, Waguri S, Komatsu M.

    EMBO Report   21 ( 3 )   e48902   2020.3

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    DOI : doi: 10.15252/embr.201948902.

  • Loss of autophagy in chondrocytes causes severe growth retardation

    Horigome Y, Ida-Yonemochi H, Waguri S, Shibata S, Endo N, Komatsu M

    Autophagy   16 ( 3 )   501 - 511   2020.3

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    DOI : doi: 10.1080/15548627.2019.1628541

  • ER-related structure mediates isolation membrane organization

    Arai R, Waguri S

    272 ( 9 )   20453 - 20458   2020.2

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  • 【オートファジー-分子機構・生物学的意義・疾患との関わり】マクロオートファジーの基礎 オートファゴソーム膜の供給 小胞体関連構造を介した隔離膜形成

    荒井 律子, 和栗 聡

    医学のあゆみ   272 ( 9 )   719 - 724   2020.2( ISSN:0039-2359

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  • Emerging roles of Golgi/endosome-localizing monomeric clathrin adaptors GGAs

    Uemura Takefumi, Waguri Satoshi

    Anatomical Science International   95 ( 1 )   12 - 21   2020.1( ISSN:1447-6959

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    DOI : doi: 10.1007/s12565-019-00505-2.

  • Loss of autophagy impairs physiological steatosis by accumulation of NCoR1

    Takahashi SS, Sou YS, Saito T, Kuma A, Yabe T, Sugiura Y, Lee HC, Suematsu M, Yokomizo T, Koike M, Terai S, Mizushima N, Waguri S, Komatsu M

    Life Science Alliance   3 ( 1 )   2019.12

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    DOI : doi: 10.26508/lsa.201900513.

  • Hyperosmotic Stress Induces Unconventional Autophagy Independent of the Ulk1 Complex

    Tamura N, Kageyama S, Komatsu M, Waguri S

    Molecular and Cellular Biology   39 ( 16 )   e00024-19   2019.7

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    DOI : doi: 10.1128/MCB.00024-19

  • Autophagy regulates lipid metabolism through selective turnover of NCoR1

    Saito T, Kuma A, Sugiura Y, Ichimura Y, Obata M, Kitamura H, Okuda S, Lee HC, Ikeda K, Kanegae Y, Saito I, Auwerx J, Motohashi H, Suematsu M, Soga T, Yokomizo T, Waguri S, Mizushima N, Komatsu M

    Nature Communications   10 ( 1 )   1567   2019.4

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    DOI : doi:10.1038/s41467-019-08829-3

  • Improved Electron Microscopy Fixation Methods for Tracking Autophagy-Associated Membranes in Cultured Mammalian Cells.

    Arai Ritsuko, Waguri Satoshi

    Methods in molecular biology   1880   211 - 221   2019

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    DOI : doi: 10.1007/978-1-4939-8873-0_13

  • 高浸透圧ストレス下におけるWIPI2の後期エンドソーム局在について

    田村直輝, 和栗聡

    日本解剖学会総会・全国学術集会講演プログラム・抄録集   124th   2019

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  • Clathrin adaptor GGA1 modulates myogenesis of C2C12 myoblasts.

    Isobe M, Lee S, Waguri S, Kametaka S

    PLoS One   13 ( 11 )   e0207533   2018.11

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  • Establishment and Characterization of a Novel Human Clear-cell Sarcoma of Soft-tissue Cell Line, RSAR001, Derived from Pleural Effusion of a Patient with Pleural Dissemination.

    Hakozaki M, Tamura H, Dobashi Y, Yoshida A, Kato K, Tajino T, Yamada H, Kaneuchi Y, Katahira K, Ezaki J, Waguri S, Konno S, Watanabe S

    Anticancer Res   38 ( 9 )   5035 - 5042   2018.9

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  • 細胞系および中枢神経系ニューロンにおけるGGAアクセサリー蛋白質p56の細胞内局在(Intracellular localization of GGA accessory protein p56 in cell lines and central nervous system neurons)

    Uemura Takefumi, Sawada Naoki, Sakaba Takao, Kametaka Satoshi, Yamamoto Masaya, Waguri Satoshi

    Biomedical Research   39 ( 4 )   179 - 187   2018.8( ISSN:0388-6107

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  • HMGB1 promotes ductular reaction and tumorigenesis in autophagy-deficient livers.

    Khambu B, Huda N, Chen X, Antoine DJ, Li Y, Dai G, Köhler UA, Zong WX, Waguri S, Werner S, Oury TD, Dong Z, Yin XM

    Journal of Clinical Investigation.   2018.5

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  • Spatiotemporal alterations of autophagy marker LC3 in rat skin fibroblasts during wound healing process.

    Asai E, Yamamoto M, Ueda K, Waguri S

    Fukushima Journal of Medical Science   64 ( 1 )   15 - 22   2018.4

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  • 創傷治癒過程でのラット皮膚線維芽細胞におけるオートファジーマーカーL3の時間的空間的変化(Spatiotemporal alterations of autophagy marker LC3 in rat skin fibroblasts during wound healing process)

    Asai Emiko, Yamamoto Masaya, Ueda Kazuki, Waguri Satoshi

    Fukushima Journal of Medical Science   64 ( 1 )   15 - 22   2018.4( ISSN:0016-2590

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  • LC3-positive puncta increase in skeletal muscle of patient-derived xenograft mice

    Hiromich Annoh, Yuu Dobashi, Naoki Tamura, Takefumi Uemura, Satoshi Waguri

    Jpn J Phys Fitness Sports Med   67 ( 1 )   99 - 105   2018.2

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  • Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild-type epidermal growth factor receptor.

    Yamaura T, Ezaki J, Okabe N, Takagi H, Ozaki Y, Inoue T, Watanabe Y, Fukuhara M, Muto S, Matsumura Y, Hasegawa T, Hoshino M, Osugi J, Shio Y, Waguri S, Tamura H, Imai JI, Ito E, Yanagisawa Y, Honma R, Watanabe S, Suzuki H

    Oncology Letters.   15 ( 2 )   1549 - 1558   2018.2

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  • GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth

    Takefumi Uemura, Satoshi Kametaka, Satoshi Waguri

    Scientific Reports   8   1368   2018.1

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  • TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis

    Ando J, Saito M, Imai JI, Ito E, Yanagisawa Y, Honma R, Saito K, Tachibana K, Momma T, Ohki S, Ohtake T, Watanabe S, Waguri S, Kono K, Takenoshita S

    Fukushima J Med Sci   19 ( 63 )   141 - 151   2017.12

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  • ジペプチダーゼ1発現が癌細胞の増殖および酸化ストレス耐性に及ぼす影響

    永井千晴, 植村武文, 和栗聡

    福島医学雑誌   67 ( 3 )   139 - 148   2017.12

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  • Metastasis of breast cancer cells to the bone, lung, and lymph nodes promotes resistance to ionizing radiation.

    Hara T, Iwadate M, Tachibana K, Waguri S, Takenoshita S, Hamada N

    Strahlentherapie und Onkologie   193 ( 10 )   848 - 855   2017.10

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  • A novel gene expression scoring system for accurate diagnosis of basaloid squamous cell carcinoma of the esophagus.

    Tada T, Honma R, Imai JI, Saze Z, Kogure M, Marubashi S, Tasaki K, Unakami M, Ezaki J, Tamura H, Nishikawa A, Hashimoto Y, Waguri S, Watanabe S, Gotoh M

    International Journal of Oncology   51 ( 3 )   877 - 886   2017.9

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  • 【Theオートファジー 研究者たちの集大成が見える最新ビジュアルテキスト】(第1章)総論 オートファジー微細形態学 メゾスケール構造の克服

    和栗 聡

    実験医学   35 ( 15 )   2483 - 2489   2017.9( ISSN:0288-5514

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  • Clinicopathological examination of dipeptidase 1 expression in colorectal cancer.

    Tachibana K, Saito M, Imai JI, Ito E, Yanagisawa Y, Honma R, Saito K, Ando J, Momma T, Ohki S, Ohtake T, Watanabe S, Waguri S, Takenoshita S

    Biomedical Report   6 ( 4 )   423 - 428   2017.4

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  • Autocrine and paracrine interactions between multiple myeloma cells and bone marrow stromal cells by growth arrest-specific gene 6 crosstalk with interleukin-6.

    Furukawa M, Ohkawara H, Ogawa K, Ikeda K, Ueda K, Shichishima-Nakamura A, Ito E, Imai JI, Yanagisawa Y, Honma R, Watanabe S, Waguri S, Ikezoe T, Takeishi Y

    J Biol Chem   2017.1

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    DOI : 10.1074/jbc.M116.733030

  • Autophagy linked FYVE (Alfy/WDFY3) is required for establishing neuronal connectivity in the mammalian brain.

    Dragich JM, Kuwajima T, Hirose-Ikeda M, Yoon MS, Eenjes E, Bosco JR, Fox LM, Lystad AH, Oo TF, Yarygina O, Mita T, Waguri S, Ichimura Y, Komatsu M, Simonsen A, Burke RE, Mason CA, Yamamoto A

    Elife   2016.9

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    DOI : 10.7554/eLife.14810

  • Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy.

    Muona M, Ishimura R, Laari A, Ichimura Y, Linnankivi T, Keski-Filppula R, Herva R, Rantala H, Paetau A, Pöyhönen M, Obata M, Uemura T, Karhu T, Bizen N, Takebayashi H, McKee S, Parker MJ, Akawi N, McRae J, Hurles ME; DDD Study., Kuismin O, Kurki MI, Anttonen AK, Tanaka K, Palotie A, Waguri S, Lehesjoki AE, Komatsu M.

    Am J Hum Genet   99 ( 3 )   683 - 694   2016.9

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    DOI : 10.1016/j.ajhg.2016.06.020

  • p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.

    Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T, Motohashi H, Waguri S, Soga T, Yamamoto M, Tanaka K, Komatsu M

    Nat Commun   2016.6

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    DOI : 10.1038/ncomms12030

  • Activation of STING requires palmitoylation at the Golgi.

    Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T

    Nat Commun   2016.6

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    DOI : 10.1038/ncomms11932

  • Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1

    Hirano S, Uemura T, Annoh H, Fujita N, Waguri S, Itoh T, Fukuda M

    Autophagy   12   312 - 326   2016

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  • Mon1-Ccz1 activates Rab7 only on late endosomes and dissociates from the lysosome in mammalian cells

    J Cell Sci   129   329 - 340   2016

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  • 医産連携による福島医薬品関連産業支援拠点化事業の現況と今後の展望

    竹之下 誠一, 大竹 徹, 和栗 聡, 渡辺 慎哉

    臨床外科   70 ( 9 )   1120 - 1124   2015.9( ISSN:0386-9857

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  • FAM83B is a novel biomarker for diagnosis and prognosis of lung squamous cell carcinoma

    Okabe N, Ezaki J, Yamaura T, Muto S, Osugi J, Tamura H, Imai J, Ito E, Yanagisawa Y, Honma R, Gotoh M, Watanabe S, Waguri S, Suzuki H

    Int J Oncol   46 ( 3 )   999 - 1006   2015.3

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  • Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells

    Eino A, Kageyama S, Uemura T, Annoh H, Saito T, Narita I, Waguri S, Komatsu M

    J Cell Sci   128   4453 - 4461   2015

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  • Somatic 15q break after long-term stable disease in acute myeloid leukemia

    Harada-Shirado K, Ikeda K, Matsumoto H, Shiga Y, Furukawa M, Takahashi H, Ohkawara H, Noji H, Hashimoto Y, Waguri S*, Watanabe S*, Ogawa K, Takeishi Y

    Clin Lymphoma Myeloma Leuk.   14 ( 2 )   e69-e72   2014.4

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  • A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane

    Uemura T*, Yamamoto M*, Kametaka A*, Sou YS, Yabashi A*, Yamada A, Annoh H*, Kametaka S, Komatsu M, Waguri S*

    Mol. Cell. Biol.   34 ( 9 )   1695 - 1706   2014

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  • 哺乳類オートファジー関連オルガネラの電子顕微鏡観察

    和栗聡, 植村武文, 山本雅哉, 矢橋あつ子

    顕微鏡   49 ( 2 )   118 - 123   2014

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  • オートファジー隔離膜近傍細管集合体の観察に用いるアルデヒド-オスミウム混合固定液の至適温度について

    矢橋あつ子, 植村武文, 和栗聡

    医学生物学電子顕微鏡技術学会誌   28 ( 1 )   9 - 11   2014

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  • Proteasome dysfunction activates autophagy and the keap1-nrf2 pathway

    Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, Komatsu M

    J Biol Chem   289 ( 36 )   24944 - 24955   2014

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  • 有糸分裂に連動した微小管依存性の中心体周囲へのエンドソーム小胞の集合(Mitosis-Coupled, Microtubule-Dependent Clustering of Endosomal Vesicles around Centrosomes)

    Takatsu Hiroyuki, Katoh Yohei, Ueda Tomoko, Waguri Satoshi, Murayama Takashi, Takahashi Senye, Shin Hye-Won, Nakayama Kazuhisa

    Cell Structure and Function   38 ( 1-2 )   31 - 41   2013.12( ISSN:0386-7196

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  • 【研究医養成】福島県立医科大学における研究医育成の取り組み

    和栗 聡, 石塚 幹太郎

    解剖学雑誌   88 ( 1-2 )   17 - 19   2013.3( ISSN:0022-7722

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  • ArfGAP3 regulates the transport of cation-independent mannose 6-phosphate receptor in the post-Golgi compartment.

    Shiba Y, Kametaka S*, Waguri S*, Presley JF, Randazzo PA

    Curr. Biol.   23 ( 19 )   1945 - 1951   2013

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  • Mitosis-coupled, microtubule-dependent clustering of endosomal vesicles around centrosomes.

    Takatsu H, Katoh Y, Waguri S*, Murayama T, Takahashi S, Shin SH, Nakayama K

    Cell Struct Funct   38 ( 1 )   31 - 41   2013

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  • The MD-PhD program at Fukushima Medical University

    Waguri S*, Ishitsuka K*

    Kaibogaku Zasshi   88   17 - 19   2013

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  • Phosphorylation of p62 activates the Keap1-Nrf2 pathway during selective autophagy.

    Ichimura Y, Waguri S*, Sou YS, Kageyama S, Hasegawa J, Ishimura R, Saito T, Yang Y, Kouno T, Fukutomi T, Hoshii T, Hirao A, Takagi K, Mizushima T, Motohashi H, Lee MS, Yoshimori T, Tanaka K, Yamamoto M, Komatsu M.

    Mol Cell.   51 ( 5 )   618 - 631   2013

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  • Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infection.

    Endo Y, Takahashi M, Iwaki D, Nakazawa N, Kodama T, Matsuzaka T, Kanno K, Liu Y, Tsuchiya K, Kawamura I, Ikawa M, Waguri S*, Wada I, Matsushita M, Schwaeble WJ, Fujita T

    J Immunol   189 ( 12 )   5860 - 5866   2012.12

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  • Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity.

    Ishibashi K, Uemura T*, Waguri S*, Fukuda M

    Mol Biol Cell   23   3193 - 3202   2012.7

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  • Rab11 regulates exocytosis of recycling vesicles at the plasma membrane.

    Takahashi S, Kubo K, Waguri S*, Yabashi A*, Shin HW, Katoh Y, Nakayama K

    J Cell Sci   2012.6

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  • Mitomycin C treatment significantly reduces central damage of islets in culture.

    Saito T*, Saito T*, Sato Y*, Ise K*, Anazawa T*, Oshibe I*, Haga J*, Yamamoto M*, Waguri S*, Gotoh M*

    Pancreas   41 ( 2 )   245 - 252   2012.3

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  • The AP-1 clathrin adaptor and CG8538/Aftiphilin are involved in the Notch signaling during eye development in Drosophila melanogaster.

    Kametaka S*, Kametaka A*, Yonekura S, Haruta M*, Takenoshita S*, Goto S, Waguri S*

    J Cell Sci   125   634 - 648   2012

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  • Visualization of TGN-endosome trafficking in mammalian and Drosophila cells

    Kametaka Satoshi, Waguri Satoshi

    Methods in Enzymology   504   255 - 271   2012

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  • Improved IsletYield and Function by Use of a Chloride Channel Blocker During Collagenase Digestion.

    Anazawa T*, Sato Y*, Saito T*, Tsuchiya T*, Kenjo A*, Kimura T*, Haga J*, Miyake M*, Waguri S*, Hazama A*, Gotoh M*

    Transplantation   2011

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  • The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice.

    Tatsumi K, Yamamoto-Mukai H, Shimizu R, Waguri S*, Sou Y.S, Sakamoto A, Taya C, Shitara H, Hara T, Chung C. H, Tanaka K, Yamamoto M, Komatsu M

    Nat Commun   2 ( 181 )   2011

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  • OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.

    Itoh T, Kanno E, Uemura T*, Waguri S*, Fukuda M

    J Cell Biol   192   839 - 853   2011

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  • Persistent activation of Nrf2 through p62 in hepatocellular carcinoma cells.

    Inami Y, Waguri S*, Sakamoto A, Kouno T, Nakada K, Hino O, Watanabe S, Andoh J*, Iwadate M*, Yamamoto M, Myung-Shik Lee M.S, Tanaka K, Komatsu M

    J Cell Biol   193   275 - 284   2011

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  • Autophagy-deficient mice develop multiple liver tumors.

    Takamura A, Komatsu M, Hara H, Sakamoto A, Kishi C, Waguri S*, Eishi Y, Hino O, Tanaka K, Mizushima N

    Genes Dev   25   795 - 800   2011

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  • The Epithelia-Specific Membrane Trafficking Factor AP-1B Controls Gut Immune Homeostasis in Mice.

    Takahashi D, Hase K, Kimura S, Nakatsu F, Ohmae M, Mandai Y, Sato T, Date Y, Ebisawa M, Kato T, Obata Y, Fukuda S, Kawamura Y. I, Dohi T, Katsuno T, Yokosuka O, Waguri S*, Ohno H

    Gastroenterology   141   621 - 632   2011

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  • Cathepsin L is highly expressed in gastrointestinal stromal tumors.

    Miyamoto K*, Iwadate M*, Yanagisawa Y*, Ito E*, Imai J*, Yamamoto M*, Sawada N*, Saito M*, Suzuki S*, Nakamura I*, Ohki S*, Saze Z*, Kogure M*, Gotoh M*, Omicronbara K*, Ohira H*, Tasaki K*, Abe M*, Goshima N, Watanabe S*, Waguri S*, Takenoshita S*

    Int J Oncol   39   1109 - 1115   2011

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  • Mechanism of statin-induced contractile dysfunction in rat cultured skeletal myofibers.

    TANAKA, Syoko*; SAKAMOTO, Kazuho*; YAMAMOTO, Masaya*; MIZUNO, Anna*; ONO, Tomoyuki*; WAGURI, Satoshi*; KIMURA, Junko *

    Journal of Pharmacological Science   114 ( 4 )   454 - 63   2010.11

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  • Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis.

    MISAKI, Ryo; MORIMATSU, Miki; UEMURA, Takefumi*; WAGURI, Satoshi*; MIYOSHI, Eiji; TANIGUCHI, Naoyuki; MATSUDA, Michiyuki; TAGUCHI, Tomohiko

    The Journal of Cell Biology   191 ( 1 )   23 - 9   2010.9

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  • The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.

    KOMATSU, Masaaki; KUROKAWA, Hirofumi; WAGURI, Satoshi*; TAGUCHI, Keiko; KOBAYASHI, Akira; ICHIMURA, Yoshinobu; SOU, Yu-Shin; UENO, Izumi; SAKAMOTO, Ayako; TONG, Kit I; KIM, Mihee; NISHITO, Yasumasa; IEMURA, Shun-ichiro; NATSUME, Tohru; UENO, Takashi; KOMINAMI, Eiki; MOTOHASHI, Hozumi; TANAKA, Keiji; YAMAMOTO, Masayuki

    Nature Cell Biology   12 ( 3 )   213 - 223   2010.3

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  • Siglec-7 mediates nonapoptotic cell death independently of its immunoreceptor tyrosine-based inhibitory motifs in monocytic cell line U937.

    MITSUKI, Motoaki; NARA, Kiyomitsu; YAMAJI, Toshiyuki; Enomoto, Ayako; KANNO, Mayumi; YAMAGUCHI, Yoshiki; YAMADA, Akane*; WAGURI, Satoshi*; HASHIMOTO, Yasuhiro

    Glycobiology   20 ( 3 )   395 - 402   2010.3

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  • Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster.

    KAMETAKA, Satoshi*; SAWADA, Naoki*; BONIFACINO, Juan S; WAGURI, Satoshi*

    Journal of Cell Science   123 ( Pt3 )   460 - 471   2010.2

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  • Measurement of autophagy in cells and tissues

    Tanida Isei, Waguri Satoshi

    Methods in Molecular Biology   648   193 - 214   2010

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  • Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response.

    Nature   462 ( 7270 )   226 - 3   2009.11

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  • Involvement of Na(+)/Ca(2+) exchanger in migration and contraction of rat cultured tendon fibroblasts.

    J Physiol.   587   5345 - 59   2009.11

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  • Primary sensory neuronal expression of SLURP-1, an endogenous nicotinic acetylcholine receptor ligand.

    Neurosci Res   2009.5

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  • Three Homologous ArfGAPs Participate in Coat Protein I-mediated Transport.

    J Biol Chem   284 ( 20 )   13948 - 57   2009.5

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  • Participation of autophagy in the initiation of graft dysfunction after rat liver transplantation.

    Autophagy   5 ( 3 )   2009.4

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  • Biochemical and morphological detection of inclusion bodies in autophagy-deficient mice

    Waguri Satoshi, Komatsu Masaaki

    Methods in Enzymology   453   181 - 196   2009

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    DOI : doi: 10.1016/S0076-6879(08)04009-3

  • The Atg8 Conjugation System Is Indispensable for Proper Development of Autophagic Isolation Membranes in Mice

    Sou YS, Waguri S, Iwata JI, Ueno T, Fujimura T, Hara T, Sawada N, Yamada A, Mizushima N, Uchiyama Y, Kominami E, Tanaka K, Komatsu M

    Molecular Biology of the Cell   19   4762 - 4775   2008.11

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  • Human RME-8 Is Involved in Membrane Trafficking through Early Endosome

    Fujibayashi A, Taguchi T, Misaki R, Ohtani M, Dohmae N, Takio K, Yamada M, Gu J, Yamakami M, Fukuda M, Waguri S, Uchiyama Y, Yoshimori T, Sekiguchi K.

    Cell Struct Funct   33 ( 1 )   35 - 50   2008.2

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  • Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury.

    Koike M, Shibata M, Tadakoshi M, Gotoh K, Komatsu M, Waguri S, Kawahara N, Kuida K, Nagata S, Kominami E, Tanaka K, Uchiyama Y.

    Am J Pathol   172 ( 2 )   454 - 469   2008.1

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  • Specific depletion of GGA2 causes cathepsin D missorting in HeLa cells.

    Hida T, Ikeda H, Kametaka S, Akazawa C, Kohsaka S, Ebisu S, Uchiyama Y, Waguri S. 2007 Dec;70(5):303-301

    Arch Histol Cytol.   70 ( 5 )   303 - 312   2007.12

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  • Rab-small GTPases are involved in fluvastatin and pravastatin-induced vacuolation in rat skeletal myofiber

    FASEB J   21 ( 14 )   4087 - 4094   2007.12

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  • Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons

    Komatsu M, Ueno T, Waguri S, Uchiyama Y, Kominami E, Tanaka K

    Cell Death and Differentiation   14   887 - 894   2007.3

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  • C-terminal Src kinase controls development and maintenance of mouse squamous epithelia

    Yagi R, Waguri S, Sumikawa Y, Nada S, Oneyama C, Itami S, Schmedt C, Uchiyama Y, Okada M

    EMBO J   26 ( 5 )   1234 - 1244   2007.3

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  • Homeostatic Levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

    Komatsu M, Waguri S, Koike M, Sou Y, Ueno T, Hara T, Mizushima N, Iwata J, Ezaki J, Murata S, Hamazaki J, Nishito Y, Iemura S, Natsume T, Yanagawa T, Uwayama J, Warabi E, Yoshida H, Ishii T, Kobayashi A, Yamamoto M, Yue Z, Uchiyama Y, Kominami E, Tanaka K

    Cell   131 ( 1 )   149 - 1163   2007

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  • Uncoupling protein 2 negatively regulates neurite extensions in PC12h cells

    Yamada S, Isojima Y, Kanamori S, Waguri S, Uchiyama Y, Nagai K.

    Neurosci Lett   410 ( 2 )   110 - 114   2006.12

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  • The luminal domain participates in the endosomal trafficking of the cation-independent mannose 6-phosphate receptor.

    Waguri S, Tomiyama Y, Ikeda H, Hida T, Sakai N, Taniike M, Ebisu S, Uchiyama Y.

    Exp. Cell Res.   312 ( 20 )   4090 - 4107   2006.12

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  • Loss of autophagy in the central nervous system causes neurodegeneration in mice.

    Komatsu M, Waguri S, Chiba T, Murata S, Iwata J, Tanida I, Ueno T, Koike M, Uchiyama Y, Kominami E, Tanaka K.

    Nature   441 ( 7095- )   880 - 884   2006.6

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  • Gene transfer of hepatocyte growth factor gene improves learning and memory in the chronic stage of cerebral infarction

    Shimamura M, Sato N, Waguri S, Uchiyama Y, Hayashi T, Iida H, Nakamura T, Ogihara T, Kaneda Y, Morishita R.

    Hypertension   47 ( 4 )   742 - 751   2006.4

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  • Participation of autophagy in storage of lysosomes in neurons from mouse models of neuronal ceroid-lipofuscinoses (Batten disease).

    Koike M, Shibata M, Waguri S, Yoshimura K, Tanida I, Kominami E, Gotow T, Peters C, von Figura K, Mizushima N, Saftig P, Uchiyama Y.

    Am J Pathol   167 ( 6 )   1713 - 1728   2005.12

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  • Roles of ARFRP1 (ADP-ribosylation factor-related protein 1) in post-Golgi membrane trafficking.

    Shin HW, Kobayashi H, Kitamura M, Waguri S, Suganuma T, Uchiyama Y, Nakayama K.

    J Cell Sci   118   4039 - 4048   2005.9

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  • Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice.

    Komatsu M, Waguri S, Ueno T, Iwata J, Murata S, Tanida I, Ezaki J, Mizushima N, Ohsumi Y, Uchiyama Y, Kominami E, Tanaka K, Chiba T.

    J Cell Biol   169 ( 3 )   425 - 434   2005.5

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  • Human CHMP6, a myristoylated ESCRT-III protein, interacts directly with an ESCRT-II component EAP20 and regulates endosomal cargo sorting.

    Yorikawa C, Shibata H, Waguri S, Hatta K, Horii M, Katoh K, Kobayashi T, Uchiyama Y, Maki M.

    Biochem J   387   17 - 26   2005.4

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  • Insights into the phosphoregulation of beta-secretase sorting signal by the VHS domain of GGA1.

    Shiba T, Kametaka S, Kawasaki M, Shibata M, Waguri S, Uchiyama Y, Wakatsuki S.

    Traffic   5 ( 6 )   437 - 438   2004.6

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  • Novel therapeutic strategy to treat brain ischemia: overexpression of hepatocyte growth factor gene reduced ischemic injury without cerebral edema in rat model.

    Shimamura M, Sato N, Oshima K, Aoki M, Kurinami H, Waguri S, Uchiyama Y, Ogihara T, Kaneda Y, Morishita R.

    Circulation   109 ( 3 )   424 - 431   2004.1

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  • Early-phase redistribution of the cation-independent mannose 6-phosphate receptor by U18666A treatment in HeLa cells

    Cell Tissue Res   317   253 - 264   2004

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  • Visualization of TGN to endosome trafficking through fluorescently labeled MPR and AP-1 in living cells

    Mol Biol Cell   14   142 - 155   2003

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    Publishing type:Research paper (other academic)  

  • Predominant expression of the short form of GGA3 in human cell lines and tissues

    Biochem Biophys Res Commun   306   687 - 692   2003

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  • Dominant-negative mutant of BIG2, an ARF-guanine nucleotide exchange factor, specifically affects membrane trafficking from the trans-Golgi network through inhibiting membrane association of AP-1 and GGA coat proteins

    294   254 - 260   2002

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    Publishing type:Research paper (other academic)  

  • Different distribution patterns of the two mannose 6-phosphate receptors in rat liver

    Kohmura M, Kanamori S, Watanabe T, Ohsawa Y, Koike M, Tomiyama Y, Wakasugi M, Kominami E, Uchiyama Y

    J. Histochem. Cytochem.   49   1397 - 1405   2001

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  • Bidirectional trafficking between the trans-Golgi network and the endosomal/lysosomal system

    113   2093 - 2101   2000

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  • The induction of autophagic vacuoles and the unique endocytic compartments, C-shaped multivesicular bodies, in GH4C1 cells after treatment with 17beta-estradiol, insulin and EGF

    Acta. Histochem. Cytochem.   62   423 - 34   1999

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    Publishing type:Research paper (other academic)  

  • Overexpression of Cation-Dependent Mannose 6-Phosphate Receptor Prevents Cell Death Induced by Serum Deprivation in PC12 Cells

    Biochem. Biophys. Res. Commun.   251   204 - 208   1998

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    Publishing type:Research paper (other academic)  

  • Immunocytochemical localization of lysosomal cysteine and aspartic proteinases, and ubiquitin in rat epidermis

    The Journal of Histchemistry and Cytochemistry   60   275 - 287   1997

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    Publishing type:Research paper (other academic)  

  • Cysteine proteinases in GH&lt;sub&gt;4&lt;/sub&gt;C&lt;sub&gt;1&lt;/sub&gt; cells, a rat pituitary tumor cell line, are secreted by the constitutive and regulated secretory pathways

    67   308 - 318   1995

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    Publishing type:Research paper (other academic)  

  • Cell and tissue distribution of lysosomal cysteine proteinases, cathepsins B, H, and L, and their biological roles

    Acta. Histochem. Cytochem.   27   351 - 372   1994

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    Publishing type:Research paper (other academic)  

  • Cysteine proteinases in rat parathyroid cells with special reference to their correlation with parathyroid hormone(PTH)in storage granules

    The Journal of Histochemistry and Cytochemistry   41 ( 2 )   273 - 282   1993

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    Publishing type:Research paper (other academic)  

  • Coexistence of renin and cathepsin B in secretory granules of granular duct cells in male mouse submandibular gland

    41 ( 3 )   433 - 438   1993

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    Publishing type:Research paper (other academic)  

  • Variations in immunoreactivity for phenobarbital-and 3- methylcholanthrene-inducible cytochromes p-450, and NADPH- cytochrome P-450 reductase in rat liver over twenty-four hours.

    97   1992

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    Publishing type:Research paper (other academic)  

  • Variations in immunoreactivity of angiotensinogen and cathepsins B and H in rat hepatocytes over 24 hours.

    The American journal of Anatomy   187   1990

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  • Immunocytochemical localization of angiotensinogen and cathepsins B, H, and L in rat hepatocytes, with special referenece to degradation of angiotensinogen in lysosomes after colchicine

    37   1899 - 1911   1989

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Books

  • ウィーター 図説で学ぶ機能組織学 原著第6版

    後藤 薫, 和栗 聡

    エルゼビア・ジャパン株式会社  2018.7 

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    Language:Japanese   Book type:Textbook, survey, introduction

  • 蛋白質核酸酵素「メンブレントラフィックの奔流」

    (ライブセルイメージングによる輸送キャリヤーの同定)

    共立出版  2008.12 

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    Responsible for pages:2292-2294   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:東京  

  • 電子顕微鏡を用いた組織細胞化学

    Surgery Frontier  2006 

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    Responsible for pages:75-79   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:  

  • 凍結超薄切片を用いた免疫電顕法

    Surgery Frontier  2006 

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    Responsible for pages:80-84   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:  

  • 組織細胞化学2005

    日本組織細胞化学会(蛍光タンパク質を用いた生細胞観察法)

    学際企画  2005 

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    Responsible for pages:149-158   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:東京  

  • 組織細胞化学2004

    日本組織細胞化学会(GFPを用いた標的タンパク質の発現とその観察)

    学際企画  2004 

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    Responsible for pages:279-287   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:東京  

  • 初めてでもできる共焦点顕微鏡活用プロトコール

    高田邦昭(FRAPによるGFP融合分子の解析)

    羊土社  2004 

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    Responsible for pages:127-132   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:東京  

  • GFPが変えた細胞内小胞輸送の世界

    電子顕微鏡  2003 

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    Responsible for pages:161-165   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:  

  • 第15回博多シンポジウムテキスト

    九州臨床検査技師会(リソームシステムと細胞死)

    その他の出版機関  2002 

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    Responsible for pages:23-30   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:福岡  

  • オートファジーと細胞死

    医学のあゆみ  2002 

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    Responsible for pages:309-313   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:  

  • ライソゾームシステインプロテアーゼの局在の多様性

    生体の科学  1995 

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    Responsible for pages:243-249   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:和栗 聡   Publication place:  

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Presentations

  • 顕微科学から迫る細胞内分解最先端

    日本顕微鏡学会 第66回シンポジウム   2023.11  

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    Event date: 2023.11

  • ATG9Aはオートファジー非依存的にクラミジア増殖に関与する

    第128回日本解剖学会総会・全国学術総会  

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    Event date: 2023.3

  • クラスリンアダプターAP-1複合体によるEGFR発現調節機構

    第128回日本解剖学会総会・全国学術総会  

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    Event date: 2023.3

  • 高浸透圧ストレス下で形成される非膜性オルガネラの解析

    第128回日本解剖学会総会・全国学術総会  

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    Event date: 2023.3

  • Characterization of p62-body induced under hyperosmotic stress in mammalian cells

    The 10th International Symposium on Autophagy  

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    Event date: 2022.10

  • Non-autophagic function of ATG9A is involved in the proliferation of Chlamydia trachomatis

    The 10th International Symposium on Autophagy  

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    Event date: 2022.10

  • 高浸透圧ストレス下で形成される非膜性オルガネラの比較解析

    第74回日本細胞生物学会大会   2022.6  

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    Event date: 2022.6 - 2023.6

  • 高浸透圧ストレス下で形成される非膜性オルガネラの微細構造解析

    日本顕微鏡学会第78回学術講演会  

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    Event date: 2022.5 - 2023.5

  • Ultrastructural analysis on the process of isolation membrane formation during piecemeal mitophagy

    2022.5  

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    Event date: 2022.5 - 2023.5

  • 膜交通によるEGFRの寿命調節機構

    日本顕微鏡学会第78回学術講演会  

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    Event date: 2022.5 - 2023.5

  • UBXD8flox/flox・CNP1-Creマウスの解析

    日本顕微鏡学会第78回学術講演会  

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    Event date: 2022.5 - 2023.5

  • 哺乳類細胞におけるSQSTM1/p62液滴の形成と分解

    第127回日本解剖学会総会・全国学術総会   2022.3  

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    Event date: 2022.3 - 2023.3

  • オリゴデンドロサイト特異的UBXD8ノックアウトマウスの解析

    第127回日本解剖学会総会・全国学術総会  

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    Event date: 2022.3 - 2023.3

  • 高浸透圧ストレスに応答した非膜性オルガネラの形成・分解機序

    第127回日本解剖学会総会・全国学術総会  

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    Event date: 2022.3 - 2023.3

  • Roles of recycling endosome-localized clathrin adaptors AP-1 and GGA2 in regulation of cell surface expression of EGFR for cell growth

    2022.3  

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    Event date: 2022.3 - 2023.3

  • ピースミールマイトファジー隔離膜形成プロセスの微細形態学的解析

    第44回日本分子生物学会年会  

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    Event date: 2021.12

  • クラミジア感染細胞におけるAtg9A機能解析

    第94回日本生化学大会  

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    Event date: 2021.11

  • Recycling endosome-localized clathrin adaptors AP-1 and GGA2 regulate cell surface expression of EGFR for cell growth

    第80回日本癌学会学術総会  

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    Event date: 2021.10

  • Recycling endosome-localized clathrin adaptors AP-1 and GGA2 regulate cell surface expression of EGFR for cell growth

    2021.10  

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    Event date: 2021.9 - 2021.10

  • ピースミールマイトファジー隔離膜構築プロセスの電子顕微鏡解析

    日本解剖学会第67回東北・北海道連合支部学術集会  

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    Event date: 2021.9

  • Ultrastructural analysis on the process of isolation membrane formation during piecemeal mitophagy

    第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会 合同大会  

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    Event date: 2021.3

  • オートファジー関連分子群によるクラミジア感染制御

    第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会 合同大会  

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    Event date: 2021.3

  • Endosome-localized clathrin adaptors AP-1 and GGA2 regulate cell surface expression of EGFR for cell growth

    第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会 合同大会  

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    Event date: 2021.3

  • 高浸透圧ストレス下における非膜性オルガネラの形成と分解

    第66回日本解剖学会 東北・北海道連合支部学術集会  

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    Event date: 2020.9

  • 高浸透圧ストレス変動に応答したp62顆粒およびストレス顆粒の形成・消失機序

    第72回日本細胞生物学会大会  

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    Event date: 2020.6

  • 部分的マイトファジーにおける隔離膜生成・伸張過程の微細構造解析

    第125回日本解剖学会総会・全国学術大会  

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    Event date: 2020.3

  • Isolation membrane-associated tubules: A key organelle for the formation of autophagosome

    Scientific and Practical Conference with International participation  

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    Event date: 2019.10

  • Two Decades of Medical Education Reform in Japan

    Continuing professional medical education and certification of medical workers: Today and tomorrow  

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    Event date: 2019.4

  • マイトファジー隔離膜の微細構造解析

    第124回日本解剖学会総会・全国学術大会  

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    Event date: 2019.3

  • CLEM解析によるマイトファジー隔離膜のイメージング

    第41回日本分子生物学会年会  

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    Event date: 2018.11

  • Mitophagic isolation membrane visualized by CLEM analysis

    XXVI International Symposium on Morphological Sciences  

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    Event date: 2018.7

  • ゴルジ‐エンドソーム局在型クラスリンアダプターによるEGFRの新規寿命調節機構

    第123回日本解剖学会総会全国学術集会  

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    Event date: 2018.3

  • オートファジ―関連遺伝子Atg2の生理機能解析

    第123回日本解剖学会総会  

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    Event date: 2018.3

  • Autophagy in hyperosmotic stress conditions

    A3 conference on Autophagy  

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    Event date: 2018.3

  • オートファジー関連遺伝子Atg2の生理機能

    第123回日本解剖学会総会全国学術集会  

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    Event date: 2018.3

  • オートファジーの形態学 : 電顕と免疫組織

    第33回Wakoワークショップ  

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    Event date: 2017.11

  • Golgi/endosome-localized clathrin adaptor protein GGA2 sustains cell growth by preventing EGFR degradation

    第76回日本癌学会学術総会  

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    Event date: 2017.9

  • 哺乳類細胞オートファゴソーム形成過程における膜構造変化の解析

    日本解剖学会 題63回東北・北海道連合支部学術集会  

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    Event date: 2017.9

  • オートファジー研究の現状と皮膚科学における可能性

    第81回日本皮膚科学会東部支部学術大会  

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    Event date: 2017.9

  • Ultrastructure of Autophagy by Electron Microscopy

    The 25th International Symposia on Morphological Sciences  

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    Event date: 2017.7

  • オートファジー研究から小児成長を考える

    第18回東北小児成長フォーラム  

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    Event date: 2017.7

  • Involvement of Golgi/endosome-localized clathrin adaptor proteins GGAs in EGFR degradation

    第69回日本細胞生物学会大会  

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    Event date: 2017.6

  • Phenotypic analysis of mice defective in Atg2A/B 

    第69回日本細胞生物学会大会  

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    Event date: 2017.6

  • 浸透圧ストレス誘導性オートファジーの分子機構の解明

    第69回日本細胞生物学会大会  

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    Event date: 2017.6

  • ゴルジ‐エンドソーム局在型クラスリンアダプターGGA2は上皮成長因子受容体(EGFR)の安定化を介して腫瘍増殖を促進する

    第122回日本解剖学会総会全国学術集会  

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    Event date: 2017.3

  • 構造化照明法によるオートファジー隔離膜の超解像顕微鏡解析

    第57回日本組織細胞化学会総会・学術集会  

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    Event date: 2016.9

  • オートファジー関連分子WIPI-1、WIPI-2 の浸透圧ストレスへの関与

    第62回日本解剖学会 東北・北海道連合支部学術集会  

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    Event date: 2016.9

  • オートファジー関連分子WIPI-1、WIPI-2 の浸透圧ストレスへの関与

    第68回日本細胞生物学会大会  

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    Event date: 2016.6

  • Sqstm1-GFP knock-in mice reveal dynamic action of Sqstm1 / p62 during autophagy and stress-conditions in living cells

    第121回日本解剖学会総会全国学術集会  

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    Event date: 2016.3

  • 先端顕微鏡技術が紐解くオートファジー分解機構

    第121回日本解剖学会総会全国学術集会  

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    Event date: 2016.3

  • 先端的電顕解析が紐解くオートファジーの発動形態

    第16回Bio電顕セミナー  

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    Event date: 2016.3

  • オートファジー隔離膜の形成過程に関与する新規細管集合体

    第56回日本組織細胞化学会総会・学術集会  

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    Event date: 2015.10

  • 上皮成長因子受容体の分解と細胞増殖におけるGGA分子の機能

    第74回日本癌学会学術総会  

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    Event date: 2015.10

  • ラット顔面神経切断縫合モデルにおけるクラスリン小胞輸送関連タンパク質の動態変化

    日本解剖学会 第61回東北・北海道連合支部学術集会  

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    Event date: 2015.8

  • Ultrastructural analyses of the formation of autophagic isolation membrane in mammalian cells.

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    Event date: 2015.3

  • Functional analyses of dipeptidase-1 (DPEP1) using a colon / gastric cancer-derived cell line, HCC56

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    Event date: 2015.3

  • ラット顔面神経切断縫合モデルにおけるクラスリン小胞輸送関連タンパク質の動態変化

    日本解剖学会 第61回東北・北海道連合支部学術集会  

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    Event date: 2015

  • A cluster of isolation membrane-associated tubules represents a part of omegasome during autophagosome formation.

    2014 Northeastern Asian Symposium on Autophagy  

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    Event date: 2014.12

  • A cluster of isolation membrane-associated tubules represents a part of omegasome during final steps of autophagosome formation.

    ASCB Annual Meeting  

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    Event date: 2014.12

  • ヒト胃癌/大腸癌細胞株におけるDipeptidase-1の機能、局在解析

    第73回日本癌学会学術総会  

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    Event date: 2014.9

  • 上皮成長因子受容体の恒常的分解と細胞増殖に関与するGGA分子の解析

    日本解剖学会 第60回東北・北海道連合支部学術集会  

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    Event date: 2014.9

  • オートファジー隔離膜の形成過程には小胞体由来細管集合体が関与する

    第14回日本蛋白質科学会年会  

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    Event date: 2014.6

  • オートファジー隔離膜の形成過程には小胞体由来細管集合体が関与する

    第66回日本細胞生物学会大会  

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    Event date: 2014.6

  • オートファジー研究が切り拓く電顕ワールド

    医学生物学電子顕微鏡技術学会 第30回学術講演会および総会  

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    Event date: 2014.5

  • オートファジー隔離膜の形成過程には小胞体由来細管集合体が関与する

    第119回日本解剖学会総会・全国学術集会  

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    Event date: 2014.3

  • マウスにおけるクラスリンアダプターGGAの組織分布解析

    第119回日本解剖学会総会・全国学術集会  

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    Event date: 2014.3

  • ライソゾーム病関連因子のモデル生物を用いた解析

    第119回日本解剖学会総会・全国学術集会  

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    Event date: 2014.3

  • Tissue and cellular distribution of the clathrin adaptor accessory protein p56 in mouse tissues

    XXIII International Symposium on morphological Science 2013  

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    Event date: 2013.9

  • Autophagy is involved in muscle wasting in tumor-bearing cachectic mice.

    XXIII International Symposium on morphological Science 2013  

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    Event date: 2013.9

  • Functional characterization of lysosomal enzyme receptor protein (LERP) in Drosophila.

    XXIII International Symposium on morphological Science 2013  

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    Event date: 2013.9

  • Autophagosme precursor structures and p62-aggregates associated with autophagy deficiency.

    XXIII International Symposium on morphological Science 2013  

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    Event date: 2013.9

  • ゴルジ局在型クラスリンアダプターGGAの局在解析

    日本解剖学会第59回東北・北海道連合支部学術集会  

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    Event date: 2013.9

  • 担癌悪液質モデルマウスの骨格筋萎縮過程におけるオートファジーの関与

    日本解剖学会第59回東北・北海道連合支部学術集会  

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    Event date: 2013.9

  • Morphological aspects of the biogenesis of ER-derived autophagic isolation membranes.

    International Symposium Anatomical Science for advance in health and clinical therapy 2013 (ASahct 2013)  

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    Event date: 2013.8

  • Autophagy is involved in muscle wasting in tumor-bearing cachectic mice.

    International Symposium Anatomical Science for advance in health and clinical therapy 2013 (ASahct 2013)  

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    Event date: 2013.8

  • ショウジョウバエを用いたライソゾーム蛋白質輸送機構の解析

    第65回日本細胞生物学会大会  

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    Event date: 2013.6

  • 上皮成長因子受容体の細胞内分解に関与するゴルジ‐エンドソーム局在型クラスリンアダプター分子の解析

    第65回日本細胞生物学会大会  

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    Event date: 2013.6

  • オメガソームの微細構造解析

    日本顕微鏡学会 第69回学術講演会  

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    Event date: 2013.5

  • ライソゾーム酵素局在化に関わる選別受容体Lerpの生理機能解析

    第118回日本解剖学会総会・全国学術集会  

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    Event date: 2013.3

  • ラット顔面神経切断縫合モデルにおけるクラスリンアダプター修飾タンパク質p56の局在発現解析

    第118回日本解剖学会総会・全国学術集会  

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    Event date: 2013.3

  • ゴルジ体局在型クラスリンアダプターGGAの機能制御機構の解析

    118回日本解剖学会総会・全国学術集会  

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    Event date: 2013.3

  • オメガソームの微細構造解析および隔離膜・小胞体との関係

    第118回日本解剖学会総会・全国学術集会  

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    Event date: 2013.3

  • ヒト大腸癌由来細胞株におけるDipeptidase-1(DPEP1)の局在解析

    第118回日本解剖学会総会・全国学術集会  

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    Event date: 2013.3

  • Fine sturucture of omegasome and its relationship to the ER and isolation membrane.

    The 6th International Symposium on Autophagy  

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    Event date: 2012.10

  • ヒト大腸癌細胞株におけるDipeptidase-1の機能局在解析

    日本解剖学会第58回東北・北海道連合支部学術集会  

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    Event date: 2012.9

  • 電子線トモグラフィー法を用いたオートファゴソーム最終形成過程の微細構造解析

    日本解剖学会第58回東北・北海道連合支部学術集会  

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    Event date: 2012.9

  • Identification of a novel transforming gene encoding an E3 ubiquitin ligase-like protein.

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    Event date: 2012.9

  • Establishment of collagen gel 3D culture as a screening system for novel breast cancer oncogenes involved in invasion.

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    Event date: 2012.9

  • Oncogenic function of retinoic acid receptor alpha(RARA) as an epithelial-mesenchymal transition (EMT)-inducing factor.

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    Event date: 2012.9

  • Morphological aspects of the biogenesis of ER-derived autophagic isolation membranes.

    14th International Congress of Histochemistry and Cytochemistry  

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    Event date: 2012.8

  • AP-1複合体を介したNotch輸送調節機構の解析.

    日本生化学会 第84回大会  

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    Event date: 2011.9

  • 培養細胞を用いたβklothoの動態・局在解析

    日本解剖学会第57回東北・北海道連合支部学術学会  

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    Event date: 2011.9

  • 上皮成長因子受容体の細胞内分解に関与するゴルジ-エンドソーム局在型クラスリンアダプター分子の解析

    日本解剖学会第57回東北・北海道連合支部学術学会  

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    Event date: 2011.9

  • ショウジョウバエを用いたクラスリンアダプターの機能解析

    第56回日本解剖学会 東北・北海道連合支部学術集会  

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    Event date: 2010.9

  • Atg3欠損マウス線維芽細胞株におけるオメガソームマーカーDFCP1の局在解析

    第56回日本解剖学会 東北・北海道連合支部学術集会  

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    Event date: 2010.9

  • GIST-specific markers identified by comprehensive gene expression profiles

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    Event date: 2010.9

  • A prognostic marker set of Japanese breast cancer predicted by comprehensive gene expression analysis

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    Event date: 2010.9

  • Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster

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    Event date: 2010.6

  • Functional characterization of protein-sorting machineries at the trans-Golgi network in Drosophila melanogaster

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    Event date: 2010.5

  • Atg3欠損マウス線維芽細胞株で見られたオートファゴソーム様構造の形態学的解析

    第115回日本解剖学会全国学術集会  

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    Event date: 2010.3

  • マウス組織におけるGGAアクセサリータンパク質,p56,の発現分布解析

    第115回日本解剖学会全国学術集会  

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    Event date: 2010.3

  • ラット皮膚創傷治癒過程におけるMAP1LC3の免疫組織学的動態解析

    第115回日本解剖学会全国学術集会  

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    Event date: 2010.3

  • リソソーム酵素の選別輸送メカニズムの解析

    第115回日本解剖学会全国学術集会  

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    Event date: 2010.3

  • Discovery of nobel regulation of Nrf2-Keap1 system by a selective autophagy substrate,p62

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    Event date: 2009.6

  • Three Homologous ArfGAPs Participate in COPI-mediated Transport

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    Event date: 2009.6

  • 高等動物におけるオートファジーの生理機能と隔離膜成熟機構

    第114回日本解剖学会全国学術集会  

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    Event date: 2009.3

  • ショウジョウバエ細胞を用いたクラスリンアダプターの機能解析

    第114回日本解剖学会全国学術集会  

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    Event date: 2009.3

  • GFP-MPR融合タンパク質を安定に発現するHeLa細胞を用いたGGA3の機能解析

    第114回日本解剖学会全国学術集会  

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    Event date: 2009.3

  • Different phenotypes caused by specific depletion of GGA1, 2, or 3 in HeLa cells

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    Event date: 2008.6

  • Different phenotypes caused by specific depletion of GGA1, 2, or 3 in HeLa cells

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    Event date: 2008.3

  • The luminal domain paticipates in the endosomal trafficking of the cation-independent mannose 6-phosphate receptor

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    Event date: 2007.5

  • 光学顕微鏡で捉えるTGN-エンドソーム間のリサイクリング輸送

    日本顕微鏡学会 第63回学術講演会  

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    Event date: 2007.5

  • カチオン非依存性マンノース6リン酸受容体の細胞質外ドメインはエンドソームにおける輸送動態に関与する

    第112回日本解剖学会学術集会  

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    Event date: 2007.3

  • The luminal domain paticipates in the endosomal trafficking of the cation-independent mannose 6-phosphate receptor

    The 16th International Microscopy Congress  

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    Event date: 2006.9

  • 単量体クラスリンアダプタータンパク質GGA2の分子特性について

    第111回日本解剖学会学術集会  

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    Event date: 2006.3

  • TGN-エンドソームにおけるGGAの役割

    第111回日本解剖学会学術集会  

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    Event date: 2006.3

▼display all

Research Projects

  • 粘性からみた細胞内液滴の分子・形態解析

    Grant number:23H02660  2023.4 - 2026.3

    基盤研究(B)

    和栗 聡, 田村 直輝, 鈴木 倫毅

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    Grant amount:\18720000 ( Direct Cost: \14400000 、 Indirect Cost:\4320000 )

  • p62変異による液-液相分離異常の微細形態とその分子基盤

    2020.4 - 2023.3

    和栗 聡、田村 直輝

  • 選択的オートファジーによる細胞制御

    2019.4 - 2024.3

    小松 雅明、和栗 聡

  • 癌細胞増殖を制御するクラスリンアダプター依存性分解カスケード

    2017.9 - 2020.5

    和栗 聡、和田 郁夫, 丸橋 繁, 河野 浩二, 大竹 徹, 池添 隆之, 小川 一英, 鈴木 弘之, 橋本 優子

  • 細胞増殖因子の定常発現を制御する新機構:クラスリンアダプター依存性分解カスケード

    2017.5 - 2019.10

    和栗 聡、植村 武文

  • Experiment of autophagy in keloidal collagen

    Grant number:17K17023  2017.4 - 2019.3

    Grant-in-Aid for Young Scientists (B)

    Masaru Horikiri, Waguri Satoshi

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    Grant amount:\1820000 ( Direct Cost: \1400000 、 Indirect Cost:\420000 )

    The autophagy refers to a phenomenon to break down a cell ingredient of the self into in lysosome. It was reported recently that an autophagy-lysosomal system was affected in a fibroblast of the granulation tissues of the rat wound healing model. The condition of a patient caused by the fibroblastic abnormality increase includes a keloid. I used NRK cell derived from a rat fibroblast for the purpose of investigating sounding out and a cell growth factor, participation in autophagy of the differentiation factor thoroughly, and the researcher analyzed a cause of the increase of the number of the LC3-positive granules in the mammalian fibroblast about an effect of bFGF and transforming growth factor-beta in consideration of the possibility that abnormality of autophagy in the fibroblast caused a keloid.

  • オートファジーの機能形態学的基盤-隔離膜生成機構の解明に向けて-

    2015.4 - 2018.3

    和栗 聡、亀高 諭, 植村 武文, 田村 直輝, 荒井 律子, 安納 弘道

  • 次世代がん研究シーズ戦略的育成プログラム「転写機能をターゲットとした創薬」(細胞内ストレス応答機構を標的とした分子標的薬の開発)

    2014.12 - 2016.3

  • オートファジー選択的基質による細胞制御とその病態生理

    2013.4 - 2018.3

    小松 雅明、和栗 聡

  • リンパ節転移を予測する新規大腸癌マーカーの機能解析

    2012.4 - 2015.3

    竹之下 誠一、中村 泉、和栗 聡

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