Meta-iodobenzylguanidine (MIBG) is an analog of norepinephrine and guanethidine, and MIBG scintigraphy is useful to diagnose tumors of the sympathetic nervous system, such as pheochromocytoma, paraganglioma, and neuroblastoma. To date, there have been few reports of MIBG accumulation in gastrointestinal stromal tumors (GISTs), so the mechanism and frequency of MIBG accumulation in GISTs are unknown. Herein, we report and discuss three cases of GIST in which scintigraphy that was performed to exclude pheochromocytoma showed MIBG accumulation.
Abstract/References
Three cases of gastrointestinal stromal tumors with metaiodobenzylguanidine (MIBG) accumulation
Honami Kobiyama, Shiro Ishii, Yumi Saito, Natsumi Kawamoto, Shigeyasu Sugawara, Hiroshi Ito
Author information
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Honami Kobiyama
Department of Radiology and Nuclear Medicine, Fukushima Medical University
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Shiro Ishii
Department of Radiology and Nuclear Medicine, Fukushima Medical University
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Yumi Saito
Department of Radiology and Nuclear Medicine, Fukushima Medical University
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Natsumi Kawamoto
Department of Radiology and Nuclear Medicine, Fukushima Medical University
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Shigeyasu Sugawara
Department of Radiology and Nuclear Medicine, Fukushima Medical University
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Hiroshi Ito
Department of Radiology and Nuclear Medicine, Fukushima Medical University
Abstract
References
5. Dellen DV, Mitu-Pretorian OM, Augustine T. Aberrant I-123 MIBG uptake in a gastrointestinal stromal tumour. Updates Surg, 65:71-76, 2013.
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