2018年 業績

論文

• Xiangmin Wang, Bin Pan, Yuko Hashimoto, Hiroshi Ohkawara, Kailin Xu, Lingyu Zeng, Takayuki Ikezoe
  Defibrotide stimulates angiogenesis and protects endothelial cells from calcineurin inhibitor-induced apoptosis via upregulation of AKT/Bcl- xL
  Thrombosis and Haemostasis 118 (1), 161-173, 2018
• Takashi Kaneshiro, Yoshiyuki Matsumoto, Minoru Nodera, Masashi Kamioka, Yoshiyuki Kamiyama, Akiomi Yoshihisa, Hiroshi Ohkawara, Hitoshi Suzuki, Yasuchika Takeishi
  Anatomical predisposing factors of transmural thermal injury after pulmonary vein isolation
  Europace 20 (7), 1122-1128, 2018
• Kaito Harada, Noriko Doki, Jun　Aoki, Jinichi　Mori, Shinichiro Machida, Masayoshi　Masuko, Naoyuki　Uchida, Yuho Najima, Takahiro Fukuda, Heiwa　kanamori, Hiroyasu Ogawa, Shunichi Ota, Kazuei Ogawa, Satoshi Takahashi, Masanobu Kasai, Akiko Maeda, Koji Nagafuji, Toshiro Kawakita, Tatsuo Ichinohe, yoshiko Atsuta
  Outcomes after allogeneic hematopoietic stem cell transplantation in patients with acute myeloid leukemia harboring t(7;11)(p15;p15)
  Haematologica 103 (2), 69-72, 2018
• Keiji Minakawa, Hitoshi Ohto, Hiroyasu Yasuda, Shunichi Saito, Kinuyo Kawabata, Kazuei Ogawa, Kenneth Nollet, Kazuhiko Ikeda
  Efficacy of D- red blood cell transfusion and rituximab therapy in autoimmune hemolytic anemia with anti-D and panreactive autoantibodies arising after hematopoietic stem cell transplant
  Transfusion 58 (7), 1606-1610, 2018
• Satoshi Kimura, Hiroshi Ohkawara, Kazuei Ogawa, Mizuko Tanaka, Takahiro Sano, Kayo Harada-Shirado, Hiroshi Takahashi, Koki Ueda, Akiko Shichishima-Nakamura, Hayato Matsumoto, kazuhiko Ikeda, Junichiro James Kazama, Yuko Hashimoto, Takayuki Ikezoe
  Lenalidomide as a beneficial treatment option for renal impairment caused by light chain deposition disease
  Internal Medicine 15 (24), 3651-3657, 2018
• Yasutaka Ueda, Naoshi Obara, Yuji Yonemura, Hideyoshi Noji, Masayoshi Masuko, Yoshinobu Seki, Katsuya Wada, Takahisa Matsuda, Hirozumi Akiyama, Takayuki Ikezoe, Shigeru Chiba, Yoshinobu Kanda, Tatsuya Kawaguchi, Tsutomu Shichishima, Hideki Nakakuma, Shinichiro Okamoto, Nishimura Jun-ichi, Yuzuru Kanakura, Haruhiko Ninomiya
  Effects of eculizumab treatment on quality of life in patients with paroxysmal nocturnal hemoglobinuria in Japan
  International Journal of Hematology 107 (6), 656-665, 2018
• Kohei Hosokawa, Chiharu Sugimori, Ken Ishiyama, Hiroyuki Takamatsu, Hideyoshi Noji, Tsutomu Shichishima, Naoshi Obara, Shigeru Chiba, Haruhiko Ninomiya, Yukari Shirasugi, Yoshihiko Nakamura, Kiyoshi Ando, Yasutaka Ueda, Yuji Yonemura, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
  Establishment of a flow cytometry assay for detecting paroxysmal nocturnal hemoglobinuria-type cells specific to patients with bone marrow failure
  Annals of Hematology 97 (12), 2289-2297, 2018
• Masayuki Mita, Tsutomu Shichishima, Hideyoshi Noji
  Independent paroxysmal nocturnal hemoglobinuria and myelodysplastic syndrome clones in a patient with complete bone marrow failure
  HemaSphere 2 (5), e142, 2018
• Bin Pan, Jing Yang, Xiangmin Wang, Kailin Xu, Takayuki Ikezoe
  miR-217 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitors by targeting pro-oncogenic anterior gradient 2
  Experimental Hematology 68, 80-88, 2018
• Xiangmin　Wang, Bin Pan, Goichi Honda, Xintao Wang, Yuko Hashimoto, Hiroshi Ohkawara, Kailin Xu, Lingyu Zeng, Takayuki Ikezoe
  Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain
  Haematologica 103 (10), 1730-1740, 2018
• Takashi Kaneshiro, Yoshiyuki Matsumoto, Naoko Hijioka, Minoru Nodera, Shinya Yamada, Masashi Kamioka, Akiomi Yoshihisa, Hiroshi Ohkawara, Hitoshi Suzuki, Yasuchika Takeishi
  Distinct forms of esophageal lesions after radiofrequency and cryoballoon pulmonary vein isolation
  JACC: Clinical Electrophysiology 4 (12), 1642-1643, 2018
• 高橋裕志, 大河原浩, 七島晶子, 深津真彦, 佐野隆浩, 原田佳代, 木村　哲, 東川隆一, 田崎和洋, 橋本優子, 小川一英, 池添隆之
  気管に限局して発症し気管閉塞を来たした節外性NK/T細胞リンパ腫,鼻型
  臨床血液 59 (8), 1012-1015, 2018
• 池添隆之
  造血幹細胞移植後のTMA診療
  臨床血液 59 (10), 2307-2314, 2018
• 松田　信, 深津真彦, 木村　悟, 斎藤由理恵, 神林裕行, 小田島肇
  巨核球との鑑別が困難な巨大多核骨髄腫細胞がみられたBJP-κ型骨髄腫
  臨床血液 59 (6), 667, 2018
• 松田　信, 深津真彦, 木村　悟, 岡本正俊, 斎藤由理恵, 神林裕行, 小田島肇
  組織球の細胞質内に多数の菱形結晶を認めるcrystal storing histiocytosisを合併したIgA-κ型多発性骨髄腫
  臨床血液 59 (8), 989, 2018

学会発表 - 国際学会

• AACR Annual Meeting 2018 (2018.4.14-4.18, Chicago, Illinois, USA)
  Bin Pan, Xiangmin Wang, Kailin Xu, Takayuki Ikezoe
  miR-217 sensitizes chronic myelogenous leukemia cells to tyrosine kinase inhibitors by targeting pro-oncogenic anterior gradient 2
• 第23回　欧州血液学会　EHA 2018 - The 23rd European Hematology Association Congress (2018.6.14-6.17, Stockholm, Sweden)
  Kohei Hosokawa, Ken Ishiyama, Toshiyuki Ikemoto, Chiharu Sugimori, Hideyoshi Noji, Tsutomu Shichishima, Naoshi Obara, Shigeru Chiba , Haruhiko Ninomiya, Yukari Shirasugi, Yoshihiko Nakamura, Kiyoshi Ando, Yasutaka Ueda , Yuji Yonemura, Tatsuya Kawaguchi, Jun-ichi Nishimura, Yuzuru Kanakura, Shinji Nakao
  A comparison of the accuracy in detecting mino PNH clones in patients with bone marrow failure between two high-sensitivity flow cytometry assays: CLSI and OPTIMA
• 64th Annual ISTH SSC meeting (2018.7.18-7.21, Ireland)
  Xiangmin Wang, Xintao Wang, Takakazu Kawase, Goichi Honda, Hiroshi Ohkawara, Takayuki Ikezoe
  Recombinant human soluble thrombomodulin protects vascular endothelial cells from radiation-induced DNA damage
• 60th American Society of Hematology (ASH) Annual Meeting and Exposition
  第60回　米国血液学会 (2018.12.1-12.4, San Diego)
  Kenji Minakawa, Koki Ueda, Akiko Shichishima, Hiroshi Ohkawara, Kazuei Ogawa, Takayuki Ikezoe, Yayoi Shikama, Kenneth Nollet, Kazuhiko Ikeda
  HMGA2 mRNA expression in patients with myelodysplastic/myeloproliferative neoplasms (MDS/MPN)
  Blood 132 (Suppl 1), 4384, 2018
• 60th American Society of Hematology (ASH) Annual Meeting and Exposition
  第60回　米国血液学会 (2018.12.1-12.4, San Diego)
  Miki Furukawa, Wang Xintao, Hiroshi Ohkawara, Masahiko Fukatsu, Lobna Alkebsi, Hideyoshi Noji, Kazuei Ogawa, Takayuki Ikezoe
  A critical role of growth arrest-specific gene 6-Mer axis in the pathogenesis of endothelial damage contributing to thrombotic microangiopathy associated with graft-versus-host disease after allogeneic hematopoietic stem cell transplantation
  Blood 132 (Suppl 1), 4520, 2018

学会発表 - 国内総会 - 一般演題

• 第40回　日本造血細胞移植学会総会 (2018.2.1-2.3, 札幌)
  深津真彦, 七島晶子, 木村　哲, 大河原浩, 池田和彦, 小川一英, 池添隆之
  慢性リンパ性白血病に対する骨髄破壊的前処置を用いた同種造血幹細胞移植 の１例
• 第40回　日本造血細胞移植学会総会 (2018.2.1-2.3, 札幌)
  木村　哲, 池田和彦, 大戸　斉, 池添隆之, 小川一英, 菊田敦, 佐野秀樹, 大 河原浩, 原田佳代, 齋藤俊一, 皆川敬治
  G-CSFの投与法と末梢血幹細胞採取効率
• 第40回　日本血栓止血学術集会 (2018.6.28-6.30, 札幌)
  深津真彦, 助川真純, 七島晶子, 鈴木裕子, 佐野隆浩, 原田佳代, 木村　哲, 大河原浩, 小川一英, 池添隆之
  後天性von Willebrand 病の合併が疑われた急性骨髄性白血病の1 例
• 第40回　日本血栓止血学術集会 (2018.6.28-6.30, 札幌)
  池添隆之, 王　祥民, 王　新涛, 大河原浩, 本田剛一
  TM の血管新生作用と内皮保護作用は5 番目の上皮細胞増殖因子様領域のC ループに局在する
• 第40回　日本血栓止血学術集会 (2018.6.28-6.30, 札幌)
  和田英夫, 内山俊正, 川杉和夫, 窓岩清治, 竹迫直樹, 鈴木　圭, 河野徳明, 関　義信, 池添隆之, 本田剛一, 岡本好司
  DIC ならびにDIC 疑い症例の病態解析
• 第66回　日本心臓病学会学術集会 (2018.9.7, 大阪)
  丹治麻衣子, 小室和子, 高田佳奈, 小松真司, 金内あかね, 金澤晃子,
  深津真彦, 神林裕行, 小田島肇, 高野真澄
  急性骨髄性白血病患者における白血病細胞の心筋浸潤 骨髄移植後再発時の急速な心室壁肥厚と化学療法後の改善を認めた1例
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  Miki Furukawa, Hiroshi Ohkawara, Wang Xiangmin, Kazuei Ogawa, Takayuki Ikezoe
  Gas6-MerTK plays an important role in the pathogenesis of HSCT- associated thrombotic microangiopathy
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  原田佳代, 深津真彦, 佐野隆浩, 木村　哲, 高橋裕志, 七島晶子, 大河原浩, 小川一英, 神林裕行, 齋藤由理恵, 木村　悟, 助川真純, 阿久津和子, 濱崎洋一, 甲斐龍幸, 三田正行, 大田雅嗣, 池添隆之
  未治療低悪性度B細胞リンパ腫に対するR-Benda療法の後方視的検討
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  Keiji Minakawa, Koki　Ueda, Osamu Nakajima, Takayuki Ikezoe, Yasuchika Takeishi, Kazuhiko Ikeda
  Analysis of myeloproliferative neoplasm hematopoiesis with knock-in mice with Calr mutants
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  Aki Yanagi, Naohiro Tsuyama, Yukari Yanai, Yu Abe, Misaki Sugai, Akinobu Ota, Karnan Sivasundaran, Megumi　Sasatani, Kenji Kamiya, Ichiro Hanamura, Takayuki Ikezoe, Masafumi Onodera, Akira Sakai
  Attempt to make abnormal B lymphocytes as myeloma-initiating cells from B-iPSCs
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  Hideyoshi Noji, Yasutaka Ueda, Naoshi Obara, Yoshinobu Kanda, Shinichiro Okamoto, Kensuke Usuki, Takahisa Matsuda, Hirozumi Akiyama, Masanori Takahashi, Yuji Yonemura, Tatsuya kawaguchi, Jun- Ichi Nishimura, Takayuki Ikezoe, Shigeru Chiba, Yuzuru Kanakura, Haruhiko Ninomiya
  Interim analysis of post marketing surketing surveillance on PNH： long-term interverntion with eculizumab
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  木村　哲, 佐野隆浩, 深津真彦, 原田佳代, 高橋裕志, 七島晶子, 大河原浩, 野地秀義, 小川一英, 池添隆之
  当院における中枢神経系原発DLBCLの治療成績
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  Hirotake Mori, Yoshihiro Nozawa, Ken-ichi Nakamura, Takayuki Ikezoe, Masayuki Mita
  Differential diagnosis and treatment in a patient with testicular plasmablastic lymphoma
• 第80回　日本血液学会学術集会 (2018.10.12-10.14, 大阪)
  高橋裕志, 野地秀義, 木村　哲, 大河原浩, 七島晶子, 原田佳代, 佐野隆浩, 深津真彦, 池添隆之
  単施設における眼内悪性リンパ腫症例の後方視的解析