Organization
Research Facility Attached to the School of Medicine Department of Cell Science Assistant Professor
Title
Assistant Professor
MUNAKATA Yasuhisa
Research History
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Fukushima Medical University School of Medicine Institute of Biomedical Sciences Assistant Professor
2024.10 - Now
Papers
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Newly Evolved Endogenous Retroviruses Prime the Ovarian Reserve for Activation.
Munakata Y, Hu M, Dani R, Inoue N, Schultz R, Namekawa S
Research square 2025.12
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Newly Evolved Endogenous Retroviruses Prime the Ovarian Reserve for Activation
Yasuhisa Munakata, Mengwen Hu, Raissa G Dani, Naokazu Inoue, Richard M Schultz, Satoshi H Namekawa
2025.11
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The SMARCA5–DMRT1 Pioneer Complex Establishes Epigenetic Priming to Direct Male Germline Development
Yuka Kitamura, Yasuhisa Munakata, Hironori Abe, Mengwen Hu, Satoyo Oya, Shanmathi Murugesan, Mahnoor Rizwan, Shawna P. Katz, David J. Picketts, Richard M. Schultz, Satoshi H. Namekawa
2025.7
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An Epigenomic Roadmap Primes Non-Growing Oocytes for Maturation and Early Embryogenesis
Mengwen Hu, Yasuhisa Munakata, Yu-Han Yeh, Han Wang, Neil Hunter, Richard M. Schultz, Satoshi H. Namekawa
2025.7
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CTCF-mediated 3D chromatin sets up the gene expression program in the male germline
Yuka Kitamura, Kazuki Takahashi, So Maezawa, Yasuhisa Munakata, Akihiko Sakashita, Shawna P. Katz, Noam Kaplan, Satoshi H. Namekawa
Nature Structural & Molecular Biology 32 ( 7 ) 1227 - 1240 2025.7（ ISSN:1545-9993 ）
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Chromatin remodeler CHD4 establishes chromatin states required for ovarian reserve formation, maintenance and male germ cell survival
Yasuhisa Munakata, Mengwen Hu, Yuka Kitamura, Raissa G Dani, Adam L Bynder, Amelia S Fritz, Richard M Schultz, Satoshi H Namekawa
Nucleic Acids Research 2025.1
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ATF7IP2/MCAF2 directs H3K9 methylation and meiotic gene regulation in the male germline
Kris G. Alavattam, Jasmine M. Esparza, Mengwen Hu, Ryuki Shimada, Anna R. Kohrs, Hironori Abe, Yasuhisa Munakata, Kai Otsuka, Saori Yoshimura, Yuka Kitamura, Yu-Han Yeh, Yueh-Chiang Hu, Jihye Kim, Paul R. Andreassen, Kei-ichiro Ishiguro, Satoshi H. Namekawa
Genes & Development 2024.2
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Active DNA damage response signaling initiates and maintains meiotic sex chromosome inactivation.
Hironori Abe, Yu-Han Yeh, Yasuhisa Munakata, Kei-Ichiro Ishiguro, Paul R Andreassen, Satoshi H Namekawa
Nature communications 13 ( 1 ) 7212 - 7212 2022.11
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PRC1-mediated epigenetic programming is required to generate the ovarian reserve.
Mengwen Hu, Yu-Han Yeh, Yasuhisa Munakata, Hironori Abe, Akihiko Sakashita, So Maezawa, Miguel Vidal, Haruhiko Koseki, Neil Hunter, Richard M Schultz, Satoshi H Namekawa
Nature communications 13 ( 1 ) 4510 - 4510 2022.8
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Prediction of major microRNAs in follicular fluid regulating porcine oocyte development.
Yuki Inoue, Yasuhisa Munakata, Akihisa Shinozawa, Ryoka Kawahara-Miki, Koumei Shirasuna, Hisataka Iwata
Journal of assisted reproduction and genetics 37 ( 10 ) 2569 - 2579 2020.10
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Comparison of gene expression and mitochondria number between bovine blastocysts obtained in vitro and in vivo.
Tatsuo Noguchi, Takuro Aizawa, Yasuhisa Munakata, Hisataka Iwata
The Journal of reproduction and development 66 ( 1 ) 35 - 39 2020.2
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Xanthan gum and Locust bean gum gel supports in vitro development of porcine oocytes derived from early antral follicles.
Yasuhisa Munakata, Ayaka Sugimoto, Koumei Shirasuna, Takehito Kuwayama, Hisataka Iwata
The Journal of reproduction and development 65 ( 6 ) 551 - 554 2019.12
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Mitochondrial cell-free DNA secreted from porcine granulosa cells.
Kazuki Kansaku, Yasuhisa Munakata, Koumei Shirasuna, Takehito Kuwayama, Hisataka Iwata
Zygote (Cambridge, England) 27 ( 5 ) 272 - 278 2019.10
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Modification of the medium volume and gel substrate under in vitro culture conditions improves growth of porcine oocytes derived from early antral follicles.
Hidenori Shibahara, Yasuhisa Munakata, Ai Ishiguro, Koumei Shirasuna, Takehito Kuwayama, Hisataka Iwata
The Journal of reproduction and development 65 ( 4 ) 375 - 379 2019.8
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Cell-free DNA in medium is associated with the maturation ability of in vitro cultured oocytes.
Yasuhisa Munakata, Koumei Shirasuna, Takehito Kuwayama, Hisataka Iwata
The Journal of reproduction and development 65 ( 2 ) 171 - 175 2019.4
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Addition of granulosa cells collected from differential follicle stages supports development of oocytes derived from porcine early antral follicles.
Ai Ishiguro, Yasuhisa Munakata, Koumei Shirasuna, Takehito Kuwayama, Hisataka Iwata
Reproductive medicine and biology 18 ( 1 ) 65 - 71 2019.1
Awards
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優秀発表賞
2023.9
Research Projects
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Extracellular nucleic acid to regulate the follicular development
Grant number：18J12261 2018.4 - 2020.3
Grant-in-Aid for JSPS Fellows
Grant amount：\2100000 （ Direct Cost: \2100000 ）