Papers - NAKAJIMA Shotaro
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The tumor cell-intrinsic cGAS-STING pathway is associated with the high density of CD8+ T cells after chemotherapy in esophageal squamous cell carcinoma.
Akira Matsuishi, Shotaro Nakajima, Akinao Kaneta, Katsuharu Saito, Satoshi Fukai, Mei Sakuma, Hideaki Tsumuraya, Hirokazu Okayama, Motonobu Saito, Kosaku Mimura, Azuma Nirei, Tomohiro Kikuchi, Hiroyuki Hanayama, Zenichiro Saze, Wataru Sakamoto, Tomoyuki Momma, Koji Kono
Esophagus : official journal of the Japan Esophageal Society 21 ( 2 ) 165 - 175 2024.2（ ISSN:1612-9059 ）
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Down-regulation of stimulator of interferon genes (STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.
Satoshi Fukai, Shotaro Nakajima, Motonobu Saito, Katsuharu Saito, Koji Kase, Hiroshi Nakano, Takahiro Sato, Mei Sakuma, Akinao Kaneta, Hirokazu Okayama, Kosaku Mimura, Wataru Sakamoto, Zenichiro Saze, Tomoyuki Momma, Koji Kono
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 6 ) 878 - 890 2023.8（ ISSN:1436-3291 ）
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High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8(+) T cells in dMMR/MSI-H gastric cancer.
Kanoda R, Nakajima S, Fukai S, Saito M, Saito K, Suzuki H, Kikuchi T, Nirei A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K
Scientific reports 14 ( 1 ) 20859 2024.9
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胃癌におけるHER2シグナルを介した腫瘍微小環境の制御 HER2過剰発現の腫瘍内不均一性を呈する胃癌症例からの検討
中嶋正太郎, 深井 智司, 金田 晃尚, 圓谷 秀哲, 松石 彬, 岡山 洋和, 齋藤 元伸, 三村 耕作, 坂本 渉, 佐瀬 善一郎, 門馬 智之, 河野 浩二
癌と化学療法 51 ( 9 ) 903 - 905 2024.9
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The impact of CLDN18.2 expression on effector cells mediating antibody-dependent cellular cytotoxicity in gastric cancer.
Matsuishi A, Nakajima S, Saito M, Saito K, Fukai S, Tsumuraya H, Kanoda R, Kikuchi T, Nirei A, Kaneta A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K
Scientific reports 14 ( 1 ) 17916 2024.8
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Tumor Infiltrating Effector Regulatory T Cells Express VEGF Receptor 2 in Patients With Colorectal Cancer.
Tsumuraya H, Mimura K, Nakajima S, Hanayama H, Matsuishi A, Okayama H, Fukai S, Ito M, Ashizawa M, Chida S, Onozawa H, Sakamoto W, Saito M, Saze Z, Momma T, Kono K
Anticancer research 44 ( 7 ) 2933 - 2941 2024.7
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α7 nicotinic acetylcholine receptor agonist attenuates allergen-induced immediate nasal response in murine model of allergic rhinitis.
Shuhei Yamashita, Kento Miura, Anna Matsuura, Norimasa Yamasaki, Naoto Uda, Sawako Ogata, Naohisa Hosomi, Shotaro Nakajima, Noriko Kitamura, Minoru Gotoh, Akio Mori, Osamu Kaminuma
The Journal of veterinary medical science 86 ( 7 ) 824 - 827 2024.6（ ISSN:0916-7250 ）
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食道癌の生物学 食道癌の腫瘍免疫微小環境
中嶋正太郎, 河野浩二
日本臨牀 食道癌2024ー基礎・臨床の最新動向ー 82 ( 3 ) 90 - 95 2024.5
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TIM-3 expression on dendritic cells in colorectal cancer
Mei Sakuma, Masanori Katagata, Hirokazu Okayama, Shotaro Nakajima, Katsuharu Saito, Takahiro Sato, Satoshi Fukai, Hideaki Tsumuraya, Hisashi, Onozawa, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Koji Kono
Cancers 16 ( 10 ) 1888 - 1888 2024.5（ ISSN:2072-6694 ）
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TGFβ-Responsive Stromal Activation Occurs Early in Serrated Colorectal Carcinogenesis.
Hideaki Tsumuraya, Hirokazu Okayama, Masanori Katagata, Akira Matsuishi, Satoshi Fukai, Misato Ito, Wataru Sakamoto, Motonobu Saito, Tomoyuki Momma, Shotaro Nakajima, Kosaku Mimura, Koji Kono
International journal of molecular sciences 25 ( 9 ) 4626 - 4626 2024.4
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Biomarker-oriented chemo-immunotherapy for advanced gastric cancer.
Koji Kono, Shotaro Nakajima, Kosaku Mimura
International journal of clinical oncology 29 ( 7 ) 865 - 872 2024.4（ ISSN:1341-9625 ）
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Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer.
Kosaku Mimura, Takashi Ogata, Phuong H D Nguyen, Souvick Roy, Hassen Kared, Yate-Ching Yuan, Michael Fehlings, Yuya Yoshimoto, Daisaku Yoshida, Shotaro Nakajima, Hisashi Sato, Nozomu Machida, Takanobu Yamada, Yohei Watanabe, Tomoaki Tamaki, Hirohito Fujikawa, Yasuhiro Inokuchi, Suguru Hayase, Hiroyuki Hanayama, Zenichiro Saze, Hiroyuki Katoh, Fumiaki Takahashi, Takashi Oshima, Ajay Goel, Alessandra Nardin, Yoshiyuki Suzuki, Koji Kono
Journal for immunotherapy of cancer 12 ( 1 ) e008385 2024.1
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TIM-3 expression and M2 polarization of macrophages in the TGFβ-activated tumor microenvironment in colorectal cancer
Masanori Katagata, Hirokazu Okayama, Shotaro Nakajima, Katsuharu Saito, Takahiro Sato, Mei Sakuma, Satoshi Fukai, Eisei Endo, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Koji Kono
Cancers 20 ( 15 ) 4943 2023.10（ ISSN:2072-6694 ）
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放射線治療による腫瘍細胞内cGAS-STING経路を介した食道扁平上皮癌微小環境の変化
中嶋正太郎, 三村耕作, 金田晃尚, 片方雅紀, 岡山洋和, 齋藤元伸, 佐瀬善一郎, 花山寛之, 多田武志, 門馬智之, 河野浩二
癌と化学療法 50 ( 10 ) 1099 - 1101 2023.10
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[Remodeling of the Tumor Microenvironment by Radiotherapy through the cGAS-STING Pathway in Esophageal Squamous Cell Carcinoma].
Nakajima S, Mimura K, Kaneta A, Katagata M, Okayama H, Saito M, Saze Z, Hanayama H, Tada T, Momma T, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 50 ( 10 ) 1099 - 1101 2023.10（ ISSN:0385-0684 ）
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Remodeling of the tumor microenvironment by radiotherapy through the cGAS-STING pathway in esophageal squamous cell carcinoma
Shotaro Nakajima, Kosaku Mimura, Akinao Kaneta, Masanori Katagata, Hirokazu Okayama, Motonobu Saito, Zenichiro Saze, Hiroyuki Hanayama, Takeshi Tada, Tomoyuki Momma, Koji Kono
Gan to kagaku ryoho. Cancer & chemotherapy 50 ( 10 ) 1099 - 1101 2023.10（ ISSN:0385-0684 ）
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[The Potential of a Novel Therapeutic Strategy for Colorectal Cancer Targeting the cGAS-STING Pathway].
Shotaro Nakajima, Akinao Kaneta, Koji Kono
Gan to kagaku ryoho. Cancer & chemotherapy 50 ( 9 ) 950 - 954 2023.9（ ISSN:0385-0684 ）
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[The Potential of a Novel Therapeutic Strategy for Colorectal Cancer Targeting the cGAS-STING Pathway].
Nakajima S, Kaneta A, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 50 ( 9 ) 950 - 954 2023.9（ ISSN:0385-0684 ）
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Phase I/II clinical trial of nivolumab in combination with oligo-fractionated irradiation for unresectable advanced or recurrent gastric cancer.
Kosaku Mimura, Takashi Ogata, Yuya Yoshimoto, Daisaku Yoshida, Shotaro Nakajima, Hisashi Sato, Nozomu Machida, Takanobu Yamada, Yohei Watanabe, Tomoaki Tamaki, Hirohito Fujikawa, Yasuhiro Inokuchi, Suguru Hayase, Hiroyuki Hanayama, Zenichiro Saze, Hiroyuki Katoh, Fumiaki Takahashi, Takashi Oshima, Yoshiyuki Suzuki, Koji Kono
Communications medicine 3 ( 1 ) 111 - 111 2023.8
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Down-regulation of stimulator of interferon genes (STING) expression and CD8(+) T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.
Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K
Gastric cancer 26 ( 6 ) 878 - 890 2023.8
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A Potential Biomarker of Dynamic Change in Peripheral CD45RA(-)CD27(+)CD127(+) Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma.
Sakuma M, Mimura K, Nakajima S, Kaneta A, Kikuchi T, Nirei A, Tada T, Hanayama H, Okayama H, Sakamoto W, Saito M, Momma T, Saze Z, Kono K
Cancers 15 ( 14 ) 3641 2023.7（ ISSN:2072-6694 ）
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The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8(+) T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer.
Nakajima S, Kaneta A, Okayama H, Saito K, Kikuchi T, Endo E, Matsumoto T, Fukai S, Sakuma M, Sato T, Mimura K, Saito M, Saze Z, Sakamoto W, Onozawa H, Momma T, Kono K
Cancers 15 ( 10 ) 2826 2023.5（ ISSN:2072-6694 ）
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Radiation-Induced Remodeling of the Tumor Microenvironment Through Tumor Cell-Intrinsic Expression of cGAS-STING in Esophageal Squamous Cell Carcinoma.
Nakajima S, Mimura K, Kaneta A, Saito K, Katagata M, Okayama H, Saito M, Saze Z, Watanabe Y, Hanayama H, Tada T, Sakamoto W, Momma T, Ohira H, Kono K
International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2023.3（ ISSN:0360-3016 ）
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M2 tumor-associated macrophages resist to oxidative stress through heme oxygenase-1 in the colorectal cancer tumor microenvironment.
Ito M, Mimura K, Nakajima S, Okayama H, Saito K, Nakajima T, Kikuchi T, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Kono K
Cancer immunology, immunotherapy : CII 72 ( 7 ) 2233 - 2244 2023.3（ ISSN:0340-7004 ）
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ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 3 ) 379 - 392 2023.2（ ISSN:1436-3291 ）
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用語解説
中嶋正太郎
分子細胞免疫学 原著第10版 アバス-リックマン-ピレ 535 - 564 2023.1
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Phase I/II clinical trial of nivolumab in combination with oligo-fractionated irradiation for unresectable advanced or recurrent gastric cancer.
Mimura K, Ogata T, Yoshimoto Y, Yoshida D, Nakajima S, Sato H, Machida N, Yamada T, Watanabe Y, Tamaki T, Fujikawa H, Inokuchi Y, Hayase S, Hanayama H, Saze Z, Katoh H, Takahashi F, Oshima T, Suzuki Y, Kono K
Cancer medicine 3 ( 1 ) 111 2023
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TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer.
Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, Fukai S, Endo E, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
Cancers 15 ( 20 ) 4943 2023
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cGAS-STING経路を標的とした大腸癌の新規治療戦力の可能性
中嶋正太郎, 金田晃尚, 河野浩二
癌と化学療法 50 ( 9 ) 950 - 954 2023
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Radiation-induced remodeling of the tumor-microenvironment through tumor cell-intrinsic expression of cGAS-STING in esophageal squamous cell carcinoma.
Shotaro Nakajima, Kosaku Mimura, Akinao Kaneta, Katsuharu Saito, Masanori Katagata, Hirokazu Okayama, Motonobu Saito, Zenichiro Saze, Yohei Watanabe, Hiroyuki Hanayama, Takeshi Tada, Wataru Sakamoto, Tomoyuki Momma, Hiromasa Ohira, Koji Kono
International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2022.11（ ISSN:0360-3016 ）
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[Expression of the cGAS-STING Pathway in dMMR/MSI-H in Colorectal Cancer].
Akinao Kaneta, Shotaro Nakajima, Kosaku Mimura, Koji Kono
Gan to kagaku ryoho. Cancer & chemotherapy 49 ( 10 ) 1130 - 1132 2022.10（ ISSN:0385-0684 ）
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dMMR/MSI-H大腸癌におけるcGAS-STING経路の発現
金田晃尚，中嶋正太郎，三村耕作，河野浩二
癌と化学療法 49 ( 10 ) 1130 - 1132 2022.10
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Immune escape mechanism behind resistance to anti-PD-1 therapy in gastrointestinal tract metastasis in malignant melanoma patients with multiple metastases
Ito M, Mimura K, Nakajima S, Saito K, Min AKT, Okayama H, Saito M, Momma T, Saze Z, Ohtsuka M, Yamamoto T, Kono K.
Cancer Immunol Immunother. 71 ( 9 ) 2293 - 2300 2022.9
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Akinao Kaneta, Shotaro Nakajima, Hirokazu Okayama, Takuro Matsumoto, Katsuharu Saito, Tomohiro Kikuchi, Eisei Endo, Misato Ito, Kosaku Mimura, Yasuyuki Kanke, Motonobu Saito, Zenichiro Saze, Shotaro Fujita, Wataru Sakamoto, Hisashi Onozawa, Tomoyuki Momma, Shinji Ohki, Koji Kono
Cancer immunology, immunotherapy : CII 71 ( 11 ) 2765 - 2776 2022.4（ ISSN:0340-7004 ）
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Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K
British journal of cancer 126 ( 6 ) 917 - 926 2022.4（ ISSN:0007-0920 ）
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SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer.
Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K
British journal of cancer 126 ( 6 ) 917 - 926 2022.4
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Misato Ito, Kosaku Mimura, Shotaro Nakajima, Katsuharu Saito, Aung Kyi Thar Min, Hirokazu Okayama, Motonobu Saito, Tomoyuki Momma, Zenichiro Saze, Mikio Ohtsuka, Toshiyuki Yamamoto, Koji Kono
Cancer Immunology, Immunotherapy 71 ( 9 ) 2293 - 2300 2022.1（ ISSN:0340-7004 ）
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SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer
Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K
Br J Cancer 2021.12
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Matsumoto T, Okayama H, Nakano H, Ito M, Nakajima S, Saito M, Saze Z, Momma T, Mimura K, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 10 ) 1275 - 1277 2021.10（ ISSN:03850684 ）
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ミスマッチ修復機構欠損大腸癌における糖鎖抗原を標的とした免疫療法の可能性
松本拓朗, 岡山洋和, 仲野宏, 伊藤美郷, 中嶋正太郎, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 河野浩二
癌と化学療法 48 ( 10 ) 1275 - 1277 2021.10（ ISSN:0385-0684 ）
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Prajwal Neupane, Kosaku Mimura, Shotaro Nakajima, Hirokazu Okayama, Misato Ito, Aung Kyi Thar Min, Katsuharu Saito, Hisashi Onozawa, Shotaro Fujita, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Koji Kono
Anticancer research 41 ( 10 ) 4895 - 4905 2021.10（ ISSN:0250-7005 ）
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Shotaro Nakajima, Kosaku Mimura, Takuro Matsumoto, Aung Kyi Thar Min, Misato Ito, Hiroshi Nakano, Prajwal Neupane, Yasuyuki Kanke, Hirokazu Okayama, Motonobu Saito, Tomoyuki Momma, Yohei Watanabe, Hiroyuki Hanayama, Suguru Hayase, Zenichiro Saze, Koji Kono
Scientific reports 11 ( 1 ) 16891 - 16891 2021.8
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S H Petersen, L F Kua, S Nakajima, W P Yong, K Kono
Scientific reports 11 ( 1 ) 12264 - 12264 2021.6
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Naoto Yamauchi, Yasuyuki Kanke, Katsuharu Saito, Hirokazu Okayama, Shoki Yamada, Shotaro Nakajima, Eisei Endo, Koji Kase, Leo Yamada, Hiroshi Nakano, Takuro Matsumoto, Hiroyuki Hanayama, Yohei Watanabe, Suguru Hayase, Motonobu Saito, Zenichiro Saze, Kosaku Mimura, Tomoyuki Momma, Shinji Oki, Yuko Hashimoto, Koji Kono
Oncology letters 21 ( 6 ) 445 - 445 2021.6（ ISSN:1792-1074 ）
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Shotaro Nakajima, Kosaku Mimura, Katsuharu Saito, Aung Kyi Thar Min, Eisei Endo, Leo Yamada, Koji Kase, Naoto Yamauchi, Takuro Matsumoto, Hiroshi Nakano, Yasuyuki Kanke, Hirokazu Okayama, Motonobu Saito, Prajwal Neupane, Zenichiro Saze, Yohei Watanabe, Hiroyuki Hanayama, Suguru Hayase, Akinao Kaneta, Tomoyuki Momma, Shinji Ohki, Hiromasa Ohira, Koji Kono
Molecular cancer research : MCR 19 ( 6 ) 1085 - 1095 2021.6（ ISSN:1541-7786 ）
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ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation.
Koji Kase, Motonobu Saito, Shotaro Nakajima, Daisuke Takayanagi, Katsuharu Saito, Leo Yamada, Mai Ashizawa, Hiroshi Nakano, Hiroyuki Hanayama, Hisashi Onozawa, Hirokazu Okayama, Hisahito Endo, Shotaro Fujita, Wataru Sakamoto, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Shinji Ohki, Kouya Shiraishi, Takashi Kohno, Koji Kono
Carcinogenesis 42 ( 1 ) 21 - 30 2021.2（ ISSN:0143-3334 ）
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Aung Kyi Thar Min, Kosaku Mimura, Shotaro Nakajima, Hirokazu Okayama, Katsuharu Saito, Wataru Sakamoto, Shotaro Fujita, Hisahito Endo, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Shinji Ohki, Koji Kono
Cancer immunology, immunotherapy : CII 70 ( 2 ) 289 - 298 2021.2（ ISSN:0340-7004 ）
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Hiroshi Nakano, Motonobu Saito, Shotaro Nakajima, Katsuharu Saito, Yuko Nakayama, Koji Kase, Leo Yamada, Yasuyuki Kanke, Hiroyuki Hanayama, Hisashi Onozawa, Hirokazu Okayama, Shotaro Fujita, Wataru Sakamoto, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Shinji Ohki, Akiteru Goto, Koji Kono
Scientific reports 11 ( 1 ) 1982 - 1982 2021.1
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Leo Yamada, Motonobu Saito, Aung Kyi Thar Min, Katsuharu Saito, Mai Ashizawa, Koji Kase, Shotaro Nakajima, Hisashi Onozawa, Hirokazu Okayama, Hisahito Endo, Shotaro Fujita, Wataru Sakamoto, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Shinji Ohki, Koji Kono
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 1 ) 60 - 71 2021.1（ ISSN:1436-3291 ）
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Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer.
Yamada L, Saito M, Thar Min AK, Saito K, Ashizawa M, Kase K, Nakajima S, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Kono K
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 1 ) 60 - 71 2021.1（ ISSN:1436-3291 ）
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Activation of the reward system ameliorates passive cutaneous anaphylactic reaction in mice.
Shotaro Nakajima, Satoshi Manita, Guannan Yu, Kayoko Ishimaru, Koji Kono, Kazuo Kitamura, Atsuhito Nakao
Allergy 75 ( 12 ) 3275 - 3279 2020.12（ ISSN:0105-4538 ）
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Tn Antigen Expression Defines an Immune Cold Subset of Mismatch-Repair Deficient Colorectal Cancer.
Takuro Matsumoto, Hirokazu Okayama, Shotaro Nakajima, Katsuharu Saito, Hiroshi Nakano, Eisei Endo, Koji Kase, Misato Ito, Naoto Yamauchi, Leo Yamada, Yasuyuki Kanke, Hisashi Onozawa, Shotaro Fujita, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Koji Kono
International journal of molecular sciences 21 ( 23 ) 9081 - 9081 2020.11（ ISSN:16616596 ）
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A TGFβ-dependent stromal subset underlies immune checkpoint inhibitor efficacy in DNA mismatch repair-deficient/microsatellite instability-high colorectal cancer.
Eisei Endo, Hirokazu Okayama, Katsuharu Saito, Shotaro Nakajima, Leo Yamada, Daisuke Ujiie, Koji Kase, Shotaro Fujita, Hisahito Endo, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Shinji Ohki, Kosaku Mimura, Koji Kono
Molecular cancer research : MCR 18 ( 9 ) 1402 - 1413 2020.9（ ISSN:1541-7786 ）
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Current status of immune checkpoint inhibitors for gastric cancer.
Koji Kono, Shotaro Nakajima, Kosaku Mimura
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 4 ) 565 - 578 2020.7（ ISSN:1436-3291 ）
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Current status of immune checkpoint inhibitors for gastric cancer.
Kono K, Nakajima S, Mimura K.
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 4 ) 565 - 578 2020.7（ ISSN:1436-3291 ）
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cutting-edge medicineがん診療の副作用マネジメント 複合がん免疫療法の発展を目指して
中嶋 正太郎, 河野 浩二
Precision Medicine 3 ( 4 ) 299 - 302 2020.4（ ISSN:2434-3625 ）
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cutting-edge medicine –The development of combination cancer immunotherapy–
Shotaro Nakajima, Koji Kono
Precision Medicine ( 4 ) 1 - 4 2020.3
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Changes in the mental health status of adolescents following the Fukushima Daiichi nuclear accident and related factors: Fukushima Health Management Survey.
Hayashi F, Sanpei M, Ohira T, Nakano H, Okazaki K, Yasumura S, Nakajima S, Yabe H, Suzuki Y, Kamiya K, Fukushima Health Management Survey Group
Journal of affective disorders 260 432 - 439 2020.1（ ISSN:0165-0327 ）
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第10 章 腫瘍免疫学と移植免疫学 がん細胞と正常非自己細胞に対する免疫応答
中尾篤人，井上修，氏家大輔，内田萌菜，柏木麻里子，香山尚子，河合利尚，木村元子，河野浩二，佐藤卓哉，竹田潔，中嶋正太郎，中野信浩，中山俊憲，中山勝文，廣瀬晃一，穂積勝人，村上正晃，村上悠二，八木良二，松嶋綱治，山田幸宏
基礎免疫学 原著第6 版 免疫系の機能とその異常 185 - 205 2020
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Ishimaru K, Nakajima S, Yu G, Nakamura Y, Nakao A
International journal of molecular sciences 20 ( 24 ) 2019.12（ ISSN:16616596 ）
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Resveratrol inhibits IL-33-mediated mast cell activation by targeting the MK2/3-PI3K/Akt axis.
Nakajima S, Ishimaru K, Kobayashi A, Yu G, Nakamura Y, Oh-Oka K, Suzuki-Inoue K, Kono K, Nakao A
Scientific reports 9 ( 1 ) 18423 2019.12
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The frequency of Th17 cells in the small intestine exhibits a day-night variation dependent on circadian clock activity.
Ha Pham Thu Le, Yuki Nakamura, Kyoko Oh-Oka, Kayoko Ishimaru, Shotaro Nakajima, Atsuhito Nakao
Biochemical and biophysical research communications 490 ( 2 ) 290 - 295 2017.8
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Induction of Colonic Regulatory T Cells by Mesalamine by Activating the Aryl Hydrocarbon Receptor.
Kyoko Oh-Oka, Yuko Kojima, Koichiro Uchida, Kimiko Yoda, Kayoko Ishimaru, Shotaro Nakajima, Jun Hemmi, Hiroshi Kano, Yoshiaki Fujii-Kuriyama, Ryohei Katoh, Hiroyuki Ito, Atsuhito Nakao
Cellular and molecular gastroenterology and hepatology 4 ( 1 ) 135 - 151 2017.7
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Mimura K, Kua LF, Shimasaki N, Shiraishi K, Nakajima S, Siang LK, Shabbir A, So J, Yong WP, Kono K
Cancer immunology, immunotherapy : CII 66 ( 5 ) 605 - 613 2017.5（ ISSN:0340-7004 ）
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Selective deletion of adipocytes, but not preadipocytes, by TNF-α through C/EBP- and PPARγ-mediated suppression of NF-κB.
Minori Tamai, Tsuyoshi Shimada, Nobuhiko Hiramatsu, Kunihiro Hayakawa, Maro Okamura, Yasuhiro Tagawa, Shuhei Takahashi, Shotaro Nakajima, Jian Yao, Masanori Kitamura
Laboratory investigation; a journal of technical methods and pathology 97 ( 2 ) 228 - 228 2017.2
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Shiraishi K, Mimura K, Kua LF, Koh V, Siang LK, Nakajima S, Fujii H, Shabbir A, Yong WP, So J, Takenoshita S, Kono K
Journal of gastroenterology 51 ( 12 ) 1101 - 1111 2016.12（ ISSN:0944-1174 ）
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Nakajima S, Koh V, Kua LF, So J, Davide L, Lim KS, Petersen SH, Yong WP, Shabbir A, Kono K
Journal of immunology (Baltimore, Md. : 1950) 197 ( 9 ) 3735 - 3745 2016.11（ ISSN:0022-1767 ）
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eIF2α-independent inhibition of TNF-α-Triggered NF-κB activation by salubrinal
Nakajima S., Chi Y., Gao K., Kono K., Yao J.
Biological and Pharmaceutical Bulletin 38 ( 9 ) 1368 - 1374 2015.9（ ISSN:09186158 ）
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Purinergic control of AMPK activation by ATP released through connexin 43 hemichannels - pivotal roles in hemichannel-mediated cell injury.
Yuan Chi, Kun Gao, Kai Li, Shotaro Nakajima, Satoru Kira, Masayuki Takeda, Jian Yao
Journal of cell science 127 ( Pt 7 ) 1487 - 99 2014.4
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Acidic stress-ER stress axis for blunted activation of NF-kappa B in mesothelial cells exposed to peritoneal dialysis fluid (vol 27, pg 4053, 2012)
Hisashi Johno, Ryouji Ogata, Shotaro Nakajima, Nobuhiko Hiramatsu, Tetsuro Kobayashi, Hideaki Hara, Masanori Kitamura
NEPHROLOGY DIALYSIS TRANSPLANTATION 29 ( 2 ) 470 - 470 2014.2（ ISSN:0931-0509 ）
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Bidirectional regulation of NF-κB by reactive oxygen species: a role of unfolded protein response.
Shotaro Nakajima, Masanori Kitamura
Free radical biology & medicine 65 162 - 174 2013.12（ ISSN:0891-5849 ）
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Selective, potent blockade of the IRE1 and ATF6 pathways by 4-phenylbutyric acid analogues.
Hui Zhang, Shotaro Nakajima, Hironori Kato, Liubao Gu, Tatsuya Yoshitomi, Kaoru Nagai, Hideyuki Shinmori, Susumu Kokubo, Masanori Kitamura
British journal of pharmacology 170 ( 4 ) 822 - 34 2013.10
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Intervention in genotoxic stress-induced senescence by cordycepin through activation of eIF2α and suppression of Sp1.
Liubao Gu, Hisashi Johno, Shotaro Nakajima, Tatsuya Yoshitomi, Shuhei Takahashi, Masanori Kitamura
Toxicological sciences : an official journal of the Society of Toxicology 134 ( 2 ) 345 - 54 2013.8
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Pleiotropic Potential of Dehydroxymethylepoxyquinomicin for NF-kappa B Suppression via Reactive Oxygen Species and Unfolded Protein Response
Shotaro Nakajima, Hironori Kato, Liubao Gu, Shuhei Takahashi, Hisashi Johno, Kazuo Umezawa, Masanori Kitamura
JOURNAL OF IMMUNOLOGY 190 ( 12 ) 6559 - 6569 2013.6（ ISSN:0022-1767 ）
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Blockade of Smad signaling by 3'-deoxyadenosine: a mechanism for its anti-fibrotic potential.
Liubao Gu, Hisashi Johno, Shotaro Nakajima, Hironori Kato, Shuhei Takahashi, Ryohei Katoh, Masanori Kitamura
Laboratory investigation; a journal of technical methods and pathology 93 ( 4 ) 450 - 61 2013.4