Updated on 2023/06/28

写真a

 
OHKAWARA Hiroshi
 
Organization
School of Medicine (Clinical Medicine) Department of Hematology Postdoctoral Researcher
Title
Postdoctoral Researcher

Degree

  • 医学博士 ( 2004.3   福島県立医科大学 )

Research Interests

  • 血管内皮細胞障害、動脈硬化、凝固異常、造血器腫瘍、造血幹細胞移植

Research Areas

  • Life Science / Hematology and medical oncology  / Hematology

  • Life Science / Cardiology  / 動脈硬化

Research History

  • Fukushima Medical University   School of Medicine (Clinical Medicine) Department of Hematology   Postdoctoral Researcher

    2022.4 - Now

  • Fukushima Medical University   School of Medicine (Clinical Medicine) Department of Hematology   Associate Professor

    2017.5 - 2022.3

  • Fukushima Medical University   School of Medicine (Clinical Medicine) Department of Hematology   Associate Professor

    2017.2 - 2017.4

Professional Memberships

  • 日本循環器学会

  • 日本内科学会

  • 日本消化器内視鏡学会

  • 日本血液学会

  • 日本造血細胞移植学会

Papers

  • Dasatinib induces endothelial-to-mesenchymal transition in human vascular-endothelial cells: counteracted by cotreatment with bosutinib.

    Alkebsi L, Wang X, Ohkawara H, Fukatsu M, Mori H, Ikezoe T

    International journal of hematology   113 ( 3 )   441 - 455   2021.3( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s12185-020-03034-1

    PubMed

  • Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia.

    Harada-Shirado K, Wang X, Mori H, Fukatsu M, Takahashi H, Shichishima-Nakamura A, Kimura S, Ohkawara H, Yamada S, Ito T, Ikezoe T

    International journal of hematology   111 ( 3 )   378 - 387   2020.3( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s12185-019-02798-5

    PubMed

  • Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia(和訳中)

    Harada-Shirado Kayo, Wang Xintao, Mori Hirotaka, Fukatsu Masahiko, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Kimura Satoshi, Ohkawara Hiroshi, Yamada Shingo, Ito Takashi, Ikezoe Takayuki

    International Journal of Hematology   111 ( 3 )   378 - 387   2020.3( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia.

    Harada-Shirado Kayo, Wang Xintao, Mori Hirotaka, Fukatsu Masahiko, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Kimura Satoshi, Ohkawara Hiroshi, Yamada Shingo, Ito Takashi, Ikezoe Takayuki

    International journal of hematology   111 ( 3 )   378 - 387   2020.3( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s12185-019-02798-5

    PubMed

  • Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors.

    Kimura S, Ohkawara H, Minakawa K, Fukatsu M, Mori H, Takahashi H, Harada-Shirado K, Ohara Y, Takahashi N, Mochizuki K, Sano H, Nollet KE, Ogawa K, Ohto H, Kikuta A, Ikeda K, Ikezoe T

    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis   102737   2020.2( ISSN:1473-0502

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.transci.2020.102737

    PubMed

  • The link between interleukin-1β and acute myocardial infarction in chronic myeloid leukemia patients treated with nilotinib: cross-sectional study.

    Mori H, Sukegawa M, Fukatsu M, Sano T, Takahashi H, Harada K, Kimura S, Ohkawara H, Nakamura K, Mita M, Saito T, Hamazaki Y, Ohta M, Ikezoe T

    Annals of hematology   99 ( 2 )   359 - 361   2020.2( ISSN:0939-5555

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s00277-019-03896-4

    PubMed

  • The link between interleukin-1β and acute myocardial infarction in chronic myeloid leukemia patients treated with nilotinib: cross-sectional study.

    Hirotaka Mori, Masumi Sukegawa, Masahiko Fukatsu, Takahiro Sano, Hiroshi Takahashi, Kayo Harada, Satoshi Kimura, Hiroshi Ohkawara, Kenichi Nakamura, Masayuki Mita, Tomiyoshi Saito, Yoichi Hamazaki, Masatsugu Ohta, Takayuki Ikezoe

    Annals of hematology   99 ( 2 )   359 - 361   2020.2( ISSN:0939-5555

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s00277-019-03896-4

    PubMed

  • Integral role of receptor for advanced glycation end products(RAGE) in nondiabetic atherosclerosis(和訳中)

    Uekita Hironori, Ishibashi Toshiyuki, Shiomi Masashi, Koyama Hidenori, Ohtsuka Shukuko, Yamamoto Hiroshi, Yamagishi Shoichi, Inoue Hiroyoshi, Itabe Hiroyuki, Sugimoto Koichi, Kamioka Masashi, Ohkawara Hiroshi, Wada Ikuo, Takeishi Yasuchika

    Fukushima Journal of Medical Science   65 ( 3 )   109 - 121   2020.1( ISSN:0016-2590

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Integral role of receptor for advanced glycation end products (RAGE) in nondiabetic atherosclerosis

    Hironori Uekita, Toshiyuki Ishibashi, Masashi Shiomi , Hidenori Koyama, Shukuko Ohtsuka, Hiroshi Yamamoto, Shoichi Yamagishi, Hiroyoshi Inoue, Hiroyuki Itabe, Koichi Sugimoto, Masashi Kamioka, Hiroshi Ohkawara, Ikuo Wada, Takeishi Yasuchika.

    Fukushima Journal of Medical Science   65 ( 3 )   109 - 121   2019.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.5387/fms.2019-12

    PubMed

  • Intestinal Behçet disease associated with myelodysplastic syndrome accompanying trisomy 8 successfully treated with abdominal surgery followed by hematopoietic stem cell transplantation: A case report.

    Asano T, Sato S, Furuya MY, Takahashi H, Shichishima-Nakamura A, Ohkawara H, Fujiwara T, Gunji N, Hashimoto C, Momma T, Saito M, Nakano H, Watanabe G, Temmoku J, Fujita Y, Matsuoka N, Kobayashi H, Watanabe H, Mouri M, Mashiyama F, Sakuma H, Ohira H, Mori M, Ikezoe T, Migita K

    Medicine   98 ( 46 )   e17979   2019.11( ISSN:0025-7974

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1097/MD.0000000000017979

    PubMed

  • A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD.

    Furukawa M, Wang X, Ohkawara H, Fukatsu M, Alkebsi L, Takahashi H, Harada-Shirado K, Shichishima-Nakamura A, Kimura S, Ogawa K, Ikezoe T

    Blood advances   3 ( 14 )   2128 - 2143   2019.7( ISSN:2473-9529

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1182/bloodadvances.2019000222

    PubMed

  • 造血器腫瘍と免疫・凝固系 第4回 造血幹細胞移植後の免疫凝固異常

    大河原 浩, 池添 隆之

    Thrombosis Medicine   9 ( 1 )   60 - 66   2019.3( ISSN:2186-0327

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Predicting factors of transmural thermal injury after cryoballoon pulmonary vein isolation.

    Matsumoto Y, Kaneshiro T, Hijioka N, Nodera M, Yamada S, Kamioka M, Yoshihisa A, Ohkawara H, Hikichi T, Suzuki H, Takeishi Y

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing   54 ( 2 )   101 - 108   2019.3( ISSN:1383-875X

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s10840-018-0454-8

    PubMed

  • Lenalidomide as a Beneficial Treatment Option for Renal Impairment Caused by Light Chain Deposition Disease

    Kimura Satoshi, Ohkawara Hiroshi, Ogawa Kazuei, Tanaka Mizuko, Sano Takahiro, Harada-Shirado Kayo, Takahashi Hiroshi, Ueda Koki, Shichishima-Nakamura Akiko, Matsumoto Hayato, Ikeda Kazuhiko, Kazama Junichiro James, Hashimoto Yuko, Ikezoe Takayuki

    Internal Medicine   57 ( 24 )   3651 - 3657   2018.12( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Distinct Forms of Esophageal Lesions After Radiofrequency and Cryoballoon Pulmonary Vein Isolation.

    Kaneshiro T, Matsumoto Y, Hijioka N, Nodera M, Yamada S, Kamioka M, Yoshihisa A, Ohkawara H, Suzuki H, Takeishi Y

    JACC. Clinical electrophysiology   4 ( 12 )   1642 - 1643   2018.12( ISSN:2405-500X

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.jacep.2018.08.006

    PubMed

  • Lenalidomide as a Beneficial Treatment Option for Renal Impairment Caused by Light Chain Deposition Disease: A Case Series

    Kimura Satoshi, Matsumoto Hayato, Ikeda Kazuhiko, Kazama Junichiro James, Hashimoto Yuko, Ikezoe Takayuki, Ohkawara Hiroshi, Ogawa Kazuei, Tanaka Mizuko, Sano Takahiro, Harada-Shirado Kayo, Takahashi Hiroshi, Ueda Koki, Shichishima-Nakamura Akiko

    Internal medicine (Tokyo, Japan)   2018.8( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.2169/internalmedicine.1018-18

    PubMed

  • 気管に限局して発症し気管閉塞を来たした節外性NK/T細胞リンパ腫、鼻型

    高橋 裕志, 大河原 浩, 七島 晶子, 深津 真彦, 佐野 隆浩, 原田 佳代, 木村 哲, 東川 隆一, 田崎 和洋, 橋本 優子, 小川 一英, 池添 隆之

    臨床血液   59 ( 8 )   1012 - 1015   2018.8( ISSN:0485-1439

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 気管に限局して発症し気管閉塞を来たした節外性NK/T細胞リンパ腫、鼻型

    高橋 裕志, 大河原 浩, 七島 晶子, 深津 真彦, 佐野 隆浩, 原田 佳代, 木村 哲, 東川 隆一, 田崎 和洋, 橋本 優子, 小川 一英, 池添 隆之

    臨床血液   59 ( 8 )   1012 - 1015   2018.8( ISSN:0485-1439

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • A case of TAFRO syndrome successfully treated with cyclosporin A and tocilizumab

    Asano Tomoyuki, Yashiro Makiko, Watanabe Aya, Sato Shuzo, Kobayashi Hiroko, Watanabe Hiroshi, Ohkawara Hiroshi, Murakami Fumi, Hashimoto Yuko, Koga Tomohiro, Kawakami Atsushi, Migita Kiyoshi

    Modern Rheumatology Case Reports   2 ( 2 )   209 - 213   2018.7

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain.

    Wang X, Pan B, Honda G, Wang X, Hashimoto Y, Ohkawara H, Xu K, Zeng L, Ikezoe T

    Haematologica   2018.6( ISSN:0390-6078

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3324/haematol.2017.184481

    PubMed

  • Defibrotide Stimulates Angiogenesis and Protects Endothelial Cells from Calcineurin Inhibitor-Induced Apoptosis via Upregulation of AKT/Bcl-xL.

    Wang X, Pan B, Hashimoto Y, Ohkawara H, Xu K, Zeng L, Ikezoe T

    Thrombosis and haemostasis   118 ( 1 )   161 - 173   2018.1( ISSN:0340-6245

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1160/TH17-04-0275

    PubMed

  • Anatomical predisposing factors of transmural thermal injury after pulmonary vein isolation

    Takashi Kaneshiro, Yoshiyuki Matsumoto, Minoru Nodera, Masashi Kamioka, Yoshiyuki Kamiyama, Akiomi Yoshihisa, Hiroshi Ohkawara, Hitoshi Suzuki, Yasuchika Takeishi

    Europace   20 ( (7) )   1122 - 1128   2018

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Distinct forms of esophageal lesions after radiofrequency and cryoballoon pulmonary vein isolation

    Takashi Kaneshiro, Yoshiyuki Matsumoto, Naoko Hijioka, Minoru Nodera, Shinya Yamada, Masashi Kamioka, Akiomi Yoshihisa, Hiroshi Ohkawara, Hitoshi Suzuki, Yasuchika Takeishi

    JACC: Clinical Electrophysiology   4 ( (12) )   1642 - 1643   2018

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Airway obstruction due to localized tracheal lesion of extranodal NK/T-cell lymphoma, nasal type

    TAKAHASHI Hiroshi, HASHIMOTO Yuko, OGAWA Kazuei, IKEZOE Takayuki, OHKAWARA Hiroshi, SHICHISHIMA-NAKAMURA Akiko, FUKATSU Masahiko, SANO Takahiro, HARADA-SHIRADO Kayo, KIMURA Satoshi, TOGAWA Ryuichi, TASAKI Kazuhiro

    Rinsho Ketsueki   59 ( 8 )   1012 - 1015   2018( ISSN:0485-1439

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.11406/rinketsu.59.1012

    PubMed

  • Steroid-resistant autoimmune myelofibrosis in a patient with autoimmune hepatitis and Evans syndrome complicated with increased expression of TGF-β in the bone marrow: a case report.

    Ohkawara H, Furukawa M, Ikeda K, Shichishima-Nakamura A, Fukatsu M, Sano T, Ueda K, Kimura S, Kanai R, Oka Y, Murakami F, Suzuki O, Hashimoto Y, Ogawa K, Ikezoe T

    International journal of hematology   106 ( 5 )   718 - 724   2017.11( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s12185-017-2268-3

    PubMed

  • Steroid-resistant autoimmune myelofibrosis in a patient with autoimmune hepatitis and Evans syndrome complicated with increased expression of TGF-β in the bone marrow: a case report(和訳中)

    Ohkawara Hiroshi, Furukawa Miki, Ikeda Kazuhiko, Shichishima-Nakamura Akiko, Fukatsu Masahiko, Sano Takahiro, Ueda Koki, Kimura Satoshi, Kanai Risa, Oka Yuka, Murakami Fumi, Suzuki Osamu, Hashimoto Yuko, Ogawa Kazuei, Ikezoe Takayuki

    International Journal of Hematology   106 ( 5 )   718 - 724   2017.11( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • The BCR/ABL tyrosine kinase inhibitor, nilotinib, stimulates expression of IL-1β in vascular endothelium in association with downregulation of miR-3p.

    Sukegawa M, Wang X, Nishioka C, Pan B, Xu K, Ohkawara H, Hamasaki Y, Mita M, Nakamura K, Okamoto M, Shimura H, Ohta M, Ikezoe T

    Leukemia research   58   83 - 90   2017.7( ISSN:0145-2126

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.leukres.2017.05.005

    PubMed

  • Hmga2 collaborates with <i>JAK2</i>V617F in the development of myeloproliferative neoplasms.

    Ueda K, Ikeda K, Ikezoe T, Harada-Shirado K, Ogawa K, Hashimoto Y, Sano T, Ohkawara H, Kimura S, Shichishima-Nakamura A, Nakamura Y, Shikama Y, Mori T, Mason PJ, Bessler M, Morishita S, Komatsu N, Shide K, Shimoda K, Koide S, Aoyama K, Oshima M, Iwama A, Takeishi Y

    Blood advances   1 ( 15 )   1001 - 1015   2017.6( ISSN:2473-9529

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1182/bloodadvances.2017004457

    PubMed

  • Anatomical predisposing factors of transmural thermal injury after pulmonary vein isolation.

    Kaneshiro T, Matsumoto Y, Nodera M, Kamioka M, Kamiyama Y, Yoshihisa A, Ohkawara H, Suzuki H, Takeishi Y

    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology   2017.6( ISSN:1099-5129

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1093/europace/eux185

    PubMed

  • Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms

    Koki Ueda, Kazuhiko Ikeda, Takayuki Ikezoe, Kayo Harada-Shirado, Kazuei Ogawa, Yuko Hashimoto, Takahiro Sano, Hiroshi Ohkawara, Satoshi Kimura, Akiko Shichishima-Nakamura, Yuichi Nakamura, Yayoi Shikama, Tsutomu Mori, Philip J. Mason, Monica Bessler, Soji Morishita, Norio Komatsu, Kotaro Shide, Kazuya Shimoda, Shuhei Koide, Kazumasa Aoyama, Motohiko Oshima, Atsushi Iwama, Yasuchika Takeishi

    blood advances   1 ( 15 )   1001 - 1015   2017.6

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • A possible role of low regulatory T cells in anti-acetylcholine receptor antibody positive myasthenia gravis after bone marrow transplantation.

    Fukatsu M, Murakami T, Ohkawara H, Saito S, Ikeda K, Kadowaki S, Sasaki I, Segawa M, Soeda T, Hoshi A, Takahashi H, Shichishima-Nakamura A, Ogawa K, Sugiura Y, Ohto H, Takeishi Y, Ikezoe T, Ugawa Y

    BMC neurology   17 ( 1 )   93   2017.5

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1186/s12883-017-0881-7

    PubMed

  • Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6.

    Furukawa M, Ohkawara H, Ogawa K, Ikeda K, Ueda K, Shichishima-Nakamura A, Ito E, Imai JI, Yanagisawa Y, Honma R, Watanabe S, Waguri S, Ikezoe T, Takeishi Y

    The Journal of biological chemistry   292 ( 10 )   4280 - 4292   2017.3( ISSN:0021-9258

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1074/jbc.M116.733030

    PubMed

  • A possible role of low regulatory T cells in anti-acetylcholine receptor antibody positive myasthenia gravis after bone marrow transplantation

    Masahiko Fukatsu, Takenobu Murakami, Hiroshi Ohkawara, Shunichi Saito, Kazuhiko Ikeda, Suguru Kadowaki, Itaru Sasaki, Mari Segawa, Tomoko Soeda, Akihiko Hoshi, Hiroshi Takahashi, Akihiko Shichishima-Nakamura, Kazuei Ogawa, Yoshihiro Sugita, Hitoshi Ohto, Yasuchika Takeishi, Takayuki Ikezoe, Yoshikazu Ugawa

    BMC Neurology   17 ( 1 )   93   2017

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Infected pancreatic pseudocyst ruptured into stomach and colon associated with splenic artery pseudoaneurysm

    OHKAWARA, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; IKEDA, Kazuhiko*; SUKEGAWA, Masumi*; FURUKAWA, Miki*; SANO, Takahiro*; UEDA, Koki*; KIMURA, Satoshi*; YOSHIHISA, Akiomi*; NOJI, Hideyoshi*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    Journal of the Pancreas   17 ( 3 )   324 - 327   2016

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • MT1-MMP)(MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE(MT1-MMP) IDENTIFIED AS A MULTIFUNCTIONAL REGULATOR OF VASCULAR RESPONSES

    Ohkawara Hiroshi, Ikeda Kazuhiko, Ogawa Kazuei, Takeishi Yasuchika

    Fukushima Journal of Medical Science   61 ( 2 )   91 - 100   2015.12( ISSN:0016-2590

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Persistent complete remission of acute leukemic-phase CCR4-positive gamma-delta peripheral T-cell lymphoma by autologous stem cell transplantation with mogamulizumab

    Furukawa Miki, Ikeda Kazuhiko, Ohkawara Hiroshi, Saito Shunichi, Takahashi Hiroshi, Udea Koki, Matsumoto Hayato, Hashimoto Yuko, Ohto Hitoshi, Ogawa Kazuei, Takeishi Yasuchika

    International Journal of Hematology   102 ( 4 )   498 - 505   2015.10( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Membrane type 1-matrix metalloproteinase (MT1-MMP) identified as a multifunctional regulator of vascular responses

    OHKAWARA, Hiroshi*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    Fukushima Journal of Medical Science   61 ( 2 )   91 - 100   2015.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.5387/fms.2015-15

  • Erratum to: Persistent complete remission of acute leukemic-phase CCR4-positive gamma-delta peripheral T-cell lymphoma by autologous stem cell transplantation with mogamulizumab.

    Furukawa M, Ikeda K, Ohkawara H, Saito S, Takahashi H, Ueda K, Matsumoto H, Hashimoto Y, Ohto H, Ogawa K, Takeishi Y

    International journal of hematology   102 ( 1 )   147   2015.7( ISSN:0925-5710

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/s12185-015-1817-x

    PubMed

  • Persistent complete remission of acute leukemic-phase CCR4-positive gamma-delta peripheral T-cell lymphoma by autologous stem cell transplantation with mogamulizumab

    FURUKAWA, Miki*; IKEDA, Kazuhiko*; OHKAWARA, Hiroshi*; SAITO, Shunichi*; TAKAHASHI, Hiroshi*; UEDA, Koki*; MATSUMOTO, Hayato*; HASHIMOTO, Yuko*; OHTO, Hitoshi*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    International Journal of Hematology   102 ( 4 )   498 - 505   2015.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1007/s12185-015-1805-1

  • Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms

    HARADA-SHIRADO, Kayo*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; OHKAWARA, Hiroshi*; KIMURA, Hideo; KAI, Tatsuyuki; NOJI, Hideyoshi*; MORISHITA, Soji; KOMATSU, Norio; TAKEISHI, Yasuchika*

    British Journal of Haematology   168 ( 3 )   338 - 349   2015

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1111/bjh.13129

  • CD4+ T cells in aged or thymectomized recipients of allogenic stem cell transplantations

    TAKAHASHI, Hiroshi*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; SAITO, Syunnichi*; NGOMA, Alain*; MASHIMO, Yumiko*; UEDA, Koki*; FURUKAWA, Miki*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; NOLLET, Kenneth*; OHTO, Hitoshi*; TAKEISHI, Yasuchika*

    Biological Research   48   41   2015

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1186/s40659-015-0033-8

  • Post-engraftment blood transfusion and outcomes of bone marrow transplantation

    MASHIMO, Yumiko*; IKEDA, Kazuhiko*; OHKAWARA, Hiroshi*; TAKAHASHI, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; FURUKAWA, Miki*; KIMURA, Satoshi*; UEDA, Koki*; NOJI, Hideyoshi*; OGAWA, Kazuei*; NOLLET, Kenneth*; OHTO, Hitoshi*; TAKEISHI, Yasuchika*

    ISBT Science Series   10 ( 2 )   93 - 99   2015

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1111/voxs.12230

  • Severe Immune Thrombocytopenia Possibly Elicited by the Anti-influenza Viral Agent Peramivir

    Harada-Shirado Kayo, Ikeda Kazuhiko, Furukawa Miki, Sukegawa Masumi, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Ohkawara Hiroshi, Noji Hideyoshi, Kawabata Kinuyo, Saito Shun-ichi, Ohto Hitoshi, Ogawa Kazuei, Takeishi Yasuchika

    Internal Medicine   53 ( 20 )   2369 - 2371   2014.10( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Pleural Solitary Fibrous Tumor Complicated with Autoimmune Hemolytic Anemia

    Takahashi Hiroaki, Ohkawara Hiroshi, Ikeda Kazuhiko, Harada-Shirado Kayo, Furukawa Miki, Sukegawa Masumi, Shichishima-Nakamura Akiko, Noji Hideyoshi, Wakamatsu Saho, Tasaki Kazuhiro, Suzuki Hiroyuki, Ogawa Kazuei, Takeishi Yasuchika

    Internal Medicine   53 ( 14 )   1549 - 1552   2014.7( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • 当院における遺伝子組換えトロンボモジュリン製剤の使用経験

    松本 勇人, 古川 未希, 原田 佳代, 高橋 裕志, 七島 晶子, 大河原 浩, 池田 和彦, 野地 秀義, 小川 一英, 竹石 恭知

    東北止血・血栓研究会会誌   XXVI ( 1 )   4 - 5   2014.5( ISSN:0914-6598

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Somatic 15q break after long-term stable disease in acute myeloid leukemia

    HARADA-SHIRADO, Kayo*; IKEDA, Kazuhiko*; MATSUMOTO, Hayato*; SHIGA, Yutaka; FURUKAWA, Miki*; TAKAHASHI, Hiroshi*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; HASHIMOTO, Yuko*; WAGURI, Satoshi*; WATANABE, Shinya*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    Clinical Lymphoma, Myeloma & Leukemia   14 ( 2 )   e69-e72   2014

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1016/j.clml.2013.10.009

  • Pleural solitary fibrous tumor complicated with autoimmune hemolytic anemia

    TAKAHASHI, Hiroshi*; OHKAWARA, Hiroshi*; IKEDA, Kazuhiko*; HARADA-SHIRADO, Kayo*; FURUKAWA, Miki*; SUKEGAWA, Masumi*; SHICHISHIMA-NAKAMURA, Akiko*; NOJI, Hideyoshi*; WAKAMATSU, Saho; TASAKI*, Kazuhiro; SUZUKI*, Hiroyuki; OGAWA*, Kazuei*; TAKEISHI, Yasuchika*

    Internal Medicine   53 ( 14 )   1549 - 1552   2014

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.2169/internalmedicine.53.2121

  • Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells

    OHKAWARA, Hiroshi*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    PLoS One   9 ( 8 )   e105697   2014

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1371/journal.pone.0105697

  • Severe immune thrombocytopenia possibly elicited by the anti-influenza viral agent peramivir

    HARADA-SHIRADO, Kayo*; IKEDA, Kazuhiko*; FURUKAWA, Miki*; SUKEGAWA, Masumi*; TAKAHASHI, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; KAWABATA, Kinuyo; SAITO, Shun-ichi; OHTO, Hitoshi; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    Internal Medicine   53 ( 10 )   2369 - 2371   2014

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.2169/internalmedicine.53.2330

  • Receptor for advanced glycation end products - membrane type1 matrix metalloproteinase axis regulates tissue factor expression via RhoA and Rac1 activation in high-mobility group box-1 stimulated endothelial cells

    SUGIMOTO, Koichi*; OHKAWARA, Hiroshi*; NAKAMURA, Yuichi*; TAKUWA, Yoh; ISHIBASHI, Toshiyuki*; TAKEISHI, Yasuchika*

    PLoS One   9 ( 12 )   e114429   2014

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1371/journal.pone.0114429

  • Severe immune thrombocytopenia possibly elicited by the anti-influenza viral agent peramivir.

    Harada-Shirado K, Ikeda K, Furukawa M, Sukegawa M, Takahashi H, Shichishima-Nakamura A, Ohkawara H, Noji H, Kawabata K, Saito S, Ohto H, Ogawa K, Takeishi Y

    Internal medicine (Tokyo, Japan)   53 ( 20 )   2369 - 71   2014( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  • Pleural solitary fibrous tumor complicated with autoimmune hemolytic anemia.

    Takahashi H, Ohkawara H, Ikeda K, Harada-Shirado K, Furukawa M, Sukegawa M, Shichishima-Nakamura A, Noji H, Wakamatsu S, Tasaki K, Suzuki H, Ogawa K, Takeishi Y

    Internal medicine (Tokyo, Japan)   53 ( 14 )   1549 - 52   2014( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  • Pulmonary Hypertension and Refractory Heart Failure in a Patient with Crow-Fukase (POEMS) Syndrome

    Yokokawa Tetsuro, Nakazato Kazuhiko, Kanno Yuki, Mizukami Hiroyuki, Kobayashi Atsushi, Yoshihisa Akiomi, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Ohkawara Hiroshi, Noji Hideyoshi, Suzuki Hitoshi, Saitoh Shu-ichi, Ogawa Kazuei, Hisa Shinichi, Takeishi Yasuchika

    Internal Medicine   52 ( 10 )   1061 - 1065   2013.5( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

  • Pulmonary hypertension and refractory heart failure in a patient with Crow-Fukase (POEMS) syndrome

    YOKOKAWA, Tetsuro*; NAKAZATO, Kazuhiko*; KANNO, Yuki*; MIZUKAMI, Hiroyuki*; KOBAYASHI, Atsushi*; YOSHIHISA, Akiomi*; TAKAHASHI, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; SUZUKI, Hitoshi*; SAITOH, Shu-ichi*; OGAWA, Kazuei*; HISA, Shinichi; TAKEISHI, Yasuchika*

    Internal Medicine   52 ( 10 )   1061 - 1065   2013

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.2169/internalmedicine.52.9256

  • Pulmonary hypertension and refractory heart failure in a patient with Crow-Fukase (POEMS) syndrome.

    Yokokawa T, Nakazato K, Kanno Y, Mizukami H, Kobayashi A, Yoshihisa A, Takahashi H, Shichishima-Nakamura A, Ohkawara H, Noji H, Suzuki H, Saitoh S, Ogawa K, Hisa S, Takeishi Y

    Internal medicine (Tokyo, Japan)   52 ( 10 )   1061 - 5   2013( ISSN:0918-2918

      More details

    Language:English   Publishing type:Research paper (scientific journal)  

    PubMed

  • A Japanese case of chronic lymphocytic leukemia with t(1;6)

    HARADA, Kayo*; IKEDA, Kazuhiko*; MATSUMOTO, Hayato*; FURUKAWA, Miki*; TAKAHASHI, Hiroshi*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; TASAKI, Kazuhiro; ABE, Masafumi; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

    Experimental Hematology & Oncology   1 ( 1 )   28   2012

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1186/2162-3619-1-28

  • 特集 動脈硬化研究の最新知見 動脈硬化の発症・進展における酸化ストレスの役割

    大河原浩*, 竹石恭知*

    2 ( 4 )   252 - 257   2011

      More details

    Language:Japanese   Publishing type:Research paper (other academic)  

  • Involvement of membrane type 1-matrix metalloproteinase (MT1-MMP) in RAGE activation signaling pathways

    KAMIOKA, Masashi*; ISHIBASHI, Toshiyuki*; OHKAWARA, Hiroshi*; NAGAI, Ryoji; SUGIMOTO, Koichi*; UEKITA, Hironori*; MATSUI, Takanori; YAMAGISHI, Sho-ichi; ANDO, Katsuya*; SAKAMOTO, Takayuki*; TAKUWA, Yoh; WADA, Ikuo; SHIOMI, Masashi; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

    Journal of Cellular Physiology   226 ( 6 )   1554 - 1563   2011

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Crucial role of membrane type 1 matrix metalloproteinase (MT1-MMP) in RhoA/Rac1-dependent signaling pathways in thrombin-stimulated endothelial cells

    ANDO, Katuya*; ISHIBASHI, Toshiyuki*; OHKAWARA, Hiroshi*; INOUE, Nobutaka; SUGIMOTO, Koichi*; UEKITA, Hironori*; HU, Chengjun; OKAMOTO, Yasuo; TAKUWA, Yoh; TAKEISHI, Yasuchika*

    Journal of Atherosclerosis and Thrombosis   18 ( 9 )   762 - 773   2011

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Preventive effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by repeated epicardial coronary artery endothelial denudation in pigs

    OSUGI, Taku*; SAITOH, Shu-ichi*; MATSUMOTO, Ken*; MUTO, Mitsuru*; AIKAWA, Kazuhiko*; OHKAWARA, Hiroshi*; SUGIMOTO, Koichi*; KAMIOKA, Masashi*; ISHIBASHI, Toshiyuki*; MARUYAMA, Yukio*

    Journal of Atherosclerosis and Thrombosis   17 ( 1 )   54 - 63   2010

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Blockade of renin-angiotensin system attenuates advanced glycation end products-mediated signaling pathways

    KAMIOKA, Masashi*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; UEKITA, Hironori*; NAGAI, Ryoji; SAKAMOTO, Nobuo*; ANDO, Katsuya*; OHKAWARA, Hiroshi*; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

    Journal of Atherosclerosis and Thrombosis   17 ( 6 )   590 - 600   2010

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Preventive effects of pravastatin on thrombin-triggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo

    OHKAWARA, Hiroshi*; ISHIBASHI, Toshiyuki*; SAITOH, Shu-ichi*; INOUE, Nobutaka; SUGIMOTO, Koichi*; KAMIOKA, Masashi*; UEKITA, Hironori*; KANESHIRO, Takashi*; ANDO, Katsuya*; TAKUWA, Yoh; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

    Cardiovascular Research   88 ( 3 )   492 - 501   2010

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Hematopoietic stem cell transplantation in the Department of Hematology, Fukushima Medical University

    OGAWA, Kazuei*; NOJI, Hideyoshi*; FURUKAWA, Miki*; HARADA-SHIRADO, Kayo*; MASHIMO, Yumiko*; TAKAHASHI, Hiroshi*; MATSUMOTO, Hayato*; KIMURA, Satoshi*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; IKEDA, Kazuhiko*; OHTO, Hitoshi; TAKEISHI, Yasuchika*

    Fukushima Journal of Medical Science   56 ( 2 )   107 - 114   2010

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • A long-term remission of renal amyloidosis with nephrotic syndrome after autologous peripheral blood stem-cell transplantation

    OGAWA, Kazuei*; IKEDA, Kazuhiko*; FURUKAWA, Miki*; HARADA-SHIRADO, Kayo*; MASHIMO, Yumiko*; TAKAHASHI, Hiroshi*; MATSUMOTO, Hayato*; KIMURA, Satoshi*; SHICHISHINA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; HASHIMOTO, Yuko; ASAHI, Koichi; NOJI, Hideyoshi*; OHTO, Hitoshi; TAKEISHI, Yasuchika*

    Fukushima Journal of Medical Science   56 ( 2 )   151 - 156   2010

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Bone marrow-derived progenitor cells prevent thrombin-induced increase in lung vascular permeability

    ZHAO, Yidan; OHKAWARA, Hiroshi*; VOGEL, Stephen; MALIK, Asrar; ZHAO, You-Yang Y. D. Zhao and H. Ohkawara contributed equally to this study.

    American Journal of Physiology Lung Cellular and Molecular Physiology   298 ( 1 )   L36-L44   2010

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1152/ajplung.00064.2009

  • Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+ signaling pathways in endothelial cells

    SAKAMOTO, Nobuo*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; SAWAMURA, Tatsuya; SAKAMOTO, Takayuki*; INOUE, Nobutaka; SAITOH, Shu-ichi*; KAMIOKA, Masashi*; UEKITA, Hironori*; OHKAWARA, Hiroshi*; SUZUKI, Koji; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

    Journal of Cellular Physiology   220 ( 3 )   706 - 715   2009

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells

    SUGIMOTO, Koichi*; ISHIBASHI, Toshiyuki*; SAWAMURA, Tatsuya; INOUE, Nobutaka; KAMIOKA, Masashi*; UEKITA, Hironori*; OHKAWARA, Hiroshi*; SAKAMOTO, Takayuki*; SAKAMOTO, Nobuo*; OKAMOTO, Yasuo; TAKUWA, Yoh; KAKINO, Akemi; FUJITA, Yoshiki; TANAKA, Takashi; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

    Cardiovascular Research   84 ( 1 )   127 - 136   2009

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Novel pathway of endothelin-1 and reactive oxygen species in coronary vasospasm with endothelial dysfunction

    SAITOH, Shu-ichi*; MATSUMOTO, Ken*; KAMIOKA, Masashi*; OHKAWARA, Hiroshi*; KANESHIRO, Takashi*; ISHIBASHI, Toshiyuki*; MARUYAMA, Yukio*

    Coronary Artery Disease   20 ( 6 )   400 - 408   2009

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • RhoA and Rac1 changes in the atherosclerotic lesions of WHHLMI rabbits

    OHKAWARA, Hiroshi*; ISHIBASHI, Toshiyuki*; SHIOMI, Masashi; UEKITA, Hironori*; KAMIOKA, Masashi*; TAKUWA, Yoh; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

    Journal of Atherosclerosis and Thrombosis   16 ( 6 )   846 - 856   2009

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling

    ZHAO, Yidan; OHKAWARA, Hiroshi*; REHMAN, Jalees; WARY, Kishore; VOGEL, Stephen; MINSHALL, Richard; ZHAO, You-Yang; MALIK, Asrar

    Circulation Research   105 ( 77 )   696 - 704   2009

      More details

    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1161/CIRCRESAHA.109.199778

  • RhoA-dependent PAI-1 gene expression induced in endothelial cells by monocyte adhesion mediates geranylgeranyl transferase I and Ca2+ signaling

    SAKAMOTO, Takayuki*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; SAKAMOTO, Nobuo*; OHKAWARA, Hiroshi*; NIINUMA, Miki*; NAGATA, Kenji*; KAMIOKA, Masashi*; SUGIMOTO, Naotoshi; WATANABE, Atai; KURABAYASHI, Masahiko; TAKUWA, Yoh; MARUYAMA, Yukio*

    Atherosclerosis   193 ( 1 )   44 - 54   2007.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Low serum ferritin levels as a clue to colonic cancer detection in two patients with coronary artery disease: a case report.

    Yaoita H, Ohkawara H, Uekita H, Mitsugi M, Tajima H, Kaneko H, Hoshino Y, Otani S, Gotoh M, Maruyama Y.

    Fukushima J Med Sci.   51 ( 2 )   95 - 104   2005.12

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Endogenous NO blockade enhances tissue factor expression via increased Ca2+ influx through MCP-1 in endothelial cells by monocyte adhesion.

    Sakamoto T, Ishibashi T, Sakamoto N, Sugimoto K, Egashira K, Ohkawara H, Nagata K, Yokoyama K, Kamioka M, Ichiki T, Sugimoto N, Kurabayashi M, Suzuki K, Takuwa Y, Maruyama Y.

    Arterioscler Thromb Vasc Biol.   25 ( 9 )   2005 - 2011   2005.9

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.

    Ohkawara H, Ishibashi T, Sakamoto T, Sugimoto K, Nagata K, Yokoyama K, Sakamoto N, Kamioka M, Matsuoka I, Fukuhara S, Sugimoto N, Takuwa Y, Maruyama Y.

    J Biol Chem.   280 ( 11 )   10182 - 10188   2005.3

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Integral role of RhoA activation in monocyte adhesion-triggered tissue factor expression in endothelial cells.

    Ishibashi T, Sakamoto T, Ohkawara H, Nagata K, Sugimoto K, Sakurada S, Sugimoto N, Watanabe A, Yokoyama K, Sakamoto N, Kurabayashi M, Takuwa Y, Maruyama Y.

    Arterioscler Thromb Vasc Biol.   23 ( 4 )   681 - 687   2003.4

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes

    Nagata K, Ishibashi T, Sakamoto T, Ohkawara H, Shindo J, Yokoyama K, Sugimoto K, Sakurada S, Takuwa Y, Nakamura S, Teramoto T, Maruyama Y.

    Atherosclerosis.   163 ( 1 )   39 - 47   2002.7

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes.

    Ishibashi T, Nagata K, Ohkawara H, Sakamoto T, Yokoyama K, Shindo J, Sugimoto K, Sakurada S, Takuwa Y, Teramoto T, Maruyama Y.

    Biochim Biophys Acta.   1590 ( 1-3 )   123 - 130   2002.6

      More details

    Language:English   Publishing type:Research paper (other academic)  

  • HMG-CoA reductase inhibitors suppress intracellular calcium mobilization and membrane current induced by lysophosphatidylcholine in endothelial cells.

    Yokoyama K, Ishibashi T, Ohkawara H, Kimura J, Matsuoka I, Sakamoto T, Nagata K, Sugimoto K, Sakurada S, Maruyama Y.

    Circulation.   105 ( 8 )   962 - 967   2002.2

      More details

    Language:English   Publishing type:Research paper (other academic)  

▼display all

Presentations

  • HMGA2 orchestrates the tumorgenesis of myeloproliferative neoplasms (MPN) in corporation with JAK2V617F

    58th American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2016.12

  • 同種造血幹細胞移植におけるボリコナゾールおよびキャンディン系抗真菌薬予防投与の有効性に関する後方視的解析

    第8回 県北感染症診断・治療研究会  

      More details

    Event date: 2016.11

  • 末梢神経障害で発症した原発性マクログロブリン血症の一例

    第32回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2016.11

  • 末梢神経障害で発症した原発性マクログロブリン血症の一例

    第32回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2016.11

  • Autocrine and paracrine interactions by Gas 6 signaling pathways via IL-6 between MM cells and BMSCs

      More details

    Event date: 2016.10

  • 多発性骨髄腫の化学療法20 年後に発症した門脈肺高血圧症の一例

    第16回 肺高血圧治療談話会  

      More details

    Event date: 2016.10

  • 同種造血幹細胞移植後の肝障害の診断に肝生検が有用であった二次性ヘモクロマトリーシスの一例

    第122回 日本血液学会東北地方会  

      More details

    Event date: 2016.9

  • 手術と薬物療法の追加で、新鮮凍結血漿輸血を大幅に削減できた大動脈解離による慢性DIC症例

    第109回 日本輸血・細胞治療学会 東北支部例会  

      More details

    Event date: 2016.9

  • 手術、薬物療法の追加で、新鮮凍結血漿輸血を、大幅に削減できた大動脈解離による慢性DIC症例

    第63回 福島血液研究会  

      More details

    Event date: 2016.7

  • 同種造血幹細胞移植後の肝障害の診断に肝生検が有用であった二次性ヘモクロマトリーシスの一例

    第63回 福島血液研究会  

      More details

    Event date: 2016.7

  • The prevalence of transmural thermal injury after pulmonary vein isolation is associated with the anatomical situations surrounding the esophagus

      More details

    Event date: 2016.7

  • 全身の骨病変をきたしたCD5陽性DLBCLの一例

    第22回 造血器腫瘍研究会  

      More details

    Event date: 2016.4

  • Anatomical relationship among esophagus, left atrium and descending aorta is associated with the transmural thermal injury after pulmonary vein isolation

      More details

    Event date: 2016.3

  • Clininal study of CD4+T cell in aged recipients of allogenic stem cell transplantations

      More details

    Event date: 2016.3

  • 非血縁者間同種造血幹細胞移植後に発症した重症筋無力症の一例

    第121回 日本血液学会東北地方会  

      More details

    Event date: 2016.2

  • 非血縁者間同種造血幹細胞移植後に発症した重症筋無力症の一例

    第121回 日本血液学会東北地方会  

      More details

    Event date: 2016

  • Autocrine and paracrine regulatory mechanisms of growth arrest-specific Gene 6 contribute to disease progression of multiple myeloma

    57th American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2015.12

  • EBV関連LPDとIgG4関連疾患を合併しRituximabが有効であった1例

    第31回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2015.11

  • Autocrine and paracrine regulation by Gas 6 contributes to multiple myeloma disease progression

      More details

    Event date: 2015.10

  • Persistent CR of acute leukemic-phase CCR4+γδ PTCL-NOS by auto-PBSCT with mogamulizumab

      More details

    Event date: 2015.10

  • Dysregulation of let-7/HMGA2 axis can be a target of histone deacetylase inhibitor in MPNs

      More details

    Event date: 2015.10

  • Transfusions after engraftment associate with non-relapse mortality in the setting of allo-HSCT

      More details

    Event date: 2015.10

  • 濾胞性リンパ腫と多発性骨髄腫を合併し、VR-CAP療法が奏功した一例

    第120回 日本血液学会東北地方会  

      More details

    Event date: 2015.10

  • 肝障害を伴った骨髄線維症の1例

    第206回 日本内科学会東北地方会  

      More details

    Event date: 2015.10

  • 造血幹細胞移植後キメリズム解析の院内検査導入による移植医療への貢献

    第24回 日本組織適合性学会大会  

      More details

    Event date: 2015.9

  • モガムリズマブ併用自己末梢血幹細胞移植により長期寛解が得られた末梢性T細胞リンパ腫白血化の一例

    第28回 東北BMT研究会  

      More details

    Event date: 2015.7

  • モガムリズマブ併用自己末梢血幹細胞移植により長期寛解が得られている末梢性T細胞リンパ腫白血化の一例

    第62回 福島血液研究会  

      More details

    Event date: 2015.7

  • Membrane type1-matrix metalloproteinase (MT1-MMP)/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells

    The 79th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2015.4

  • 同種造血細胞移植において生着後輸血が予後に及ぼす影響

    第106回 日本輸血・細胞治療学会東北支部例会  

      More details

    Event date: 2015.3

  • 生着後輸血が同種造血幹細胞移植後の転帰に及ぼす影響

    第37回 日本造血細胞移植学会総会  

      More details

    Event date: 2015.3

  • 洞不全症候群を合併したCastleman病の1例

    第204回 日本内科学会東北地方会  

      More details

    Event date: 2015.2

  • 白血病化学療法後の真菌感染合併症の2例

    血液MEETING in 福島 2015  

      More details

    Event date: 2015.2

  • 膜型マトリックスメタロプロテアーゼ(MT1-MMP)がTNF-αによって誘導される凝固活性亢進および内皮細胞アポトーシスをコントロールする新たなメカニズムの解明

    平成26年度福島医学会表彰受賞 授与式・受賞記念講演会  

      More details

    Event date: 2015.1

  • 膜型マトリックスメタロプロテアーゼ(MT1-MMP)がTNF-αによって誘導される凝固活性亢進および内皮細胞アポトーシスをコントロールする新たなメカニズムの解明

    平成26年度福島医学会表彰受賞 授与式・受賞記念講演会  

      More details

    Event date: 2015

  • 肝障害を伴った骨髄線維症の1例

    第206回 日本内科学会東北地方会  

      More details

    Event date: 2015

  • 白血病化学療法後の真菌感染合併症の2例

    血液MEETING in 福島 2015  

      More details

    Event date: 2015

  • 生着後輸血が同種造血幹細胞移植後の転帰に及ぼす影響

    第37回 日本造血細胞移植学会総会  

      More details

    Event date: 2015

  • 濾胞性リンパ腫と多発性骨髄腫を合併し、VR-CAP療法が奏功した一例

    第120回 日本血液学会東北地方会  

      More details

    Event date: 2015

  • 洞不全症候群を合併したCastleman病の1例

    第204回 日本内科学会東北地方会  

      More details

    Event date: 2015

  • 同種造血細胞移植において生着後輸血が予後に及ぼす影響

    第106回 日本輸血・細胞治療学会東北支部例会  

      More details

    Event date: 2015

  • モガムリズマブ併用自己末梢血幹細胞移植により長期寛解が得られている末梢性T細胞リンパ腫白血化の一例

    第62回 福島血液研究会  

      More details

    Event date: 2015

  • Transfusions after engraftment associate with non-relapse mortality in the setting of allo-HSCT

    第77回 日本血液学会学術集会  

      More details

    Event date: 2015

  • Transfusions after engraftment associate with non-relapse mortality in the setting of allo-HSCT

    Transfusions after engraftment associate with non-relapse mortality in the setting of allo-HSCT  

      More details

    Event date: 2015

  • Persistent CR of acute leukemic-phase CCR4+γδ PTCL-NOS by auto-PBSCT with mogamulizumab

    第77回 日本血液学会学術集会  

      More details

    Event date: 2015

  • Persistent CR of acute leukemic-phase CCR4+γδ PTCL-NOS by auto-PBSCT with mogamulizumab

    Persistent CR of acute leukemic-phase CCR4+γδ PTCL-NOS by auto-PBSCT with mogamulizumab  

      More details

    Event date: 2015

  • Membrane type1-matrix metalloproteinase (MT1-MMP)/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells

    第79回 日本循環器学会学術集会  

      More details

    Event date: 2015

  • Membrane type1-matrix metalloproteinase (MT1-MMP)/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells

    The 79th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2015

  • IgG4関連疾患とB細胞性EBVリンパ増殖異常症を合併した症例

    第31回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2015

  • Dysregulation of let-7/HMGA2 axis can be a target of histone deacetylase inhibitor in MPNs

    第77回 日本血液学会学術集会  

      More details

    Event date: 2015

  • Dysregulation of let-7/HMGA2 axis can be a target of histone deacetylase inhibitor in MPNs

    Dysregulation of let-7/HMGA2 axis can be a target of histone deacetylase inhibitor in MPNs  

      More details

    Event date: 2015

  • Autocrine and paracrine regulatory mechanisms of growth arrest-specific Gene 6 contribute to disease progression of multiple myeloma

    57th American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2015

  • Autocrine and paracrine regulatory mechanisms of growth arrest-specific Gene 6 contribute to disease progression of multiple myeloma

    57th American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2015

  • Autocrine and paracrine regulation by Gas 6 contributes to multiple myeloma disease progression

    Autocrine and paracrine regulation by Gas 6 contributes to multiple myeloma disease progression  

      More details

    Event date: 2015

  • Autocrine and paracrine regulation by Gas 6 contributes to multiple myeloma disease progression

    第77回 日本血液学会学術集会  

      More details

    Event date: 2015

  • Dysregulation of the let-7/HMGA2 axis with methylation of p16 promoter as a possible target of histone deacetylase inhibitor in myeloproliferative neoplasms

    2014 American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2014.12

  • Impact of red blood cell and platelet transfusions at early after engraftment on outcome of allogeneic hematopoietic stem cell transplantation

    2014 American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2014.12

  • 同種造血幹細胞移植後における生着後の輸血と転帰の相関

    第42回 福島造血幹細胞移植治療研究会  

      More details

    Event date: 2014.11

  • 治療抵抗性CD20陰性DLBCLの1例

    第30回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2014.11

  • Correlation of HMGA2 mRNA and let-7 micro RNAs with Methylation of p16 in MPNs

      More details

    Event date: 2014.11

  • 自家末梢血幹細胞移植後再発を疑われた末梢性T細胞リンパ腫

    第13回 福島・新潟・山形 血液スライドカンファレンス  

      More details

    Event date: 2014.10

  • ホジキンリンパ腫に続発したγδ T 細胞性リンパ腫/白血病の1 例

    第118回 日本血液学会東北地方会  

      More details

    Event date: 2014.9

  • RhD陰性血輸血を行い救命しえた同種骨髄移植後の自己免疫性溶血貧血

    第27回 東北BMT研究会  

      More details

    Event date: 2014.7

  • 胸膜孤在性線維性腫瘍に伴って発症した自己免疫性溶血性貧血

    第61回 福島血液研究会  

      More details

    Event date: 2014.7

  • ホジキンリンパ腫の治療後に顕在化したγδTCR陽性末梢性T細胞性リンパ腫(PTCL)

    第54回 日本リンパ網内系学会総会  

      More details

    Event date: 2014.6

  • The role of deregulated HMGA2 expression due to repressed let-7 micro RNA in myeloproliferative neoplasm (MPNs)

    The 5th JSH International Symposium 2014  

      More details

    Event date: 2014.5

  • ホジキンリンパ腫の治療後に顕在化したγδTCR陽性T細胞性リンパ腫の一例

    第20回 血器腫瘍研究会  

      More details

    Event date: 2014.4

  • Auto PBSCT for POEMS syndrome with pulmonary hypertension

      More details

    Event date: 2014.3

  • EBV感染を伴わないCD8+CD56+節外性リンパ腫の2例

    第117回 日本血液学会東北地方会  

      More details

    Event date: 2014.2

  • 抗インフルエンザウイルス薬(ペラミビル)投与後に発症した重篤な血小板減少症の1例

    第201回 日本内科学会東北地方会  

      More details

    Event date: 2014.2

  • Auto PBSCT for POEMS syndrome with pulmonary hypertension

    Auto PBSCT for POEMS syndrome with pulmonary hypertension  

      More details

    Event date: 2014

  • 自家末梢血幹細胞移植後再発を疑われた末梢性T細胞リンパ腫

    第13回 福島・新潟・山形 血液スライドカンファレンス  

      More details

    Event date: 2014

  • 胸膜孤在性線維性腫瘍に伴って発症した自己免疫性溶血性貧血

    第61回 福島血液研究会  

      More details

    Event date: 2014

  • 治療抵抗性CD20陰性DLBCLの1例

    第30回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2014

  • 抗インフルエンザウイルス薬(ペラミビル)投与後に発症した重篤な血小板減少症の1例

    第201回 日本内科学会東北地方会  

      More details

    Event date: 2014

  • 同種造血幹細胞移植後における生着後の輸血と転帰の相関

    第42回 福島造血幹細胞移植治療研究会  

      More details

    Event date: 2014

  • ホジキンリンパ腫の治療後に顕在化したγδTCR陽性末梢性T細胞性リンパ腫(PTCL)

    第54回 日本リンパ網内系学会総会  

      More details

    Event date: 2014

  • ホジキンリンパ腫の治療後に顕在化したγδTCR陽性T細胞性リンパ腫の一例

    第20回 血器腫瘍研究会  

      More details

    Event date: 2014

  • ホジキンリンパ腫に続発したγδ T 細胞性リンパ腫/白血病の1 例

    第118回 日本血液学会東北地方会  

      More details

    Event date: 2014

  • The role of deregulated HMGA2 expression due to repressed let-7 micro RNA in myeloproliferative neoplasm (MPNs)

    The 5th JSH International Symposium 2014  

      More details

    Event date: 2014

  • The role of deregulated HMGA2 expression due to repressed let-7 micro RNA in myeloproliferative neoplasm (MPNs)

    The 5th JSH International Symposium 2014  

      More details

    Event date: 2014

  • RhD陰性血輸血を行い救命しえた同種骨髄移植後の自己免疫性溶血貧血

    第27回 東北BMT研究会  

      More details

    Event date: 2014

  • POEMS症候群に対してauto PBSCTを施行した一例

    第36回 日本造血細胞移植学会総会  

      More details

    Event date: 2014

  • Impact of red blood cell and platelet transfusions at early after engraftment on outcome of allogeneic hematopoietic stem cell transplantation

    2014 American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2014

  • Impact of red blood cell and platelet transfusions at early after engraftment on outcome of allogeneic hematopoietic stem cell transplantation

    2014 American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2014

  • EBV感染を伴わないCD8<sup>+</sup>CD56<sup>+</sup>節外性リンパ腫の2例

    第117回 日本血液学会東北地方会  

      More details

    Event date: 2014

  • Dysregulation of the let-7/HMGA2 axis with methylation of p16 promoter as a possible target of histone deacetylase inhibitor in myeloproliferative neoplasms

    2014 American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2014

  • Dysregulation of the let-7/HMGA2 axis with methylation of p16 promoter as a possible target of histone deacetylase inhibitor in myeloproliferative neoplasms

    2014 American Society of Hematology (ASH) Annual Meeting and Exposition  

      More details

    Event date: 2014

  • Correlation of HMGA2 mRNA and let-7 micro RNAs with Methylation of p16 in MPNs

    Correlation of HMGA2 mRNA and let-7 micro RNAs with Methylation of p16 in MPNs  

      More details

    Event date: 2014

  • Correlation of HMGA2 mRNA and let-7 micro RNAs with Methylation of p16 in MPNs

    第76回 日本血液学会学術集会  

      More details

    Event date: 2014

  • CD8+CD568+EBV8-節外性リンパ腫の2例

    第29回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2013.11

  • Expression of NECDIN in acute myeloid leukemia (AML)

      More details

    Event date: 2013.10

  • ダサチニブにより良好な治療反応が得られたµ-BCR/ABL陽性慢性骨髄性白血病 (CML)

    第116回 日本血液学会東北地方会  

      More details

    Event date: 2013.8

  • ラスブリカーゼにより透析離脱後、寛解に導入し得たバーキットリンパ腫/白血病の一例

    第60回 福島血液研究会  

      More details

    Event date: 2013.7

  • Breast tumor as a presentation of extranodal T-cell lymphoblastic lymphoma-clinical and pathological analysis

    The 4th JSH International Symposium 2013 in Ehime  

      More details

    Event date: 2013.5

  • Double Ph染色体にmicro BCR-ABLを伴ったCMLの一例

    第19回 造血器腫瘍研究会  

      More details

    Event date: 2013.4

  • short tandem repeat増幅(STR-PCR)法による造血幹細胞移植後のキメリズム解析

    第102回 日本輸血・細胞治療学会 東北支部例会  

      More details

    Event date: 2013.3

  • 稀な組織型を呈した乳房リンパ腫の1例

    第115回 日本血液学会東北地方会  

      More details

    Event date: 2013.2

  • 良性NK細胞増殖疾患と考えられた1例

    第198回 日本内科学会東北地方会  

      More details

    Event date: 2013.2

  • Breast tumor as a presentation of extranodal T-cell lymphoblastic lymphoma-clinical and pathological analysis

    The 4th JSH International Symposium 2013 in Ehime  

      More details

    Event date: 2013

  • 良性NK細胞増殖疾患と考えられた1例

    第198回 日本内科学会東北地方会  

      More details

    Event date: 2013

  • 稀な組織型を呈した乳房リンパ腫の1例

    第115回 日本血液学会東北地方会  

      More details

    Event date: 2013

  • ラスブリカーゼにより透析離脱後、寛解に導入し得たバーキットリンパ腫/白血病の一例

    第60回 福島血液研究会  

      More details

    Event date: 2013

  • ダサチニブにより良好な治療反応が得られたμ-<i>BCR/ABL</i>陽性慢性骨髄性白血病 (CML)

    第116回 日本血液学会東北地方会  

      More details

    Event date: 2013

  • short tandem repeat増幅(STR-PCR)法による造血幹細胞移植後のキメリズム解析

    第102回 日本輸血・細胞治療学会 東北支部例会  

      More details

    Event date: 2013

  • Expression of NECDIN in acute myeloid leukemia (AML)

    第75回 日本血液学会学術集会  

      More details

    Event date: 2013

  • Expression of NECDIN in acute myeloid leukemia (AML)

    Expression of NECDIN in acute myeloid leukemia (AML)  

      More details

    Event date: 2013

  • Double Ph染色体にmicro BCR-ABLを伴ったCMLの一例

    第19回 造血器腫瘍研究会  

      More details

    Event date: 2013

  • CD8<sup>+</sup>CD568<sup>+</sup>EBV8<sup>-</sup>節外性リンパ腫の2例

    第29回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2013

  • Breast tumor as a presentation of extranodal T-cell lymphoblastic lymphoma-clinical and pathological analysis

    The 4th JSH International Symposium 2013 in Ehime  

      More details

    Event date: 2013

  • 自己免疫性リンパ増殖症候群に続発したキャスルマン病

    第28回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2012.11

  • 皮疹や感染を繰り返しながら極めて緩徐な経過を辿っている急性骨髄性白血病(AML)

    第11回 福島・新潟・山形血液サイドカンファレンス  

      More details

    Event date: 2012.10

  • 極めて緩徐な経過を辿っている急性骨髄性白血病(AML)くすぶり型AML

    第114回 日本血液学会東北地方会  

      More details

    Event date: 2012.9

  • 鉄キレート療法が有効であった再生不良性貧血の2症例

    第197回 日本内科学会東北地方会  

      More details

    Event date: 2012.9

  • 同種骨髄移植後における制御性T細胞の動態

    第25回 東北BMT研究会  

      More details

    Event date: 2012.7

  • デフェラシロクスを用いた鉄キレート療法が有効であった再生不良性貧血の2症例

    第59回 福島血液研究会  

      More details

    Event date: 2012.7

  • IRF4に関連した染色体転座T(1;6)を有した慢性リンパ性白血病の一例

    第52回 日本リンパ網内系学会総会  

      More details

    Event date: 2012.6

  • 多発性骨髄腫ってどんな病気?

    日本骨髄腫患者の会 第1回福島ブロック会  

      More details

    Event date: 2012.5

  • 30年以上経過した後に再燃した鼻腔内リンパ腫の一例

    第18回 造血器腫瘍研究会  

      More details

    Event date: 2012.4

  • 脊椎原発EBV関連リンパ腫の一例

    第113回 日本血液学会東北地方会  

      More details

    Event date: 2012.2

  • 緩徐に経過したIgH/MYC陽性悪性リンパ腫の1例

    第195回 日本内科学会東北地方会  

      More details

    Event date: 2012.2

  • 健診にて便潜血陽性で発見され、DLBCLとの鑑別が困難であったlow risk Burkitt lymphomaの1例

    第27回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2011.11

  • 染色体転座t(1;6)を有した慢性リンパ性白血病の一例

    第112回 日本血液学会東北地方会  

      More details

    Event date: 2011.9

  • Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) is a Novel Multifunctional Modifier for Vascular Responses

    The 75th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2011.8

  • Preventive effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by epicardial coronary artery endothelial denudation

    The 75th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2011.8

  • Integral Role of MT1-MMP in Thrombin-triggered RhoA and Rac1 Activation and Their Downstream Events in Endothelial Cells

    The 75th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2011.8

  • Crucial roles of MT1-MMP on TNF-α-induced signaling pathways of endothelial cell apoptosis and haemostasis

    The 75th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2011.8

  • 自家末梢血幹細胞移植後にサイトメガロウイルス感染が原因と考えられた血球貪食症候群の2 例

    第33回 日本造血細胞移植学会総会  

      More details

    Event date: 2011.3

  • 右心房腫瘤で再発したびまん性大細胞性B細胞性リンパ腫の一例

    第111回 日本血液学会東北地方会  

      More details

    Event date: 2011.2

  • 寛解中に濾胞性リンパ腫を発症した急性骨髄性白血病(M2)の症例

    第193回 日本内科学会東北地方会  

      More details

    Event date: 2011.2

  • MT1-MMP controls Akt-dependent Fox01 activation in TNF-α-induced signaling pathways of endothelial cell apoptosis and haemostasis

    Scientific Sessions of American Heart Association 2010  

      More details

    Event date: 2010.11

  • MT1-MMP forms a complex with Gi and regulates eNOS expression at posttranscriptional mechanism in oxidized LDL stimulated-endothelial cells

    Scientific Sessions of American Heart Association 2010  

      More details

    Event date: 2010.11

  • 心不全徴候で再発したDLBCLの1例

    第26回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2010.11

  • 急性骨髄性白血病の完全寛解中に濾胞性リンパ腫を発症した1症例

    第26回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2010.11

  • 睡眠時無呼吸症候群(SAS)患者における肝機能及び内皮機能障害に関する検討

    Japan Digestive Disease Week (JDDW) 2010  

      More details

    Event date: 2010.10

  • Analysis of autologous PBSCT in four patients with cardiac amyloidosis

      More details

    Event date: 2010.9

  • A PNH patient complained of MDS and developed AML

      More details

    Event date: 2010.9

  • Crucial role of MT1-MMP in haemostasis and endothelial apoptosis in TNF-α-stimulated ECs

      More details

    Event date: 2010.9

  • Two paroxysmal nocturnal hemoglobinuria patients reached hematological and clonal remission

      More details

    Event date: 2010.9

  • ボルテゾミブが奏効した孤発性骨形質細胞腫の一例

    第110回 日本血液学会東北地方会  

      More details

    Event date: 2010.9

  • 血管内皮細胞での凝固亢進および線溶不全の分子機構における膜型マトリックスメタロプロテアーゼ(MT1-MMP)の役割

    第48回 東北止血・血栓研究会  

      More details

    Event date: 2010.9

  • LOX-1 cooperates with renin-angiotensin system in monocyte adhesion-induced redox-sensitive and Ca2+ signaling pathways in endothelial cells

    Congress of the European Society of Cardiology 2010  

      More details

    Event date: 2010.8

  • Membrane Type I Matrix Metalloproteinase (MT1-MMP) mediates thrombin-induced RhoA/Rac1 activation and their downstream signaling in endothelial cells

    Congress of the European Society of Cardiology 2010  

      More details

    Event date: 2010.8

  • Preventive effects of pravastatin on thrombin-triggered vascular responses mediated via Akt/eNOS and RhoA/Rac1 signaling pathways in vivo in rats

      More details

    Event date: 2010.7

  • Membrane Type I Matrix Metalloproteinase (MT1-MMP) mediates thrombin-induced RhoA/Rac1 activation and their downstream events in endothelial cells

      More details

    Event date: 2010.7

  • Bortezomibが奏効したsolitary plasmacytomaの一例

    第57回 福島血液研究会  

      More details

    Event date: 2010.6

  • 妊娠健診で見つかった慢性骨髄性白血病の1例

    第191回 日本内科学会東北地方会  

      More details

    Event date: 2010.6

  • LOX-1 cooperates with renin-angiotensin system (RAS) in monocyte adhesion-induced redox-sensitive and Ca2+ signaling pathways in endothelial cells (ECs)

    20th World Congress of the International Society for Heart Research (ISHR)  

      More details

    Event date: 2010.5

  • Pivotal role of receptor for advanced glycation end products (RAGE) in hyperlipidemia-dependent atherosclerosis and molecular regulation

    20th World Congress of the International Society for Heart Research (ISHR)  

      More details

    Event date: 2010.5

  • M蛋白血症を示した多発性骨髄腫とリンパ形質細胞性リンパ腫の二例

    第17回 造血器腫瘍研究会  

      More details

    Event date: 2010.4

  • 血管内皮細胞機能障害と活性酸素種産生に対するプラバスタチン静脈内投与の効果とその機序

    第13回 福島動脈硬化Forum  

      More details

    Event date: 2010.4

  • LOX-1 mediates renin-angiotensin system (RAS)-dependent redox-sensitive and Ca2+ signaling pathways induced in endothelial cells by monocyte adhesion

    The 74th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2010.3

  • Akt cooperates with membrane type 1-matorix metalloproteinase (MT1-MMP) in TNF-α-induced signaling pathways in vascular responses

    The 74th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2010.3

  • Pivotal role of receptor for advanced glycation end products (RAGE) in hyperlipidemia-dependent atherosclerosis and molecular regulation

    The 74th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2010.3

  • MT1-MMP forms a complex with LOX-1 and plays a crucial role in oxidized LDL-induced endothelial dysfunction via RhoA/Rac1 activation

    The 74th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2010.3

  • Crucial role of MT1-MMP in RhoA activation and Ca2+ signaling in thrombin-stimulated endothelial cells

    The 74th Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2010.3

  • HLA抗体陽性患者に造血幹細胞移植を行った自験例3例

    第109回 日本血液学会東北地方会  

      More details

    Event date: 2010.2

  • 多発性骨髄腫と診断し得たIgM型M蛋白血症の1例

    第190回 日本内科学会東北地方会  

      More details

    Event date: 2010.2

  • Auto-PBSCT後にBD療法を施行し、良好な経過を得たアミロイドーシス合併例

    第2回 福島県骨髄腫セミナー  

      More details

    Event date: 2010.2

  • IgM型多発性骨髄腫の一例

    第25回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2009.11

  • Akt cooperates with membrane type 1-matrix metalloproteinase (MT1-MMP) in TNF-α-induced signaling pathways of endothelial dysfunction and haemostasis

    Scientific Sessions of American Heart Association 2009  

      More details

    Event date: 2009.11

  • LOX-1 mediates renin-angiotensin system (RAS)-dependent redox-sensitive and Ca2+ signaling pathways induced in endothelial cells by monocyte adhesion

    Scientific Sessions of American Heart Association 2009  

      More details

    Event date: 2009.11

  • Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+ signaling pathways in ECs

      More details

    Event date: 2009.10

  • Autologous peripheral blood stem cell transplantation for AL amyloidosis

      More details

    Event date: 2009.10

  • TS-1/CPT-11併用療法が奏効した胃原発形質細胞腫の一例

    第51回 日本消化器病学会大会  

      More details

    Event date: 2009.10

  • 内皮細胞への単球接着系でのレドックス、Akt/eNOSおよびカルシウムシグナル伝達における酸化LDL受容体LOX-1の役割

    第47回 東北止血・血栓研究会  

      More details

    Event date: 2009.9

  • 当科における中心静脈カテーテル関連血流感染の現状

    第108回 日本血液学会東北地方会  

      More details

    Event date: 2009.9

  • Crucial role of LOX-1 in monocyte adhesion-triggered NADPH oxidase-dependent, Akt/eNOS and Ca2+ signaling pathways in endothelial cells

    Congress of the European Society of Cardiology 2009  

      More details

    Event date: 2009.8

  • Membrane type matrix metalloproteinase-1 (MT1-MMP) is a cell surface modifier of RhoA/Rac1-mediated signaling pathways and forms a complex with LOX-1 in oxidized LDL-induced endothelial dysfunction

    Congress of the European Society of Cardiology 2009  

      More details

    Event date: 2009.8

  • 輸血後に複数の同種抗体を産生し遅発性溶血を呈した自己免疫性溶血性貧血の一例

    第56回 福島血液研究会  

      More details

    Event date: 2009.7

  • Integral role of receptor for advanced glycation end products (RAGE) in non-diabetic atherosclerosis

      More details

    Event date: 2009.7

  • Crucial role of unprocessed RhoA and Rac1 in progression of atherosclerosis in Watanabe heritable hyperlipidemic (WHHL) Rabbits

      More details

    Event date: 2009.7

  • Crucial role of RhoA and Ca2+ signaling in the synthesis TF and PAI-1 in thrombin-stimulated endothelial cells

      More details

    Event date: 2009.7

  • 輸血後に複数の同種抗体を産生し遅発性溶血を呈した自己免疫性溶血性貧血の1例

    第188回 日本内科学会東北地方会  

      More details

    Event date: 2009.6

  • 血管内皮細胞機能不全における酸化LDL誘導RhoA・Rac1活性化とLOX-1/MT1-MMP系の役割

    第12回 福島動脈硬化Forum  

      More details

    Event date: 2009.4

  • Rapid improvement of impaired endothelium-dependent vasodilation and Rac1/NADPH oxidase-derived ROS generation in vivo by pravastatin

    The 73rd Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2009.3

  • Involvement of membrane type 1-matrix metalloproteinase (MT1-MMP) in advanced glycation end products (AGE)/RAGE-signaling pathway

    The 73rd Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2009.3

  • TF/PAI-1発現における低分子G蛋白RhoA活性化と細胞内Ca2+シグナルの役割

    第107回 日本血液学会東北地方会  

      More details

    Event date: 2009.2

  • 巨大平滑筋腫に発生したびまん性大細胞性B細胞性リンパ腫 (DLBCL) の1例

    第187回 日本内科学会東北地方会  

      More details

    Event date: 2009.2

  • LOX-1 mediates redox-sensitive, Akt/eNOS and Ca2+ signaling pathways induced in endothelial cells by monocyte adhesion

    International Society for Heart Research (ISHR) The 25th Annual Meeting of ISHR Japanese Section  

      More details

    Event date: 2008.12

  • 巨大平滑筋腫に発生したび慢性大細胞性B細胞性リンパ腫の1例

    第24回 悪性リンパ腫(M.L.)研究会  

      More details

    Event date: 2008.11

  • LOX-1を介する単球接着血管内皮細胞のレドックス, Akt/eNOS, Ca2+シグナル伝達系

    第31回 日本血栓止血学会学術集会  

      More details

    Event date: 2008.11

  • Receptor for advanced glycation end products (RAGE) plays an integral role in non-diabetic atherosclerosis and oxidized LDL stimulation

    Scientific Sessions of American Heart Association 2008  

      More details

    Event date: 2008.11

  • Therapeutic targeting RAGE/MT-1-MMP/Rac1 axis in redox-sensitive signaling pathway in diabetic vascular remodeling

    Scientific Sessions of American Heart Association 2008  

      More details

    Event date: 2008.11

  • 特発性血小板減少性紫斑病と間違われたMay-Hegglin異常の一例

    第46回 東北止血・血栓研究会  

      More details

    Event date: 2008.9

  • Unprocessed RhoA・Rac1の活性化メカニズムと動脈硬化進展における役割(ワークショップ)

    第3回 ウサギフォーラム ー医療に貢献する実験用ウサギの新しい展開-  

      More details

    Event date: 2008.7

  • 非糖尿病性動脈硬化病変におけるRAGE (Receptor for advanced glycation end products) の役割(ワークショップ)

    第3回 ウサギフォーラム ー医療に貢献する実験用ウサギの新しい展開-  

      More details

    Event date: 2008.7

  • 非糖尿病性動脈硬化病変におけるRAGE (Receptor for advanced glycation end products) の役割

    第40回 日本動脈硬化学会総会・学術集会  

      More details

    Event date: 2008.7

  • 内皮細胞への単球接着系でのレドックス系およびカルシウムシグナル伝達における酸化LDL受容体LOX-1の役割とその重要性

    第40回 日本動脈硬化学会総会・学術集会  

      More details

    Event date: 2008.7

  • 血管内皮細胞機能不全と活性酸素種産生に対するプラバスタチン静脈内投与の効果とその機序

    第40回 日本動脈硬化学会総会・学術集会  

      More details

    Event date: 2008.7

  • 非糖尿病性動脈硬化病変におけるRAGE (Receptor for advanced glycation end products) の役割

    第11回 福島動脈硬化Forum  

      More details

    Event date: 2008.4

  • Atorvastatin blocks an advanced glycation end products (AGE)/ receptor for AGE (RAGE) axis in diabetic vascular responses

    第72回 日本循環器学会学術集会  

      More details

    Event date: 2008.3

  • 酸化LDLによる血管内皮機能不全におけるRhoA/Rac1活性化とLOX-1・MT1-MMP系の役割

    第37回 日本心脈管作動物質学会  

      More details

    Event date: 2008.2

  • 非糖尿病性動脈硬化病変におけるRAGE (Receptor for advanced glycation end products) の役割

    第37回 日本心脈管作動物質学会  

      More details

    Event date: 2008.2

  • 酸化LDL刺激による血管内皮機能不全におけるRhoA、Rac1活性化とlectin like oxidized-LDL receptor-1 (LOX-1) の役割

    福島医学会 第410回 学術集会  

      More details

    Event date: 2007.10

  • 動脈硬化病変の進展におけるRAGE (Receptor for Advanced Glycation End Products) の役割

    第39回 日本動脈硬化学会総会・学術集会  

      More details

    Event date: 2007.7

  • 酸化LDLによる血管内皮機能不全におけるRhoA, Rac1の役割

    第10回 福島動脈硬化Forum  

      More details

    Event date: 2007.4

  • RhoA-dependent PAI-1 gene expression induced in endothelial cells by monocyte adhesion is mediated via geranylgeranyl transferase I and Ca2+ signaling

      More details

    Event date: 2007.3

  • Pravastatin rapidly prevents thrombin-induced vasoconstriction and NADPH oxidase-dependent ROS generation in vivo: implications for beneficial effect

      More details

    Event date: 2007.3

  • New insights into regulation of diabetic vascular remodeling by an MT1-MMP-RAGE axis

      More details

    Event date: 2007.3

  • Monocyte adhesion induces gene expression mediated via LOX-1-dependent signaling pathways in endothelial cells

      More details

    Event date: 2007.3

  • 内皮細胞(EC)への単球接着系でのレドックスおよびカルシウムシグナルにおける酸化LDL受容体LOX-1の役割

    第143回 日本循環器学会東北地方会  

      More details

    Event date: 2007.2

  • Essential role of rapid geranylgeranylation from unprocessed RhoA in RhoA activation and acute effect of intravenous administration of statin on RhoA-dependent eNOS downregulation

      More details

    Event date: 2006.12

  • Essential role of rapid geranylgeranylation from unprocessed RhoA in RhoA activation and increase in unprocessed RhoA in atherosclerosis

    The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society  

      More details

    Event date: 2006.3

▼display all

Awards

  • 公益財団法人 先進医薬研究振興財団(血液医学研究)

    2019.10  

     More details

    Country:Japan

  • 福島県立医科大学附属病院 治験実施者表彰

    2018.10  

     More details

    Country:Japan

  • MSD学術研究助成 2018(MSD株式会社)

    2018.10  

     More details

    Country:Japan

  • 一般研究賞

    2017.11  

     More details

    Country:Japan

  • 公益信託 白血病研究会基金 一般研究賞(公益信託 白血病研究会基金)

    2016.10  

     More details

    Country:Japan

Research Projects

  • GVHD 及び TMA の病態における Gas6 関連シグナルの役割を解明し、 Gas6 関連シグナルが GVHD 及び TMA における新たな治療戦 略候補やバイオマーカーとなりえることを明らかにする

    2017.11 - 2018.10

  • 移植片対宿主病(GVHD)の発症におけるGas6の役割

    2016.5 - 2017.3

  • 低分子G蛋白/Aktを介する血管内皮機能不全の治療法確立の基礎的・臨床的研究

    2009.4 - 2010.3

  • 血管内皮機能不全と活性酸素種に対するプラバスタチン静脈内投与の効果とその機序

    2008

  • 非ゲラニルゲラニル化低分子GTP結合蛋白質の動脈硬化における役割と動脈硬化予知に関する研究

    2006