論文 - 藤原 一男
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Anti-myelin Oligodendrocyte Glycoprotein Antibodies in a Patient with Recurrent Optic Neuritis Involving the Cerebral White Matter and Brainstem.
Adachi T, Yasui K, Takahashi T, Fujihara K, Watanabe Y, Nakashima K
Intern Med 55 ( 10 ) 1351 - 1354 2016年5月
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Genetic analysis of the aquaporin-4 gene for anti-AQP4 antibody-positive neuromyelitis optica in a Japanese population.
Ogasawara M, Meguro A, Sakai T, Mizuki N, Takahashi T, Fujihara K, Tsuneoka H, Shikishima K
Jpn J Ophthalmol 60 ( 3 ) 198 - 205 2016年5月
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Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord.
Oji S, Nicolussi EM, Kaufmann N, Zeka B, Schanda K, Fujihara K, Illes Z, Dahle C, Reindl M, Lassmann H, Bradl M
PLoS One 2016年3月
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Pregnancy outcomes in aquaporin-4-positive neuromyelitis optica spectrum disorder.
Nour MM, Nakashima I, Coutinho E, Woodhall M, Sousa F, Revis J, Takai Y, George J, Kitley J, Santos ME, Nour JM, Cheng F, Kuroda H, Misu T, Martins-da-Silva A, DeLuca GC, Vincent A, Palace J, Waters P, Fujihara K, Leite MI
Neurology 86 ( 1 ) 79 - 87 2016年1月
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Myelin injury without astrocytopathy in neuroinflammatory disorders with MOG antibodies.
Kaneko K, Sato DK, Nakashima I, Nishiyama S, Tanaka S, Marignier R, Hyun JW, Oliveira LM, Reindl M, Seifert-Held T, Sepulveda M, Siritho S, Waters PJ, Kurosawa K, Akaishi T, Kuroda H, Misu T, Prayoonwiwat N, Berger T, Saiz A, Kim HJ, Nomura K, Callegaro D, Fujihara K, Aoki M
J Neurol Neurosurg Psychiatry 2016年1月
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Placebo-controlled study in neuromyelitis optica-Ethical and design considerations
Cree BA, Bennett JL, Sheehan M, Cohen J, Hartung HP, Aktas O, Kim HJ, Paul F, Pittock S, Weinshenker B, Wingerchuk D, Fujihara K, Cutter G, Patra K, Flor A, Barron G, Madani S, Ratchford JN, Katz E
Mult Scledr 2016年
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MRI and retinal abnormalities in isolated optic neuritis with myelin-oligodendrocyte glycoprotein and aquaporin-4 antibodies
Akaishi T, Sato DK, Nakashima I, Takeshita T, Takahashi T, Doi H, Kurosawa K, Kaneko K, Kuroda H, Nishiyama S, Misu T, Nakazawa T, Fujihara K, Aoki M
Journal of neurology, neurosurgery, and psychiatry 2016年
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The clinical spectrum associated with myelin oligodendrocyte glycoprotein antibodies (anti-MOG-Ab) in Thai patients
Siritho S, Sato DK, Kaneko K, Fujihara K, Prayoonwiwat N
Mult Scler 2016年
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Efficacy of intravenous methylprednisolone pulse therapy in patients with multiple sclerosis and neuromyelitis optica
Yamasaki R, Matsushita T, Fukazawa T, Yokoyama K, Fujihara K, Ogino M, Yokota T, Miyamoto K, Niino M, Nomura K, Tomioka R, Tanaka M, Kawachi I, Ohashi T, Kaida KI, Matsui M, Nakatsuji Y, Ochi H, Fukaura H, Kanda T, Nagaishi A, Togo K, Mizusawa H, Murai H, Kira JI
Mult Scler 2016年
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Quotient of cerebrospinal fluid/serum immunoglobulin G as a predictive factor for non-responders to intravenous methylprednisolone therapy in patients with relapsing neuromyelitis optica spectrum disorder: implication for early institution of plasmapheresis.
Oji S, Tanaka S, Kojima M, Fukaura H, Mori M, Takahashi T, Fujihara K, Nomura K
Clin Exp Neuroimmunol 7 272 - 280 2016年
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The Binding Property of a Monoclonal Antibody Against the Extracellular Domains of Aquaporin-4 Directs Aquaporin-4 Toward Endocytosis.
Huang P, Takai Y, Kusano-Arai O, Ramadhanti J, Iwanari H, Miyauchi T, Sakihama T, Han JY, Aoki M, Hamakubo T, Fujihara K, Yasui M, Abe Y
Biochem Biophys Rep 7 77 - 83 2016年
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Complement-dependent and -independent aquaporin 4-antibody-mediated cytotoxicity in human astrocytes: pathogenetic implications in neuromyelitis optica.
Nishiyama S, Misu T, Nuriya M, Takano R, Takahashi T, Nakashima I, Yasui M, Itoyama Y, Aoki M, Fujihara K
Biochem Biophys Rep 7 45 - 51 2016年
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Experimental neuromyelitis optica induces a type I interferon signature in the spinal cord.
Oji S, Nicolussi E, Kaufmann N, Schanda K, Fujihara K, Illes Z, Reindl M, Lassmann H, Bradl M
PLoS ONE 11 ( 3 ) 2016年
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Lesion length of optic neuritis impacts visual prognosi in neuromyelitis optica.
Akaishi T, Ichiro Nakashima, Takeshita T, Mugikura S, Sato DK, Takahashi T, Nishiyama S, Kurosawa K, Misu T, Nakazawa T, Aoki M, Fujihara K
J Neuroimmunol 293 28 - 33 2016年
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Different etiologies and prognoses of optic neuritis in demyelinating diseases.
Akaishi T, Nakashima I, Takeshita T, Kaneko K, Mugikura S, Sato DK, Takahashi T, Nakazawa T, Aoki M, Fujihara K
J Neuroimmnol 299 152 - 157 2016年
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Serological markers associated with neuromyelitis optica spectrum disorders in South India.
Pandit L, Sato DK, Mustafa S, Takahashi T, D'Cunha A, Malli C, Sudhir A, Fujihara K
Ann Indian Acad Neurol 19 ( 4 ) 505 - 509 2016年
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Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications".
Passos G, Sato D, Becker J, Fujihara K
Mediators Inflamm Mediators Inflamm 2016年
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High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin-4 competing with the neuromyelitis optica autoantibody, NMO-IgG.
Miyazaki-Komine K, Takai Y, Huang P, Kusano-Arai O, Iwanari H, Misu T, Koda K, Mitomo K, Sakihama T, Toyama Y, Fujihara K, Hamakubo T, Yasui M, Abe Y
Br J Pharmacol. 173 103 - 114 2016年
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The Binding Property of a Monoclonal Antibody Against the Extracellular Domains of Aquaporin-4 Directs Aquaporin-4 Toward Endocytosis.
Huang P, Takai Y, Kusano-Arai O, Ramadhanti J, Iwanari H, Miyauchi T, Sakihama T, Han JY, Aoki M, Hamakubo T, Fujihara K, Yasui M, Abe Y
Biochem Biophys Rep 7 77 - 83 2016年
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免疫性神経疾患-病態解明と治療の最前線:NMOの発症機序
小川 諒, 藤原一男
医学のあゆみ 2015年