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Detection of four isomers of the human cytomegalovirus genome using nanopore long-read sequencing.
Nanamiya H, Tanaka D, Hiyama G, Isogai T, Watanabe S
Virus genes
60
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4
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377
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384
2024年8月（ ISSN:0920-8569
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Identification and clinical significance of somatic oncogenic mutations in epithelial ovarian cancer.
Watanabe T, Nanamiya H, Endo Y, Kojima M, Nomura S, Furukawa S, Soeda S, Tamura H, Ryufuku M, Tanaka D, Isogai T, Imai JI, Watanabe S, Fujimori K
Journal of ovarian research
14
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129
2021年10月
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Clinical relevance of oncogenic driver mutations identified in endometrial carcinoma.
Watanabe T, Nanamiya H, Kojima M, Nomura S, Furukawa S, Soeda S, Tanaka D, Isogai T, Imai JI, Watanabe S, Fujimori K
Translational oncology
14
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3
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101010
2021年3月（ ISSN:1936-5233
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Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden.
Muto S, Ozaki Y, Yamaguchi H, Mine H, Takagi H, Watanabe M, Inoue T, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H
Oncology letters
21
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3
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203
2021年3月（ ISSN:1792-1074
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Clinical implication of oncogenic somatic mutations in early-stage cervical cancer with radical hysterectomy.
Watanabe T, Nanamiya H, Kojima M, Nomura S, Furukawa S, Soeda S, Tanaka D, Isogai T, Imai JI, Watanabe S, Fujimori K
Scientific reports
10
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1
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18734
2020年10月
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Non-pathogenic Escherichia coli acquires virulence by mutating a growth-essential LPS transporter.
Kaito C, Yoshikai H, Wakamatsu A, Miyashita A, Matsumoto Y, Fujiyuki T, Kato M, Ogura Y, Hayashi T, Isogai T, Sekimizu K
PLoS pathogens
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e1008469
2020年4月（ ISSN:1553-7366
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Tumor mutation burden and immunological, genomic, and clinicopathological factors as biomarkers for checkpoint inhibitor treatment of patients with non-small-cell lung cancer.
Ozaki Y, Muto S, Takagi H, Watanabe M, Inoue T, Fukuhara M, Yamaura T, Okabe N, Matsumura Y, Hasegawa T, Ohsugi J, Hoshino M, Shio Y, Tanaka D, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H
Cancer immunology, immunotherapy : CII
69
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127
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134
2020年1月（ ISSN:0340-7004
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【日本バイオの技と粋(6)】 日本の完全長cDNAプロジェクトの話
菅野 純夫, 太田 紀夫, 磯貝 隆夫
バイオサイエンスとインダストリー
76
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320
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327
2018年7月（ ISSN:0914-8981
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Prognostic Impact of Tumor Mutation Burden in Patients With Completely Resected Non-Small Cell Lung Cancer: Brief Report.
Owada-Ozaki Y, Muto S, Takagi H, Inoue T, Watanabe Y, Fukuhara M, Yamaura T, Okabe N, Matsumura Y, Hasegawa T, Ohsugi J, Hoshino M, Shio Y, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer
2018年4月（ ISSN:1556-0864
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Exploring the possibility of new biomarkers of immune checkpoint inhibitors for non-small cell lung cancer (NSCLC)
Owada Y., Inoue T., Watanabe Y., Fukuhara M., Yamaura T., Muto S., Matsumura Y., Hasegawa T., Tanaka D., Kanno R., Ito E., Nanamiya H., Imai J., Isogai T., Watanabe S., Suzuki H.
Japanese Journal of Cancer and Chemotherapy
44
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763
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766
2017年9月（ ISSN:03850684
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[Exploring the Possibility of New Biomarkers of Immune Checkpoint Inhibitors for Non-Small Cell Lung Cancer (NSCLC)].
Owada Y, Inoue T, Watanabe Y, Fukuhara M, Yamaura T, Muto S, Matsumura Y, Hasegawa T, Tanaka D, Kanno R, Ito E, Nanamiya H, Imai J, Isogai T, Watanabe S, Suzuki H
Gan to kagaku ryoho. Cancer & chemotherapy
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763
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766
2017年9月（ ISSN:0385-0684
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非小細胞肺癌における免疫チェックポイント阻害薬の新たなバイオマーカー抽出の可能性
大和田 有紀, 井上 卓哉, 渡邊 譲, 福原 光朗, 山浦 匠, 武藤 哲史, 松村 勇輝, 長谷川 剛生, 田中 大輔, 菅野 亮, 伊藤 恵美, 七宮 英晃, 今井 順一, 磯貝 隆夫, 渡辺 慎哉, 鈴木 弘行
癌と化学療法
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763
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766
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Identification of a long non-coding RNA as a novel biomarker and potential therapeutic target for metastatic prostate cancer
Crea F., Watahiki A., Quagliata L., Xue H., Pikor L., Parolia A., Wang Y., Lin D., Lam W., Farrar W., Isogai T., Morant R., Castori-Eppenberger S., Chi K., Wang Y., Helgason C.
Oncotarget
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764
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774
2014年1月
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Genome-wide determination of RNA stability reveals hundreds of short-lived non-coding transcripts in mammals.
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Genome Res.
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947
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Identification and Characterization of Novel Genotoxic Stress-inducible Nuclear Long Noncoding RNAs in Mammalian Cells.
Rena Mizutani, Ai Wakamatsu, Noriyuki Tanaka, Hiroshi Yoshida, Naobumi Tochigi, Yoshio Suzuki, Tadahiro Oonishi, Hidenori Tani, Keiko Tano, Kenichi Ijiri, Takao Isogai, Nobuyoshi Akimitsu
PLoS ONE,
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2012年4月
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HGPD: Human Gene and Protein Database, 2012 update
Yukio Maruyam, Yoshifumi Kawamura, Tetsuo Nishikawa, Takao Isogai, Nobuo Nomura, Naoki Goshima
Nucleic Acids Res.
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Statistical analysis of features associated with protein expression/solubility in an in vivo Escherichia coli expression system and a wheat germ cell-free expression system.
Hirose, S., Kawamura, Y., Yokota, K., Kuroita, T., Natsume, T., Komiya, K., Tsutsumi, T., Suwa, Y., Isogai, T., Goshima, N., Noguchi, T.
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Alternative splicing of genes during neuronal differentiation of NT2 pluripotential human embryonal carcinoma cells
Ai Wakamatsu, Jun-ichi Imai, Shinya Watanabe, Takao Isogai
FEBS Letters,
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4041
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4047
2010年
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Comparative Analysis of Human Src-family Kinase Substrate Specificity
Takeda, Hiroyuki; Kawamura, Yoshifumi; Miura, Aya; Mori, Masatoshi; Wakamatsu, Ai; Yamamoto, Jun-ichi; Isogai, Takao; Matsumoto, Masaki; Nakayama, Keiichi; Natsume, Tohru; Nomura, Nobuo; Goshima, Naoki
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Development of Novel Synthetic Hydrophilic Resin for Drug-Protein Interaction Analysis
Akito Tanaka & Takao Isogai
Frontiers in Drug Design & Discovery
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41
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66
2010年
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Identification and Functional Analyses of 11,769 Full-length Human cDNAs Focused on Alternative Splicing
Ai Wakamatsu, Kouichi Kimura, Jun-ichi Yamamoto, Tetsuo Nishikawa, Nobuo Nomura, Sumio Sugano, Takao Isogai
DNA Res.
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Human Gene and Protein Database (HGPD): a novel database presenting a large quantity of experiment-based results in human proteomics
Yukio Maruyama, Ai Wakamatsu, Yoshifumi Kawamura, Kouichi Kimura, Jun-ichi Yamamoto, Tetsuo Nishikawa, Yasutomo Kisu, Sumio Sugano, Naoki Goshima, Takao Isogai, Nobuo Nomura
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Human protein factory for converting the transcriptome into an in vitro–expressed proteome
Naoki Goshima, Yoshifumi Kawamura, Akiko Fukumoto, Aya Miura, Reiko Honma, Ryohei Satoh, Ai Wakamatsu, Jun-ichi Yamamoto, Kouichi Kimura, Tetsuo Nishikawa, Taichi Andoh, Yuki Iida, Kumiko Ishikawa, Emi Ito, Naoko Kagawa, Chie Kaminaga, Kei-ichi Kanehori, Bunsei Kawakami, Kiyokazu Kenmochi, Rie Kimura, Miki Kobayashi, Toshihiro Kuroita, Hisashi Kuwayama, Yukio Maruyama, Kiyoshi Matsuo, Kazuyoshi Minami, Mariko Mitsubori, Masatoshi Mori, Riyo Morishita, Atsushi Murase, Akira Nishikawa, Shigemichi Nishikawa, Toshihiko Okamoto, Noriko Sakagami, Yutaka Sakamoto, Yukari Sasaki, Tomoe Seki, Saki Sono, Akio Sugiyama, Tsuyoshi Sumiya, Tomoko Takayama, Yukiko Takayama, Hiroyuki Takeda, Takushi Togashi, Kazuhide Yahata, Hiroko Yamada, Yuka Yanagisawa, Yaeta Endo, Fumio Imamoto, Yasutomo Kisu, Shigeo Tanaka, Takao Isogai, Jun-ichi Imai, Shinya Watanabe, Nobuo Nomura
Nature Methods
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1011
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The H-Invitational Database (H-InvDB), a comprehensive annotation resource for human genes and transcripts.
Genome Information Integration Project and H-Invitational 2 Consortium
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2008年
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Differential responses of normal human coronary artery endothelial cells against multiple cytokines comparatively assessed by gene expression profiles.
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Large-scale identification and characterization of alternative splicing variants of human gene transcripts using 56,419 completely sequenced and manually annotated full-length cDNAs.
Takeda J, Suzuki Y, Nakao M, Barrero RA, Koyanagi KO, Jin L, Motono C, Hata H, Isogai T, Nagai K, Otsuki T, Kuryshev V, Shionyu M, Yura K, Go M, Thierry-Mieg J, Thierry-Mieg D, Wiemann S, Nomura N, Sugano S, Gojobori T, Imanishi T.
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Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes
Kouichi Kimura, Ai Wakamatsu, Yutaka Suzuki, Toshio Ota, Tetsuo Nishikawa, Riu Yamashita, Jun-ichi Yamamoto, Mitsuo Sekine, Katsuki Tsuritani, Hiroyuki Wakaguri, Shizuko Ishii, Tomoyasu Sugiyama, Kaoru Saito, Yuko Isono, Ryotaro Irie, Norihiro Kushida, Takahiro Yoneyama, Rie Otsuka, Katsuhiro Kanda, Takahide Yokoi, Hiroshi Kondo, Masako Wagatsuma, Katsuji Murakawa, Shinichi Ishida, Tadashi Ishibashi, Asako Takahashi-Fujii, Tomoo Tanase, Keiichi Nagai, Hisashi Kikuchi, Kenta Nakai, Takao Isogai, Sumio Sugano
Genome Res.
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Signal Sequence and Keyword Trap in silico for Selection of Full-Length Human cDNAs Encoding Secretion or Membrane Proteins from Oligo-Capped cDNA Libraries
Tetsuji Otsuki, Toshio Ota, Tetsuo Nishikawa, Koji Hayashi, Yutaka Suzuki, Jun-ichi Yamamoto, Ai Wakamatsu, Kouichi Kimura, Katsuhiko Sakamoto, Naoto Hatano, Yuri Kawai, Shizuko Ishii, Kaoru Ssaito, Shin-ichi Kojima, Tomoyasu Sugiyama, Tetsuyoshi Ono, Kazunori Okano, Yoko Yoshikawa, Satoshi Aotsuka, Naokazu Sasaki, Atsushi Hattori, Koji Okumura, Keiichi Nagai, Sumio Sugano, Takao Isogai.
DNA Res.
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Integrative annotation of 21,037 human genes validated by full-length cDNA clones
Imanishi T, Itoh T, Suzuki Y, O'Donovan C, Fukuchi S, Koyanagi KO, Barrero RA, Tamura T, Yamaguchi-Kabata Y, Tanino M, Yura K, Miyazaki S, Ikeo K, Homma K, Kasprzyk A, Nishikawa T, Hirakawa M, Thierry-Mieg J, Thierry-Mieg D, Ashurst J, Jia L, Nakao M, Thomas MA, Mulder N, Karavidopoulou Y, Jin L, Kim S, Yasuda T, Lenhard B, Eveno E, Suzuki Y, Yamasaki C, Takeda J, Gough C, Hilton P, Fujii Y, Sakai H, Tanaka S, Amid C, Bellgard M, Bonaldo Md Mde F, Bono H, Bromberg SK, Brookes AJ, Bruford E, Carninci P, Chelala C, Couillault C, Souza SJ, Debily MA, Devignes MD, Dubchak I, Endo T, Estreicher A, Eyras E,----,Stodolsky M, Makalowski W, Go M, Nakai K, Takagi T, Kanehisa M, Sakaki Y, Quackenbush J, Okazaki Y, Hayashizaki Y, Hide W, Chakraborty R, Nishikawa K, Sugawara H, Tateno Y, Chen Z, Oishi M, Tonellato P, Apweiler R, Okubo K, Wagner L, Wiemann S, Strausberg RL, Isogai T, Auffray C, Nomura N, Gojobori T, Sugano S.
PLoS Biol.
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Complete sequencing and characterization of 21,243 full-length human cDNAs
Ota, T., Suzuki, Y., Nishikawa, T., Otsuki, T., Sugiyama, T., Irie, R., Wakamatsu, A., Hayashi, K., Sato, H., Nagai, K., Kimura, K., Makita, H., Sekine, M., Obayashi, M., Nishi, T., Shibahara, T., Tanaka, T., Ishii, S., Yamamoto, J., Saito, K., Kawai, Y., Isono, Y., Nakamura, Y., Nagahari, K., Murakami, K., Yasuda, T., Iwayanagi, T., Wagatsuma. M., -----, Nagase, T., Nomura, N., Kikuchi, H., Masuho, Y., Yamashita, R., Nakai, K., Yada, T., Nakamura, Y., Ohara, O., Isogai, T., Sugano, S.
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