論文 - 齋藤 元伸
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放射線治療による腫瘍細胞内cGAS-STING経路を介した食道扁平上皮癌微小環境の変化
中嶋正太郎, 三村耕作, 金田晃尚, 片方雅紀, 岡山洋和, 齋藤元伸, 佐瀬善一郎, 花山寛之, 多田武志, 門馬智之, 河野浩二
癌と化学療法 50 ( 10 ) 1099 - 1101 2023年10月（ ISSN:0385-0684 ）
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Down-regulation of stimulator of interferon genes (STING) expression and CD8(+) T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.
Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 6 ) 878 - 890 2023年8月（ ISSN:1436-3291 ）
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A Potential Biomarker of Dynamic Change in Peripheral CD45RA(-)CD27(+)CD127(+) Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma.
Sakuma M, Mimura K, Nakajima S, Kaneta A, Kikuchi T, Nirei A, Tada T, Hanayama H, Okayama H, Sakamoto W, Saito M, Momma T, Saze Z, Kono K
Cancers 15 ( 14 ) 3641 2023年7月（ ISSN:2072-6694 ）
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Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.
Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Dai J, Hung RJ, Chen K, Shu XO, Kim YT, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Song B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Funderburk KM, Li S, Zhang T, Breeze C, Wang Z, Blechter B, Bassig BA, Kim JH, Albanes D, Wong JYY, Shin MH, Chung LP, Yang Y, An SJ, Zheng H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Ho JCM, Kubo M, Daigo Y, Song M, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood DH, Kunitoh H, Patel H, Watanabe SI, Miyagi Y, Nakayama H, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Ohe Y, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Dai H, Machiela MJ, Su J, Kim YH, Oh IJ, Lee VHF, Chang GC, Tsai YH, Chen KY, Huang MS, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Chen KC, Gao YT, Qian B, Wu C, Lu D, Liu J, Schwartz AG, Houlston R, Spitz MR, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold S, Brennan P, McKay J, Field JK, Shete SS, Le Marchand L, Liu G, Andrew A, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Johansson M, Cox A, Taylor F, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Jeon HS, Jiang SS, Sung JS, Chen CH, Hsiao CF, Jung YJ, Guo H, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Zhu B, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Liu L, Kang CH, Wang WC, Xu J, Guan P, Tan W, Yu CJ, Yang G, Sihoe ADL, Chen Y, Choi YY, Kim JS, Yoon HI, Park IK, Xu P, He Q, Wang CL, Hung HH, Vermeulen RCH, Cheng I, Wu J, Lim WY, Tsai FY, Chan JKC, Li J, Chen H, Lin HC, Jin L, Liu J, Sawada N, Yamaji T, Wyatt K, Li SA, Ma H, Zhu M, Wang Z, Cheng S, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Jiang G, Fei K, Wu G, Chen CY, Chen CJ, Yang PC, Yu J, Stevens VL, Fraumeni JF Jr, Chatterjee N, Gorlova OY, Hsiung CA, Amos CI, Shen H, Chanock SJ, Rothman N, Kohno T, Lan Q
Nature communications 14 ( 1 ) 3043 2023年5月
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The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8(+) T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer.
Nakajima S, Kaneta A, Okayama H, Saito K, Kikuchi T, Endo E, Matsumoto T, Fukai S, Sakuma M, Sato T, Mimura K, Saito M, Saze Z, Sakamoto W, Onozawa H, Momma T, Kono K
Cancers 15 ( 10 ) 2826 2023年5月（ ISSN:2072-6694 ）
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Radiation-Induced Remodeling of the Tumor Microenvironment Through Tumor Cell-Intrinsic Expression of cGAS-STING in Esophageal Squamous Cell Carcinoma.
Nakajima S, Mimura K, Kaneta A, Saito K, Katagata M, Okayama H, Saito M, Saze Z, Watanabe Y, Hanayama H, Tada T, Sakamoto W, Momma T, Ohira H, Kono K
International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2023年3月（ ISSN:0360-3016 ）
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M2 tumor-associated macrophages resist to oxidative stress through heme oxygenase-1 in the colorectal cancer tumor microenvironment.
Ito M, Mimura K, Nakajima S, Okayama H, Saito K, Nakajima T, Kikuchi T, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Kono K
Cancer immunology, immunotherapy : CII 72 ( 7 ) 2233 - 2244 2023年3月（ ISSN:0340-7004 ）
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Clinical decisions by the molecular tumor board on comprehensive genomic profiling tests in Japan: A retrospective observational study.
Shirota H, Komine K, Takahashi M, Takahashi S, Miyauchi E, Niizuma H, Tada H, Shimada M, Niihori T, Aoki Y, Sugiyama I, Kawamura M, Yasuda J, Suzuki S, Iwaya T, Saito M, Saito T, Shibata H, Furukawa T, Ishioka C
Cancer medicine 12 ( 5 ) 6170 - 6181 2023年3月
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ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 3 ) 379 - 392 2023年2月（ ISSN:1436-3291 ）
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Clinical decisions by the molecular tumor board on comprehensive genomic profiling tests in Japan: A retrospective observational study.
Shirota H, Komine K, Takahashi M, Takahashi S, Miyauchi E, Niizuma H, Tada H, Shimada M, Niihori T, Aoki Y, Sugiyama I, Kawamura M, Yasuda J, Suzuki S, Iwaya T, Saito M, Saito T, Shibata H, Furukawa T, Ishioka C
Cancer medicine 12 ( 5 ) 6170 - 6181 2023年
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TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer.
Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, Fukai S, Endo E, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
Cancers 15 ( 20 ) 4943 2023年
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Short-term outcomes of neoadjuvant chemotherapy with capecitabine plus oxaliplatin for patients with locally advanced rectal cancer followed by total or tumor-specific mesorectal excision with or without lateral pelvic lymph node dissection.
Sakamoto W, Kanke Y, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Kono K
Fukushima journal of medical science 68 ( 2 ) 89 - 95 2022年8月（ ISSN:0016-2590 ）
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Laparoscopic total gastrectomy performed for juvenile polyposis of the stomach: A case report.
Ito M, Onozawa H, Saito M, Ami H, Ohki S, Koyama Y, Kono K
International journal of surgery case reports 97 107368 2022年8月
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Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer.
Kaneta A, Nakajima S, Okayama H, Matsumoto T, Saito K, Kikuchi T, Endo E, Ito M, Mimura K, Kanke Y, Saito M, Saze Z, Fujita S, Sakamoto W, Onozawa H, Momma T, Ohki S, Kono K
Cancer immunology, immunotherapy : CII 71 ( 11 ) 2765 - 2776 2022年4月（ ISSN:0340-7004 ）
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SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer.
Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K
British journal of cancer 126 ( 6 ) 917 - 926 2022年4月（ ISSN:0007-0920 ）
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A rare case of recurrent ovarian cancer with <i>TPM3-NTRK1</i> gene rearrangement: A case report.
Endo Y, Watanabe T, Saito M, Saito K, Suzuki R, Sano H, Natori Y, Sasaki E, Ueda M, Kamo N, Furukawa S, Soeda S, Kono K, Saji S, Fujimori K
Molecular and clinical oncology 16 ( 4 ) 90 2022年4月（ ISSN:2049-9450 ）
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Incidence of upper extremity deep vein thrombosis in the retrosternal reconstruction after esophagectomy.
Yamada L, Saito M, Suzuki H, Mochizuki S, Endo E, Kase K, Ito M, Nakano H, Yamauchi N, Matsumoto T, Kaneta A, Kanke Y, Onozawa H, Hanayama H, Okayama H, Fujita S, Sakamoto W, Watanabe Y, Hayase S, Saze Z, Momma T, Ohki S, Kono K
BMC surgery 22 ( 1 ) 91 2022年3月
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Immune escape mechanism behind resistance to anti-PD-1 therapy in gastrointestinal tract metastasis in malignant melanoma patients with multiple metastases.
Ito M, Mimura K, Nakajima S, Saito K, Min AKT, Okayama H, Saito M, Momma T, Saze Z, Ohtsuka M, Yamamoto T, Kono K
Cancer immunology, immunotherapy : CII 71 ( 9 ) 2293 - 2300 2022年1月（ ISSN:0340-7004 ）
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High Risk Stage II大腸癌におけるGlasgow Prognostic Scoreの意義と治療戦略
大木 進司, 岡山 洋和, 千田 峻, 坂本 渉, 藤田 正太郎, 齋藤 元伸, 門馬 智之, 佐瀬 善一郎, 河野 浩二
癌と化学療法 48 ( 13 ) 1770 - 1773 2021年12月（ ISSN:0385-0684 ）
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Immunotherapy Targeting Tumor-Associated Carbohydrate Antigens in Deficient Mismatch Repair Colorectal Cancer
Matsumoto T, Okayama H, Nakano H, Ito M, Nakajima S, Saito M, Saze Z, Momma T, Mimura K, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 10 ) 1275 - 1277 2021年10月（ ISSN:0385-0684 ）