論文 - 町田 豪
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Roles of MASP-1 and MASP-3 in the development of retinal degeneration in a murine model of dry age-related macular degeneration
Tomoko Omori, Takeshi Machida, Yumi Ishida, Tetstuju Sekiryu, and Hideharu Sekine
Frontiers in Immunology 16 1566018 2025年
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"Factor D" in "Alternative Pathway / Amplification Loop Basics"
Hideharu Sekine, Takeshi Machida, and Teizo Fujita
Immunological Reviews 313 15 - 24 2023年
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重症筋無力症の病態：補体の役割と活性化のメカニズム
町田豪, 関根英治
脳神経内科 98 809 - 815 2023年
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The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
Kohei Kusakari, Takeshi Machida, Yumi Ishida, Tomoko Omori, Toshiyuki Suzuki, Masayuki Sekimata, Ikuo Wada, Teizo Fujita, and Hideharu Sekine
Frontiers in Immunology 13 907023 2022年
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補体の多面性：自然免疫・獲得免疫と補体
町田豪, 関根英治
日本臨牀 80 1728 - 1734 2022年
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A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways
Mika Takasumi, Tomoko Omori, Takeshi Machida, Yumi Ishida, Manabu Hayashi, Toshiyuki Suzuki, Yoshimi Homma, Yuichi Endo, Minoru Takahashi, Hiromasa Ohira, Teizo Fujita, Hideharu Sekine
The FASEB Journal 34 6598 - 6612 2020年
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Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway
Manabu Hayashi, Takeshi Machida, Yumi Ishida, Yusuke Ogata, Tomoko Omori, Mika Takasumi, Yuichi Endo, Toshiyuki Suzuki, Masayuki Sekimata, Yoshimi Homma, Masahito Ikawa, Hiromasa Ohira, Teizo Fujita, and Hideharu Sekine
The Journal of Immunology 203 ( 6 ) 1411 - 1416 2019年（ ISSN:0022-1767 ）
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Response to Comment on “Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway”
Takeshi Machida, Manabu Hayashi, Teizo Fujita, and Hideharu Sekine
The Journal of Immunology 203 ( 12 ) 3091 - 3092 2019年
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Essential Roles for Mannose-Binding Lectin-Associated Serine Protease-1/3 in the Development of Lupus-Like Glomerulonephritis in MRL/lpr Mice
Takeshi Machida, Natsumi Sakamoto, Yumi Ishida, Minoru Takahashi, Teizo Fujita, and Hideharu Sekine
Frontiers in Immunology 9 1191 2018年
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Chloroplastic NADPH-dependent thioredoxin reductase from Chlorella vulgaris alleviates environmental stresses in yeast with 2-Cys peroxiredoxin
Takeshi Machida, Akiko Ishibashi, Ai Kirino, Jun-ichi Sato, Shinji Kawasaki, Youichi Niimura, Ken-ichi Honjoh, Takahisa Miyamoto
PLoS ONE 7 ( 9 ) e45988 2012年
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Expression pattern of a chloroplast NADPH-dependent thioredoxin reductase in Chlorella vulgaris and its interaction with 2-Cys peroxiredoxin.
Takeshi Machida, Eri Kato, Akiko Ishibashi, Jun-ichi Sato, Shinji Kawasaki, Youichi Niimura, Ken-ichi Honjoh, Takahisa Miyamoto
Bioscience, Biotechnology, and Biochemistry 73 695 - 701 2009年
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Isolation of cDNAs for hardening-induced genes from Chlorella vulgaris by suppression subtractive hybridization.
Takeshi Machida, Hisako Murase, Eri Kato, Ken-ichi Honjoh, Kiyoshi Matsumoto, Takahisa Miyamoto, Masayoshi Iio
Plant Science 175 238 - 246 2008年
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C5a stimulation induces caspase-1 activation and mature IL-1β production in human peripheral blood mononuclear cells
Yuya Fujita, Haruki Matsumoto, Kenji Inada, Michio Onizawa, Kenji Saito, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Tomoyuki Asano, Shuzo Sato, Takeshi Machida, Kiyoshi Migita
Immunological Medicine 47 68 - 75 2024年6月
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Complement activation products in tears of dry eye and meibomian gland dysfunction
Hiroki Maehara, Koki Norikawa, Keiichiro Tanaka, Yutaka Kato, Akihito Kasai, Ryo Mukai, Tomoko Omori, Takeshi Machida, Hideharu Sekine, Tetsuju Sekiryu
Scientific Reports 14 43 2024年1月
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Tear fluid and complement activation products in tears after ocular surgery.
Hiroki Maehara, Koki Norikawa, Keiichiro Tanaka, Yutaka Kato, Akihito Kasai, Tomoko Omori, Takeshi Machida, Hideharu Sekine, Tetsuju Sekiryu
BMC Ophthalmology 23 329 2023年7月
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Age-Related Maculopathy Susceptibility 2 and Complement Factor H Polymorphism and Intraocular Complement Activation in Neovascular Age-Related Macular Degeneration
Yutaka Kato, Yasuharu Oguchi, Tomoko Omori, Akihito Kasai, Masashi Ogasawara, Yukinori Sugano, Kanako Itagaki, Akira Ojima, Yumi Ishida, Takeshi Machida, Hideharu Sekine, Tetsuju Sekiryu
Ophthalmology Science 2 100167 2022年
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Increased CEACAM1 expression on peripheral blood neutrophils in patients with rheumatoid arthritis
Haruki Matsumoto, Yuya Fujita, Michio Onizawa, Kenji Saitoh, Yuya Sumichika, Shuhei Yoshida, Jumpei Temmoku, Naoki Matsuoka, Makiko Yashiro-Furuya, Tomoyuki Asano, Shuzo Sato, Eiji Suzuki, Takeshi Machida, Hiroshi Watanabe, Kiyoshi Migita
Frontiers in Immunology 13 978435 2022年
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Changes in complement activation products after anti-VEGF injection for choroidal neovascularization in age-related macular degeneration and pachychoroid disease
Keiichiro Tanaka, Yasuharu Oguchi, Tomoko Omori, Yumi Ishida, Hiroaki Shintake, Ryutaro Tomita, Akihito Kasai, Masashi Ogasawara, Yukinori Sugano, Kanako Itagaki, Akira Ojima, Takeshi Machida, Hideharu Sekine and Tetsuju Sekiryu
Scientific Reports 11 ( 1 ) 8464 2021年
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Evidence for activation of lectin and classical pathway complement components in aqueous humor of neovascular age-related macular degeneration
Tomoko Omori, Yasuharu Oguchi, Takeshi Machida, Yutaka Kato, Yumi Ishida, Akira Ojima, Kanako Itagaki, Hiroaki Shintake, Ryutaro Tomita, Akihito Kasai, Yukinori Sugano, Masashi Ogasawara, Hideharu Sekine, and Tetsuju Sekiryu
Ophthalmic Research 63 252 - 258 2020年
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Anaphylatoxin concentration in aqueous and vitreous humor in the eyes with vitreoretinal interface abnormalities
Yasuharu Oguchi, Tetsuju Sekiryu, Tomoko Omori, Yutaka Kato, Masashi Ogasawara, Yukinori Sugano, Kanako Itagaki, Akira Ojima, Takeshi Machida, Hideharu Sekine
Experimental Eye Research 195 108025 2020年