発表論文 Research articles
２０１９年
Hata J, Machida T, Matsuoka K, Hoshi S, Akaihata K, Hiraki H, Suzuki T, Ogawa S, Kataoka M, Haga N, Ishibashi K, Homma Y, Sekina H, Kojima Y.Complement activation by autoantigen recognition in the growth process of benign prostatic hyperplasia.
Sci Rep 9: 20357
Tanaka T, Onuma H, Shigihara T, Kimura E, Fukuta Y, Shirasaka N, Moriyama T, Homma Y.
Anti-osteoporotic effects of syringic acid and vanilic acid in the extracts of waste beds after mushroom cultivation.
J Biosci Bioeng 128: 622-629, 2019
Hayashi M, Machida T, Ishida Y, Ogata Y, Omori T, Takasumi M, Endo Y, Suzuki T, Sekimata M, Homma Y, Ikawa M, Ohira H, Fujita T, Sekine H.
Role of MASP-3 in the physiological activation of factor D of the alternative complement pathway.
J Immunol 203:1411-1416, 2019
Tanaka M, Osaka T, Homma Y, Hanada K, Okumura K, Tomita H.
IQGAP1 activates PLC‐δ1 by direct binding and moving along microtubule with DLC‐1 to cell surface.
FASEB BioAdvances 1: 465-480, 2019
Ogura M, Kikuchi H, Shakespear N, Suzuki T, Yamaki J, Homma MK, Oshima Y, Homma Y.
Prenylated quinolinecarboxylic acid derivative prevents neuronal cell death through inhibition of MKK4.
Biochem Pharmacol 162: 109-122, 2019
２０１７年
Tanaka T, Homma Y, Kawamura Y.Kudzu (Pueraria lobata) Vine Isoflavone, Puerarin, Improves Weight gain, Glucose Metabolism and Osteoporosis and Their Biokinetics in Ovariectomized Mouse.
Advances in Obesity Weight Management & Control 7: 196, 2017
Ogura M, Inoue T, Yamaki J, Homma MK, Kurosaki T, Homma Y.
Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells in mice.
Eur J Immunol 47:406-418
２０１６年
Ogura M, Kikuchi H, Suzuki T, Yamaki J, Homma MK, Oshima Y, Homma Y.Prenylated quinolinecarboxylic derivative suppresses immune responses through inhibition of PAK2.
Biochemical Pharmacol 105:55-65
Riggle MK, Riehle KJ, Kenerson HL, Turnham R, Homma MK, Samelson B, Bauer R, McKnight GS, Scott JD.
Enhanced cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinomas.
Pediatric Research 80:110-8
２０１５年
Kinjo T, Tanaka M, Osanai T, Shibutani S, Narita I, Tanno T, Nishizaki K, Ichikawa H, Kimura Y, Ishida Y, Yokota T, Shimada M, Homma Y, Tomita H, Okumura K.Enhanced p122RhoGAP/DLC-1 expression can be a cause of coronary spasm.
PLoS ONE 10(12): e0143884
Kubohara Y, Komachi M, Homma Y, Kikuchi H, Oshima Y.
Derivatives of Dictyostelium differentiation-inducing factors inhibit lysophosphatidic acid-stimulated migration of murine osteosarcoma LM8 cells.
Biochem Biophys Res Commun 463:800-5
Suzuki T, Kikuchi H, Ogura M, Homma MK, Oshima Y, Homma Y.
Weight loss by Ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold.
PLoS One 10:e0117088
Kikuchi H, Suzuki T, Ogura M, Homma MK, Homma Y, Oshima Y.
Synthesis of prenylated quinolinecarboxylic acid derivatives and their anti-obesity activities.
Bioorg Med Chem 23:66-72
Homma MK, Shibata T, Suzuki T, Ogura M, Kozuka-Hata H, Oyama M, Homma Y.
Role for protein kinase CK2 on cell proliferation: Assessing the components of the CK2 complex in the nucleus during the cell cycle progression.
Protein Kinase CK2 Cellular Function in Normal and Disease States, Advances in Biochemistry in Health and Disease, Eds. by Khalil Ahmed et al., Springer International Publishing Switzerland, Vol.12, P.197-226
２０１４年
Ogura M, Yamaki J, Homma MK, Homma Y.Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species.
FEBS Lett 588:2837-43
Katou Y, Endo N, Suzuki T, Yu J, Kikuchi H, Oshima Y, Homma Y.
Metarhizin A suppresses cell proliferation by inhibiting cytochrome c oxidase activity.
Life Sci 103:1-7
Kubohara Y, Kikuchi H, Matsuo Y, Oshima Y, Homma Y.
Properties of a non-bioactive fluorescent derivative of differentiation-inducing factor-3, an anti-tumor agent found in Dictyostelium discoideum.
Biol Open 3:289-96
２０１３年
Kubohara Y, Kikuchi H, Matsuo Y, Oshima Y, Homma Y.Mitochondria are the target organelle of differentiation-inducing factor-3, an anti-tumor agent isolated from Dictyostelium .
PLoS One 8:e72118
２０１２年
Ogura M, Yamaki J, Homma MK, Homma Y.Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components.
Biochem J 447:281-9
Shibutani S, Osanai T, Ashitate T, Sagara S, Izumiyama K, Yamamoto Y, Hanada K, Echizen T, Tomita H, Fujita T, Miwa T, Matsubara H, Homma Y, Okumura K.
Coronary vasospasm induced in transgenic mouse with increased phospholipase C-δ1 activity.
Circulation 125:1027-36
２０１１年
Sekimata M, Murakami-Sekimata A, Homma Y.CpG methylation prevents YY1-mediated transcriptional activation of the vimentin promoter.
Biochem Biophys Res Commun 414:767-72
２０１０年
p122 protein enhances intracellular calcium increase to Acetylcholine; its possible role in the pathogenesis of coronary spasric angina.
Arterioscler Thromb Vasc Biol, 30: 1968-1975
Takahashi M, Ishida Y, Iwaki D, Kanno K, Suzuki T, Endo Y, Homma Y and Fujita T.
Essential role of mannose-binding lectin-associated serine protease-1 in activation of the complement factor D.
J Exp Med, 207: 29-37
Kabuyama Y, Suzuki T, Nakazawa N, Yamaki J, Homma MK and Homma Y.
Dysregulation of very long chain acyl-CoA dehydrogenase coupled with lipid peroxydation.
Am J Physiol Cell Physiol, 298: C107-C113
２００９年
Comparison of neuropathic pain and neuronal apoptosis following nerve root or spinal code compression.
Eur Spine J, 18: 1978-1985
Kawai K, Iwamae Y, Yamaga M, Kiyota M, Ishii H, Hirata H, Homma Y and Yagisawa H.
Focal adhesion-localization of START-GAP1/DLC1 is essential for cell motility and morphology.
Genes Cells 14: 227-241
２００８年
Cell cycle and activation of CK2.
Mol Cell Biochem 316: 49-55
Kabuyama Y, Kitamura T, Yamaki J, Homma MK, Kikuchi S and Homma Y.
Involvement of thioredoxin reductase 1 in the regulation of redox balance and viability of rheumatoid synovial cells.
Biochem Biophys Res Commun 367: 491-496
Yamaga M, Kawai K, Kiyota M, Homma Y and Yagisawa H.
Recruitment and activation of phospholipase C (PLC)-delta(1) in lipid rafts by muscarinic stimulation of PC12 cells: Contribution of p122RhoGAP/DLC1, a tumor-suppressing PLCdelta(1) binding protein.
Adv Enzyme Regul 48: 41-54
Kitamura T, Kabuyama Y, Kamataki A, Homma MK, Kobayashi H, Aota S, Kikuchi S and Homma Y.
Enhancement of lymphocyte migration and cytokine production by ephrinB1 system in rheumatoid arthritis.
Am J Physiol Cell Physiol 294: C189-196
Suzuki N, Kamataki A, Yamaki J and Homma Y.
Characterization of circulating DNA in healthy human plasma.
Clin Chim Acta 387: 55-58
２００７年
Involvement of selenoprotein P in the regulation of redox balance and myofibroblast viability in idiopathic pulmonary fibrosis.
Genes Cells 12:1235-1244
Kobayashi H, Kitamura T, Sekiguchi M, Homma MK, Kabuyama Y, Konno S, Kikuchi S and Homma Y.
Involvement of EphB1 receptor/ephrinB2 ligand in neuropathic pain.
Spine 32: 1592-1598
Sugino T, Yamaguchi T, Ogura G, Kusakabe T, Goodison S, Homma Y and Suzuki T.
The secretory leukocyte protease inhibitor (SLPI) suppresses cancer cell invasion but promotes blood-borne metastasis via an invasion-independent pathway.
J Pathol 212: 152-60
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