{"id":791,"date":"2012-12-15T02:39:49","date_gmt":"2012-12-14T17:39:49","guid":{"rendered":"http:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/?p=791"},"modified":"2018-04-16T02:40:32","modified_gmt":"2018-04-15T17:40:32","slug":"snap-23%e3%81%af%e3%83%95%e3%82%a1%e3%82%b4%e3%82%bd%e3%83%bc%e3%83%a0%e3%81%ae%e5%bd%a2%e6%88%90%e3%83%bb%e6%88%90%e7%86%9f%e3%81%ab%e6%a9%9f%e8%83%bd%e3%81%99%e3%82%8b","status":"publish","type":"post","link":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/research\/snap-23%e3%81%af%e3%83%95%e3%82%a1%e3%82%b4%e3%82%bd%e3%83%bc%e3%83%a0%e3%81%ae%e5%bd%a2%e6%88%90%e3%83%bb%e6%88%90%e7%86%9f%e3%81%ab%e6%a9%9f%e8%83%bd%e3%81%99%e3%82%8b.html","title":{"rendered":"SNAP-23\u306f\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u30fb\u6210\u719f\u306b\u6a5f\u80fd\u3059\u308b"},"content":{"rendered":"
\n\n\n\n\n\n\n\n\n\n
\u8ad6\u6587\u984c\u540d<\/td>\nSNAP-23 regulates phagosome formation and maturation in macrophages<\/td>\n<\/tr>\n
SNAP-23\u306f\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u30fb\u6210\u719f\u306b\u6a5f\u80fd\u3059\u308b<\/td>\n<\/tr>\n
\u8457\u3000\u3000\u8005<\/td>\n\u6afb\u4e95\u5343\u6075\u3001\u6a4b\u672c\u4ec1\u5fd7\u3001\u4e2d\u897f\u79c0\u6a39\u3001\u8352\u4e95\u6589\u7950\u3001\u548c\u7530\u6d0b\u3001\u548c\u7530\u6208\u8679\u3001
\n\u548c\u7530\u90c1\u592b\u3001\u521d\u6ca2\u6e05\u9686\n<\/td>\n<\/tr>\n
\u96d1\u8a8c\u540d<\/td>\nMol Biol Cell<\/td>\n<\/tr>\n
\u767a\u884c\u65e5<\/td>\n2012\u5e7412\u670815\u65e5<\/td>\n<\/tr>\n
\u5dfb\uff08\u53f7\uff09\u3001\u30da\u30fc\u30b8<\/td>\n23(24):4849-63<\/td>\n<\/tr>\n
\u8981\u3000\u3000\u3000\u65e8<\/td>\n<\/tr>\n
\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u306a\u3069\u306e\u98df\u7d30\u80de\u306b\u898b\u3089\u308c\u308b\u30d5\u30a1\u30b4\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9(\u8caa\u98df)\u306f\u3001\u75c5\u539f\u5fae\u751f\u7269\u306a\u3069\u3092\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0(\u98df\u80de)\u306b\u53d6\u308a\u8fbc\u307f\u3001\u6bba\u83cc\u30fb\u5206\u89e3\u3059\u308b\u751f\u4f53\u9632\u5fa1\u53cd\u5fdc\u306e\u4e00\u3064\u3067\u3042\u308b\u3002\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306f\u30a8\u30f3\u30c9\u30bd\u30fc\u30e0\u3084\u30e9\u30a4\u30bd\u30be\u30fc\u30e0\u306a\u3069\u306e\u7d30\u80de\u5185\u5c0f\u5668\u5b98(\u30aa\u30eb\u30ac\u30cd\u30e9)\u3068\u878d\u5408\u3092\u7e70\u308a\u8fd4\u3057\u6210\u719f\u3059\u308b\u3002\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u3084\u6210\u719f\u306f\u8907\u96d1\u306a\u819c\u878d\u5408\u306b\u3088\u3063\u3066\u9032\u884c\u3059\u308b\u304c\u3001\u305d\u306e\u5206\u5b50\u6a5f\u69cb\u306f\u3088\u304f\u308f\u304b\u3063\u3066\u3044\u306a\u3044\u3002\u305d\u3053\uff53\u3067\u3001\u819c\u878d\u5408\u306b\u6a5f\u80fd\u3059\u308bSNARE\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3001\u30de\u30af\u30ed\u30d5\u30a1\u30fc\u30b8\u7d30\u80de\u819c\u306b\u5c40\u5728\u3059\u308bSNAP-23\u306e\u6a5f\u80fd\u89e3\u6790\u3092\u884c\u3044\u3001\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u3084\u6210\u719f\u306e\u5206\u5b50\u6a5f\u69cb\u3092\u660e\u3089\u304b\u306b\u3059\u308b\u3053\u3068\u3092\u76ee\u7684\u306b\u7814\u7a76\u3092\u884c\u3063\u305f\u3002<\/p>\n

\u305d\u306e\u7d50\u679c\u3001①SNAP-23\u306e\u904e\u5270\u767a\u73fe\u306f\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u3068\u6210\u719f\u3092\u4ea2\u9032\u3057\u305f\u3002\u307e\u305f\u3001②SNAP-23\u306e\u767a\u73fe\u6291\u5236\u7d30\u80de\u3067\u306f\u3001\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u30fb\u6210\u719f\u306e\u4e21\u904e\u7a0b\u304c\u963b\u5bb3\u3055\u308c\u305f\u3002①\u3068②\u304b\u3089\u3001SNAP-23\u306f\u30d5\u30a1\u30b4\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u306b\u304a\u3051\u308b\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u304a\u3088\u3073\u6210\u719f\u306b\u6a5f\u80fd\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002\u6b21\u306b\u3001③\u5b9f\u969b\u306b\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u819c\u4e0a\u3067SNAP-23\u304c\u6a5f\u80fd\u3057\u3066\u3044\u308b\u304b\u3092\u8abf\u3079\u308b\u305f\u3081FRET(\u86cd\u5149\u5171\u9cf4\u30a8\u30cd\u30eb\u30ae\u30fc\u79fb\u52d5)\u89e3\u6790\u3092\u884c\u3063\u305f\u3068\u3053\u308d\u3001SNARE\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3042\u308bVAMP7\u3092\u904e\u5270\u767a\u73fe\u3057\u305f\u5834\u5408\u306bFRET\u30b7\u30b0\u30ca\u30eb\u306e\u5897\u52a0\u304c\u898b\u3089\u308c\u305f\u3002\u3053\u306e\u3053\u3068\u304b\u3089\u3001SNAP-23\u306f\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u819c\u4e0a\u3067\u819c\u878d\u5408\u306b\u4f34\u3046\u69cb\u9020\u5909\u5316\u3092\u8d77\u3053\u3057\u3066\u3044\u308b\u3053\u3068\u3001\u3064\u307e\u308a\u3001\u5b9f\u969b\u306b\u6a5f\u80fd\u3057\u3066\u3044\u308b\u3053\u3068\u304c\u793a\u5506\u3055\u308c\u305f\u3002<\/p>\n

\u4ee5\u4e0a\u3088\u308a\u3001SNAP-23\u306f\u819c\u878d\u5408\u88c5\u7f6e\u3068\u3057\u3066\u30d5\u30a1\u30b4\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u306b\u6a5f\u80fd\u3059\u308b\u3053\u3068\u304c\u660e\u3089\u304b\u3068\u306a\u3063\u305f\u3002\n<\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

\u8ad6\u6587\u984c\u540d SNAP-23 regulates phagosome formation and maturation in macrophages SNAP-23\u306f\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u306e\u5f62\u6210\u30fb\u6210\u719f\u306b\u6a5f\u80fd\u3059\u308b \u8457…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,4,19],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts\/791"}],"collection":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/comments?post=791"}],"version-history":[{"count":1,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts\/791\/revisions"}],"predecessor-version":[{"id":792,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts\/791\/revisions\/792"}],"wp:attachment":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/media?parent=791"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/categories?post=791"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/tags?post=791"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}