{"id":785,"date":"2012-03-31T02:35:39","date_gmt":"2012-03-30T17:35:39","guid":{"rendered":"http:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/?p=785"},"modified":"2018-04-16T02:37:26","modified_gmt":"2018-04-15T17:37:26","slug":"%e5%8d%98%e7%9b%b8%e6%80%a74%e9%80%a3%e7%99%ba%e7%a3%81%e6%b0%97%e5%88%ba%e6%bf%80%e6%b3%95%ef%bc%88qps%ef%bc%89%e3%81%ab%e3%82%88%e3%82%8b%e5%88%ba%e6%bf%80%e9%81%8b%e5%8b%95%e7%9a%ae%e8%b3%aa","status":"publish","type":"post","link":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/research\/seika\/%e5%8d%98%e7%9b%b8%e6%80%a74%e9%80%a3%e7%99%ba%e7%a3%81%e6%b0%97%e5%88%ba%e6%bf%80%e6%b3%95%ef%bc%88qps%ef%bc%89%e3%81%ab%e3%82%88%e3%82%8b%e5%88%ba%e6%bf%80%e9%81%8b%e5%8b%95%e7%9a%ae%e8%b3%aa.html","title":{"rendered":"\u5358\u76f8\u60274\u9023\u767a\u78c1\u6c17\u523a\u6fc0\u6cd5\uff08QPS\uff09\u306b\u3088\u308b\u523a\u6fc0\u904b\u52d5\u76ae\u8cea\u5185\u306e\u8133\u5185\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u6fc3\u5ea6\u5909\u5316"},"content":{"rendered":"<br \/>\n<table width=\"550\" border=\"1\" cellpadding=\"3\" cellspacing=\"0\" bordercolor=\"#4470A5\" class=\"table\">\n<tr>\n<td width=\"102\" rowspan=\"2\" align=\"center\" bgcolor=\"#D0DDF1\">\u8ad6\u6587\u984c\u540d<\/td>\n<td width=\"430\" bgcolor=\"#FFFFCC\">Quadri\u2010pulse stimulation induces stimulation frequency dependent cortical hemoglobin concentration changes within the ipsilateral motor cortical network<\/td>\n<\/tr>\n<tr>\n<td>\u5358\u76f8\u60274\u9023\u767a\u78c1\u6c17\u523a\u6fc0\u6cd5\uff08QPS\uff09\u306b\u3088\u308b\u523a\u6fc0\u904b\u52d5\u76ae\u8cea\u5185\u306e\u8133\u5185\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\u6fc3\u5ea6\u5909\u5316<\/td>\n<\/tr>\n<tr>\n<td align=\"center\" bgcolor=\"#D0DDF1\">\u8457\u3000\u3000\u8005<\/td>\n<td>\u30b0\u30ed\u30a4\u30b9\u7d14\u3001\u671b\u6708\u4ec1\u5fd7\u3001\u53e4\u6797\u4fca\u6643\u3001\u5c0f\u6797\u4fca\u8f14\u3001\u698e\u672c\u96ea\u3001\u4e2d\u6751\u8015\u4e00\u90ce\u3001\u5b87\u5ddd\u7fa9\u4e00<\/td>\n<\/tr>\n<tr>\n<td align=\"center\" bgcolor=\"#D0DDF1\">\u96d1\u8a8c\u540d<\/td>\n<td>Brain Stimulation<\/td>\n<\/tr>\n<tr>\n<td align=\"center\" bgcolor=\"#D0DDF1\">\u767a\u884c\u65e5<\/td>\n<td>2012\u5e743\u6708<\/td>\n<\/tr>\n<tr>\n<td align=\"center\" bgcolor=\"#D0DDF1\">\u5dfb\uff08\u53f7\uff09\u3001\u30da\u30fc\u30b8<\/td>\n<td>6\uff081\uff0940\u201048<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\" align=\"center\" bgcolor=\"#D0DDF1\">\u8981\u3000\u3000\u3000\u65e8<\/td>\n<\/tr>\n<tr>\n<td colspan=\"2\">\u5358\u76f8\u60274\u9023\u767a\u78c1\u6c17\u523a\u6fc0\u6cd5\uff08QPS\uff09\u306f\u3001\u5927\u8133\u76ae\u8cea\u306b\u5bfe\u3057\u3066\u3001\u523a\u6fc0\u5468\u6ce2\u6570\u4f9d\u5b58\u6027\u306b\u8208\u596e\u6027\/\u6291\u5727\u6027\u306e\u53cc\u65b9\u5411\u6027\u306e\u9577\u671f\u53ef\u5851\u6027\uff08long term potentiation, LTP\uff0flong term depression\uff0cLTD\uff09\u3092\u8a98\u5c0e\u3059\u308b\u3002\u7279\u306b\u30014\u3064\u306e\u5358\u76f8\u6027\u523a\u6fc0\u306e\u523a\u6fc0\u9593\u9694\uff08inter\u2010pulse interval\uff0cIPI\uff09\u30925mm\uff0f50mm\u3068\u3057\u305f\u969b\u306eLTP\uff0fLTD\u52b9\u679c\u304c\u6700\u3082\u5927\u304d\u3044\u3002\u672c\u7814\u7a76\u3067\u306f\u3001\u8fd1\u8d64\u5916\u7dda\u5206\u5149\u6cd5\uff08&#186;near\u2010infrared spectroscopy\uff0cNIRS\uff09\u3092\u7528\u3044\u3066\u3001\u30d2\u30c8\u306e1\u6b21\u904b\u52d5\u91ce\uff08M1\uff09\u3092QPS\u3067\u523a\u6fc0\u3057\u305f\u969b\u306b\u3001\u523a\u6fc0\u76f4\u4e0b\u306e\u8133\u8840\u6d41\u306b\u4e0e\u3048\u308b\u52b9\u679c\u3092\u691c\u8a0e\u3057\u305f\u3002\u305d\u306e\u7d50\u679c\u3001\u523a\u6fc0\u5468\u6ce2\u6570\u4f9d\u5b58\u6027\u306b\u8a98\u5c0e\u3055\u308c\u308b\u53cc\u65b9\u5411\u6027\u306e\u9577\u671f\u53ef\u5851\u6027\u3068\u306f\u7570\u306a\u308a\u3001M1\u5185\u306e\u9178\u7d20\u5316\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\uff08oxy\u2010Hb\uff09\u306f\u4f4e\u4e0b\u3057\u305f\u306e\u307f\u3067\u3042\u308a\uff08\u5358\u65b9\u5411\u6027\u5909\u5316\uff09\u3001\u9ad8\u5468\u6ce2\u6570\u523a\u6fc0\u306b\u304a\u3044\u3066\u6709\u610f\u306b\u4f4e\u4e0b\u3057\u3066\u3044\u305f\u3002\u307e\u305f\u3001\u9ad8\u983b\u5ea6QPS\u306b\u3088\u308bM1\u523a\u6fc0\u306fM1\u306e\u307f\u306a\u3089\u305a\u524d\u904b\u52d5\u91ce\u306eoxy\u2010Hb\u3082\u4f4e\u4e0b\u3055\u305b\u305f\u3053\u3068\u304b\u3089\u3001QPS\u306b\u3088\u308bM1\u523a\u6fc0\u306f\u5927\u8133\u76ae\u8cea\u30cd\u30c3\u30c8\u30ef\u2010\u30af\u3092\u4ecb\u3057\u3066\u5e83\u7bc4\u306b\u4f5c\u7528\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u305f\u3002<\/p>\n<p>\u8131\u9178\u7d20\u5316\u30d8\u30e2\u30b0\u30ed\u30d3\u30f3\uff08deoxy\u2010Hb\uff09\u306e\u5909\u5316\u3092\u4f34\u308f\u306a\u3044oxy\u2010Hb\u306e\u6e1b\u5c11\u306f\u3001\u76ae\u8cea\u306e\u6d3b\u52d5\u6027\u4f4e\u4e0b\u3092\u793a\u5506\u3057\u3066\u3044\u308b\u3002\u9ad8\u983b\u5ea6QPS\u3067oxy\u2010Hb\u304c\u6e1b\u5c11\u3057\u305f\u3068\u3044\u3046\u7814\u7a76\u7d50\u679c\u306f\u3001QPS\u306b\u3088\u308a\u751f\u3058\u308b\u5927\u8133\u76ae\u8cea\u306e\u9577\u671f\u53ef\u5851\u6027\u5909\u5316\u3068\u8133\u8840\u6d41\u5909\u5316\u3068\u3067\u3001\u4e21\u8005\u306e\u767a\u751f\u6a5f\u5e8f\u304c\u7570\u306a\u308b\u3053\u3068\u3092\u793a\u5506\u3059\u308b\u3002\u9310\u4f53\u8def\u30cb\u30e5\u2010\u30ed\u30f3\u306e\u6291\u5236\u6027\u30b7\u30ca\u30d7\u30b9\u5f8c\u96fb\u4f4d\uff08inhibitory postsynaptic potentials\uff0cIPSPs\uff09\u306e\u56de\u5fa9\u306f\u3001\u8208\u596e\u6027\u30b7\u30ca\u30d7\u30b9\u5f8c\u96fb\u4f4d\uff08excitatory postsynaptic potential\uff0cEPSPs\uff09\u306b\u6bd4\u3057\u3066\u9045\u3044\u3053\u3068\u304b\u3089\u3001\u9ad8\u983b\u5ea6QPS\u3067IPSPs\u306e\u91cd\u5408\u306b\u3088\u308b\u6291\u5727\u52b9\u679c\u304c\u7d2f\u7a4d\u3059\u308b\u305f\u3081\u306b\u3001\u4f4e\u983b\u5ea6QPS\u306b\u6bd4\u3057\u3066\u8133\u8840\u6d41\u4f4e\u4e0b\u304c\u751f\u3058\u305f\u306e\u3067\u306f\u306a\u3044\u304b\u3068\u63a8\u5bdf\u3055\u308c\u308b\u3002\n<\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>\u8ad6\u6587\u984c\u540d Quadri\u2010pulse stimulation induces stimulation frequency dependent cortical hemoglobin 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