{"id":1110,"date":"2011-10-05T10:07:11","date_gmt":"2011-10-05T01:07:11","guid":{"rendered":"http:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/?p=1110"},"modified":"2018-04-17T10:08:47","modified_gmt":"2018-04-17T01:08:47","slug":"nirf%e3%81%af%e7%b4%b0%e8%83%9e%e5%91%a8%e6%9c%9f%e3%83%8d%e3%83%83%e3%83%88%e3%83%af%e3%83%bc%e3%82%af%e3%81%ae%e4%b8%ad%e5%bf%83%e3%81%ab%e4%bd%8d%e7%bd%ae%e3%81%97%ef%bc%8c%e7%99%8c%e6%8a%91-2","status":"publish","type":"post","link":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/research\/nirf%e3%81%af%e7%b4%b0%e8%83%9e%e5%91%a8%e6%9c%9f%e3%83%8d%e3%83%83%e3%83%88%e3%83%af%e3%83%bc%e3%82%af%e3%81%ae%e4%b8%ad%e5%bf%83%e3%81%ab%e4%bd%8d%e7%bd%ae%e3%81%97%ef%bc%8c%e7%99%8c%e6%8a%91-2.html","title":{"rendered":"NIRF\u306f\u7d30\u80de\u5468\u671f\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u4e2d\u5fc3\u306b\u4f4d\u7f6e\u3057\uff0c\u764c\u6291\u5236\u907a\u4f1d\u5b50\u306e\u5019\u88dc\u3067\u3042\u308b"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n
\u8ad6\u6587\u984c\u540d<\/td>\nNIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor.<\/td>\n<\/tr>\n
NIRF\u306f\u7d30\u80de\u5468\u671f\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u4e2d\u5fc3\u306b\u4f4d\u7f6e\u3057\uff0c\u764c\u6291\u5236\u907a\u4f1d\u5b50\u306e\u5019\u88dc\u3067\u3042\u308b\u3002<\/td>\n<\/tr>\n
\u8457\u3000\u3000\u8005<\/td>\n\u68ee \u52aa\u3001\u6c60\u7530\u5927\u7950\u3001\u798f\u5cf6\u4fca\u5f66\u3001\u7af9\u4e4b\u4e0b\u8aa0\u4e00\u3001\u9ad8\u5730\u82f1\u592b<\/td>\n<\/tr>\n
\u96d1\u8a8c\u540d<\/td>\nCell Cycle<\/td>\n<\/tr>\n
\u767a\u884c\u65e5<\/td>\n2011\u5e7410\u67081\u65e5<\/td>\n<\/tr>\n
\u5dfb\uff08\u53f7\uff09\u3001\u30da\u30fc\u30b8<\/td>\n10(19):3284-99<\/td>\n<\/tr>\n
\u8981\u3000\u3000\u3000\u65e8<\/td>\n<\/tr>\n
\u751f\u4f53\u306e\u5206\u5b50\u9593\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306b\u306f\uff0c\u591a\u6570\u306e\u76f8\u4e92\u4f5c\u7528\u56e0\u5b50\u3092\u6301\u3064Hub\u30bf\u30f3\u30d1\u30af\u304c\u5c11\u6570\u5b58\u5728\u3057\uff0c\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u5b8c\u5168\u6027\u3068\u6a5f\u80fd\u3092\u4fdd\u3064\u91cd\u8981\u306a\u5f79\u76ee\u3092\u679c\u305f\u3057\u3066\u3044\u308b\u3002\u7d30\u80de\u5468\u671f\u306e\u5236\u5fa1\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306f\uff0c\u591a\u6570\u306e\u6a5f\u80fd\u30e2\u30b8\u30e5\u30fc\u30eb\u9593\u306e\u76f8\u4e92\u4f5c\u7528\u306b\u3088\u308a\u5e83\u7bc4\u306a\u7d30\u80de\u6a5f\u80fd\u3092\u8abf\u7bc0\u3057\u3066\u3044\u308b\u3002\u9006\u306b\u305d\u306e\u7570\u5e38\u306f\uff0c\u7d30\u80de\u6a5f\u80fd\u306e\u591a\u5c90\u306b\u308f\u305f\u308b\u969c\u5bb3\u304b\u3089\u7d30\u80de\u764c\u5316\u3092\u3072\u304d\u8d77\u3053\u3059\u3002\u3057\u304b\u3057\uff0c\u30e2\u30b8\u30e5\u30fc\u30eb\u76f8\u4e92\u306e\u6a5f\u80fd\u8abf\u6574\u304c\uff0c\u3044\u304b\u306a\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u69cb\u7bc9\u3068\u5206\u5b50\u7684\u57fa\u76e4\u3067\u652f\u3048\u3089\u308c\u3066\u3044\u308b\u306e\u304b\u306f\u4e0d\u660e\u3067\u3042\u308b\u3002
\n
\n\u68ee\u3089\u304c\u767a\u898b\u3057\u305fNIRF\u306f\u7d30\u80de\u5468\u671f\u505c\u6b62\u3092\u8d77\u3053\u3059\u30e6\u30d3\u30ad\u30c1\u30f3\u30ea\u30ac\u30fc\u30bc\u3067\u3042\u308a\uff0c\u672c\u7814\u7a76\u306b\u304a\u3044\u3066\u8907\u6570\u306ecyclin\uff0cpRB\uff0cp53\u3068\u76f8\u4e92\u4f5c\u7528\u3059\u308b\u3053\u3068\uff0ccyclin D1\u3068E1\u3092\u5171\u306b\u30e6\u30d3\u30ad\u30c1\u30f3\u5316\u3059\u308b\u3053\u3068\u3092\u793a\u3057\u305f\u3002NIRF\u304c\u5f62\u6210\u3059\u308b\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u7279\u6027\u3092\uff0c\u30b7\u30b9\u30c6\u30e0\u30d0\u30a4\u30aa\u30ed\u30b8\u30fc\u306e\u624b\u6cd5\u3092\u7528\u3044\u3066\u89e3\u6790\u3057\u305f\u3068\u3053\u308d\uff0cNIRF\u306f\u7d30\u80de\u5468\u671f\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u307f\u306a\u3089\u305a\u7d30\u80de\u5185\u60c5\u5831\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u5168\u4f53\u306b\u304a\u3044\u3066\u4e2d\u5fc3\u7684\u4f4d\u7f6e\u3092\u5360\u3081\u308b\u5206\u5b50\u3067\u3042\u308b\u3053\u3068\uff0c\u591a\u6570\u306e\u6a5f\u80fd\u30e2\u30b8\u30e5\u30fc\u30eb\u9593\u306e\u6a5f\u80fd\u8abf\u6574\u306b\u95a2\u4e0e\u3059\u308b\u5206\u5b50\u7fa4(Intermodular Hub)\u3067\u3042\u308b\u3053\u3068\u304c\u5224\u660e\u3057\u305f\u3002
\nIntermodular Hub\u306f\uff0c\u767a\u764c\u306b\u95a2\u308f\u308b\u983b\u5ea6\u306e\u9ad8\u3044\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u308b\u304c\u3001\u5b9f\u969b\u306bNIRF\u907a\u4f1d\u5b50\u306f\u591a\u7a2e\u985e\u306e\u764c\u3067\u6b20\u5931\u3057\u3066\u3044\u305f\u3002\u7279\u306b\u91cd\u8981\u306a\u306e\u306f\uff0c\u80ba\u306e\u975e\u5c0f\u7d30\u80de\u764c\u3067NIRF\u3092\u6a19\u7684\u3068\u3059\u308b\u5fae\u5c0f\u6b20\u5931\u304c\u767a\u898b\u3055\u308c\u305f\u3053\u3068\u3067\u3042\u308b\u3002\u3053\u306e\u6b20\u5931\u90e8\u4f4d\u306b\u5927\u8178\u764c\u3068\u95a2\u9023\u3059\u308bSNP\u304c\u5b58\u5728\u3059\u308b\u3053\u3068\u306f\uff0cNIRF\u304c\u764c\u3068\u95a2\u4fc2\u3059\u308b\u53ef\u80fd\u6027\u3092\u5f37\u304f\u793a\u5506\u3059\u308b\u3002
\n
\n\u4ee5\u4e0a\u306e\u77e5\u898b\u306f\uff0cNIRF\u304c\u7d30\u80de\u5468\u671f\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u4e2d\u3067\u969b\u3060\u3063\u305f\u4f4d\u7f6e\u3092\u5360\u3081\u308b\u30bf\u30f3\u30d1\u30af\u3067\u3042\u308b\u3053\u3068\u3068\uff0c\u65b0\u898f\u306e\u764c\u6291\u5236\u907a\u4f1d\u5b50\u3067\u3042\u308b\u3053\u3068\u3092\u5f37\u304f\u793a\u5506\u3057\u3066\u3044\u308b\u3002<\/p>\n

\u3014\u8a73\u7d30\u7d39\u4ecb\u30da\u30fc\u30b8\u3015<\/span>
\n\u25cf<\/span> \u751f\u547d\u79d1\u5b66\u90e8\u9580\u3000\u68ee\u52aa\u51c6\u6559\u6388\u300cNIRF\u30d7\u30ed\u30b8\u30a7\u30af\u30c8\u300d\u5171\u540c\u7814\u7a76\u30b0\u30eb\u30fc\u30d7
\n \u7d30\u80de\u5185\u60c5\u5831\u30cd\u30c3\u30c8\u30ef\u30fc\u30af\u306e\u4e2d\u5fc3\u56e0\u5b50 \u300cNIRF\u300d \u3092\u767a\u898b \u2015 \u764c\u306a\u3069\u306e\u30d2\u30c8\u75be\u60a3\u306b\u95a2\u9023\u3059\u308b\u907a\u4f1d\u5b50 \u2015<\/a>
\n \u7c73\u56fd\u3000\u79d1\u5b66\u96d1\u8a8c \u300cCell Cycle\u300d<\/a> 2011\u5e7410\u6708\u53f7 \u30aa\u30f3\u30e9\u30a4\u30f3\u7248 \uff0810\u67081\u65e5\u4ed8 \u3014\u65e5\u672c\u6642\u959310\u67082\u65e5\u3015\uff09<\/a>
\n \uff082011.10.05\uff09 <\/td>\n<\/tr>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

\u8ad6\u6587\u984c\u540d NIRF constitutes a nodal point in the cell cycle network and is a candidate tumor suppressor. N…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,4,20],"tags":[],"acf":[],"_links":{"self":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts\/1110"}],"collection":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/comments?post=1110"}],"version-history":[{"count":1,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts\/1110\/revisions"}],"predecessor-version":[{"id":1111,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/posts\/1110\/revisions\/1111"}],"wp:attachment":[{"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/media?parent=1110"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/categories?post=1110"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.fmu.ac.jp\/univ\/kenkyuseika\/wp-json\/wp\/v2\/tags?post=1110"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}