論文 - 岡山 洋和
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憩室内に発生した早期S状結腸癌を腹腔鏡補助下に局所切除した1例
千田 峻, 木口 託見, 深井 智司, 伊藤 美郷, 芦澤 舞, 小野澤 寿志, 岡山 洋和, 坂本 渉, 齋藤 元伸, 門馬 智之, 河野 浩二
癌と化学療法 51 ( 13 ) 1312 - 1314 2024年12月
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High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8(+) T cells in dMMR/MSI-H gastric cancer.
Kanoda R, Nakajima S, Fukai S, Saito M, Saito K, Suzuki H, Kikuchi T, Nirei A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K
Scientific reports 14 ( 1 ) 20859 2024年9月
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胃癌におけるHER2シグナルを介した腫瘍微小環境の制御 HER2過剰発現の腫瘍内不均一性を呈する胃癌症例からの検討
中嶋正太郎, 深井 智司, 金田 晃尚, 圓谷 秀哲, 松石 彬, 岡山 洋和, 齋藤 元伸, 三村 耕作, 坂本 渉, 佐瀬 善一郎, 門馬 智之, 河野 浩二
癌と化学療法 51 ( 9 ) 903 - 905 2024年9月
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The impact of CLDN18.2 expression on effector cells mediating antibody-dependent cellular cytotoxicity in gastric cancer.
Matsuishi A, Nakajima S, Saito M, Saito K, Fukai S, Tsumuraya H, Kanoda R, Kikuchi T, Nirei A, Kaneta A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K
Scientific reports 14 ( 1 ) 17916 2024年8月
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Tumor Infiltrating Effector Regulatory T Cells Express VEGF Receptor 2 in Patients With Colorectal Cancer.
Tsumuraya H, Mimura K, Nakajima S, Hanayama H, Matsuishi A, Okayama H, Fukai S, Ito M, Ashizawa M, Chida S, Onozawa H, Sakamoto W, Saito M, Saze Z, Momma T, Kono K
Anticancer research 44 ( 7 ) 2933 - 2941 2024年7月
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TIM-3 Expression on Dendritic Cells in Colorectal Cancer.
Sakuma M, Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Fukai S, Tsumuraya H, Onozawa H, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
Cancers 16 ( 10 ) 1888 - 1888 2024年5月( ISSN:2072-6694 )
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TGFβ-Responsive Stromal Activation Occurs Early in Serrated Colorectal Carcinogenesis.
Tsumuraya H, Okayama H, Katagata M, Matsuishi A, Fukai S, Ito M, Sakamoto W, Saito M, Momma T, Nakajima S, Mimura K, Kono K
International journal of molecular sciences 25 ( 9 ) 4626 - 4626 2024年4月
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The tumor cell-intrinsic cGAS-STING pathway is associated with the high density of CD8(+) T cells after chemotherapy in esophageal squamous cell carcinoma.
Matsuishi A, Nakajima S, Kaneta A, Saito K, Fukai S, Sakuma M, Tsumuraya H, Okayama H, Saito M, Mimura K, Nirei A, Kikuchi T, Hanayama H, Saze Z, Sakamoto W, Momma T, Kono K
Esophagus : official journal of the Japan Esophageal Society 21 ( 2 ) 165 - 175 2024年4月( ISSN:1612-9059 )
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放射線治療による腫瘍細胞内cGAS-STING経路を介した食道扁平上皮癌微小環境の変化
中嶋正太郎, 三村耕作, 金田晃尚, 片方雅紀, 岡山洋和, 齋藤元伸, 佐瀬善一郎, 花山寛之, 多田武志, 門馬智之, 河野浩二
癌と化学療法 50 ( 10 ) 1099 - 1101 2023年10月
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Down-regulation of stimulator of interferon genes (STING) expression and CD8(+) T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.
Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K
Gastric cancer 26 ( 6 ) 878 - 890 2023年8月
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A Potential Biomarker of Dynamic Change in Peripheral CD45RA(-)CD27(+)CD127(+) Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma.
Sakuma M, Mimura K, Nakajima S, Kaneta A, Kikuchi T, Nirei A, Tada T, Hanayama H, Okayama H, Sakamoto W, Saito M, Momma T, Saze Z, Kono K
Cancers 15 ( 14 ) 3641 2023年7月( ISSN:2072-6694 )
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The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8(+) T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer.
Nakajima S, Kaneta A, Okayama H, Saito K, Kikuchi T, Endo E, Matsumoto T, Fukai S, Sakuma M, Sato T, Mimura K, Saito M, Saze Z, Sakamoto W, Onozawa H, Momma T, Kono K
Cancers 15 ( 10 ) 2826 2023年5月( ISSN:2072-6694 )
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Radiation-Induced Remodeling of the Tumor Microenvironment Through Tumor Cell-Intrinsic Expression of cGAS-STING in Esophageal Squamous Cell Carcinoma.
Nakajima S, Mimura K, Kaneta A, Saito K, Katagata M, Okayama H, Saito M, Saze Z, Watanabe Y, Hanayama H, Tada T, Sakamoto W, Momma T, Ohira H, Kono K
International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2023年3月( ISSN:0360-3016 )
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M2 tumor-associated macrophages resist to oxidative stress through heme oxygenase-1 in the colorectal cancer tumor microenvironment.
Ito M, Mimura K, Nakajima S, Okayama H, Saito K, Nakajima T, Kikuchi T, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Kono K
Cancer immunology, immunotherapy : CII 72 ( 7 ) 2233 - 2244 2023年3月( ISSN:0340-7004 )
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ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.
Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 3 ) 379 - 392 2023年2月( ISSN:1436-3291 )
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Matsumoto T, Ohki S, Kaneta A, Matsuishi A, Maruyama Y, Yamada L, Tada T, Hanayama H, Watanabe Y, Hayase S, Okayama H, Sakamoto W, Momma T, Saze Z, Kono K
BMC surgery 23 ( 1 ) 8 2023年1月
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TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer.
Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, Fukai S, Endo E, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
Cancers 15 ( 20 ) 4943 2023年
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Clinical outcomes of laparoscopic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumor.
Hanayama H, Katagata M, Sato T, Nakano H, Matsumoto T, Tada T, Watanabe Y, Hayase S, Okayama H, Momma T, Kato T, Hashimoto M, Nakamura J, Hikichi T, Saze Z, Kono K
Fukushima journal of medical science 68 ( 3 ) 169 - 174 2022年12月
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Immune escape mechanism behind resistance to anti-PD-1 therapy in gastrointestinal tract metastasis in malignant melanoma patients with multiple metastases.
Ito M, Mimura K, Nakajima S, Saito K, Min AKT, Okayama H, Saito M, Momma T, Saze Z, Ohtsuka M, Yamamoto T, Kono K
Cancer immunology, immunotherapy : CII 71 ( 9 ) 2293 - 2300 2022年9月
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Short-term outcomes of neoadjuvant chemotherapy with capecitabine plus oxaliplatin for patients with locally advanced rectal cancer followed by total or tumor-specific mesorectal excision with or without lateral pelvic lymph node dissection.
Sakamoto W, Kanke Y, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Kono K
Fukushima journal of medical science 68 ( 2 ) 89 - 95 2022年8月( ISSN:0016-2590 )
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Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer.
Kaneta A, Nakajima S, Okayama H, Matsumoto T, Saito K, Kikuchi T, Endo E, Ito M, Mimura K, Kanke Y, Saito M, Saze Z, Fujita S, Sakamoto W, Onozawa H, Momma T, Ohki S, Kono K
Cancer immunology, immunotherapy : CII 71 ( 11 ) 2765 - 2776 2022年4月( ISSN:0340-7004 )
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Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K
British journal of cancer 126 ( 6 ) 917 - 926 2022年4月( ISSN:0007-0920 )
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Incidence of upper extremity deep vein thrombosis in the retrosternal reconstruction after esophagectomy.
Yamada L, Saito M, Suzuki H, Mochizuki S, Endo E, Kase K, Ito M, Nakano H, Yamauchi N, Matsumoto T, Kaneta A, Kanke Y, Onozawa H, Hanayama H, Okayama H, Fujita S, Sakamoto W, Watanabe Y, Hayase S, Saze Z, Momma T, Ohki S, Kono K
BMC surgery 22 ( 1 ) 91 2022年3月
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マイクロRNAによるPD-L1の制御機構 -The Best of the AACR Journals-
河野浩二, 岡山洋和, 芦澤舞
光が丘 51 62 - 63 2022年2月
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Immune escape mechanism behind resistance to anti-PD-1 therapy in gastrointestinal tract metastasis in malignant melanoma patients with multiple metastases.
Ito M, Mimura K, Nakajima S, Saito K, Min AKT, Okayama H, Saito M, Momma T, Saze Z, Ohtsuka M, Yamamoto T, Kono K
Cancer immunology, immunotherapy : CII 2022年1月( ISSN:0340-7004 )
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High Risk Stage II大腸癌におけるGlasgow Prognostic Scoreの意義と治療戦略
大木 進司, 岡山 洋和, 千田 峻, 坂本 渉, 藤田 正太郎, 齋藤 元伸, 門馬 智之, 佐瀬 善一郎, 河野 浩二
癌と化学療法 48 ( 13 ) 1770 - 1773 2021年12月( ISSN:0385-0684 )
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Matsumoto T, Okayama H, Nakano H, Ito M, Nakajima S, Saito M, Saze Z, Momma T, Mimura K, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 10 ) 1275 - 1277 2021年10月( ISSN:03850684 )
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Neupane P, Mimura K, Nakajima S, Okayama H, Ito M, Thar Min AK, Saito K, Onozawa H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Kono K
Anticancer research 41 ( 10 ) 4895 - 4905 2021年10月( ISSN:0250-7005 )
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ミスマッチ修復機構欠損大腸癌における糖鎖抗原を標的とした免疫療法の可能性
松本拓朗, 岡山洋和, 仲野宏, 伊藤美郷, 中嶋正太郎, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 河野浩二
癌と化学療法 48 ( 10 ) 1275 - 1277 2021年10月( ISSN:0385-0684 )
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Validation of Gene Expression-Based Predictive Biomarkers for Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.
Momma T, Okayama H, Kanke Y, Fukai S, Onozawa H, Fujita S, Sakamoto W, Saito M, Ohki S, Kono K
Cancers 13 ( 18 ) 4642 - 4642 2021年9月
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The role of KRT17 in colorectal cancer.
Ujiie D, Okayama H, Kono K
Aging 13 ( 16 ) 19950 - 19951 2021年8月
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Nakajima S, Mimura K, Matsumoto T, Thar Min AK, Ito M, Nakano H, Neupane P, Kanke Y, Okayama H, Saito M, Momma T, Watanabe Y, Hanayama H, Hayase S, Saze Z, Kono K
Scientific reports 11 ( 1 ) 16891 - 16891 2021年8月
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術前確定診断された肺癌胃転移に対して腹腔鏡下切除術を施行した1例
望月 翔太朗, 山田 玲央, 加瀬 晃志, 伊藤 美郷, 仲野 宏, 山内 直人, 松本 拓朗, 金田 晃尚, 菅家 康之, 中島 隆宏, 花山 寛之, 渡辺 洋平, 小野澤 寿志, 早瀬 傑, 岡山 洋和, 藤田 正太郎, 坂本 渉, 齋藤 元伸, 門馬 智之, 佐瀬 善一郎, 三村 耕作, 大木 進司, 河野 浩二
癌と化学療法 48 ( 8 ) 1057 - 1060 2021年8月( ISSN:0385-0684 )
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A Case of Laparoscopic Surgery for Preoperatively Diagnosed Gastric Metastasis of Lung Cancer
Mochizuki S, Yamada L, Kase K, Ito M, Nakano H, Yamauchi N, Matsumoto T, Kaneta A, Kanke Y, Nakajima T, Hanayama H, Watanabe Y, Onozawa H, Hayase S, Okayama H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Mimura K, Ohki S, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 8 ) 1057 - 1060 2021年8月( ISSN:03850684 )
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Circulating tumor cells after neoadjuvant chemotherapy are related with recurrence in esophageal squamous cell carcinoma.
Ujiie D, Matsumoto T, Endo E, Okayama H, Fujita S, Kanke Y, Watanabe Y, Hanayama H, Hayase S, Saze Z, Ohki S, Kono K
Esophagus : official journal of the Japan Esophageal Society 18 ( 3 ) 566 - 573 2021年7月( ISSN:1612-9059 )
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Stromal expression of cancer-associated fibroblast-related molecules, versican and lumican, is strongly associated with worse relapse-free and overall survival times in patients with esophageal squamous cell carcinoma.
Yamauchi N, Kanke Y, Saito K, Okayama H, Yamada S, Nakajima S, Endo E, Kase K, Yamada L, Nakano H, Matsumoto T, Hanayama H, Watanabe Y, Hayase S, Saito M, Saze Z, Mimura K, Momma T, Oki S, Hashimoto Y, Kono K
Oncology letters 21 ( 6 ) 445 - 445 2021年6月( ISSN:1792-1074 )
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Neoadjuvant Chemotherapy Induces IL34 Signaling and Promotes Chemoresistance via Tumor-Associated Macrophage Polarization in Esophageal Squamous Cell Carcinoma.
Nakajima S, Mimura K, Saito K, Thar Min AK, Endo E, Yamada L, Kase K, Yamauchi N, Matsumoto T, Nakano H, Kanke Y, Okayama H, Saito M, Neupane P, Saze Z, Watanabe Y, Hanayama H, Hayase S, Kaneta A, Momma T, Ohki S, Ohira H, Kono K
Molecular cancer research : MCR 19 ( 6 ) 1085 - 1095 2021年6月( ISSN:1541-7786 )
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Long-term Outcomes of Lower Rectal Cancer Patients Treated with Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection after Preoperative Radiotherapy or Chemoradiotherapy.
Sakamoto W, Ohki S, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Takenoshita S, Kono K
Journal of the anus, rectum and colon 5 ( 2 ) 129 - 136 2021年4月
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EML4-ALK induces cellular senescence in mortal normal human cells and promotes anchorage-independent growth in hTERT-transduced normal human cells.
Miyanaga A, Matsumoto M, Beck JA, Horikawa I, Oike T, Okayama H, Tanaka H, Burkett SS, Robles AI, Khan M, Lissa D, Seike M, Gemma A, Mano H, Harris CC
BMC cancer 21 ( 1 ) 310 2021年3月
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Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer.
Kobayashi Y, Kumamoto K, Okayama H, Matsumoto T, Nakano H, Saito K, Matsumoto Y, Endo E, Kanke Y, Watanabe Y, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Takenoshita S, Kono K
PloS one 16 ( 2 ) e0247169 2021年2月
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ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation.
Kase K, Saito M, Nakajima S, Takayanagi D, Saito K, Yamada L, Ashizawa M, Nakano H, Hanayama H, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Shiraishi K, Kohno T, Kono K
Carcinogenesis 42 ( 1 ) 21 - 30 2021年2月( ISSN:0143-3334 )
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Therapeutic potential of anti-VEGF receptor 2 therapy targeting for M2-tumor-associated macrophages in colorectal cancer.
Min AKT, Mimura K, Nakajima S, Okayama H, Saito K, Sakamoto W, Fujita S, Endo H, Saito M, Saze Z, Momma T, Ohki S, Kono K
Cancer immunology, immunotherapy : CII 70 ( 2 ) 289 - 298 2021年2月( ISSN:0340-7004 )
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PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms.
Nakano H, Saito M, Nakajima S, Saito K, Nakayama Y, Kase K, Yamada L, Kanke Y, Hanayama H, Onozawa H, Okayama H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Goto A, Kono K
Scientific reports 11 ( 1 ) 1982 - 1982 2021年1月
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Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer.
Leo Yamada, Motonobu Saito, Aung Kyi Thar Min, Katsuharu Saito, Mai Ashizawa, Koji Kase, Shotaro Nakajima, Hisashi Onozawa, Hirokazu Okayama, Hisahito Endo, Shotaro Fujita, Wataru Sakamoto, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Shinji Ohki, Koji Kono
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 1 ) 60 - 71 2021年1月( ISSN:1436-3291 )
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ハイブリッドアプローチで切除し得た骨盤内脂肪肉腫の1例
藤田正太郎, 門馬智之, 仲野宏, 山内直人, 山田玲央, 松本拓朗, 菅家康之, 花山寛之, 渡辺洋平, 小野澤寿志, 岡山洋和, 坂本渉, 齋藤元伸, 佐瀬善一郎, 河野浩二
癌と化学療法 47 ( 13 ) 1869 - 1871 2020年12月
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[A Case of Pelvic Liposarcoma Resected by Hybrid Approach].
Fujita S, Momma T, Nakano H, Yamauchi N, Yamada L, Matsumoto T, Kanke Y, Hanayama H, Watanabe Y, Onozawa H, Okayama H, Sakamoto W, Saito M, Saze Z, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 47 ( 13 ) 1869 - 1871 2020年12月( ISSN:0385-0684 )
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Tn Antigen Expression Defines an Immune Cold Subset of Mismatch-Repair Deficient Colorectal Cancer.
Matsumoto T, Okayama H, Nakajima S, Saito K, Nakano H, Endo E, Kase K, Ito M, Yamauchi N, Yamada L, Kanke Y, Onozawa H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
International journal of molecular sciences 21 ( 23 ) 9081 - 9081 2020年11月
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A TGFβ-dependent stromal subset underlies immune checkpoint inhibitor efficacy in DNA mismatch repair-deficient/microsatellite instability-high colorectal cancer.
Eisei Endo, Hirokazu Okayama, Katsuharu Saito, Shotaro Nakajima, Leo Yamada, Daisuke Ujiie, Koji Kase, Shotaro Fujita, Hisahito Endo, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Shinji Ohki, Kosaku Mimura, Koji Kono
Molecular cancer research : MCR 18 ( 9 ) 1402 - 1413 2020年9月( ISSN:1541-7786 )
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KRT17 as a prognostic biomarker for stage II colorectal cancer.
Ujiie D, Okayama H, Saito K, Ashizawa M, Thar Min AK, Endo E, Kase K, Yamada L, Kikuchi T, Hanayama H, Fujita S, Sakamoto W, Endo H, Saito M, Mimura K, Saze Z, Momma T, Ohki S, Kono K
Carcinogenesis 41 ( 5 ) 591 - 599 2020年7月( ISSN:0143-3334 )
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Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.
Yuko Nakayama, Kosaku Mimura, Ley-Fang Kua, Hirokazu Okayama, Aung Kyi Thar Min, Katsuharu Saito, Hiroyuki Hanayama, Yohei Watanabe, Motonobu Saito, Tomoyuki Momma, Zenichiro Saze, Shinji Ohki, Yoshiyuki Suzuki, Daisuke Ichikawa, Wei-Peng Yong, Koji Kono
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 6 ) 961 - 973 2020年5月( ISSN:1436-3291 )
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Higher modified Glasgow Prognostic Score and multiple stapler firings for rectal transection are risk factors for anastomotic leakage after low anterior resection in rectal cancer.
Wataru Sakamoto, Shinji Ohki, Tomohiro Kikuchi, Hirokazu Okayama, Shotaro Fujita, Hisahito Endo, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Koji Kono
Fukushima journal of medical science 66 ( 1 ) 10 - 16 2020年4月( ISSN:0016-2590 )
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Characterization of tumor-infiltrating immune cells in relation to microbiota in colorectal cancers.
Kikuchi T, Mimura K, Ashizawa M, Okayama H, Endo E, Saito K, Sakamoto W, Fujita S, Endo H, Saito M, Momma T, Saze Z, Ohki S, Shimada K, Yoshimura K, Tsunoda T, Kono K
Cancer immunology, immunotherapy : CII 69 ( 1 ) 23 - 32 2020年1月( ISSN:0340-7004 )
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Tuberculous peritonitis; The effectiveness of diagnostic laparoscopy and the perioperative infectious prevention: A case report.
Yamada L, Saito M, Aita T, Min A, Endo E, Kase K, Ujiie D, Hanayama H, Okayama H, Sakamoto W, Endo H, Fujita S, Saze Z, Momma T, Ohki S, Hamaguchi S, Kono K
International journal of surgery case reports 72 326 - 329 2020年
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A subset of patients with MSS/MSI-low-colorectal cancer showed increased CD8(+) TILs together with up-regulated IFN-γ.
Kikuchi T, Mimura K, Okayama H, Nakayama Y, Saito K, Yamada L, Endo E, Sakamoto W, Fujita S, Endo H, Saito M, Momma T, Saze Z, Ohki S, Kono K
Oncology letters 18 ( 6 ) 5977 - 5985 2019年12月( ISSN:1792-1074 )
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直腸癌術後の直腸膣瘻に対し、エストリオール膣錠と膣洗浄にて治癒した1例
藤田正太郎, 門馬智之, 佐藤孝洋, 遠藤英成, 加瀬晃志, 氏家大輔, 菊池智宏, 楡井東, 花山寛之, 渡辺洋平, 岡山洋和, 坂本渉, 遠藤久仁, 齋藤元伸, 佐瀬善一郎, 大木進司, 河野浩二.
癌と化学療法 46 ( 13 ) 2078 - 2080 2019年12月
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[A Case of Rectovaginal Fistula after Rectal Cancer Surgery Cured with Estriol Vaginal Tablet and Vaginal Lavage].
Fujita S, Momma T, Endo E, Kase K, Ujiie D, Hanayama H, Watanabe Y, Okayama H, Sakamoto W, Endo H, Saito M, Saze Z, Ohki S, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 46 ( 13 ) 2078 - 2080 2019年12月( ISSN:0385-0684 )
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Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis.
Okano M, Oshi M, Butash AL, Katsuta E, Tachibana K, Saito K, Okayama H, Peng X, Yan L, Kono K, Ohtake T, Takabe K
International journal of molecular sciences 20 ( 17 ) 4197 - 4197 2019年8月
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Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.
Nakayama Y, Mimura K, Tamaki T, Shiraishi K, Kua LF, Koh V, Ohmori M, Kimura A, Inoue S, Okayama H, Suzuki Y, Nakazawa T, Ichikawa D, Kono K
International journal of oncology 54 ( 6 ) 2030 - 2038 2019年6月( ISSN:1019-6439 )
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miRNA-148a-3p Regulates Immunosuppression in DNA Mismatch Repair-Deficient Colorectal Cancer by Targeting PD-L1.
Ashizawa M, Okayama H, Ishigame T, Thar Min AK, Saito K, Ujiie D, Murakami Y, Kikuchi T, Nakayama Y, Noda M, Tada T, Endo H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Ohki S, Mimura K, Kono K
Molecular cancer research : MCR 17 ( 6 ) 1403 - 1413 2019年6月( ISSN:1541-7786 )
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Prognostic role of ARID1A negative expression in gastric cancer.
Ashizawa M, Saito M, Min AKT, Ujiie D, Saito K, Sato T, Kikuchi T, Okayama H, Fujita S, Endo H, Sakamoto W, Momma T, Ohki S, Goto A, Kono K
Scientific reports 9 ( 1 ) 6769 2019年5月
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Explore the correlation between ARID1A and ANXA1 expressions in gastric cancer.
Yamada L, Saito M, Min A, Saito K, Kase K, Onozawa H, Okayama H, Fujita S, Endo H, Sakamoto W, Saze Z, Momma T, Ohki S, Mimura K, Kono K
Annals of Cancer Research and Therapy 27 ( 2 ) 46 - 51 2019年1月( ISSN:13446835 )
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Microanatomy of inferior mesenteric artery sheath in colorectal cancer surgery.
Sakamoto W, Yamada L, Suzuki O, Kikuchi T, Okayama H, Endo H, Fujita S, Saito M, Momma T, Saze Z, Ohki S, Kono K
Journal of the anus, rectum and colon 3 ( 4 ) 167 - 174 2019年
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A Case of Esophageal Cancer with Cervical Lymph Node Recurrence Six Years after Complete Response to Definitive Chemoradiotherapy
Fujita S, Ohki S, Hayase S, Ujiie D, Kikuchi T, Tada T, Hanayama H, Okayama H, Sakamoto W, Endo H, Saito M, Gonda K, Saze Z, Momma T, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1821 - 1823 2018年12月( ISSN:0385-0684 )
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根治的化学放射線療法で完全寛解した6年後に頸部リンパ節再発した食道癌の1例
藤田 正太郎, 大木 進司, 早瀬 傑, 氏家 大輔, 菊池 智弘, 多田 武志, 花山 寛之, 岡山 洋和, 坂本 渉, 遠藤 久仁, 斎藤 元伸, 権田 憲士, 佐瀬 善一郎, 門馬 智之, 河野 浩二
癌と化学療法 45 ( 13 ) 1821 - 1823 2018年12月( ISSN:0385-0684 )
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HALSで修復した絞扼を伴う成人Bochdalek孔ヘルニア小腸嵌頓の1例
氏家大輔, 小野澤寿志, 遠藤英成, 千田峻, 渡辺洋平, 岡山洋和, 齋藤勝, 門馬智之, 佐瀬善一郎, 大木進司, 金澤匡司, 河野浩二
福島医学雑誌 68 ( 3 ) 173 - 176 2018年12月( ISSN:0016-2582 )
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Aberrant glycosylation in colorectal cancer with genomic and epigenomic alterations.
Okayama H, Noda M, Kono K
Oncotarget 9 ( 86 ) 35609 - 35610 2018年11月
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A case of rectal colon cancer with paraneoplastic cerebellar degeneration
Gonda K, Kikuchi T, Shibata M, Hatakeyama Y, Tachiya Y, Rokkaku Y, Endo H, Fujita S, Sakamoto W, Hayase S, Okayama H, Hanayama H, Tada T, Nirei A, Ujiie D, Yamada R, Saze Z, Momma T, Ohki S, Kono K
Japanese Journal of Cancer and Chemotherapy 45 ( 10 ) 1510 - 1512 2018年10月( ISSN:0385-0684 )
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Glycosyltransferase gene expression identifies a poor prognostic colorectal cancer subtype associated with mismatch repair deficiency and incomplete glycan synthesis.
Noda M, Okayama H, Tachibana K, Sakamoto W, Saito K, Thar Min AK, Ashizawa M, Nakajima T, Aoto K, Momma T, Katakura K, Ohki S, Kono K
Clinical cancer research : an official journal of the American Association for Cancer Research 24 ( 18 ) 4468 - 4481 2018年9月( ISSN:1078-0432 )
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Prognostic impact of preoperative lymphocyte-to-monocyte ratio in patients with colorectal cancer with special reference to myeloid-derived suppressor cells.
Shimura T, Shibata M, Gonda K, Hayase S, Sakamoto W, Okayama H, Fujita S, Saito M, Momma T, Ohki S, Kono K
Fukushima journal of medical science 64 ( 2 ) 64 - 72 2018年8月( ISSN:0016-2590 )
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Serum transthyretin level is associated with prognosis of patients with gastric cancer.
Shimura T, Shibata M, Gonda K, Okayama H, Saito M, Momma T, Ohki S, Kono K
Journal of Surgical Research 227 145 - 150 2018年7月( ISSN:0022-4804 )
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Thar Min AK, Okayama H, Saito M, Ashizawa M, Aoto K, Nakajima T, Saito K, Hayase S, Sakamoto W, Tada T, Hanayama H, Saze Z, Momma T, Ohki S, Sato Y, Motoyama S, Mimura K, Kono K
Cancer medicine 2018年5月
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Thar Min AK, Okayama H, Saito M, Ashizawa M, Aoto K, Nakajima T, Saito K, Hayase S, Sakamoto W, Tada T, Hanayama H, Saze Z, Momma T, Ohki S, Sato Y, Motoyama S, Mimura K, Kono K
Cancer medicine 7 ( 7 ) 3321 - 3330 2018年5月
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Nakajima T, Okayama H, Ashizawa M, Noda M, Aoto K, Saito M, Monma T, Ohki S, Shibata M, Takenoshita S, Kono K
Oncology letters 15 ( 2 ) 2604 - 2610 2018年2月( ISSN:1792-1074 )
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Annexin A1 is upregulated in p53-positive gastric cancer
Saito M, Saito K, Nakano H, Kikuchi T, Okayama H, Fujita S, Endo H, Sakamoto W, Momma T, Ohki S, Kono K
Annals of Cancer Research and Therapy 26 ( 1 ) 26 - 30 2018年1月( ISSN:13446835 )
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Mimura K, Teh JL, Okayama H, Shiraishi K, Kua LF, Koh V, Smoot DT, Ashktorab H, Oike T, Suzuki Y, Fazreen Z, Asuncion BR, Shabbir A, Yong WP, So J, Soong R, Kono K
109 ( 1 ) 43 - 53 2018年1月( ISSN:1347-9032 )
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Aoto K, Mimura K, Okayama H, Saito M, Chida S, Noda M, Nakajima T, Saito K, Abe N, Ohki S, Ohtake T, Takenoshita S, Kono K
Oncology reports 39 ( 1 ) 151 - 159 2018年1月( ISSN:1021-335X )
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Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer.
Noda M, Okayama H, Kofunato Y, Chida S, Saito K, Tada T, Ashizawa M, Nakajima T, Aoto K, Kikuchi T, Sakamoto W, Endo H, Fujita S, Saito M, Momma T, Ohki S, Kono K
PloS one 13 ( 7 ) e0200315 2018年
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Hayase S, Kumamoto K, Saito K, Kofunato Y, Sato Y, Okayama H, Miyamoto K, Ohki S, Takenoshita S
Oncology letters 14 ( 6 ) 7410 - 7416 2017年12月( ISSN:1792-1074 )
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CDX2 is involved in microRNA-associated inflammatory carcinogenesis in gastric cancer.
Saito M, Okayama H, Saito K, Ando J, Kumamoto K, Nakamura I, Ohki S, Ishi Y, Takenoshita S
Oncology letters 14 ( 5 ) 6184 - 6190 2017年11月( ISSN:1792-1074 )
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Expression of circadian clock genes in human colorectal adenoma and carcinoma.
Momma T, Okayama H, Saitou M, Sugeno H, Yoshimoto N, Takebayashi Y, Ohki S, Takenoshita S
Oncology letters 14 ( 5 ) 5319 - 5325 2017年11月( ISSN:1792-1074 )
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ミスマッチ修復機構欠損を有する大腸癌におけるMicroRNAによるPD-L1制御機構
芦澤 舞, 岡山 洋和, Aung Kyi Thar Min, 野田 勝, 青砥 慶太, 中島 隆宏, 石亀 輝英, 三村 耕作, 河野 浩二
癌と化学療法 44 ( 10 ) 889 - 891 2017年10月( ISSN:0385-0684 )
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[Regulation of PD-L1 by MicroRNA in Mismatch Repair Deficient-Colorectal Cancer].
Ashizawa M, Okayama H, Aung Kyi Thar Min, Noda M, Aoto K, Nakajima T, Ishigame T, Mimura K, Kono K
Gan to kagaku ryoho. Cancer & chemotherapy 44 ( 10 ) 889 - 891 2017年10月( ISSN:0385-0684 )
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デヴィータがんの分子生物学 第2版
岡山洋和, 河野浩二, 竹之下誠一(翻訳)
メディカルサイエンスインターナショナル 19 2017年6月
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Kono K, Yong WP, Okayama H, Shabbir A, Momma T, Ohki S, Takenoshita S, So J
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20 ( Suppl 1 ) 122 - 127 2017年3月( ISSN:1436-3291 )
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Minamikawa K., Shibata M., Gonda K., Ujiie D., Ashizawa M., Nakajima T., Okayama H., Sakamoto W., Saito M., Momma T., Mimura K., Ohki S., Shimura T., Ohto H., Takenoshita S., Kono K.
Annals of Cancer Research and Therapy 25 ( 2 ) 67 - 76 2017年1月( ISSN:13446835 )
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Chida S, Okayama H, Noda M, Saito K, Nakajima T, Aoto K, Hayase S, Momma T, Ohki S, Kono K, Takenoshita S
Carcinogenesis 37 ( 9 ) 878 - 887 2016年9月( ISSN:0143-3334 )
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神経内分泌癌成分と腺癌成分が同時にリンパ節転移を来した食道胃接合部神経内分泌癌の1例
中島 隆宏, 山内 直人, 月田 茂之, 千田 峻, 野田 勝, 岡山 洋和, 早瀬 傑, 藤田 正太郎, 門馬 智之, 高和 正, 大木 進司, 志村 龍男, 河野 浩二, 大竹 徹, 鈴木 理, 竹之下 誠一
福島医学雑誌 66 ( 1 ) 18 - 23 2016年3月( ISSN:0016-2582 )
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Stage IV胃癌に対する化学療法後、手術に移行できた1例
藤田 正太郎, 門馬 智之, 大木 進司, 村上 祐子, 岡山 洋和, 矢澤 貴, 高和 正, 隈元 謙介, 大竹 徹, 河野 浩二, 竹之下 誠一
癌と化学療法 42 ( 12 ) 1668 - 1670 2015年11月( ISSN:0385-0684 )
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Shotaro Fujita, Tomoyuki Monma, Shinji Ohki, Yuko Murakami, Hirokazu Okayama, Takashi Yazawa, Masashi Takawa, Kensuke Kumamoto, Toru Ohtake, Koji Kono, Seiichi Takenoshita
Gan to kagaku ryoho. Cancer & chemotherapy 42 ( 12 ) 1668 - 70 2015年11月( ISSN:0385-0684 )
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An integrated prognostic classifier for stage I lung adenocarcinoma based on mRNA, microRNA and DNA methylation biomarkers
Robles AI, Kanai Y, Mathé E, Okayama H, Schetter AJ, Brown D, Petersen D, Bowman E, Noro R, Welsh J, Edelman D, Stevenson H, Tsuchiya N, Kohno T, Skaug V, Mollerup S, Haugen A, Meltzer P, Yokota J, Harris CC.
J Thorac Oncol 10 ( 7 ) 1037 - 1048 2015年6月
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Increased MicroRNA-34b and -34c Predominantly Expressed in Stromal Tissues Is Associated with Poor Prognosis in Human Colon Cancer
Hiyoshi Y, Schetter AJ, Okayama H, Inamura K, Anami K, Nguyen GH, Horikawa I, Hawkes JE, Bowman ED, Leung SY, Harris CC.
PLoS One 10 ( 4 ) e0124899 2015年4月
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Identification of a functional SNP in the 3'UTR of CXCR2 that is associated with reduced risk of lung cancer
Ryan BM, Robles AI, McClary AC, Haznadar M, Bowman ED, Pine SR, Brown D, Khan M, Shiraishi K, Kohno T, Okayama H, Modali R, Yokota J, Harris CC.
Cancer Res 75 ( 3 ) 566 - 575 2015年2月
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Okayama H, Schetter AJ, Ishigame T, Robles AI, Kohno T, Yokota J, Takenoshita S, Harris CC
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 23 ( 12 ) 2884 - 94 2014年12月( ISSN:1055-9965 )
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連載医学用語解説 炎症性大腸癌発癌過程における機能獲得型(gain-of-function)p53変異
岡山 洋和, 竹之下 誠一
G.I.Research 22 ( 5 ) 473 - 474 2014年10月( ISSN:0918-9408 )
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連載医学用語解説 大腸癌バイオマーカーとしてのマイクロRNA、miR-21
岡山 洋和, 竹之下 誠一
G.I.Research 22 ( 5 ) 471 - 472 2014年10月( ISSN:0918-9408 )
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Druggable oncogene fusions in invasive mucinous lung adenocarcinoma
Nakaoku T, Tsuta K, Ichikawa H, Shiraishi K, Sakamoto H, Enari M, Furuta K, Shimada Y, Ogiwara H, Watanabe S, Nokihara H, Yasuda K, Hiramoto M, Nammo T, Ishigame T, Schetter AJ, Okayama H, Harris CC, Kim YH, Mishima M, Yokota J, Yoshida T, Kohno T.
Clin Cancer Res 20 ( 12 ) 3087 - 93 2014年6月
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TSPAN2 is involved in cell invasion and motility during lung cancer progression
Otsubo C, Otomo R, Miyazaki M, Matsushima-Hibiya Y, Kohno T, Iwakawa R, Takeshita F, Okayama H, Ichikawa H, Saya H, Kiyono T, Ochiya T, Tashiro F, Nakagama H, Yokota J, Enari M.
Cell Rep 7 ( 2 ) 527 - 38 2014年4月
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High miR-21 expression from FFPE tissues is associated with poor survival and response to adjuvant chemotherapy in colon cancer
Oue N, Anami K, Schetter AJ, Moehler M, Okayama H, Khan MA, Bowman ED, Mueller A, Schad A, Shimomura M, Hinoi T, Aoyagi K, Sasaki H, Okajima M, Ohdan H, Galle PR, Yasui W, Harris CC.
Int J Cancer 134 ( 8 ) 1926 - 34 2014年4月
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Naohide Oue, Katsuhiro Anami, Aaron J. Schetter, Markus Moehler, Hirokazu Okayama, Mohammed A. Khan, Elise D. Bowman, Annett Mueller, Arno Schad, Manabu Shimomura, Takao Hinoi, Kazuhiko Aoyagi, Hiroki Sasaki, Masazumi Okajima, Hideki Ohdan, Peter R. Galle, Wataru Yasui, Curtis C. Harris
INTERNATIONAL JOURNAL OF CANCER 134 ( 8 ) 1926 - 1934 2014年4月( ISSN:0020-7136 )
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Possible involvement of LKB1-AMPK signaling in non-homologous end joining
Ui A, Ogiwara H, Nakajima S, Kanno S, Watanabe R, Harata M, Okayama H, Harris CC, Yokota J, Yasui A, Kohno T.
Oncogene 33 ( 13 ) 1640 - 8 2014年3月
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Akagi I., Okayama H., Schetter A., Robles A., Kohno T., Bowman E., Kazandjian D., Welsh J., Oue N., Saito M., Miyashita M., Uchida E., Takizawa T., Takenoshita S., Skaug V., Mollerup S., Haugen A., Yokota J., Harris C.
Cancer Research 73 ( 13 ) 3821 - 3832 2013年7月( ISSN:00085472 )
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NOS2 enhances KRAS-induced lung carcinogenesis, inflammation and microRNA-21 expression
Okayama H., Saito M., Oue N., Weiss J., Stauffer J., Takenoshita S., Wiltrout R., Hussain S., Harris C.
International Journal of Cancer 132 ( 1 ) 9 - 18 2013年1月( ISSN:00207136 )
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UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer
Kofunato Y, Kumamoto K, Saitou K, Hayase S, Okayama H, Miyamoto K, Sato Y, Katakura K, Nakamura I, Ohki S, Koyama Y, Unoki M, Takenoshita S.
Oncol Rep 28 ( 6 ) 1997 - 2002 2012年12月
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UHRF1 expression is upregulated and associated with cellular proliferation in colorectal cancer.
Kofunato Y, Kumamoto K, Saitou K, Hayase S, Okayama H, Miyamoto K, Sato Y, Katakura K, Nakamura I, Ohki S, Koyama Y, Unoki M, Takenoshita S
Oncology reports 28 ( 6 ) 1997 - 2002 2012年12月( ISSN:1021-335X )
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Contribution of germline mutations to PARK2 gene inactivation in lung adenocarcinoma
Iwakawa R, Okayama H, Kohno T, Sato-Otsubo A, Ogawa S, Yokota J.
Genes Chromosomes Cancer 51 ( 5 ) 462 - 72 2012年5月
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KIF5B-RET fusions in lung adenocarcinoma
Kohno T, Ichikawa H, Totoki Y, Yasuda K, Hiramoto M, Nammo T, Sakamoto H, Tsuta K, Furuta K, Shimada Y, Iwakawa R, Ogiwara H, Oike T, Enari M, Schetter AJ, Okayama H, Haugen A, Skaug V, Chiku S, Yamanaka I, Arai Y, Watanabe S, Sekine I, Ogawa S, Harris CC, Tsuda H, Yoshida T, Yokota J, Shibata T.
Nat Med 18 ( 3 ) 375 - 7 2012年2月
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Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas
Okayama H, Kohno T, Ishii Y, Shimada Y, Shiraishi K, Iwakawa R, Furuta K, Tsuta K, Shibata T, Yamamoto S, Watanabe S, Sakamoto H, Kumamoto K, Takenoshita S, Gotoh N, Mizuno H, Sarai A, Kawano S, Yamaguchi R, Miyano S, Yokota J.
Cancer Res 72 ( 1 ) 100 - 11 2012年1月
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The role of microRNAs in colorectal cancer
Schetter AJ, Okayama H, Harris CC.
Cancer J 18 ( 3 ) 244 - 52 2012年
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MicroRNAs and inflammation in the pathogenesis and progression of colon cancer
Okayama H, Schetter AJ, Harris CC.
Dig Dis 2012年
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Ectopic expression of MECA-79 as a novel prognostic indicator in gastric cancer
Okayama H, Kumamoto K, Saitou K, Hayase S, Kofunato Y, Sato Y, Miyamoto K, Nakamura I, Ohki S, Koyama Y, Ishii Y, Takenoshita S.
Cancer Sci 102 ( 5 ) 1088 - 94 2011年5月
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Up-regulated Annexin A1 expression in gastrointestinal cancer is associated with cancer invasion and lymph node metastasis
Sato Y, Kumamoto K, Saito K, Okayama H, Hayase S, Kofunato Y, Miyamoto K, Nakamura I, Ohki S, Koyama Y, Takenoshita S.
Exp Ther Med 2 ( 2 ) 239 - 243 2011年3月
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Overexpression of endoglin (CD105) is associated with recurrence in radically resected gastric cancer
Koyama Y, Okayama H, Kumamoto K, Saito K, Nakamura I, Ohki S, Takenoshita S.
Exp Ther Med 1 ( 4 ) 627 - 633 2010年6月
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CD44v6, MMP-7 and nuclear Cdx2 are significant biomarkers for prediction of lymph node metastasis in primary gastric cancer
Okayama H, Kumamoto K, Saitou K, Hayase S, Kofunato Y, Sato Y, Miyamoto K, Nakamura I, Ohki S, Sekikawa K, Takenoshita S.
Oncol Rep 22 ( 4 ) 745 - 55 2009年10月