Faculty Profiles - SHIO Yutaka

Papers - SHIO Yutaka

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Cardiovascular safety of pimitespib in patients with advanced solid tumors: An open-label, nonrandomized, phase 1 study.

Naoki K, Igawa S, Uojima H, Tsumura H, Sengoku N, Karayama M, Shimomura A, Ohtake T, Shio Y, Hosokawa A, Komatsu Y, Kumagai Y.

Cancer 130 ( 21 ) 3745 - 3756 2024.11（ ISSN:0008543X ）

Neoadjuvant nivolumab plus chemotherapy in resectable non-small-cell lung cancer in Japanese patients from CheckMate 816. International coauthorship

Mitsudomi T, Ito H, Okada M, Sugawara S, Shio Y, Tomii K, Okami J, Sakakura N, Kubota K, Takamochi K, Atagi S, Tsuboi M, Oizumi S, Ikeda N, Ohde Y, Ntambwe I, Mahmood J, Cai J, Tanaka F.

Cancer Science 115 ( 2 ) 540 - 554 2024.2（ ISSN:13479032 ）

小細胞肺癌に対する化学療法成績と長期無増悪生存の三例の報告

大浦光章, 山浦匠, 峯勇人, 穴沢予識, 塩豊

竹田綜合病院医学雑誌 49 1 - 8 2023.12（ ISSN:13470183 ）

縦隔原発胚細胞腫瘍と小細胞肺癌が併存した1例

山浦匠, 峯勇人, 佐藤弘隆, 山口佳子, 塩豊, 鈴木弘行

竹田綜合病院医学雑誌 49 23 - 28 2023.12（ ISSN:13470183 ）

A case of discordant histology and expression of programmed death ligand 1 between primary tumor and brain metastases in adenosquamous carcinoma of the lung

Takagi H, Muto S, Enta A, Fukuhara M, Asano S, Shio Y, Suzuki H.

Thoracic Cancer 14 ( 26 ) 2707 - 2711 2023.9（ ISSN:17597706 ）

Traumatic Hemomediastinum and Hemothorax in a Patient With Totally Corrected Tetralogy of Fallot

Matsumura Y, Inomata S, Yamaguchi H, Watanabe M, Ozaki Y, Muto S, Okabe N, Shio Y, Tsukada Y, Suzuki H.

Annals of Thoracic Surgery Short Reports 1 ( 1 ) 91 - 93 2023.3

Clinical Features of Endocrine Disorders with Immune Checkpoint Inhibitor in Patients with Non-Small Cell Lung Cancer

50 ( 2 ) 177 - 182 2023.2（ ISSN:03850684 ）

A case of schwannoma thought to be cervical lymph node metastasis on FDG-PET/CT sfter surgery for lung cancer

68 ( 1 ) 81 - 85 2023.1（ ISSN:00099252 ）

Wnt/β-Catenin Signaling and Resistance to Immune Checkpoint Inhibitors: From Non-Small-Cell Lung Cancer to Other Cancers

Muto S, Enta A, Maruya Y, Inomata S, Yamaguchi H, Mine H, Takagi H, Ozaki Y, Watanabe M, Inoue T, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Hamada K, Suzuki H.

Biomedicines 11 ( 1 ) 190 2023.1

Pulmonary large cell carcinoma, highly positive for PD-L1, shows marked response to pembrolizumab: A case report.

Okabe N, Mine H, Takagi H, Watanabe M, Muto S, Matsumura Y, Shio Y, Suzuki H

Thoracic cancer 12 ( 7 ) 1141 - 1144 2021.4（ ISSN:1759-7706 ）

Delta-like 1 homolog (DLK1) as a possible therapeutic target and its application to radioimmunotherapy using <sup>125</sup>I-labelled anti-DLK1 antibody in lung cancer models (HOT1801 and FIGHT004).

Takagi H, Zhao S, Muto S, Yokouchi H, Nishihara H, Harada T, Yamaguchi H, Mine H, Watanabe M, Ozaki Y, Inoue T, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Kanno R, Aoki M, Tan C, Shimoyama S, Yamazaki S, Kikuchi H, Sakakibara-Konishi J, Oizumi S, Harada M, Akie K, Sugaya F, Fujita Y, Takamura K, Kojima T, Honjo O, Minami Y, Nishimura M, Dosaka-Akita H, Nakamura K, Inano A, Isobe H, Suzuki H

Lung cancer (Amsterdam, Netherlands) 153 134 - 142 2021.3（ ISSN:0169-5002 ）

Tumor β-catenin expression is associated with immune evasion in non-small cell lung cancer with high tumor mutation burden.

Muto S, Ozaki Y, Yamaguchi H, Mine H, Takagi H, Watanabe M, Inoue T, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H

Oncology letters 21 ( 3 ) 203 2021.3（ ISSN:1792-1074 ）

Our experience of lung resection in patients who decline blood transfusion for religious reasons.

Takagi H, Muto S, Yamaguchi H, Mine H, Ozaki Y, Okabe N, Matsumura Y, Shio Y, Suzuki H

General thoracic and cardiovascular surgery 2021.2（ ISSN:1863-6705 ）

Diffuse Cystic Metastases in the Lung after Nivolumab Treatment in a Patient with Non-Small Cell Lung Cancer: A Case Report.

Muto S, Ozaki Y, Inoue T, Okabe N, Matsumura Y, Hasegawa T, Shio Y, Suzuki H

Case reports in oncology 14 ( 1 ) 34 - 38 2021.1

Monitoring tumor infiltrating lymphocytes by peripheral blood in lung cancer patients

Muto S., Yamaguchi H., Mine H., Takagi H., Ozaki Y., Watanabe M., Inoue T., Yamaura T., Fukuhara M., Okabe N., Matsumura Y., Hasegawa T., Osugi J., Hoshino M., Higuchi M., Shio Y., Suzuki H.

Japanese Journal of Cancer and Chemotherapy 47 ( 9 ) 1287 - 1291 2020.9（ ISSN:03850684 ）

[Monitoring Tumor Infiltrating Lymphocytes by Peripheral Blood in Lung Cancer Patients].

Muto S, Yamaguchi H, Mine H, Takagi H, Ozaki Y, Watanabe M, Inoue T, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Suzuki H

Gan to kagaku ryoho. Cancer & chemotherapy 47 ( 9 ) 1287 - 1291 2020.9（ ISSN:0385-0684 ）

Successful Treatment of Combined Large Cell Neuroendocrine Carcinoma Harboring an EGFR Mutation with <i>EGFR</i>-TKIs plus Bevacizumab: A Case Report.

Muto S, Ozaki Y, Okabe N, Matsumura Y, Hasegawa T, Shio Y, Hashimoto Y, Suzuki H

Case reports in oncology 13 ( 3 ) 1387 - 1392 2020.9

【がん免疫療法のバイオマーカー探索】肺癌における腫瘍浸潤リンパ球の末梢血によるモニタリング

武藤哲史, 山口光, 峯勇人, 高木玄教, 尾崎有紀, 渡部晶之, 井上卓哉, 山浦匠, 福原光朗, 岡部直行, 松村勇輝, 長谷川剛生, 大杉純, 星野実加, 樋口光徳, 塩豊, 鈴木弘行

癌と化学療法 47 ( 9 ) 1287 - 1291 2020.9（ ISSN:0385-0684 ）

Monitoring Tumor Infiltrating Lymphocytes by Peripheral Blood in Lung Cancer Patients.

Satoshi Muto, Hikaru Yamaguchi, Hayato Mine, Hironori Takagi, Yuki Ozaki, Masayuki Watanabe, Takuya Inoue, Takumi Yamaura, Mitsuro Fukuhara, Naoyuki Okabe, Yuki Matsumura, Takeo Hasegawa, Jun Osugi, Mika Hoshino, Mitsunori Higuchi, Yutaka Shio, Hiroyuki Suzuki

Japanese Journal of Cancer and Chemotherapy 47 ( 9 ) 1287 - 1291 2020.9（ ISSN:03850684 ）

Genetic alterations in epidermal growth factor receptor-tyrosine kinase inhibitor-naïve non-small cell lung carcinoma.

Yamaura T, Muto S, Mine H, Takagi H, Watanabe M, Ozaki Y, Inoue T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Suzuki H

Oncology letters 19 ( 6 ) 4169 - 4176 2020.6（ ISSN:1792-1074 ）

Tumor mutation burden and immunological, genomic, and clinicopathological factors as biomarkers for checkpoint inhibitor treatment of patients with non-small-cell lung cancer.

Ozaki Y, Muto S, Takagi H, Watanabe M, Inoue T, Fukuhara M, Yamaura T, Okabe N, Matsumura Y, Hasegawa T, Ohsugi J, Hoshino M, Shio Y, Tanaka D, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H

Cancer immunology, immunotherapy : CII 69 ( 1 ) 127 - 134 2020.1（ ISSN:0340-7004 ）

Hasegawa T, Ozaki Y, Inoue T, Watanabe Y, Fukuhara M, Yamaura T, Muto S, Okabe N, Higuchi M, Shio Y, Suzuki H

Journal of medical case reports 13 ( 1 ) 316 2019.10

Prognostic impact of serum transthyretin in patients with non-small cell lung cancer.

Shimura T, Shibata M, Inoue T, Owada-Ozaki Y, Yamaura T, Muto S, Hasegawa T, Shio Y, Suzuki H

Molecular and clinical oncology 10 ( 6 ) 597 - 604 2019.6（ ISSN:2049-9450 ）

Thoracoscopic Right Upper Lobectomy for Lung Cancer with a Displaced Right B1+3 Bronchus.

Satoshi Muto, Yuki Ozaki, Takuya Inoue, Takumi Yamaura, Mitsuro Fukuhara, Naoyuki Okabe, Takeo Hasegawa, Yutaka Shio, Hiroyuki Suzuki

The Journal of the Japan Society for Respiratory Endoscopy 41 ( 3 ) 293 - 297 2019.5（ ISSN:02872137 ）

右B1+3転位気管支を伴う右上葉肺癌に対して胸腔鏡下肺葉切除術を行った1例

武藤哲史, 尾崎有紀, 井上卓哉, 山浦匠, 福原光朗, 岡部直行, 長谷川剛生, 塩豊, 鈴木弘行

気管支学 41 ( 3 ) 293 - 297 2019.5（ ISSN:0287-2137 ）

直腸癌の縦隔リンパ節転移により急性壊死性縦隔炎をきたした1例

武藤哲史, 岡部直行, 長谷川剛生, 塩豊, 鈴木弘行

日本呼吸器外科学会雑誌 32 ( 7 ) 881 - 886 2018.11（ ISSN:0919-0945 ）

Prognostic Impact of Tumor Mutation Burden in Patients With Completely Resected Non-Small Cell Lung Cancer: Brief Report.

Owada-Ozaki Y, Muto S, Takagi H, Inoue T, Watanabe Y, Fukuhara M, Yamaura T, Okabe N, Matsumura Y, Hasegawa T, Ohsugi J, Hoshino M, Shio Y, Nanamiya H, Imai JI, Isogai T, Watanabe S, Suzuki H

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 13 ( 8 ) 1217 - 1221 2018.8（ ISSN:1556-0864 ）

Comparison of surgical outcomes after pneumonectomy and pulmonary function-preserving surgery for non-small cell lung cancer.

Higuchi M, Takagi H, Ozaki Y, Inoue T, Watanabe Y, Yamaura T, Fukuhara M, Muto S, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Shio Y, Suzuki H

Fukushima journal of medical science 64 ( 1 ) 30 - 37 2018.4（ ISSN:0016-2590 ）

Comparison of surgical outcomes after pneumonectomy and pulmonary function-preserving surgery for non-small cell lung cancer(和訳中)

Higuchi Mitsunori, Takagi Hironori, Ozaki Yuki, Inoue Takuya, Watanabe Yuzuru, Yamaura Takumi, Fukuhara Mitsuro, Muto Satoshi, Okabe Naoyuki, Matsumura Yuki, Hasegawa Takeo, Osugi Jun, Hoshino Mika, Shio Yutaka, Suzuki Hiroyuki

Fukushima Journal of Medical Science 64 ( 1 ) 30 - 37 2018.4（ ISSN:0016-2590 ）

Family with sequence similarity 83, member B is a predictor of poor prognosis and a potential therapeutic target for lung adenocarcinoma expressing wild-type epidermal growth factor receptor.

Yamaura T, Ezaki J, Okabe N, Takagi H, Ozaki Y, Inoue T, Watanabe Y, Fukuhara M, Muto S, Matsumura Y, Hasegawa T, Hoshino M, Osugi J, Shio Y, Waguri S, Tamura H, Imai JI, Ito E, Yanagisawa Y, Honma R, Watanabe S, Suzuki H.

Oncology letters 15 ( 2 ) 1549 - 1558 2018.2（ ISSN:1792-1074 ）

Acute necrotizing mediastinitis caused by rectal cancer metastasis

Muto Satoshi, Okabe Naoyuki, Hasegawa Takeo, Shio Yutaka, Suzuki Hiroyuki

The Journal of the Japanese Association for Chest Surgery 32 ( 7 ) 881 - 886 2018（ ISSN:0919-0945 ）

The efficacy of the Kampo medicine rikkunshito for chemotherapy-induced anorexia (RICH trial): study protocol for a randomized controlled trial.

Inoue T, Takagi H, Owada Y, Watanabe Y, Yamaura T, Fukuhara M, Muto S, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Yokouchi H, Kanazawa K, Ohbuchi K, Fukushima T, Munakata M, Suzuki H

Trials 18 ( 1 ) 485 2017.10

I. History of immunotherapy and cancer vaccine for lung cancer

Suzuki H., Takagi H., Owada Y., Watanabe Y., Inoue T., Fukuhara M., Yamaura T., Muto S., Okabe N., Hasegawa T., Shio Y.

Japanese Journal of Cancer and Chemotherapy 44 ( 8 ) 646 - 649 2017.8（ ISSN:03850684 ）

[I. History of Immunotherapy and Cancer Vaccine for Lung Cancer].

Suzuki H, Takagi H, Owada Y, Watanabe Y, Inoue T, Fukuhara M, Yamaura T, Muto S, Okabe N, Hasegawa T, Shio Y

Gan to kagaku ryoho. Cancer & chemotherapy 44 ( 8 ) 646 - 649 2017.8（ ISSN:0385-0684 ）

Thorax/Lung and Mediastinum, Pleura:Cancer　肺癌　肺癌免疫療法　新時代の幕開け　肺がんに対する免疫療法の歴史とがんワクチン療法

鈴木弘行, 高木玄教, 大和田有紀, 渡邊譲, 井上卓哉, 福原光朗, 山浦匠, 武藤哲史, 岡部直行, 長谷川剛生, 塩豊

癌と化学療法 44 ( 8 ) 646 - 649 2017.8（ ISSN:0385-0684 ）

Efficacy and tolerability of nanoparticle albumin-bound paclitaxel in combination with carboplatin as a late-phase chemotherapy for recurrent and advanced non-small-cell lung cancer: A multi-center study of the Fukushima lung cancer association group of surgeons.

Higuchi M, Takagi H, Owada Y, Inoue T, Watanabe Y, Yamaura T, Fukuhara M, Muto S, Okabe N, Matsumura Y, Hasegawa T, Yonechi A, Osugi J, Hoshino M, Shio Y, Fujiu K, Kanno R, Ohishi A, Suzuki H, Gotoh M

Oncology letters 13 ( 6 ) 4315 - 4321 2017.6（ ISSN:1792-1074 ）

Serum Nitric Oxide as a Predictive Biomarker for Bevacizumab in Non-small Cell Lung Cancer Patients.

Muto S, Takagi H, Owada Y, Inoue T, Watanabe Y, Yamaura T, Fukuhara M, Okabe N, Matsumura Y, Hasegawa T, Osugi J, Hoshino M, Higuchi M, Shio Y, Suzuki H

Anticancer research 37 ( 6 ) 3169 - 3174 2017.6（ ISSN:0250-7005 ）

Prognostic Impact of Hypoxia-Inducible miRNA-210 in Patients with Lung Adenocarcinoma.

Osugi J, Kimura Y, Owada Y, Inoue T, Watanabe Y, Yamaura T, Fukuhara M, Muto S, Okabe N, Matsumura Y, Hasegawa T, Yonechi A, Hoshino M, Higuchi M, Shio Y, Suzuki H, Gotoh M

Journal of oncology 2015 316745 2015（ ISSN:1687-8450 ）

ラブドイド形質を伴う肺大細胞癌の1手術例　本邦報告例の検討

大杉純, 長谷川剛生, 米地敦, 星野実加, 塩豊, 鈴木弘行

日本呼吸器外科学会雑誌 28 ( 7 ) 882 - 887 2014.11（ ISSN:0919-0945 ）

Two cases of thymic carcinoid treated with octreotide long-acting repeatable

Okabe N., Inoue T., Watanabe Y., Muto S., Hasegawa T., Ohsugi J., Higuchi M., Shio Y., Suzuki H.

Japanese Journal of Cancer and Chemotherapy 41 ( 7 ) 879 - 883 2014.7（ ISSN:03850684 ）

[Two cases of thymic carcinoid treated with octreotide long-acting repeatable].

Okabe N, Inoue T, Watanabe Y, Muto S, Hasegawa T, Ohsugi J, Higuchi M, Shio Y, Suzuki H

Gan to kagaku ryoho. Cancer & chemotherapy 41 ( 7 ) 879 - 83 2014.7（ ISSN:0385-0684 ）

胸腺カルチノイドに対してオクトレオチドLong Acting Repeatableを使用した2例

岡部直行, 井上卓哉, 渡邉譲, 武藤哲史, 長谷川剛生, 大杉純, 樋口光徳, 塩豊, 鈴木弘行

癌と化学療法 41 ( 7 ) 879 - 883 2014.7（ ISSN:0385-0684 ）

後腹膜腔へ進展した肺腺癌の1切除例

大和田有紀, 柳沼裕嗣, 長谷川剛生, 大杉純, 塩豊, 鈴木弘行

肺癌 54 ( 2 ) 57 - 62 2014.4（ ISSN:0386-9628 ）

A Case of Resected Pulmonary Adenocarcinoma Invading the Retroperitoneal Space

Owada Yuki, Yaginuma Hiroshi, Hasegawa Takeo, Ohsugi Jun, Shio Yutaka, Suzuki Hiroyuki

JJLC 54 ( 2 ) 57 - 62 2014.1（ ISSN:03869628 ）

Recent advances in immunotherapy for non-small-cell lung cancer.

Suzuki H, Owada Y, Watanabe Y, Inoue T, Fukuharav M, Yamaura T, Mutoh S, Okabe N, Yaginuma H, Hasegawa T, Yonechi A, Ohsugi J, Hoshino M, Higuchi M, Shio Y, Gotoh M

Human vaccines & immunotherapeutics 10 ( 2 ) 352 - 7 2014（ ISSN:2164-5515 ）

A case of thymic carcinoma in the posterior mediastinum from an ectopic thymus

Kushida Masao, Watanabe Junichiro, Shio Yutaka, Ohsugi Jun, Hasegawa Takeo, Suzuki Hiroyuki

The Journal of the Japanese Association for Chest Surgery 28 ( 1 ) 121 - 126 2014（ ISSN:0919-0945 ）

A case of large cell carcinoma of the lung with rhabdoid phenotype

Osugi Jun, Hasegawa Takeo, Yonechi Atushi, Hoshino Mika, Shio Yutaka, Suzuki Hiroyuki

The Journal of the Japanese Association for Chest Surgery 28 ( 7 ) 882 - 887 2014（ ISSN:0919-0945 ）

Multiple therapeutic peptide vaccines consisting of combined novel cancer testis antigens and anti-angiogenic peptides for patients with non-small cell lung cancer

Suzuki H., Fukuhara M., Yamaura T., Mutoh S., Okabe N., Yaginuma H., Hasegawa T., Yonechi A., Osugi J., Hoshino M., Kimura T., Higuchi M., Shio Y., Ise K., Takeda K., Gotoh M.

Journal of Translational Medicine 11 ( 1 ) 2013.4

WS-19-8 肺癌に対するプラチナ併用化学療法における制吐療法としての六君子湯の有用性(WS ワークショップ,第113回日本外科学会定期学術集会)

鈴木弘行, 大和田有紀, 渡邉譲, 福原光朗, 山浦匠, 武藤哲史, 岡部直行, 柳沼裕嗣, 長谷川剛生, 米地敦, 大杉純, 星野実加, 樋口光徳, 塩豊, 後藤満一

日本外科学会雑誌 114 ( 2 ) 2013.3（ ISSN:18801129 ）

PS-252-1 SmartMIMAS呼吸器外科利用のための必要機能に関する共同研究(PS ポスターセッション,第113回日本外科学会定期学術集会)

米地敦, 鈴木弘行, 塩豊, 樋口光徳, 星野実加, 大杉純, 長谷川剛生, 柳沼裕嗣, 岡部直行, 武藤哲史, 大和田有紀, 後藤満一

日本外科学会雑誌 114 ( 2 ) 2013.3（ ISSN:18801129 ）

特集／管理栄養士のためのベッドサイド栄養管理のはじめかた：末梢静脈栄養の実際、合併症とその対策．

塩　　豊*，武藤　淳．

Nutrition Care 2011年秋増刊 32 167 - 172 2011

特集／管理栄養士のためのベッドサイド栄養管理のはじめかた：中心静脈栄養の実際、合併症とその対策．

塩　　豊*，武藤　淳

Nutrition Care 2011年秋増刊 32 173 - 181 2011

原発不明癌に対する化学療法後に発症した非Ｈｏｄｇｋｉｎリンパ腫の1例．

藤生浩一，佐久間秀夫，塩　　豊*，鈴木弘行*，母里正敏．

癌と化学療法 35 ( 11 ) 1907 - 1909 2008

原発性肺癌外科治療成績の検討－福島赤十字病院に於ける－

大石明雄，岡部直行，塩　　豊*，樋口光徳*，長谷川剛生*，山田文彦*，土屋貴男*，今野　修，芳賀甚市，佐久間文隆

福島医学雑誌 57 ( 2 ) 123 - 130 2007

Carbohydrate status detecting by PNA is changeable through cancer prognosis from primary to metastatic nodal site: A possible prognostic factor in patient with node-positive lung adenocarcinoma.

SHIO,Yutaka*;SUZUKI,Hiroyuki*;KAWAGUCHI,T;OHSUGI,Jun*;HIGUCHI,Mitsunori*;FUJIU,K;KANNO,R;OHISHI,A;GOTOH,Mitsukazu*

Lung Cancer 57 ( 2 ) 187 - 92 2007

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Papers - SHIO Yutaka