Presentations -
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加齢黄斑変性の病態におけるレクチン経路の関与の可能性
第56回日本補体学会学術集会
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MASP-1 and MASP-3 play independent roles in activation of the lectin and alternative complement pathways
27th International Complement Workshop
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MRL/lprマウスのループス様糸球体腎炎におけるMASP-1/3の役割
第55回日本補体学会学術集会
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MASP-1、MASP-3はレクチン経路、第二経路の活性化に独立して寄与する
第55回日本補体学会学術集会
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SLEモデルMRL/lprマウスの抗dsDNA抗体産生における脾臓辺縁帯B細胞の役割
Rheumatology Conference 2018
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補体レクチン経路と第二経路を標的としたMAp44-fHの開発
研究連携セミナーポスター発表会2017
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Significant role for splenic marginal zone B cells in anti-dsDNA autoantibody production in lupus-prone mice with an MRL background
第46回日本免疫学会学術集会
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トワイライトセミナー:補体の基礎
第47回日本腎臟学会東部学術大会
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トワイライトセミナー:補体の基礎
第47回日本腎臟学会東部学術大会
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補体レクチン経路と第二経路を標的とする新規抗補体薬sMAP-fHの開発
第54回日本補体学会学術集会
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CRISPR/Cas9システムによるスプライシングバリアントの機能解析
研究連携セミナーポスター発表会2016
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Essential role of mannose-binding lectin-associated serine proteases-1/3 (MASP-1/3) in the development of lupus-like glomerulonephritis in MRL/lpr mice
XXVIth International Complement Workshop
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IFN-γ-receptor is required for intrafollicular localization of marginal zone B cells in the spleens of lupus-prone MRL+/+ mice
16th International Congress of Immunology
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補体制御因子sMAPとH因子を応用した新規抗補体薬の開発
平成28年サマーポスターセッション
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炎症性疾患に自然免疫はどう関与するのか〜補体の役割を中心に〜
第23回日本集中治療医学会東北地方会
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炎症性疾患に自然免疫はどう関与するのか〜補体の役割を中心に〜
第23回日本集中治療医学会東北地方会
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IFN-γ-receptor promotes intrafollicular localization of autoreactive marginal zone-B cells in the spleens of MRL+/+ mice
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Upregulation of C3 and alpha-2-Macroglobulin in cerebrospinal fluid of neuropsychiatric systemic lupus erythematosus
18th Annual Meeting of American College of Rheumatology
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Upregulation of C3 and alpha-2-Macroglobulin in cerebrospinal fluid of neuropsychiatric systemic lupus erythematosus
18th Annual Meeting of American College of Rheumatology
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Altered localization of CD19+ B cells in the splenic germinal centers of IFN-γ-receptor-1 deficient lupus-prone MRL+/+ mice
11th International Congress on Systemic Lupus Erythematosus
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Altered localization of CD19+ B cells in the splenic germinal centers of IFN-γ-receptor-1 deficient lupus-prone MRL+/+ mice
11th International Congress on Systemic Lupus Erythematosus
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マウス型リコンビナントタンパクrmMAp44-PA, rmMAp44-Igの作成と補体レクチン経路の阻害作用
第52回日本補体学会学術集会
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マウス型リコンビナントタンパクrmMAp44-PA, rmMAp44-Igの作成と補体レクチン経路の阻害作用
第52回日本補体学会学術集会
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マウス型リコンビナントタンパクrmMAp44-PA, rmMAp44-Igの作成と補体レクチン経路の阻害作用
第52回日本補体学会学術集会
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Altered localization of CD19+ B cells in the splenic germinal centers of IFN-γ-receptor-1 deficient lupus-prone MRL+/+ mice
11th International Congress on Systemic Lupus Erythematosus
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Altered localization of CD19+ B cells in the splenic germinal centers of IFN-γ-receptor-1 deficient lupus-prone MRL+/+ mice
11th International Congress on Systemic Lupus Erythematosus
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Altered localization of CD19+ B cells in the splenic germinal centers of IFN-γ-receptor-1 deficient lupus-prone MRL+/+ mice
11th International Congress on Systemic Lupus Erythematosus
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Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces
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A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice
2014-Annual Scientific Meeting of the American College of Rheumatology
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A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice
2014-Annual Scientific Meeting of the American College of Rheumatology
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腹膜炎ー敗血症モデルにおける補体因子MASP-1/3の役割
第51回補体シンポジウム
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腹膜炎ー敗血症モデルにおける補体因子MASP-1/3の役割
第51回補体シンポジウム
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Role of MASP-1/3 in activation of the alternative complement pathway and development of renal disease in a murine model of systemic lupus erythematosus
9th International Congress of Autoimmunity
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Role of MASP-1/3 in activation of the alternative complement pathway and development of renal disease in a murine model of systemic lupus erythematosus
9th International Congress of Autoimmunity
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腹膜炎ー敗血症モデルにおける補体因子MASP-1/3の役割
第51回補体シンポジウム
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Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces
Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces
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Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces
第43回日本免疫学会学術集会
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A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice
2014-Annual Scientific Meeting of the American College of Rheumatology
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A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice
2014-Annual Scientific Meeting of the American College of Rheumatology
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Role of MASP-1/3 in activation of the alternative complement pathway and development of renal disease in a murine model of systemic lupus erythematosus
9th International Congress of Autoimmunity
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Role of MASP-1/3 in activation of the alternative complement pathway and development of renal disease in a murine model of systemic lupus erythematosus
9th International Congress of Autoimmunity
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Role of MASP-1/3 in activation of the alternative complement pathway and development of renal disease in a murine model of systemic lupus erythematosus
9th International Congress of Autoimmunity
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Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces
Autoantibody-secreting marginal zone B cells develop significantly in lupus-prone MRL/lpr mice but not associated with expression of IFN-γ-receptor-1 on their surfaces
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A dual role for IFN-γ in development of peripheral B cells in lupus-prone MRL/lpr mice
2014-Annual Scientific Meeting of the American College of Rheumatology
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IFN-γ-receptor-1 is expressed abundantly on splenic B cells of MRL/lpr mice and is involved in peripheral B-cell survival/maintenance and autoantibody production
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Masp-1/3 deficient MRL/lpr mice lack the alternative complement pathway activation and are protected from development of lupus-like glomerulonephritis
The 77th Annual Meeting of the American College of Rheumatology
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Masp-1/3 deficient MRL/lpr mice lack the alternative complement pathway activation and are protected from development of lupus-like glomerulonephritis
The 77th Annual Meeting of the American College of Rheumatology
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Lack of IRF-1 accelerates development of tubulointerstitial nephritis and pulmonary granulomas with predominant Th2 polarity in lupus-prone MRL/lpr mice
15th International Congress of Immunology
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Aged IRF-4-deficient lupus-prone MRL/lpr mice show peripheral B-cell deficiency with elevated serum IFN-γ levels and increased expression of IFN-γ-receptor-1 on B cells
15th International Congress of Immunology
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Lupus-prone MRL/lpr mice express IFN-γ-receptor-1 abundantly on peripheral B cells that is responsible for peripheral B-cell survival/maintenance and autoantibody production
5th International Conference on “B cells and Autoimmunity"
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Lack of IRF-1 accelerates development of tubulointerstitial nephritis and pulmonary granulomas with predominant Th2 polarity in lupus-prone MRL/lpr mice
15th International Congress of Immunology
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Aged IRF-4-deficient lupus-prone MRL/lpr mice show peripheral B-cell deficiency with elevated serum IFN-γ levels and increased expression of IFN-γ-receptor-1 on B cells
15th International Congress of Immunology
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Aged IRF-4-deficient lupus-prone MRL/lpr mice show peripheral B-cell deficiency with elevated serum IFN-γ levels and increased expression of IFN-γ-receptor-1 on B cells
15th International Congress of Immunology
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Aged IRF-4-deficient lupus-prone MRL/lpr mice show peripheral B-cell deficiency with elevated serum IFN-γ levels and increased expression of IFN-γ-receptor-1 on B cells
15th International Congress of Immunology
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IFN-γ-receptor-1 is expressed abundantly on splenic B cells of MRL/lpr mice and is involved in peripheral B-cell survival/maintenance and autoantibody production
第42回日本免疫学会学術集会
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IFN-γ-receptor-1 is expressed abundantly on splenic B cells of MRL/lpr mice and is involved in peripheral B-cell survival/maintenance and autoantibody production
IFN-γ-receptor-1 is expressed abundantly on splenic B cells of MRL/lpr mice and is involved in peripheral B-cell survival/maintenance and autoantibody production
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Lack of IRF-1 accelerates development of tubulointerstitial nephritis and pulmonary granulomas with predominant Th2 polarity in lupus-prone MRL/lpr mice
15th International Congress of Immunology
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Lack of IRF-1 accelerates development of tubulointerstitial nephritis and pulmonary granulomas with predominant Th2 polarity in lupus-prone MRL/lpr mice
15th International Congress of Immunology
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Lupus-prone MRL/lpr mice express IFN-γ-receptor-1 abundantly on peripheral B cells that is responsible for peripheral B-cell survival/maintenance and autoantibody production
5th International Conference on “B cells and Autoimmunity”
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Lupus-prone MRL/lpr mice express IFN-γ-receptor-1 abundantly on peripheral B cells that is responsible for peripheral B-cell survival/maintenance and autoantibody production
5th International Conference on “B cells and Autoimmunity”
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Masp-1/3 deficient MRL/lpr mice lack the alternative complement pathway activation and are protected from development of lupus-like glomerulonephritis
The 77th Annual Meeting of the American College of Rheumatology
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Masp-1/3 deficient MRL/lpr mice lack the alternative complement pathway activation and are protected from development of lupus-like glomerulonephritis
The 77th Annual Meeting of the American College of Rheumatology
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Aged IRF-4-deficient lupus-prone MRL/lpr mice show peripheral B-cell deficiency with elevated serum IFN-γ levels and increased expression of IFN-γ-receptor-1 on B cells
15th International Congress of Immunology
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Masp-1/3 deficient MRL/lpr mice lack the alternative complement pathway activation and are protected from development of lupus-like glomerulonephritis
The 77th Annual Meeting of the American College of Rheumatology
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Lack of IRF-1 accelerates development of tubulointerstitial nephritis and pulmonary granulomas with predominant Th2 polarity in lupus-prone MRL/lpr mice
15th International Congress of Immunology
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IFN-γ-receptor-1 is expressed abundantly on splenic B cells of MRL/lpr mice and is involved in peripheral B-cell survival/maintenance and autoantibody production
IFN-γ-receptor-1 is expressed abundantly on splenic B cells of MRL/lpr mice and is involved in peripheral B-cell survival/maintenance and autoantibody production
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Lack of interferon regulatory factor-1 accelerates development of interstitial nephritis, renal vasculitis, and pulmonary granulomas with predominant Th2 polarity in lupus-prone MRL/lpr mice
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IRF-1 deficient lupus-prone MRL/lpr mice show reduced glomerulonephritis but develop severe interstitial nephritis, renal vasculitis and pulmonary granulomas with propensity for Th2 polarity
The 76th Annual Meeting of the American College of Rheumatology
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MBL-associated serine protease (MASP)-1/3 promotes the inhibition of the alternative pathway activation
XXIV International Complement Workshop
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Role of complement in a murine model of peanut-induced anaphylaxis
XXIV International Complement Workshop
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IRF-4欠損MRL/lprマウスはTh1過剰応答を起こし複数の組織に肉芽腫生病変を発症する
第40回日本免疫学会総会・学術集会
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Interferon regulatory factor-4 deficient lupus-prone MRL/lpr mice show strong propensity for Th1 polarity and develop granulomatous lesions in multiple organs
The 75th Annual Meeting of the American College of Rheumatology
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The benefit of targeted and selective inhibition of the alternative complement pathway for modulating autoimmunity and renal disease in murine models of systemic lupus erythematosus
The 5th Complement Workshop
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IRF4-deficient lupus-prone MRL/lpr mice lack serum Ig/auto-Abs and Th17 cells but develop non-immune complex-mediated diffuse proliferative glomerulonephritis and dermatitis/ear necrosis
The 74th Annual Meeting of the American College of Rheumatology
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ループス腎炎と補体・補体第2経路を特異的に標的とする治療戦略
第47回補体シンポジウム
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IRF4-deficient lupus-prone MRL/lpr mice lack serum immunoglobulin and glomerular immune complex/C3 deposits but develop proliferative glomerulonephritis and dermatitis/ear necrosis
14th International Congress of Immunology
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転写因子IRF4欠損SLEモデルマウスが示唆するループス腎炎の新たなメカニズム
Rheumatology Conference 2010
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Targeted Inhibition of the Alternative Pathway Ameliorates Progression of Renal Disease in Lupus-prone MRL/lpr Mice
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IRF4-deficient lupus-prone MRL/lpr mice lack serum immunoglobulin and glomerular immune complex/C3 deposits but develop diffuse proliferative glomerulonephritis and dermatitis/ear necrosis
Immunodeficiencies and Autoimmune Diseases Scientific Colloquium
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Targeted Inhibition of the Alternative Pathway Ameliorates Progression of Renal Disease in Murine Models of Systemic Lupus Erythematosus
The 73nd Annual Meeting of the American College of Rheumatology
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補体第2経路特異的阻害剤CR2-fH融合蛋白を用いたループス様腎炎の抑制効果
第18回 日本リウマチ学会 北海道・東北支部学術集会
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インターフェロン調節因子-4(IRF4)遺伝子欠損 MRL/lpr マウスを用いたループス様腎炎の検討
第18回 日本リウマチ学会 北海道・東北支部学術集会
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Targeted Inhibition of the Alternative Pathway by CR2-fH Fusion Protein Ameliorates Progression of Renal Disease in MRL/lpr Mice
The 72nd Annual Meeting of the American College of Rheumatology
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Interferon-Regulatory Factor 4 Is Required for Full Expression of Lupus Nephritis in MRL/lpr Mice
The 72nd annual meeting of the American College of Rheumatology