研究者詳細 - 大河原　浩

論文 - 大河原　浩

分割表示 >> ／全件表示78 件中 1 - 78 件目

Dasatinib induces endothelial-to-mesenchymal transition in human vascular-endothelial cells: counteracted by cotreatment with bosutinib.

Alkebsi L, Wang X, Ohkawara H, Fukatsu M, Mori H, Ikezoe T

International journal of hematology 113 ( 3 ) 441 - 455 2021年3月（ ISSN:0925-5710 ）

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia.

Harada-Shirado K, Wang X, Mori H, Fukatsu M, Takahashi H, Shichishima-Nakamura A, Kimura S, Ohkawara H, Yamada S, Ito T, Ikezoe T

International journal of hematology 111 ( 3 ) 378 - 387 2020年3月（ ISSN:0925-5710 ）

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia(和訳中)

Harada-Shirado Kayo, Wang Xintao, Mori Hirotaka, Fukatsu Masahiko, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Kimura Satoshi, Ohkawara Hiroshi, Yamada Shingo, Ito Takashi, Ikezoe Takayuki

International Journal of Hematology 111 ( 3 ) 378 - 387 2020年3月（ ISSN:0925-5710 ）

Circulating intranuclear proteins may play a role in development of disseminated intravascular coagulation in individuals with acute leukemia.

Harada-Shirado Kayo, Wang Xintao, Mori Hirotaka, Fukatsu Masahiko, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Kimura Satoshi, Ohkawara Hiroshi, Yamada Shingo, Ito Takashi, Ikezoe Takayuki

International journal of hematology 111 ( 3 ) 378 - 387 2020年3月（ ISSN:0925-5710 ）

Optimal timing of apheresis for the efficient mobilization of peripheral blood progenitor cells recruited by high-dose granulocyte colony-stimulating factor in healthy donors.

Kimura S, Ohkawara H, Minakawa K, Fukatsu M, Mori H, Takahashi H, Harada-Shirado K, Ohara Y, Takahashi N, Mochizuki K, Sano H, Nollet KE, Ogawa K, Ohto H, Kikuta A, Ikeda K, Ikezoe T

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 102737 2020年2月（ ISSN:1473-0502 ）

The link between interleukin-1β and acute myocardial infarction in chronic myeloid leukemia patients treated with nilotinib: cross-sectional study.

Mori H, Sukegawa M, Fukatsu M, Sano T, Takahashi H, Harada K, Kimura S, Ohkawara H, Nakamura K, Mita M, Saito T, Hamazaki Y, Ohta M, Ikezoe T

Annals of hematology 99 ( 2 ) 359 - 361 2020年2月（ ISSN:0939-5555 ）

The link between interleukin-1β and acute myocardial infarction in chronic myeloid leukemia patients treated with nilotinib: cross-sectional study.

Hirotaka Mori, Masumi Sukegawa, Masahiko Fukatsu, Takahiro Sano, Hiroshi Takahashi, Kayo Harada, Satoshi Kimura, Hiroshi Ohkawara, Kenichi Nakamura, Masayuki Mita, Tomiyoshi Saito, Yoichi Hamazaki, Masatsugu Ohta, Takayuki Ikezoe

Annals of hematology 99 ( 2 ) 359 - 361 2020年2月（ ISSN:0939-5555 ）

Integral role of receptor for advanced glycation end products(RAGE) in nondiabetic atherosclerosis(和訳中)

Uekita Hironori, Ishibashi Toshiyuki, Shiomi Masashi, Koyama Hidenori, Ohtsuka Shukuko, Yamamoto Hiroshi, Yamagishi Shoichi, Inoue Hiroyoshi, Itabe Hiroyuki, Sugimoto Koichi, Kamioka Masashi, Ohkawara Hiroshi, Wada Ikuo, Takeishi Yasuchika

Fukushima Journal of Medical Science 65 ( 3 ) 109 - 121 2020年1月（ ISSN:0016-2590 ）

Integral role of receptor for advanced glycation end products (RAGE) in nondiabetic atherosclerosis

Hironori Uekita, Toshiyuki Ishibashi, Masashi Shiomi , Hidenori Koyama, Shukuko Ohtsuka, Hiroshi Yamamoto, Shoichi Yamagishi, Hiroyoshi Inoue, Hiroyuki Itabe, Koichi Sugimoto, Masashi Kamioka, Hiroshi Ohkawara, Ikuo Wada, Takeishi Yasuchika.

Fukushima Journal of Medical Science 65 ( 3 ) 109 - 121 2019年12月

Intestinal Behçet disease associated with myelodysplastic syndrome accompanying trisomy 8 successfully treated with abdominal surgery followed by hematopoietic stem cell transplantation: A case report.

Asano T, Sato S, Furuya MY, Takahashi H, Shichishima-Nakamura A, Ohkawara H, Fujiwara T, Gunji N, Hashimoto C, Momma T, Saito M, Nakano H, Watanabe G, Temmoku J, Fujita Y, Matsuoka N, Kobayashi H, Watanabe H, Mouri M, Mashiyama F, Sakuma H, Ohira H, Mori M, Ikezoe T, Migita K

Medicine 98 ( 46 ) e17979 2019年11月（ ISSN:0025-7974 ）

A critical role of the Gas6-Mer axis in endothelial dysfunction contributing to TA-TMA associated with GVHD.

Furukawa M, Wang X, Ohkawara H, Fukatsu M, Alkebsi L, Takahashi H, Harada-Shirado K, Shichishima-Nakamura A, Kimura S, Ogawa K, Ikezoe T

Blood advances 3 ( 14 ) 2128 - 2143 2019年7月（ ISSN:2473-9529 ）

造血器腫瘍と免疫・凝固系　第4回　造血幹細胞移植後の免疫凝固異常

大河原浩, 池添隆之

Thrombosis Medicine 9 ( 1 ) 60 - 66 2019年3月（ ISSN:2186-0327 ）

Predicting factors of transmural thermal injury after cryoballoon pulmonary vein isolation.

Matsumoto Y, Kaneshiro T, Hijioka N, Nodera M, Yamada S, Kamioka M, Yoshihisa A, Ohkawara H, Hikichi T, Suzuki H, Takeishi Y

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 54 ( 2 ) 101 - 108 2019年3月（ ISSN:1383-875X ）

Lenalidomide as a Beneficial Treatment Option for Renal Impairment Caused by Light Chain Deposition Disease

Kimura Satoshi, Ohkawara Hiroshi, Ogawa Kazuei, Tanaka Mizuko, Sano Takahiro, Harada-Shirado Kayo, Takahashi Hiroshi, Ueda Koki, Shichishima-Nakamura Akiko, Matsumoto Hayato, Ikeda Kazuhiko, Kazama Junichiro James, Hashimoto Yuko, Ikezoe Takayuki

Internal Medicine 57 ( 24 ) 3651 - 3657 2018年12月（ ISSN:0918-2918 ）

Distinct Forms of Esophageal Lesions After Radiofrequency and Cryoballoon Pulmonary Vein Isolation.

Kaneshiro T, Matsumoto Y, Hijioka N, Nodera M, Yamada S, Kamioka M, Yoshihisa A, Ohkawara H, Suzuki H, Takeishi Y

JACC. Clinical electrophysiology 4 ( 12 ) 1642 - 1643 2018年12月（ ISSN:2405-500X ）

Lenalidomide as a Beneficial Treatment Option for Renal Impairment Caused by Light Chain Deposition Disease: A Case Series

Kimura Satoshi, Matsumoto Hayato, Ikeda Kazuhiko, Kazama Junichiro James, Hashimoto Yuko, Ikezoe Takayuki, Ohkawara Hiroshi, Ogawa Kazuei, Tanaka Mizuko, Sano Takahiro, Harada-Shirado Kayo, Takahashi Hiroshi, Ueda Koki, Shichishima-Nakamura Akiko

Internal medicine (Tokyo, Japan) 2018年8月（ ISSN:0918-2918 ）

気管に限局して発症し気管閉塞を来たした節外性NK/T細胞リンパ腫、鼻型

高橋裕志, 大河原浩, 七島晶子, 深津真彦, 佐野隆浩, 原田佳代, 木村哲, 東川隆一, 田崎和洋, 橋本優子, 小川一英, 池添隆之

臨床血液 59 ( 8 ) 1012 - 1015 2018年8月（ ISSN:0485-1439 ）

気管に限局して発症し気管閉塞を来たした節外性NK/T細胞リンパ腫、鼻型

高橋裕志, 大河原浩, 七島晶子, 深津真彦, 佐野隆浩, 原田佳代, 木村哲, 東川隆一, 田崎和洋, 橋本優子, 小川一英, 池添隆之

臨床血液 59 ( 8 ) 1012 - 1015 2018年8月（ ISSN:0485-1439 ）

A case of TAFRO syndrome successfully treated with cyclosporin A and tocilizumab

Asano Tomoyuki, Yashiro Makiko, Watanabe Aya, Sato Shuzo, Kobayashi Hiroko, Watanabe Hiroshi, Ohkawara Hiroshi, Murakami Fumi, Hashimoto Yuko, Koga Tomohiro, Kawakami Atsushi, Migita Kiyoshi

Modern Rheumatology Case Reports 2 ( 2 ) 209 - 213 2018年7月

Cytoprotective and pro-angiogenic functions of thrombomodulin are preserved in the C loop of the fifth epidermal growth factor-like domain.

Wang X, Pan B, Honda G, Wang X, Hashimoto Y, Ohkawara H, Xu K, Zeng L, Ikezoe T

Haematologica 2018年6月（ ISSN:0390-6078 ）

Defibrotide Stimulates Angiogenesis and Protects Endothelial Cells from Calcineurin Inhibitor-Induced Apoptosis via Upregulation of AKT/Bcl-xL.

Wang X, Pan B, Hashimoto Y, Ohkawara H, Xu K, Zeng L, Ikezoe T

Thrombosis and haemostasis 118 ( 1 ) 161 - 173 2018年1月（ ISSN:0340-6245 ）

Distinct forms of esophageal lesions after radiofrequency and cryoballoon pulmonary vein isolation

Takashi Kaneshiro, Yoshiyuki Matsumoto, Naoko Hijioka, Minoru Nodera, Shinya Yamada, Masashi Kamioka, Akiomi Yoshihisa, Hiroshi Ohkawara, Hitoshi Suzuki, Yasuchika Takeishi

JACC: Clinical Electrophysiology 4 ( (12) ) 1642 - 1643 2018年

Anatomical predisposing factors of transmural thermal injury after pulmonary vein isolation

Takashi Kaneshiro, Yoshiyuki Matsumoto, Minoru Nodera, Masashi Kamioka, Yoshiyuki Kamiyama, Akiomi Yoshihisa, Hiroshi Ohkawara, Hitoshi Suzuki, Yasuchika Takeishi

Europace 20 ( (7) ) 1122 - 1128 2018年

Airway obstruction due to localized tracheal lesion of extranodal NK/T-cell lymphoma, nasal type

TAKAHASHI Hiroshi, HASHIMOTO Yuko, OGAWA Kazuei, IKEZOE Takayuki, OHKAWARA Hiroshi, SHICHISHIMA-NAKAMURA Akiko, FUKATSU Masahiko, SANO Takahiro, HARADA-SHIRADO Kayo, KIMURA Satoshi, TOGAWA Ryuichi, TASAKI Kazuhiro

Rinsho Ketsueki 59 ( 8 ) 1012 - 1015 2018年（ ISSN:0485-1439 ）

Steroid-resistant autoimmune myelofibrosis in a patient with autoimmune hepatitis and Evans syndrome complicated with increased expression of TGF-β in the bone marrow: a case report.

Ohkawara H, Furukawa M, Ikeda K, Shichishima-Nakamura A, Fukatsu M, Sano T, Ueda K, Kimura S, Kanai R, Oka Y, Murakami F, Suzuki O, Hashimoto Y, Ogawa K, Ikezoe T

International journal of hematology 106 ( 5 ) 718 - 724 2017年11月（ ISSN:0925-5710 ）

Steroid-resistant autoimmune myelofibrosis in a patient with autoimmune hepatitis and Evans syndrome complicated with increased expression of TGF-β in the bone marrow: a case report(和訳中)

Ohkawara Hiroshi, Furukawa Miki, Ikeda Kazuhiko, Shichishima-Nakamura Akiko, Fukatsu Masahiko, Sano Takahiro, Ueda Koki, Kimura Satoshi, Kanai Risa, Oka Yuka, Murakami Fumi, Suzuki Osamu, Hashimoto Yuko, Ogawa Kazuei, Ikezoe Takayuki

International Journal of Hematology 106 ( 5 ) 718 - 724 2017年11月（ ISSN:0925-5710 ）

The BCR/ABL tyrosine kinase inhibitor, nilotinib, stimulates expression of IL-1β in vascular endothelium in association with downregulation of miR-3p.

Sukegawa M, Wang X, Nishioka C, Pan B, Xu K, Ohkawara H, Hamasaki Y, Mita M, Nakamura K, Okamoto M, Shimura H, Ohta M, Ikezoe T

Leukemia research 58 83 - 90 2017年7月（ ISSN:0145-2126 ）

Hmga2 collaborates with <i>JAK2</i>V617F in the development of myeloproliferative neoplasms.

Ueda K, Ikeda K, Ikezoe T, Harada-Shirado K, Ogawa K, Hashimoto Y, Sano T, Ohkawara H, Kimura S, Shichishima-Nakamura A, Nakamura Y, Shikama Y, Mori T, Mason PJ, Bessler M, Morishita S, Komatsu N, Shide K, Shimoda K, Koide S, Aoyama K, Oshima M, Iwama A, Takeishi Y

Blood advances 1 ( 15 ) 1001 - 1015 2017年6月（ ISSN:2473-9529 ）

Anatomical predisposing factors of transmural thermal injury after pulmonary vein isolation.

Kaneshiro T, Matsumoto Y, Nodera M, Kamioka M, Kamiyama Y, Yoshihisa A, Ohkawara H, Suzuki H, Takeishi Y

Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 2017年6月（ ISSN:1099-5129 ）

Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms

Koki Ueda, Kazuhiko Ikeda, Takayuki Ikezoe, Kayo Harada-Shirado, Kazuei Ogawa, Yuko Hashimoto, Takahiro Sano, Hiroshi Ohkawara, Satoshi Kimura, Akiko Shichishima-Nakamura, Yuichi Nakamura, Yayoi Shikama, Tsutomu Mori, Philip J. Mason, Monica Bessler, Soji Morishita, Norio Komatsu, Kotaro Shide, Kazuya Shimoda, Shuhei Koide, Kazumasa Aoyama, Motohiko Oshima, Atsushi Iwama, Yasuchika Takeishi

blood advances 1 ( 15 ) 1001 - 1015 2017年6月

A possible role of low regulatory T cells in anti-acetylcholine receptor antibody positive myasthenia gravis after bone marrow transplantation.

Fukatsu M, Murakami T, Ohkawara H, Saito S, Ikeda K, Kadowaki S, Sasaki I, Segawa M, Soeda T, Hoshi A, Takahashi H, Shichishima-Nakamura A, Ogawa K, Sugiura Y, Ohto H, Takeishi Y, Ikezoe T, Ugawa Y

BMC neurology 17 ( 1 ) 93 2017年5月

Autocrine and Paracrine Interactions between Multiple Myeloma Cells and Bone Marrow Stromal Cells by Growth Arrest-specific Gene 6 Cross-talk with Interleukin-6.

Furukawa M, Ohkawara H, Ogawa K, Ikeda K, Ueda K, Shichishima-Nakamura A, Ito E, Imai JI, Yanagisawa Y, Honma R, Watanabe S, Waguri S, Ikezoe T, Takeishi Y

The Journal of biological chemistry 292 ( 10 ) 4280 - 4292 2017年3月（ ISSN:0021-9258 ）

A possible role of low regulatory T cells in anti-acetylcholine receptor antibody positive myasthenia gravis after bone marrow transplantation

Masahiko Fukatsu, Takenobu Murakami, Hiroshi Ohkawara, Shunichi Saito, Kazuhiko Ikeda, Suguru Kadowaki, Itaru Sasaki, Mari Segawa, Tomoko Soeda, Akihiko Hoshi, Hiroshi Takahashi, Akihiko Shichishima-Nakamura, Kazuei Ogawa, Yoshihiro Sugita, Hitoshi Ohto, Yasuchika Takeishi, Takayuki Ikezoe, Yoshikazu Ugawa

BMC Neurology 17 ( 1 ) 93 2017年

Infected pancreatic pseudocyst ruptured into stomach and colon associated with splenic artery pseudoaneurysm

OHKAWARA, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; IKEDA, Kazuhiko*; SUKEGAWA, Masumi*; FURUKAWA, Miki*; SANO, Takahiro*; UEDA, Koki*; KIMURA, Satoshi*; YOSHIHISA, Akiomi*; NOJI, Hideyoshi*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

Journal of the Pancreas 17 ( 3 ) 324 - 327 2016年

MT1-MMP)(MEMBRANE TYPE 1-MATRIX METALLOPROTEINASE(MT1-MMP) IDENTIFIED AS A MULTIFUNCTIONAL REGULATOR OF VASCULAR RESPONSES

Ohkawara Hiroshi, Ikeda Kazuhiko, Ogawa Kazuei, Takeishi Yasuchika

Fukushima Journal of Medical Science 61 ( 2 ) 91 - 100 2015年12月（ ISSN:0016-2590 ）

Persistent complete remission of acute leukemic-phase CCR4-positive gamma-delta peripheral T-cell lymphoma by autologous stem cell transplantation with mogamulizumab

Furukawa Miki, Ikeda Kazuhiko, Ohkawara Hiroshi, Saito Shunichi, Takahashi Hiroshi, Udea Koki, Matsumoto Hayato, Hashimoto Yuko, Ohto Hitoshi, Ogawa Kazuei, Takeishi Yasuchika

International Journal of Hematology 102 ( 4 ) 498 - 505 2015年10月（ ISSN:0925-5710 ）

Membrane type 1-matrix metalloproteinase (MT1-MMP) identified as a multifunctional regulator of vascular responses

OHKAWARA, Hiroshi*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

Fukushima Journal of Medical Science 61 ( 2 ) 91 - 100 2015年9月

Erratum to: Persistent complete remission of acute leukemic-phase CCR4-positive gamma-delta peripheral T-cell lymphoma by autologous stem cell transplantation with mogamulizumab.

Furukawa M, Ikeda K, Ohkawara H, Saito S, Takahashi H, Ueda K, Matsumoto H, Hashimoto Y, Ohto H, Ogawa K, Takeishi Y

International journal of hematology 102 ( 1 ) 147 2015年7月（ ISSN:0925-5710 ）

Persistent complete remission of acute leukemic-phase CCR4-positive gamma-delta peripheral T-cell lymphoma by autologous stem cell transplantation with mogamulizumab

FURUKAWA, Miki*; IKEDA, Kazuhiko*; OHKAWARA, Hiroshi*; SAITO, Shunichi*; TAKAHASHI, Hiroshi*; UEDA, Koki*; MATSUMOTO, Hayato*; HASHIMOTO, Yuko*; OHTO, Hitoshi*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

International Journal of Hematology 102 ( 4 ) 498 - 505 2015年6月

Dysregulation of the MIRLET7/HMGA2 axis with methylation of the CDKN2A promoter in myeloproliferative neoplasms

HARADA-SHIRADO, Kayo*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; OHKAWARA, Hiroshi*; KIMURA, Hideo; KAI, Tatsuyuki; NOJI, Hideyoshi*; MORISHITA, Soji; KOMATSU, Norio; TAKEISHI, Yasuchika*

British Journal of Haematology 168 ( 3 ) 338 - 349 2015年

CD4+ T cells in aged or thymectomized recipients of allogenic stem cell transplantations

TAKAHASHI, Hiroshi*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; SAITO, Syunnichi*; NGOMA, Alain*; MASHIMO, Yumiko*; UEDA, Koki*; FURUKAWA, Miki*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; NOLLET, Kenneth*; OHTO, Hitoshi*; TAKEISHI, Yasuchika*

Biological Research 48 41 2015年

Post-engraftment blood transfusion and outcomes of bone marrow transplantation

MASHIMO, Yumiko*; IKEDA, Kazuhiko*; OHKAWARA, Hiroshi*; TAKAHASHI, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; FURUKAWA, Miki*; KIMURA, Satoshi*; UEDA, Koki*; NOJI, Hideyoshi*; OGAWA, Kazuei*; NOLLET, Kenneth*; OHTO, Hitoshi*; TAKEISHI, Yasuchika*

ISBT Science Series 10 ( 2 ) 93 - 99 2015年

Severe Immune Thrombocytopenia Possibly Elicited by the Anti-influenza Viral Agent Peramivir

Harada-Shirado Kayo, Ikeda Kazuhiko, Furukawa Miki, Sukegawa Masumi, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Ohkawara Hiroshi, Noji Hideyoshi, Kawabata Kinuyo, Saito Shun-ichi, Ohto Hitoshi, Ogawa Kazuei, Takeishi Yasuchika

Internal Medicine 53 ( 20 ) 2369 - 2371 2014年10月（ ISSN:0918-2918 ）

Pleural Solitary Fibrous Tumor Complicated with Autoimmune Hemolytic Anemia

Takahashi Hiroaki, Ohkawara Hiroshi, Ikeda Kazuhiko, Harada-Shirado Kayo, Furukawa Miki, Sukegawa Masumi, Shichishima-Nakamura Akiko, Noji Hideyoshi, Wakamatsu Saho, Tasaki Kazuhiro, Suzuki Hiroyuki, Ogawa Kazuei, Takeishi Yasuchika

Internal Medicine 53 ( 14 ) 1549 - 1552 2014年7月（ ISSN:0918-2918 ）

当院における遺伝子組換えトロンボモジュリン製剤の使用経験

松本勇人, 古川未希, 原田佳代, 高橋裕志, 七島晶子, 大河原浩, 池田和彦, 野地秀義, 小川一英, 竹石恭知

東北止血・血栓研究会会誌 XXVI ( 1 ) 4 - 5 2014年5月（ ISSN:0914-6598 ）

Somatic 15q break after long-term stable disease in acute myeloid leukemia

HARADA-SHIRADO, Kayo*; IKEDA, Kazuhiko*; MATSUMOTO, Hayato*; SHIGA, Yutaka; FURUKAWA, Miki*; TAKAHASHI, Hiroshi*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; HASHIMOTO, Yuko*; WAGURI, Satoshi*; WATANABE, Shinya*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

Clinical Lymphoma, Myeloma & Leukemia 14 ( 2 ) e69-e72 2014年

Pleural solitary fibrous tumor complicated with autoimmune hemolytic anemia

TAKAHASHI, Hiroshi*; OHKAWARA, Hiroshi*; IKEDA, Kazuhiko*; HARADA-SHIRADO, Kayo*; FURUKAWA, Miki*; SUKEGAWA, Masumi*; SHICHISHIMA-NAKAMURA, Akiko*; NOJI, Hideyoshi*; WAKAMATSU, Saho; TASAKI*, Kazuhiro; SUZUKI*, Hiroyuki; OGAWA*, Kazuei*; TAKEISHI, Yasuchika*

Internal Medicine 53 ( 14 ) 1549 - 1552 2014年

Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-α-induced procoagulant activity and apoptosis in endothelial cells

OHKAWARA, Hiroshi*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; IKEDA, Kazuhiko*; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

PLoS One 9 ( 8 ) e105697 2014年

Severe immune thrombocytopenia possibly elicited by the anti-influenza viral agent peramivir

HARADA-SHIRADO, Kayo*; IKEDA, Kazuhiko*; FURUKAWA, Miki*; SUKEGAWA, Masumi*; TAKAHASHI, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; KAWABATA, Kinuyo; SAITO, Shun-ichi; OHTO, Hitoshi; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

Internal Medicine 53 ( 10 ) 2369 - 2371 2014年

Receptor for advanced glycation end products - membrane type1 matrix metalloproteinase axis regulates tissue factor expression via RhoA and Rac1 activation in high-mobility group box-1 stimulated endothelial cells

SUGIMOTO, Koichi*; OHKAWARA, Hiroshi*; NAKAMURA, Yuichi*; TAKUWA, Yoh; ISHIBASHI, Toshiyuki*; TAKEISHI, Yasuchika*

PLoS One 9 ( 12 ) e114429 2014年

Severe immune thrombocytopenia possibly elicited by the anti-influenza viral agent peramivir.

Harada-Shirado K, Ikeda K, Furukawa M, Sukegawa M, Takahashi H, Shichishima-Nakamura A, Ohkawara H, Noji H, Kawabata K, Saito S, Ohto H, Ogawa K, Takeishi Y

Internal medicine (Tokyo, Japan) 53 ( 20 ) 2369 - 71 2014年（ ISSN:0918-2918 ）

Pleural solitary fibrous tumor complicated with autoimmune hemolytic anemia.

Takahashi H, Ohkawara H, Ikeda K, Harada-Shirado K, Furukawa M, Sukegawa M, Shichishima-Nakamura A, Noji H, Wakamatsu S, Tasaki K, Suzuki H, Ogawa K, Takeishi Y

Internal medicine (Tokyo, Japan) 53 ( 14 ) 1549 - 52 2014年（ ISSN:0918-2918 ）

Pulmonary Hypertension and Refractory Heart Failure in a Patient with Crow-Fukase (POEMS) Syndrome

Yokokawa Tetsuro, Nakazato Kazuhiko, Kanno Yuki, Mizukami Hiroyuki, Kobayashi Atsushi, Yoshihisa Akiomi, Takahashi Hiroshi, Shichishima-Nakamura Akiko, Ohkawara Hiroshi, Noji Hideyoshi, Suzuki Hitoshi, Saitoh Shu-ichi, Ogawa Kazuei, Hisa Shinichi, Takeishi Yasuchika

Internal Medicine 52 ( 10 ) 1061 - 1065 2013年5月（ ISSN:0918-2918 ）

Pulmonary hypertension and refractory heart failure in a patient with Crow-Fukase (POEMS) syndrome

YOKOKAWA, Tetsuro*; NAKAZATO, Kazuhiko*; KANNO, Yuki*; MIZUKAMI, Hiroyuki*; KOBAYASHI, Atsushi*; YOSHIHISA, Akiomi*; TAKAHASHI, Hiroshi*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; SUZUKI, Hitoshi*; SAITOH, Shu-ichi*; OGAWA, Kazuei*; HISA, Shinichi; TAKEISHI, Yasuchika*

Internal Medicine 52 ( 10 ) 1061 - 1065 2013年

Pulmonary hypertension and refractory heart failure in a patient with Crow-Fukase (POEMS) syndrome.

Yokokawa T, Nakazato K, Kanno Y, Mizukami H, Kobayashi A, Yoshihisa A, Takahashi H, Shichishima-Nakamura A, Ohkawara H, Noji H, Suzuki H, Saitoh S, Ogawa K, Hisa S, Takeishi Y

Internal medicine (Tokyo, Japan) 52 ( 10 ) 1061 - 5 2013年（ ISSN:0918-2918 ）

A Japanese case of chronic lymphocytic leukemia with t(1;6)

HARADA, Kayo*; IKEDA, Kazuhiko*; MATSUMOTO, Hayato*; FURUKAWA, Miki*; TAKAHASHI, Hiroshi*; OHKAWARA, Hiroshi*; NOJI, Hideyoshi*; TASAKI, Kazuhiro; ABE, Masafumi; OGAWA, Kazuei*; TAKEISHI, Yasuchika*

Experimental Hematology & Oncology 1 ( 1 ) 28 2012年

特集　動脈硬化研究の最新知見　動脈硬化の発症・進展における酸化ストレスの役割

大河原浩*, 竹石恭知*

2 ( 4 ) 252 - 257 2011年

Involvement of membrane type 1-matrix metalloproteinase (MT1-MMP) in RAGE activation signaling pathways

KAMIOKA, Masashi*; ISHIBASHI, Toshiyuki*; OHKAWARA, Hiroshi*; NAGAI, Ryoji; SUGIMOTO, Koichi*; UEKITA, Hironori*; MATSUI, Takanori; YAMAGISHI, Sho-ichi; ANDO, Katsuya*; SAKAMOTO, Takayuki*; TAKUWA, Yoh; WADA, Ikuo; SHIOMI, Masashi; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

Journal of Cellular Physiology 226 ( 6 ) 1554 - 1563 2011年

Crucial role of membrane type 1 matrix metalloproteinase (MT1-MMP) in RhoA/Rac1-dependent signaling pathways in thrombin-stimulated endothelial cells

ANDO, Katuya*; ISHIBASHI, Toshiyuki*; OHKAWARA, Hiroshi*; INOUE, Nobutaka; SUGIMOTO, Koichi*; UEKITA, Hironori*; HU, Chengjun; OKAMOTO, Yasuo; TAKUWA, Yoh; TAKEISHI, Yasuchika*

Journal of Atherosclerosis and Thrombosis 18 ( 9 ) 762 - 773 2011年

Preventive effect of chronic endothelin type A receptor antagonist on coronary microvascular spasm induced by repeated epicardial coronary artery endothelial denudation in pigs

OSUGI, Taku*; SAITOH, Shu-ichi*; MATSUMOTO, Ken*; MUTO, Mitsuru*; AIKAWA, Kazuhiko*; OHKAWARA, Hiroshi*; SUGIMOTO, Koichi*; KAMIOKA, Masashi*; ISHIBASHI, Toshiyuki*; MARUYAMA, Yukio*

Journal of Atherosclerosis and Thrombosis 17 ( 1 ) 54 - 63 2010年

Blockade of renin-angiotensin system attenuates advanced glycation end products-mediated signaling pathways

KAMIOKA, Masashi*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; UEKITA, Hironori*; NAGAI, Ryoji; SAKAMOTO, Nobuo*; ANDO, Katsuya*; OHKAWARA, Hiroshi*; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

Journal of Atherosclerosis and Thrombosis 17 ( 6 ) 590 - 600 2010年

Preventive effects of pravastatin on thrombin-triggered vascular responses via Akt/eNOS and RhoA/Rac1 pathways in vivo

OHKAWARA, Hiroshi*; ISHIBASHI, Toshiyuki*; SAITOH, Shu-ichi*; INOUE, Nobutaka; SUGIMOTO, Koichi*; KAMIOKA, Masashi*; UEKITA, Hironori*; KANESHIRO, Takashi*; ANDO, Katsuya*; TAKUWA, Yoh; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

Cardiovascular Research 88 ( 3 ) 492 - 501 2010年

Hematopoietic stem cell transplantation in the Department of Hematology, Fukushima Medical University

OGAWA, Kazuei*; NOJI, Hideyoshi*; FURUKAWA, Miki*; HARADA-SHIRADO, Kayo*; MASHIMO, Yumiko*; TAKAHASHI, Hiroshi*; MATSUMOTO, Hayato*; KIMURA, Satoshi*; SHICHISHIMA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; IKEDA, Kazuhiko*; OHTO, Hitoshi; TAKEISHI, Yasuchika*

Fukushima Journal of Medical Science 56 ( 2 ) 107 - 114 2010年

A long-term remission of renal amyloidosis with nephrotic syndrome after autologous peripheral blood stem-cell transplantation

OGAWA, Kazuei*; IKEDA, Kazuhiko*; FURUKAWA, Miki*; HARADA-SHIRADO, Kayo*; MASHIMO, Yumiko*; TAKAHASHI, Hiroshi*; MATSUMOTO, Hayato*; KIMURA, Satoshi*; SHICHISHINA-NAKAMURA, Akiko*; OHKAWARA, Hiroshi*; HASHIMOTO, Yuko; ASAHI, Koichi; NOJI, Hideyoshi*; OHTO, Hitoshi; TAKEISHI, Yasuchika*

Fukushima Journal of Medical Science 56 ( 2 ) 151 - 156 2010年

Bone marrow-derived progenitor cells prevent thrombin-induced increase in lung vascular permeability

ZHAO, Yidan; OHKAWARA, Hiroshi*; VOGEL, Stephen; MALIK, Asrar; ZHAO, You-Yang Y. D. Zhao and H. Ohkawara contributed equally to this study.

American Journal of Physiology Lung Cellular and Molecular Physiology 298 ( 1 ) L36-L44 2010年

Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca²⁺ signaling pathways in endothelial cells

SAKAMOTO, Nobuo*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; SAWAMURA, Tatsuya; SAKAMOTO, Takayuki*; INOUE, Nobutaka; SAITOH, Shu-ichi*; KAMIOKA, Masashi*; UEKITA, Hironori*; OHKAWARA, Hiroshi*; SUZUKI, Koji; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

Journal of Cellular Physiology 220 ( 3 ) 706 - 715 2009年

LOX-1-MT1-MMP axis is crucial for RhoA and Rac1 activation induced by oxidized low-density lipoprotein in endothelial cells

SUGIMOTO, Koichi*; ISHIBASHI, Toshiyuki*; SAWAMURA, Tatsuya; INOUE, Nobutaka; KAMIOKA, Masashi*; UEKITA, Hironori*; OHKAWARA, Hiroshi*; SAKAMOTO, Takayuki*; SAKAMOTO, Nobuo*; OKAMOTO, Yasuo; TAKUWA, Yoh; KAKINO, Akemi; FUJITA, Yoshiki; TANAKA, Takashi; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

Cardiovascular Research 84 ( 1 ) 127 - 136 2009年

Novel pathway of endothelin-1 and reactive oxygen species in coronary vasospasm with endothelial dysfunction

SAITOH, Shu-ichi*; MATSUMOTO, Ken*; KAMIOKA, Masashi*; OHKAWARA, Hiroshi*; KANESHIRO, Takashi*; ISHIBASHI, Toshiyuki*; MARUYAMA, Yukio*

Coronary Artery Disease 20 ( 6 ) 400 - 408 2009年

RhoA and Rac1 changes in the atherosclerotic lesions of WHHLMI rabbits

OHKAWARA, Hiroshi*; ISHIBASHI, Toshiyuki*; SHIOMI, Masashi; UEKITA, Hironori*; KAMIOKA, Masashi*; TAKUWA, Yoh; TERAMOTO, Tamio; MARUYAMA, Yukio; TAKEISHI, Yasuchika*

Journal of Atherosclerosis and Thrombosis 16 ( 6 ) 846 - 856 2009年

Bone marrow progenitor cells induce endothelial adherens junction integrity by sphingosine-1-phosphate-mediated Rac1 and Cdc42 signaling

ZHAO, Yidan; OHKAWARA, Hiroshi*; REHMAN, Jalees; WARY, Kishore; VOGEL, Stephen; MINSHALL, Richard; ZHAO, You-Yang; MALIK, Asrar

Circulation Research 105 ( 77 ) 696 - 704 2009年

RhoA-dependent PAI-1 gene expression induced in endothelial cells by monocyte adhesion mediates geranylgeranyl transferase I and Ca²⁺signaling

SAKAMOTO, Takayuki*; ISHIBASHI, Toshiyuki*; SUGIMOTO, Koichi*; SAKAMOTO, Nobuo*; OHKAWARA, Hiroshi*; NIINUMA, Miki*; NAGATA, Kenji*; KAMIOKA, Masashi*; SUGIMOTO, Naotoshi; WATANABE, Atai; KURABAYASHI, Masahiko; TAKUWA, Yoh; MARUYAMA, Yukio*

Atherosclerosis 193 ( 1 ) 44 - 54 2007年4月

Low serum ferritin levels as a clue to colonic cancer detection in two patients with coronary artery disease: a case report.

Yaoita H, Ohkawara H, Uekita H, Mitsugi M, Tajima H, Kaneko H, Hoshino Y, Otani S, Gotoh M, Maruyama Y.

Fukushima J Med Sci. 51 ( 2 ) 95 - 104 2005年12月

Endogenous NO blockade enhances tissue factor expression via increased Ca2+ influx through MCP-1 in endothelial cells by monocyte adhesion.

Sakamoto T, Ishibashi T, Sakamoto N, Sugimoto K, Egashira K, Ohkawara H, Nagata K, Yokoyama K, Kamioka M, Ichiki T, Sugimoto N, Kurabayashi M, Suzuki K, Takuwa Y, Maruyama Y.

Arterioscler Thromb Vasc Biol. 25 ( 9 ) 2005 - 2011 2005年9月

Thrombin-induced rapid geranylgeranylation of RhoA as an essential process for RhoA activation in endothelial cells.

Ohkawara H, Ishibashi T, Sakamoto T, Sugimoto K, Nagata K, Yokoyama K, Sakamoto N, Kamioka M, Matsuoka I, Fukuhara S, Sugimoto N, Takuwa Y, Maruyama Y.

J Biol Chem. 280 ( 11 ) 10182 - 10188 2005年3月

Integral role of RhoA activation in monocyte adhesion-triggered tissue factor expression in endothelial cells.

Ishibashi T, Sakamoto T, Ohkawara H, Nagata K, Sugimoto K, Sakurada S, Sugimoto N, Watanabe A, Yokoyama K, Sakamoto N, Kurabayashi M, Takuwa Y, Maruyama Y.

Arterioscler Thromb Vasc Biol. 23 ( 4 ) 681 - 687 2003年4月

Rho/Rho-kinase is involved in the synthesis of tissue factor in human monocytes

Nagata K, Ishibashi T, Sakamoto T, Ohkawara H, Shindo J, Yokoyama K, Sugimoto K, Sakurada S, Takuwa Y, Nakamura S, Teramoto T, Maruyama Y.

Atherosclerosis. 163 ( 1 ) 39 - 47 2002年7月

Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes.

Ishibashi T, Nagata K, Ohkawara H, Sakamoto T, Yokoyama K, Shindo J, Sugimoto K, Sakurada S, Takuwa Y, Teramoto T, Maruyama Y.

Biochim Biophys Acta. 1590 ( 1-3 ) 123 - 130 2002年6月

HMG-CoA reductase inhibitors suppress intracellular calcium mobilization and membrane current induced by lysophosphatidylcholine in endothelial cells.

Yokoyama K, Ishibashi T, Ohkawara H, Kimura J, Matsuoka I, Sakamoto T, Nagata K, Sugimoto K, Sakurada S, Maruyama Y.

Circulation. 105 ( 8 ) 962 - 967 2002年2月

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