Faculty Profiles - KONO Koji

Papers - KONO Koji

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Regenerative medicine for oesophageal reconstruction after cancer treatment

Kerm Sin Chian, Meng Fatt Leong, Koji Kono

Lancet Oncology. 16 ( 2 ) e84-92 2015.2

Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer

Kousaku Mimura, Takahiro Kamiya, Kensuke Shiraishi, Ley-Fang Kua, Asim Shabbir, Jimmy So, Wei-Peng Yong, Yoshiyuki Suzuki, Yuya Yoshimoto, Takashi Nakano, Hideki Fujii, Dario Campana and Koji Kono

International Journal of Cancer. 135 ( 6 ) 1390 - 1398 2014.9

A chimeric receptor that triggers antibody-dependent cell cytotoxicity against multiple tumors in T lymphocytes

Ko Kudo, Chihaya Imai, Paolo Lorenzini, Takahiro Kamiya, Koji Kono, Andrew Davidoff, Chng Wee Joo, and Dario Campana

Cancer Research. 74 ( 1 ) 93 - 103 2014.1

Inhibition of MAPK pathway can induce up-regulation of HLA class I without PD-L1-up-regulation in contrast to IFN-γtreatment

Kousaku Mimura, Ley-Fang KUA, Kensuke Shiraishi, Lim Kee Siang, Asim Shabbir, Mayumi Komachi, Yoshiyuki Suzuki, Takashi Nakano, Wei-Peng Yong, Jimmy So, and Koji Kono

Cancer Science. 105 ( 10 ) 1236 - 1244 2014.10

Anti-tumor immunity is fundamental to the therapeutic efficacy of irradiation

Yuya Yoshimoto, Yoshiyuki Suzuki, Kousaku Mimura, Ken Ando, Takahiro Oike, Hiro Sato, Noriyuki Okonogi, Takanori Maruyama, Shinichiro Izawa, Shin-ei Noda, Hideki Fujii, Koji Kono, Takashi Nakano

ProsOne. 9 ( 3 ) e92572 2014.3

Current status of cancer immunotherapy

Koji Kono

Journal of Stem Cell and Regenerative Medicine. 10 ( 1 ) 8 - 13 2014.4

Computed Tomography of the Thorax for Gastric Cancer Staging: Is it necessary?

CS Chong, Celene Ng, Asim Shabbir, Koji Kono, Jimmy So

Scandian Journal of Surgery. pii: 1457496915571400. 2015.2

Consensus guidelines for the detection of immunogenic cell death

Kepp O, Senovilla L, Vitale I,Koji Kono, et al

OncoImmunology. 3 ( 9 ) e955691 2014.10

Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable to X-ray irradiation

Yoshimoto Y, Oike T, Okonogi N, Suzuki Y, Ando K, Sato H, Noda SE, Isono M, Mimura K, Kono K, Nakano T

Journal of Radiation Research. 56 ( 3 ) 509 - 514 2015.3

A nationwide survey on the safety of cricothyrotomy: a multicenter retrospective study in Japan.

Booka E, Takeuchi H, Kikuchi H, Miura A, Kanda M, Kawaguchi Y, Hamai Y, Nasu M, Sato S, Inoue M, Okubo K, Ogawa R, Sato H, Yoshino S, Takebayashi K, Kono K, Toh Y, Katori Y.

Esophagus 22 ( 1 ) 19 - 26 2025.1

Impact of the Combination of Anamorelin and Rehabilitation on Functional and Nutritional Outcomes in Patients with Cancer Cachexia.

Hasegawa M, Sanmoto Y, Kono K

Nutr Cancer 77 ( 1 ) 86 - 92 2025

集学的治療により長期生存が得られた穿孔性S状結腸癌,同時性肝転移の1例

星野啓太, 藤田正太郎, 中島隆宏, 八島玲, 河野浩二

癌と化学療法 51 ( 13 ) 1393 - 1395 2024.12

憩室内に発生した早期S状結腸癌を腹腔鏡補助下に局所切除した1例

千田峻, 木口託見, 深井智司, 伊藤美郷, 芦澤舞, 小野澤寿志, 岡山洋和, 坂本渉, 齋藤元伸, 門馬智之, 河野浩二

癌と化学療法 51 ( 13 ) 1312 - 1314 2024.12

Prognostic factors of second-line nivolumab monotherapy for unresectable or metastatic esophageal cancer: a multi-institutional cohort study for 184 cases.

Sato S, Suzuki T, Chinen T, Yamaguchi H, Suzuki Y, Hokamura N, Saze Z, Kono K, Takahashi K, Yano F, Sato T, Kosaka T, Endo I, Ichikawa Y, Miyawaki Y, Sato H, Shimada H

Journal of gastroenterology 59 ( 11 ) 979 - 985 2024.11

Thoracoscopic and endoscopic cooperative surgery for esophageal gastrointestinal stromal tumor: a case report.

Kanoda R, Kikuchi T, Utsumi A, Mochizuki S, Matsuishi A, Kaneta A, Nirei A, Hanayama H, Saze Z, Hikichi T, Hashimoto Y, Kono K

Surgical case reports 10 ( 1 ) 237 - 237 2024.10（ ISSN:2198-7793 ）

Esophagectomy for esophageal cancer in patients with a history of total pharyngolaryngectomy: a Japanese nationwide retrospective cohort study.

Okamura A, Watanabe M, Okui J, Kuriyama K, Shiraishi O, Kurogochi T, Abe T, Sato H, Miyata H, Kawaguchi Y, Sato Y, Nagano H, Takeno S, Nakajima M, Matsuo K, Murakami K, Takebayashi K, Matsumoto S, Okumura T, Kakeji Y, Kono K, Oridate N, Toh Y, Takeuchi H, Katori Y; Joint Research between the Japan Broncho-esophagological Society and the Japan Esophageal Society

Esophagus 21 ( 4 ) 438 - 446 2024.10

Comparison of proton-based definitive chemoradiotherapy and surgery-based therapy for esophageal squamous cell carcinoma: a multi-center retrospective Japanese cohort study.

Ogawa K, Ishikawa H, Toyozumi T, Noma K, Kono K, Hojo H, Tamamura H, Azami Y, Ishida T, Nabeya Y, Iwata H, Araya M, Tokumaru S, Maruo K, Oda T, Matsubara H

Esophagus 21 ( 4 ) 484 - 494 2024.10

Outcome research on esophagectomy analyzed using nationwide databases in Japan: evidences generated from real-world data.

Kakeji Y, Yamamoto H, Watanabe M, Kono K, Ueno H, Doki Y, Kitagawa Y, Takeuchi H, Shirabe K, Seto Y

Esophagus 21 ( 4 ) 411 - 418 2024.10

Correction: Comparison of proton-based Definitive chemoradiotherapy and surgery-based therapy for esophageal squamous cell carcinoma: a multi-center retrospective Japanese cohort study.

Ogawa K, Ishikawa H, Toyozumi T, Noma K, Kono K, Hojo H, Tamamura H, Azami Y, Ishida T, Nabeya Y, Iwata H, Araya M, Tokumaru S, Maruo K, Oda T, Matsubara H

Esophagus 21 ( 4 ) 495 - 495 2024.10

Analysis of operative duration of image-guided brachytherapy for cervical cancer.

Takagawa Y, Machida M, Seto I, Komori S, Sato H, Endo H, Midorikawa H, Kato T, Murakami M, Honda M, Kono K

Strahlentherapie und Onkologie 2024.9

High levels of tumor cell-intrinsic STING signaling are associated with increased infiltration of CD8(+) T cells in dMMR/MSI-H gastric cancer.

Kanoda R, Nakajima S, Fukai S, Saito M, Saito K, Suzuki H, Kikuchi T, Nirei A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K

Scientific reports 14 ( 1 ) 20859 2024.9

Oncofetal IGF2BP3-mediated control of microRNA structural diversity in the malignancy of early-stage lung adenocarcinoma.

Fujiwara Y, Takahashi RU, Saito M, Umakoshi M, Shimada Y, Koyama K, Yatabe Y, Watanabe SI, Koyota S, Minamiya Y, Tahara H, Kono K, Shiraishi K, Kohno T, Goto A, Tsuchiya N

Proc Natl Acad Sci U S A 121 ( 36 ) 2024.9

胃癌におけるHER2シグナルを介した腫瘍微小環境の制御　HER2過剰発現の腫瘍内不均一性を呈する胃癌症例からの検討

中嶋正太郎, 深井智司, 金田晃尚, 圓谷秀哲, 松石彬, 岡山洋和, 齋藤元伸, 三村耕作, 坂本渉, 佐瀬善一郎, 門馬智之, 河野浩二

癌と化学療法 51 ( 9 ) 903 - 905 2024.9

Appropriate timing for the removal of urinary catheters in gastrointestinal surgery with epidural anesthesia: a randomized controlled trial.

Miyakawa T, Honda M, Kawamura H, Yamamoto R, Toshiyama S, Mashiko R, Kakinuma H, Hori S, Nakao E, Todate Y, Takano Y, Kono K

Langenbecks Arch Surg 409 ( 1 ) 265 - 265 2024.8

The impact of CLDN18.2 expression on effector cells mediating antibody-dependent cellular cytotoxicity in gastric cancer.

Matsuishi A, Nakajima S, Saito M, Saito K, Fukai S, Tsumuraya H, Kanoda R, Kikuchi T, Nirei A, Kaneta A, Okayama H, Mimura K, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K

Scientific reports 14 ( 1 ) 17916 2024.8

Cardiac tamponade caused by a ruptured coronary aneurysm treated with open-chest hemostasis after esophageal cancer surgery: a case report.

Hasegawa M, Kikuchi T, Yago H, Mitsui D, Matsuishi A, Tsumuraya H, Kaneta A, Matsuida H, Nirei A, Hanayama H, Saze Z, Takase S, Kono K

Journal of surgical case reports 2024 ( 8 ) rjae555 2024.8

腹腔鏡下に切除した腫瘍内感染を伴う胃gastrointestinal stromal tumorの1例

叶多諒, 花山寛之, 松石彬, 丸山裕也, 目黒啓予, 松井田元, 金田晃尚, 楡井東, 菊池智宏, 佐瀬善一郎, 橋本優子, 河野浩二

福島医学雑誌 74 ( 2 ) 41 - 46 2024.8（ ISSN:0016-2582 ）

The real-world data of immune-checkpoint inhibitor combination therapy for unresectable or metastatic esophageal cancer: a multi-institutional cohort study.

Sato S, Ssuzuki T, Chinen T, Yamaguchi H, Suzuki Y, Hokamura N, Saze Z, Kono K, Takahashi K, Yano F, Kunisaki C, Kosaka T, Endo I, Ichikawa Y, Miyawaki Y, Sato H, Shimada H

International journal of clinical oncology 29 ( 7 ) 994 - 1001 2024.7

Tumor Infiltrating Effector Regulatory T Cells Express VEGF Receptor 2 in Patients With Colorectal Cancer.

Tsumuraya H, Mimura K, Nakajima S, Hanayama H, Matsuishi A, Okayama H, Fukai S, Ito M, Ashizawa M, Chida S, Onozawa H, Sakamoto W, Saito M, Saze Z, Momma T, Kono K

Anticancer research 44 ( 7 ) 2933 - 2941 2024.7

Biomarker-oriented chemo-immunotherapy for advanced gastric cancer.

Kono K, Nakajima S, Mimura K

Int J Clin Oncol 36 ( 3 ) 865 - 872 2024.7

The ratio of intratumoral CD15+ neutrophils to CD8+ lymphocytes predicts recurrence in patients with gastric cancer after curative resection.

Watanabe J, Kimura T, Saze Z, Sato N, Kofunato Y, Ishigame T, Okada R, Kenjo A, Kono K, Marubashi S

Cancer Rep (Hoboken) 7 ( 6 ) e2099 2024.6

Evaluation of the prognostic impact of pathologic tumor regression grade on patients with colorectal cancer after preoperative chemoradiotherapy.

Nakao E, Honda M, Uesugi N, Osakabe M, Sato A, Todate Y, Yaegashi M, Takano Y, Sasaki A, Kono K, Sugai T

Journal of Surgical Oncology 129 ( 8 ) 1521 - 1533 2024.6

Proton beam reirradiation for locally recurrent rectal cancer patients with prior pelvic irradiation.

Takagawa Y, Suzuki M, Seto I, Azami Y, Machida M, Takayama K, Sulaiman NS, Nakasato T, Kikuchi Y, Murakami M, Honda M, Teranishi Y, Kono K

Journal of radiation research 65 ( 3 ) 379 - 386 2024.5

TIM-3 Expression on Dendritic Cells in Colorectal Cancer.

Sakuma M, Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Fukai S, Tsumuraya H, Onozawa H, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K

Cancers 16 ( 10 ) 1888 - 1888 2024.5（ ISSN:2072-6694 ）

Radiological Cutoff Values for Diagnosis of Lymph Node Metastasis in Colorectal Cancer With Multilevel Analysis.

Todate Y, Takada T, Honda M, Miyakawa T, Yamamoto R, Toshiyama S, Nakao E, Mashiko R, Kakinuma H, Kawamura H, Yamaguchi H, Takagawa Y, Kono K

Cancer Diagn Progn 4 ( 3 ) 333 - 339 2024.5

TGFβ-Responsive Stromal Activation Occurs Early in Serrated Colorectal Carcinogenesis.

Tsumuraya H, Okayama H, Katagata M, Matsuishi A, Fukai S, Ito M, Sakamoto W, Saito M, Momma T, Nakajima S, Mimura K, Kono K

International journal of molecular sciences 25 ( 9 ) 4626 - 4626 2024.4

基調講演食道癌における治療介在による腫瘍微小環境リモデリング

河野浩二

日本気管食道科学会会報 75 ( 2 ) 139 - 139 2024.4

The tumor cell-intrinsic cGAS-STING pathway is associated with the high density of CD8+ T cells after chemotherapy in esophageal squamous cell carcinoma.

Matsuishi A, Nakajima S, Kaneta A, Saito K, Fukai S, Sakuma M, Tsumuraya H, Okayama H, Saito M, Mimura K, Nirei A, Kikuchi T, Hanayama H, Saze Z, Sakamoto W, Momma T, Kono K

Esophagus : official journal of the Japan Esophageal Society 21 ( 2 ) 165 - 175 2024.4（ ISSN:1612-9059 ）

手術手技　Gambee縫合を用いたロボット支援上川法再建　トルネード法による運針手技

佐瀬善一郎, 河野浩二

手術 78 ( 5 ) 839 - 846 2024.4

Endosomal protein expression of γ1-adaptin is associated with tumor growth activity and relapse-free survival in breast cancer.

Hoshi N, Uemura T, Tachibana K, Abe S, Murakami-Nishimagi Y, Okano M, Noda M, Saito K, Kono K, Ohtake T, Waguri S

Breast Cancer 31 ( 2 ) 305 - 316 2024.3

Prognostic impact and survival outcomes of colon perforation in patients with metastatic colorectal cancer: a multicenter retrospective cohort study.

Nakao E, Kawamura H, Honda M, Takano Y, Kinuta S, Kamiga T, Yamazaki S, Muto A, Shiraso S, Yamashita N, Iwao T, Kono K, Konno S

International journal of clinical oncology 29 ( 2 ) 179 - 187 2024.2

山間部の中核病院,がん治療センター開設365日(解説)

柴田昌彦, 成田尚也, 大野史絵, 伊藤絵美, 矢澤貴, 長谷川翔, 井上典夫, 持田謙介, 前田佳一郎, 南嘉輝, 遠藤俊吾, 高田信, 鈴木義行, 河野浩二, 竹之下誠一

癌と化学療法 51 ( 2 ) 153 - 158 2024.2

Recurrence-free survival as a surrogate endpoint for overall survival after neoadjuvant chemotherapy and surgery for oesophageal squamous cell carcinoma.

Okui J, Nagashima K, Matsuda S, Sato Y, Okamura A, Kawakubo H, Muto M, Kakeji Y, Kono K, Takeuchi H, Watanabe M, Doki Y, Bamba T, Fukuda T, Fujiwara H, Sato S, Noma K, Miyata H, Fujita T, Kitagawa Y

British journal of surgery 111 ( 2 ) znae038 2024.1

Combination of oligo-fractionated irradiation with nivolumab can induce immune modulation in gastric cancer.

Mimura K, Ogata T, Nguyen PHD, Roy S, Kared H, Yuan YC, Fehlings M, Yoshimoto Y, Yoshida D, Nakajima S, Sato H, Machida N, Yamada T, Watanabe Y, Tamaki T, Fujikawa H, Inokuchi Y, Hayase S, Hanayama H, Saze Z, Katoh H, Takahashi F, Oshima T, Goel A, Nardin A, Suzuki Y, Kono K

Journal for immunotherapy of cancer 12 ( 1 ) e008385 2024.1

Outcomes of patients with esophageal squamous cell carcinoma who achieved a pathological complete response in the primary lesion by neoadjuvant treatment: a Japanese nationwide cohort study.

Okamura A, Watanabe M, Okui J, Matsuda S, Takemura R, Kawakubo H, Kakeji Y, Kono K, Kitagawa Y, Takeuchi H

Esophagus 21 ( 1 ) 2 - 10 2024.1

化学療法に抵抗性を示した再発病変に対してPembrolizumabが奏効し長期生存を得たMSI-High S状結腸癌の1例

圓谷秀哲, 金田晃尚, 藤田正太郎, 林下宗平, 望月翔太朗, 鈴木博也, 滝口千晶, 松石彬, 丸山裕也, 叶多諒, 佐久間芽衣, 坂本渉, 門馬智之, 佐瀬善一郎, 河野浩二

癌と化学療法 50 ( 13 ) 1742 - 1744 2023.12

進行胃癌に対するラムシルマブ＋ナブパクリタキセル療法中に十二指腸穿孔を生じた１例

花山寛之，鈴木博也，望月翔太朗，林下宗平，松石彬，叶多諒，丸山裕也，金田晃尚，菊池智宏，楡井東，多田武志，佐瀬善一郎，河野浩二

癌と化学療法 50 ( 13 ) 1636 - 1637 2023.12

放射線治療による腫瘍細胞内cGAS-STING経路を介した食道扁平上皮癌微小環境の変化

中嶋正太郎, 三村耕作, 金田晃尚, 片方雅紀, 岡山洋和, 齋藤元伸, 佐瀬善一郎, 花山寛之, 多田武志, 門馬智之, 河野浩二

癌と化学療法 50 ( 10 ) 1099 - 1101 2023.10

Thoracic and cardiovascular surgeries in Japan during 2019 : Annual report by the Japanese Association for Thoracic Surgery

Committee for Scientific Affairs, The Japanese Association for Thoracic Surgery; Minatoya K, Sato Y, Toh Y, Abe T, Endo S, Hirata Y, Ishida M, Iwata H, Kamei T, Kawaharada N, Kawamoto S, Kohno K, Kumamaru H, Matsumiya G, Motomura N, Nakahara R, Okada M, Saji H, Saito A, Shimizu H, Suzuki K, Takemura H, Taketani T, Takeuchi H, Tatsuishi W, Yamamoto H, Yasuda T, Watanabe M, Yoshimura N, Tsuchida M, Sawa Y

Gen Thorac Cardiovasc Surg 71 ( 10 ) 595 - 628 2023.10

5.免疫チェックポイント阻害薬の将来

河野浩二

消化器がん免疫療法の現在　がん治療の転換点に立つ 28 - 34 2023.9

はじめに

柴田昌彦, 河野浩二

消化器がん免疫療法の現在　がん治療の転換点に立つ 4 - 5 2023.9

第2章消化器腫瘍外科の立場から　1.上部・下部消化管

佐瀬善一郎, 河野浩二

Oncologic Emergency A to Z 12 - 17 2023.9

食道癌術後に左総頸動脈食道胃管吻合部瘻を発症し心肺停止に至ったが救命しえた1例

佐藤孝洋, 佐瀬善一郎, 滝口千晶, 叶多諒, 佐久間芽衣, 圓谷秀哲, 片方雅紀, 深井智司, 三村耕作, 河野浩二　

日本消化器外科学会雑誌 56 ( 9 ) 471 - 478 2023.9

本ガイドブックの使い方

河野浩二, 三村耕作

よくわかるがん免疫療法ガイドブック　患者さんとご家族のために第2版 1 - 2 2023.9

序文

河野浩二

よくわかるがん免疫療法ガイドブック　患者さんとご家族のために第2版 3 2023.9

Down-regulation of stimulator of interferon genes (STING) expression and CD8(+) T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.

Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K

Gastric cancer 26 ( 6 ) 878 - 890 2023.8

A Potential Biomarker of Dynamic Change in Peripheral CD45RA(-)CD27(+)CD127(+) Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma.

Sakuma M, Mimura K, Nakajima S, Kaneta A, Kikuchi T, Nirei A, Tada T, Hanayama H, Okayama H, Sakamoto W, Saito M, Momma T, Saze Z, Kono K

Cancers 15 ( 14 ) 3641 2023.7（ ISSN:2072-6694 ）

Anti-PD-1 monoclonal antibody-resistant esophageal squamous cell carcinoma showing the abscopal effect: A case report with T-cell receptor/B-cell receptor repertoire analysis.

Takehara Y, Mimura K, Suzuki Y, Watanabe Y, Yoshimoto Y, Saze Z, Sato H, Tamaki T, Kono K.

Cancer Reports 6 ( 7 ) e1832 2023.7

The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8(+) T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer.

Nakajima S, Kaneta A, Okayama H, Saito K, Kikuchi T, Endo E, Matsumoto T, Fukai S, Sakuma M, Sato T, Mimura K, Saito M, Saze Z, Sakamoto W, Onozawa H, Momma T, Kono K

Cancers 15 ( 10 ) 2826 2023.5（ ISSN:2072-6694 ）

胃がんにおける原発巣に近接する三次リンパ組織の免疫学的役割

河野浩二

GICancer Cutting Edege 4 ( 3 ) 7 2023.5

腸管切除を行わずに救命し得た消化管アミロイドーシスに非閉塞性腸管虚血を併発した1例

深井智司，早瀬傑，大関篤，丸山裕也，遠藤久仁，伊藤泰輔，石井芳正，河野浩二

福島医学雑誌 73 ( 1 ) 7 - 11 2023.4

Radiation-Induced Remodeling of the Tumor Microenvironment Through Tumor Cell-Intrinsic Expression of cGAS-STING in Esophageal Squamous Cell Carcinoma.

Nakajima S, Mimura K, Kaneta A, Saito K, Katagata M, Okayama H, Saito M, Saze Z, Watanabe Y, Hanayama H, Tada T, Sakamoto W, Momma T, Ohira H, Kono K

International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2023.3（ ISSN:0360-3016 ）

M2 tumor-associated macrophages resist to oxidative stress through heme oxygenase-1 in the colorectal cancer tumor microenvironment.

Ito M, Mimura K, Nakajima S, Okayama H, Saito K, Nakajima T, Kikuchi T, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Kono K

Cancer immunology, immunotherapy : CII 72 ( 7 ) 2233 - 2244 2023.3（ ISSN:0340-7004 ）

Clinical Features and Survival of Young Adults with Stage IV Gastric Cancer: a Japanese Population-Based Study.

Yamamoto R, Honda M, Kawamura H, Kobayashi H, Takiguchi K, Muto A, Yamazaki S, Teranishi Y, Shiraso S, Kono K, Hori S, Kamiga T, Iwao T, Yamashita N

Journal of gastrointestinal cancer 54 ( 1 ) 56 - 61 2023.3（ ISSN:1941-6628 ）

アブスコパル効果を示唆する腫瘍縮小を示した再発胃癌症例の検討

中島隆宏, 桑原公亀, 島貫公義, 井上典夫, 河野浩二

癌と化学療法 50 ( 3 ) 399 - 400 2023.3

Clinical Features and Survival of Young Adults with Stage IV Gastric Cancer: a Japanese Population-Based Study.

Yamamoto R, Honda M, Kawamura H, Kobayashi H, Takiguchi K, Muto A, Yamazaki S, Teranishi Y, Shiraso S, Kono K, Hori S, Kamiga T, Iwao T, Yamashita N

Journal of gastrointest cancer 54 ( 1 ) 56 - 61 2023.3

ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.

Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 3 ) 379 - 392 2023.2（ ISSN:1436-3291 ）

Systemic inflammation score as a preoperative prognostic factor for patients with pT2-T4 resectable gastric cancer: a retrospective study.

Matsumoto T, Ohki S, Kaneta A, Matsuishi A, Maruyama Y, Yamada L, Tada T, Hanayama H, Watanabe Y, Hayase S, Okayama H, Sakamoto W, Momma T, Saze Z, Kono K

BMC surgery 23 ( 1 ) 8 2023.1

第17章　移植免疫

河野浩二

分子細胞免疫学原著第10版アバス-リックマン-ピレ 411 - 435 2023.1

Comprehensive registry of esophageal cancer in Japan, 2015

Watanabe M, Toh Y, Ishihara R, Kono K, Matsubara H, Miyazaki T, Morita M, Murakami K, Muro K, Numasaki H, Oyama T, Saeki H, Tanaka K, Tsushima T, Ueno M, Uno T, Yoshio T, Usune S, Takahashi A, Miyata H; Registration Committee for Esophageal Cancer of the Japan Esophageal Society

Esophagus 20 ( 1 ) 1 - 28 2023.1

Phase I/II clinical trial of nivolumab in combination with oligo-fractionated irradiation for unresectable advanced or recurrent gastric cancer.

Mimura K, Ogata T, Yoshimoto Y, Yoshida D, Nakajima S, Sato H, Machida N, Yamada T, Watanabe Y, Tamaki T, Fujikawa H, Inokuchi Y, Hayase S, Hanayama H, Saze Z, Katoh H, Takahashi F, Oshima T, Suzuki Y, Kono K

Cancer medicine 3 ( 1 ) 111 2023

Prognostic impact of endoscopic response evaluation after neoadjuvant chemotherapy for esophageal squamous cell carcinoma: a nationwide validation study.

Matsuda S, Kitagawa Y, Okui J, Okamura A, Kawakubo H, Takemura R, Kono K, Muto M, Kakeji Y, Takeuchi H, Watanabe M, Doki Y

Esophagus 20 ( 3 ) 455 - 464 2023

TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer.

Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, Fukai S, Endo E, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K

Cancers 15 ( 20 ) 4943 2023

Impact of the COVID-19 pandemic on the performance of endoscopy in the Tohoku region of Japan.

Iijima K, Matsuhashi T, Shimodaira Y, Mikami T, Yoshimura T, Yanai S, Kudara N, Tsuji T, Matsushita HO, Watanabe H, Koike T, Kato K, Abe Y, Shirahata N, Hikichi T, Katakura K, Kono K, Sakuraba H, Ueno Y, Ohira H, Masamune A, Matsumoto T, Fukuda S; Japan Gastroenterological Endoscopy Society‐Tohoku.

DEN Open 4 ( 1 ) e249 2023

Immunological Responses Associated With Neoadjuvant Therapy in the Tumor Microenvironment of Esophageal Squamous Cell Carcinoma.

Takehara Y, Tamaki T, Mimura K, Saito K, Neupane P, Tada T, Watanabe Y, Hayase S, Saze Z, Yoshimoto Y, Sato H, Kono K, Suzuki Y

Anticancer research 43 ( 10 ) 4691 - 4700 2023

Esophageal cancer practice guidelines 2022 edited by the Japan esophageal society: part 1.

Kitagawa Y, Ishihara R, Ishikawa H, Ito Y, Oyama T, Oyama T, Kato K, Kato H, Kawakubo H, Kawachi H, Kuribayashi S, Kono K, Kojima T, Takeuchi H, Tsushima T, Toh Y, Nemoto K, Booka E, Makino T, Matsuda S, Matsubara H, Mano M, Minashi K, Miyazaki T, Muto M, Yamaji T, Yamatsuji T, Yoshida M

Esophagus 20 ( 3 ) 343 - 372 2023

Esophageal cancer practice guidelines 2022 edited by the Japan Esophageal Society: part 2.

Esophagus 20 ( 3 ) 373 - 389 2023

Concurrent chemoradiotherapy using proton beams can reduce cardiopulmonary morbidity in esophageal cancer patients: a systematic review.

Nonaka T, Kawashiro S, Ishikawa H, Ito Y, Nemoto K, Ishihara R, Oyama T, Oyama T, Kato K, Kato H, Kawakubo H, Kawachi H, Kuribayashi S, Kono K, Kojima T, Takeuchi H, Tsushima T, Toh Y, Booka E, Makino T, Matsuda S, Matsubara H, Mano M, Minashi K, Miyazaki T, Muto M, Yamaji T, Yamatsuji T, Yoshida M, Kitagawa Y; Esophageal Cancer Practice Guidelines Preparation Committee

Esophagus 20 ( 4 ) 605 - 616 2023

cGAS-STING経路を標的とした大腸癌の新規治療戦力の可能性

中嶋正太郎, 金田晃尚, 河野浩二

癌と化学療法 50 ( 9 ) 950 - 954 2023

【世界各国における外科医の教育と地位】シンガポールにおける外科医について

河野浩二

外科 85 ( 7 ) 828 - 833 2023

Clinical outcomes of laparoscopic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumor.

Hanayama H, Katagata M, Sato T, Nakano H, Matsumoto T, Tada T, Watanabe Y, Hayase S, Okayama H, Momma T, Kato T, Hashimoto M, Nakamura J, Hikichi T, Saze Z, Kono K

Fukushima journal of medical science 68 ( 3 ) 169 - 174 2022.12

Inhibiting VEGF in cancer immunotherapy.

Shibata M, Kono K, Takenoshita S

Clin Immunol Comm. 2 12 - 16 2022.12

Metabolic Impact of Immune-Suppressor Cells in Cancer Patients.

Shibata M, Inukai A, Yoshimori D, Ashizawa M, Nakajima T, Takada M, Yazawa T, Mimura K, Inoue N, Watanabe T, Tachibana K, Muto S, Kono K, Endo S, Takenoshita S

Journal of Surgical Research 5 ( 1 ) 134 - 144 2022.12

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more.

Shibata M, Nanno K, Yoshimori D, Nakajima T, Takada M, Yazawa T, Mimura K, Inoue N, Watanabe T, Tachibana K, Muto S, Momma T, Suzuki Y, Kono K, Endo S, Takenoshita S

Oncotarget 13 1273 - 1285 2022.11

【がん・感染症免疫と腸内細菌の関係を知る】(Part1)がん免疫　大腸がんにおける腸内細菌叢と腫瘍浸潤免疫担当細胞の関連を考える

菊池智宏, 河野浩二

Microbiome Science 1 ( 2 ) 80 - 85 2022.10

dMMR/MSI-H大腸癌におけるcGAS-STING経路の発現

金田晃尚, 中嶋正太郎, 三村耕作, 河野浩二

癌と化学療法 49 ( 10 ) 1130 - 1132 2022.10

【複合がん免疫療法】食道扁平上皮癌における抗PD-1療法と放射線治療を用いた複合がん免疫療法の開発

三村耕作, 河野浩二

癌と化学療法 49 ( 9 ) 914 - 916 2022.9

Immune escape mechanism behind resistance to anti-PD-1 therapy in gastrointestinal tract metastasis in malignant melanoma patients with multiple metastases.

Ito M, Mimura K, Nakajima S, Saito K, Min AKT, Okayama H, Saito M, Momma T, Saze Z, Ohtsuka M, Yamamoto T, Kono K

Cancer Immunology, Immunotherapy 71 ( 9 ) 2293 - 2300 2022.9

Short-term outcomes of neoadjuvant chemotherapy with capecitabine plus oxaliplatin for patients with locally advanced rectal cancer followed by total or tumor-specific mesorectal excision with or without lateral pelvic lymph node dissection.

Sakamoto W, Kanke Y, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Kono K

Fukushima journal of medical science 68 ( 2 ) 89 - 95 2022.8（ ISSN:0016-2590 ）

Preoperative bacterial culture can predict severe pneumonia in patients receiving esophagectomy.

Kaneta A, Sato T, Nakano H, Matsumoto T, Tada T, Watanabe Y, Hanayama H, Hayase S, Saze Z, Kono K

Fukushima journal of medical science 68 ( 2 ) 109 - 116 2022.8（ ISSN:0016-2590 ）

Two cases of pancreaticoduodenal aneurysm with median arcuate ligament syndrome treated with coil embolization and median arcuate ligament incision.

Endo Y, Sekino H, Ishii S, Okada R, Kofunato Y, Nakano H, Watanabe Y, Marubashi S, Kono K, Ito H

Radiol Case Rep 17 ( 10 ) 3663 - 3668 2022.8

Laparoscopic total gastrectomy performed for juvenile polyposis of the stomach: A case report.

Ito M, Onozawa H, Saito M, Ami H, Ohki S, Koyama Y, Kono K

International journal of surgery case reports 97 107368 2022.8

Prognostic Role of Carcinoembryonic Antigen and Carbohydrate Antigen 19-9 in Stage IV Colorectal Cancer.

Kawamura H, Honda M, Takano Y, Kinuta S, Kamiga T, Saji S, Kono K

Anticancer research 42 ( 8 ) 3921 - 3928 2022.8

Endoscopic imaging modalities for diagnosing the invasion depth of superficial esophageal squamous cell carcinoma: a systematic review.

Inoue T, Ishihara R, Shibata T, Suzuki K, Kitagawa Y, Miyazaki T, Yamaji T, Nemoto K, Oyama T, Muto M, Takeuchi H, Toh Y, Matsubara H, Mano M, Kono K, Kato K, Yoshida M, Kawakubo H, Booka E, Yamatsuji T, Kato H, Ito Y, Ishikawa H, Tsushima T, Kawachi H, Oyama T, Kojima T, Kuribayashi S, Makino T, Matsuda S, Doki Y, Esophageal Cancer Practice Guidelines Preparation Committee.

Esophagus : official journal of the Japan Esophageal Society 19 ( 3 ) 375 - 383 2022.7（ ISSN:1612-9059 ）

急性虫垂炎を合併した虫垂原発Burkitt lymphomaの1例

片方雅紀, 藤田正太郎, 青砥慶太, 伊藤泰輔, 石井芳正, 河野浩二

日本臨床外科学会雑誌 83 ( 7 ) 1312 - 1317 2022.7（ ISSN:1345-2843 ）

小腸原発髄外性形質細胞腫の1例

岩田亜弓, 深井智司, 菅家康之, 藤田正太郎, 門馬智之, 河野浩二

日本臨床外科学会雑誌 83 ( 7 ) 1296 - 1300 2022.7（ ISSN:1345-2843 ）

Role of the cGAS-STING pathway in regulating the tumor-immune microenvironment in dMMR/MSI colorectal cancer.

Kaneta A, Nakajima S, Okayama H, Matsumoto T, Saito K, Kikuchi T, Endo E, Ito M, Mimura K, Kanke Y, Saito M, Saze Z, Fujita S, Sakamoto W, Onozawa H, Momma T, Ohki S, Kono K

Cancer Immunology, Immunotherapy 71 ( 11 ) 2765 - 2776 2022.4（ ISSN:0340-7004 ）

SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer.

Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K

British journal of cancer 126 ( 6 ) 917 - 926 2022.4（ ISSN:0007-0920 ）

SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer.

Matsumoto T, Okayama H, Nakajima S, Saito K, Ito M, Kaneta A, Kanke Y, Onozawa H, Hayase S, Fujita S, Sakamoto W, Saito M, Seze Z, Momma T, Mimura K, Kono K

British journal of cancer 126 ( 6 ) 917 - 926 2022.4

A rare case of recurrent ovarian cancer with <i>TPM3-NTRK1</i> gene rearrangement: A case report.

Endo Y, Watanabe T, Saito M, Saito K, Suzuki R, Sano H, Natori Y, Sasaki E, Ueda M, Kamo N, Furukawa S, Soeda S, Kono K, Saji S, Fujimori K

Molecular and clinical oncology 16 ( 4 ) 90 2022.4（ ISSN:2049-9450 ）

臨床編3章治療効果の評価, 診断　5.バイオマーカー

伊藤美郷, 河野浩二

がん免疫ペディア　腫瘍免疫学・がん免疫療法の全てをまるごと理解！ 83 - 85 2022.3

Incidence of upper extremity deep vein thrombosis in the retrosternal reconstruction after esophagectomy.

Yamada L, Saito M, Suzuki H, Mochizuki S, Endo E, Kase K, Ito M, Nakano H, Yamauchi N, Matsumoto T, Kaneta A, Kanke Y, Onozawa H, Hanayama H, Okayama H, Fujita S, Sakamoto W, Watanabe Y, Hayase S, Saze Z, Momma T, Ohki S, Kono K

BMC surgery 22 ( 1 ) 91 2022.3

Nivolumab Combination Therapy in Advanced Esophageal Squamous-Cell Carcinoma

Doki Y, Ajani JA, Kato K, Xu J, Wyrwicz L, Motoyama S, Ogata T, Kawakami H, Hsu CH, Adenis A, El Hajbi F, Di Bartolomeo M, Braghiroli MI, Holtved E, Ostoich SA, Kim HR, Ueno M, Mansoor W, Yang WC, Liu T, Bridgewater J, Makino T, Xynos I, Liu X, Lei M, Kondo K, Patel A, Gricar J, Chau I, Kitagawa Y; CheckMate 648 Trial Investigators（Kono K）

386 ( 5 ) 449 - 462 2022.2

ステントグラフト内挿術後に三期的食道再建術を行った大動脈食道瘻の1例

仲野宏, 花山寛之, 佐瀬善一郎, 河野浩二

日本臨床外科学会雑誌 83 ( 2 ) 314 - 319 2022.2（ ISSN:1345-2843 ）

マイクロRNAによるPD-L1の制御機構 -The Best of the AACR Journals-

河野浩二, 岡山洋和, 芦澤舞

光が丘 51 62 - 63 2022.2

連載　腫瘍免疫 Up-To-Date　第3回放射線療法とがん免疫

河野浩二

GI Cancer Cutting Edge 3 ( 3 ) 4 - 5 2022.2

Immune escape mechanism behind resistance to anti-PD-1 therapy in gastrointestinal tract metastasis in malignant melanoma patients with multiple metastases.

Ito M, Mimura K, Nakajima S, Saito K, Min AKT, Okayama H, Saito M, Momma T, Saze Z, Ohtsuka M, Yamamoto T, Kono K

Cancer immunology, immunotherapy : CII 2022.1（ ISSN:0340-7004 ）

Clinical impact of gastrectomy for gastric cancer patients with positive lavage cytology without gross peritoneal dissemination.

Kobayashi H, Honda M, Kawamura H, Takiguchi K, Muto A, Yamazaki S, Teranishi Y, Shiraso S, Kono K, Hori S, Kamiga T, Iwao T, Yamashita N

Journal of surgical oncology 125 ( 4 ) 615 - 620 2022.1（ ISSN:0022-4790 ）

Comprehensive registry of esophageal cancer in Japan, 2014.

Watanabe M, Toh Y, Ishihara R, Kono K, Matsubara H, Murakami K, Muro K, Numasaki H, Oyama T, Ozawa S, Saeki H, Tanaka K, Tsushima T, Ueno M, Uno T, Yoshio T, Usune S, Takahashi A, Miyata H; Registration Committee for Esophageal Cancer of the Japan Esophageal Society

Esophagus : official journal of the Japan Esophageal Society 19 ( 1 ) 1 - 26 2022.1（ ISSN:1612-9059 ）

The potential for reducing alcohol consumption to prevent esophageal cancer morbidity in Asian heavy drinkers: a systematic review and meta-analysis.

Kubo Y, Kitagawa Y, Miyazaki T, Sohda M, Yamaji T, Sakai M, Saeki H, Nemoto K, Oyama T, Muto M, Takeuchi H, Toh Y, Matsubara H, Mano M, Kono K, Kato K, Yoshida M, Kawakubo H, Booka E, Yamatsuji T, Kato H, Ito Y, Ishikawa H, Ishihara R, Tsushima T, Kawachi H, Oyama T, Kojima T, Kuribayashi S, Makino T, Matsuda S, Doki Y; Esophageal Cancer Practice Guidelines Preparation Committee.

Esophagus : official journal of the Japan Esophageal Society 19 ( 1 ) 39 - 46 2022.1（ ISSN:1612-9059 ）

Fruit and vegetable consumption and risk of esophageal cancer in the Asian region: a systematic review and meta-analysis.

Sakai M, Kitagawa Y, Saeki H, Miyazaki T, Yamaji T, Nemoto K, Oyama T, Muto M, Takeuchi H, Toh Y, Matsubara H, Mano M, Kono K, Kato K, Yoshida M, Kawakubo H, Booka E, Yamatsuji T, Kato H, Ito Y, Ishikawa H, Ishihara R, Tsushima T, Kawachi H, Oyama T, Kojima T, Kuribayashi S, Makino T, Matsuda S, Sohda M, Kubo Y, Doki Y; Esophageal Cancer Practice Guidelines Preparation Committee.

Esophagus : official journal of the Japan Esophageal Society 19 ( 1 ) 27 - 38 2022.1（ ISSN:1612-9059 ）

The potential for reducing alcohol consumption to prevent esophageal cancer morbidity in Asian heavy drinkers: a systematic review and meta-analysis.

Kubo Yuto, Kitagawa Yuko, Miyazaki Tatsuya, Sohda Makoto, Yamaji Taiki, Sakai Makoto, Saeki Hiroshi, Nemoto Kenji, Oyama Tsuneo, Muto Manabu, Takeuchi Hiroya, Toh Yasushi, Matsubara Hisahiro, Mano Masayuki, Kono Koji, Kato Ken, Yoshida Masahiro, Kawakubo Hirofumi, Booka Eisuke, Yamatsuji Tomoki, Kato Hiroyuki, Ito Yoshinori, Ishikawa Hitoshi, Ishihara Ryu, Tsushima Takahiro, Kawachi Hiroshi, Oyama Takashi, Kojima Takashi, Kuribayashi Shiko, Makino Tomoki, Matsuda Satoru, Doki Yuichiro

Esophagus 19 ( 1 ) 39 - 46 2022.1（ ISSN:1612-9059 ）

Fruit and vegetable consumption and risk of esophageal cancer in the Asian region: a systematic review and meta-analysis.

Sakai Makoto, Kitagawa Yuko, Saeki Hiroshi, Miyazaki Tatsuya, Yamaji Taiki, Nemoto Kenji, Oyama Tsuneo, Muto Manabu, Takeuchi Hiroya, Toh Yasushi, Matsubara Hisahiro, Mano Masayuki, Kono Koji, Kato Ken, Yoshida Masahiro, Kawakubo Hirofumi, Booka Eisuke, Yamatsuji Tomoki, Kato Hiroyuki, Ito Yoshinori, Ishikawa Hitoshi, Ishihara Ryu, Tsushima Takahiro, Kawachi Hiroshi, Oyama Takashi, Kojima Takashi, Kuribayashi Shiko, Makino Tomoki, Matsuda Satoru, Sohda Makoto, Kubo Yuto, Doki Yuichiro

Esophagus : official journal of the Japan Esophageal Society 19 ( 1 ) 27 - 38 2022.1（ ISSN:1612-9059 ）

Comprehensive registry of esophageal cancer in Japan, 2014.

Watanabe Masayuki, Toh Yasushi, Ishihara Ryu, Kono Koji, Matsubara Hisahiro, Murakami Kentaro, Muro Kei, Numasaki Hodaka, Oyama Tsuneo, Ozawa Soji, Saeki Hiroshi, Tanaka Koji, Tsushima Takahiro, Ueno Masaki, Uno Takashi, Yoshio Toshiyuki, Usune Shiyori, Takahashi Arata, Miyata Hiroaki

Esophagus 19 ( 1 ) 1 - 26 2022.1（ ISSN:1612-9059 ）

Impact of histological subtype on prognosis in stage IV colorectal cancer: A population-based cohort study.

Miyakawa T, Kawamura H, Honda M, Takano Y, Kinuta S, Kamiga T, Yamazaki S, Muto A, Shiraso S, Yamashita N, Iwao T, Kono K, Konno S

PloS one 17 ( 3 ) e0264652 2022

High Risk Stage II大腸癌におけるGlasgow Prognostic Scoreの意義と治療戦略

大木進司, 岡山洋和, 千田峻, 坂本渉, 藤田正太郎, 齋藤元伸, 門馬智之, 佐瀬善一郎, 河野浩二

癌と化学療法 48 ( 13 ) 1770 - 1773 2021.12（ ISSN:0385-0684 ）

Functional benefits of the double flap technique after proximal gastrectomy for gastric cancer.

Saze Z, Kase K, Nakano H, Yamauchi N, Kaneta A, Watanabe Y, Hanayama H, Hayase S, Momma T, Kono K

BMC surgery 21 ( 1 ) 392 - 392 2021.11

Functional benefits of the double flap technique after proximal gastrectomy for gastric cancer.

Saze Z, Kase K, Nakano H, Yamauchi N, Kaneta A, Watanabe Y, Hanayama H, Hayase S, Momma T, Kono K

BMC surgery 21 ( 1 ) 392 - 392 2021.11

Functional benefits of the double flap technique after proximal gastrectomy for gastric cancer.

Saze Z, Kase K, Nakano H, Yamauchi N, Kaneta A, Watanabe Y, Hanayama H, Hayase S, Momma T, Kono K

BMC surgery 21 ( 1 ) 392 - 392 2021.11

A grading system for predicting the prognosis of gastric cancer with liver metastasis.

Hori S, Honda M, Kobayashi H, Kawamura H, Takiguchi K, Muto A, Yamazaki S, Teranishi Y, Shiraso S, Kono K, Kamiga T, Iwao T, Yamashita N

Japanese journal of clinical oncology 51 ( 11 ) 1601 - 1607 2021.11（ ISSN:0368-2811 ）

Clinical Impact of Primary Tumor Site in Stage IV Colorectal Cancer: A Statewide Cohort Study.

Kawamura H, Honda M, Takiguchi K, Kamiga T, Saito K, Muto A, Shiraso S, Yamashita N, Iwao T, Saji S, Kono K, Konno S

Anticancer research 41 ( 11 ) 5693 - 5702 2021.11（ ISSN:0250-7005 ）

Impact of Primary Tumor Resection on Mortality in Patients with Stage IV Colorectal Cancer with Unresectable Metastases: A Multicenter Retrospective Cohort Study.

Kawamura H, Ogawa Y, Yamazaki H, Honda M, Kono K, Konno S, Fukuhara S, Yamamoto Y

World journal of surgery 45 ( 10 ) 3230 - 3239 2021.10（ ISSN:0364-2313 ）

The Expression of Immune Checkpoint Receptors and Ligands in the Colorectal Cancer Tumor Microenvironment.

Neupane P, Mimura K, Nakajima S, Okayama H, Ito M, Thar Min AK, Saito K, Onozawa H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Kono K

Anticancer research 41 ( 10 ) 4895 - 4905 2021.10（ ISSN:0250-7005 ）

Immunotherapy Targeting Tumor-Associated Carbohydrate Antigens in Deficient Mismatch Repair Colorectal Cancer

Matsumoto T, Okayama H, Nakano H, Ito M, Nakajima S, Saito M, Saze Z, Momma T, Mimura K, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 10 ) 1275 - 1277 2021.10（ ISSN:03850684 ）

Immunotherapy Targeting Tumor-Associated Carbohydrate Antigens in Deficient Mismatch Repair Colorectal Cancer

Matsumoto T, Okayama H, Nakano H, Ito M, Nakajima S, Saito M, Saze Z, Momma T, Mimura K, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 10 ) 1275 - 1277 2021.10（ ISSN:0385-0684 ）

胃癌の免疫療法

河野浩二

医学と薬学 78 ( 10 ) 1183 - 1190 2021.10

ミスマッチ修復機構欠損大腸癌における糖鎖抗原を標的とした免疫療法の可能性

松本拓朗, 岡山洋和, 仲野宏, 伊藤美郷, 中嶋正太郎, 齋藤元伸, 佐瀬善一郎, 門馬智之, 三村耕作, 河野浩二

癌と化学療法 48 ( 10 ) 1275 - 1277 2021.10（ ISSN:0385-0684 ）

The Expression of Immune Checkpoint Receptors and Ligands in the Colorectal Cancer Tumor Microenvironment.

Neupane P, Mimura K, Nakajima S, Okayama H, Ito M, Thar Min AK, Saito K, Onozawa H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Kono K

Anticancer research 41 ( 10 ) 4895 - 4905 2021.10

Validation of Gene Expression-Based Predictive Biomarkers for Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.

Momma T, Okayama H, Kanke Y, Fukai S, Onozawa H, Fujita S, Sakamoto W, Saito M, Ohki S, Kono K

Cancers 13 ( 18 ) 4642 - 4642 2021.9

Validation of Gene Expression-Based Predictive Biomarkers for Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer.

Momma T, Okayama H, Kanke Y, Fukai S, Onozawa H, Fujita S, Sakamoto W, Saito M, Ohki S, Kono K

Cancers 13 ( 18 ) 4642 - 4642 2021.9

Landscape of EBV-positive gastric cancer.

Saito M, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 5 ) 983 - 989 2021.9（ ISSN:1436-3291 ）

Landscape of EBV-positive gastric cancer.

Saito Motonobu, Kono Koji

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 5 ) 983 - 989 2021.9（ ISSN:1436-3291 ）

The Association between Intestinal Bacteria and Tumor Infiltrating Immune Cells in the Tumor Microenvironment of Colorectal Cancer

Mimura K, Kikuchi T, Kono K

Japanese Journal of Cancer and Chemotherapy 48 ( 9 ) 1093 - 1095 2021.9（ ISSN:0385-0684 ）

正中弓状靱帯圧迫症候群に伴う胃十二指腸動脈瘤により出血性十二指腸潰瘍をきたした1例

仲野宏, 渡辺洋平, 伊藤美郷, 加瀬晃志, 山内直人, 松本拓朗, 金田晃尚, 花山寛之, 早瀬傑, 門馬智之, 佐瀬善一郎, 三村耕作, 河野浩二

日本腹部救急医学会雑誌 41 ( 6 ) 449 - 452 2021.9（ ISSN:1340-2242 ）

【腸内細菌とがん微小環境のかかわり】大腸癌腫瘍微小環境における腸内細菌と腫瘍浸潤免疫担当細胞の関連について

三村耕作, 菊池智宏, 河野浩二

癌と化学療法 48 ( 9 ) 1093 - 1095 2021.9（ ISSN:0385-0684 ）

Landscape of EBV-positive gastric cancer.

Saito M, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 5 ) 983 - 989 2021.9

The Association between Intestinal Bacteria and Tumor Infiltrating Immune Cells in the Tumor Microenvironment of Colorectal Cancer

Mimura K, Kikuchi T, Kono K

Japanese Journal of Cancer and Chemotherapy 48 ( 9 ) 1093 - 1095 2021.9（ ISSN:03850684 ）

The role of KRT17 in colorectal cancer.

Ujiie D, Okayama H, Kono K

Aging 13 ( 16 ) 19950 - 19951 2021.8

The role of KRT17 in colorectal cancer.

Ujiie D, Okayama H, Kono K

Aging 13 ( 16 ) 19950 - 19951 2021.8

The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells.

Nakajima S, Mimura K, Matsumoto T, Thar Min AK, Ito M, Nakano H, Neupane P, Kanke Y, Okayama H, Saito M, Momma T, Watanabe Y, Hanayama H, Hayase S, Saze Z, Kono K

Scientific reports 11 ( 1 ) 16891 - 16891 2021.8

術前確定診断された肺癌胃転移に対して腹腔鏡下切除術を施行した1例

望月翔太朗, 山田玲央, 加瀬晃志, 伊藤美郷, 仲野宏, 山内直人, 松本拓朗, 金田晃尚, 菅家康之, 中島隆宏, 花山寛之, 渡辺洋平, 小野澤寿志, 早瀬傑, 岡山洋和, 藤田正太郎, 坂本渉, 齋藤元伸, 門馬智之, 佐瀬善一郎, 三村耕作, 大木進司, 河野浩二

癌と化学療法 48 ( 8 ) 1057 - 1060 2021.8（ ISSN:0385-0684 ）

A Case of Laparoscopic Surgery for Preoperatively Diagnosed Gastric Metastasis of Lung Cancer

Mochizuki S, Yamada L, Kase K, Ito M, Nakano H, Yamauchi N, Matsumoto T, Kaneta A, Kanke Y, Nakajima T, Hanayama H, Watanabe Y, Onozawa H, Hayase S, Okayama H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Mimura K, Ohki S, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 48 ( 8 ) 1057 - 1060 2021.8（ ISSN:03850684 ）

A case of lipoma, calcification, and brain malformations in the midline of the skull.

Kanazawa H, Gonda K, Tamura T, Takenoshita S.

Radiol Case Rep. 16 ( 9 ) 2509 - 2513 2021.7

Circulating tumor cells after neoadjuvant chemotherapy are related with recurrence in esophageal squamous cell carcinoma.

Ujiie D, Matsumoto T, Endo E, Okayama H, Fujita S, Kanke Y, Watanabe Y, Hanayama H, Hayase S, Saze Z, Ohki S, Kono K

Esophagus : official journal of the Japan Esophageal Society 18 ( 3 ) 566 - 573 2021.7（ ISSN:1612-9059 ）

Benefit of intensive chemotherapy for elderly patients aged 80 years or older with metastatic colorectal cancer: a state-wide multicenter cohort study.

Nakayama Y, Kawamura H, Honda M, Takano Y, Takiguchi K, Kamiga T, Yamazaki S, Muto A, Shiraso S, Yamashita N, Iwao T, Kono K, Konno S

International journal of clinical oncology 26 ( 7 ) 1248 - 1256 2021.7（ ISSN:1341-9625 ）

Benefit of intensive chemotherapy for elderly patients aged 80 years or older with metastatic colorectal cancer: a state-wide multicenter cohort study.

Nakayama Yujiro, Kawamura Hidetaka, Honda Michitaka, Takano Yoshinao, Takiguchi Koichi, Kamiga Takahiro, Yamazaki Shigeru, Muto Atsushi, Shiraso Satoru, Yamashita Naoyuki, Iwao Toshiyasu, Kono Koji, Konno Shinichi

International journal of clinical oncology 26 ( 7 ) 1248 - 1256 2021.7（ ISSN:1341-9625 ）

Circulating tumor cells after neoadjuvant chemotherapy are related with recurrence in esophageal squamous cell carcinoma.

Ujiie D, Matsumoto T, Endo E, Okayama H, Fujita S, Kanke Y, Watanabe Y, Hanayama H, Hayase S, Saze Z, Ohki S, Kono K

Esophagus : official journal of the Japan Esophageal Society 18 ( 3 ) 566 - 573 2021.7

Benefit of intensive chemotherapy for elderly patients aged 80 years or older with metastatic colorectal cancer: a state-wide multicenter cohort study.

Nakayama Y, Kawamura H, Honda M, Takano Y, Takiguchi K, Kamiga T, Yamazaki S, Muto A, Shiraso S, Yamashita N, Iwao T, Kono K, Konno S

International journal of clinical oncology 26 ( 7 ) 1248 - 1256 2021.7

Chemoradiation induces upregulation of immunogenic cell death-related molecules together with increased expression of PD-L1 and galectin-9 in gastric cancer.

S H Petersen, L F Kua, S Nakajima, W P Yong, K Kono

Scientific reports 11 ( 1 ) 12264 - 12264 2021.6

Stromal expression of cancer-associated fibroblast-related molecules, versican and lumican, is strongly associated with worse relapse-free and overall survival times in patients with esophageal squamous cell carcinoma.

Yamauchi N, Kanke Y, Saito K, Okayama H, Yamada S, Nakajima S, Endo E, Kase K, Yamada L, Nakano H, Matsumoto T, Hanayama H, Watanabe Y, Hayase S, Saito M, Saze Z, Mimura K, Momma T, Oki S, Hashimoto Y, Kono K

Oncology letters 21 ( 6 ) 445 - 445 2021.6（ ISSN:1792-1074 ）

Neoadjuvant Chemotherapy Induces IL34 Signaling and Promotes Chemoresistance via Tumor-Associated Macrophage Polarization in Esophageal Squamous Cell Carcinoma.

Nakajima S, Mimura K, Saito K, Thar Min AK, Endo E, Yamada L, Kase K, Yamauchi N, Matsumoto T, Nakano H, Kanke Y, Okayama H, Saito M, Neupane P, Saze Z, Watanabe Y, Hanayama H, Hayase S, Kaneta A, Momma T, Ohki S, Ohira H, Kono K

Molecular cancer research : MCR 19 ( 6 ) 1085 - 1095 2021.6（ ISSN:1541-7786 ）

Neoadjuvant Chemotherapy Induces IL34 Signaling and Promotes Chemoresistance via Tumor-Associated Macrophage Polarization in Esophageal Squamous Cell Carcinoma.

Molecular cancer research : MCR 19 ( 6 ) 1085 - 1095 2021.6

Oncology letters 21 ( 6 ) 445 - 445 2021.6

Ingestion of Okinawa Island Vegetables Increases IgA Levels and Prevents the Spread of Influenza RNA Viruses.

Gonda K, Kanazawa H, Maeda G, Matayoshi C, Hirose N, Katsumoto Y, Kono K, Takenoshita S

Ingestion of Okinawa Island Vegetables Increases IgA Levels and Prevents the Spread of Influenza RNA Viruses. 13 ( 6 ) 1773 - 1773 2021.5

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.

Mimura K, Kua LF, Xiao JF, Asuncion BR, Nakayama Y, Syn N, Fazreen Z, Soong R, Kono K, Yong WP

Gastric Cancer 24 ( 3 ) 611 - 623 2021.5（ ISSN:1436-3291 ）

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.

Mimura K, Kua LF, Xiao JF, Asuncion BR, Nakayama Y, Syn N, Fazreen Z, Soong R, Kono K, Yong WP

Gastric Cancer 24 ( 3 ) 611 - 623 2021.5（ ISSN:1436-3291 ）

Combined inhibition of PD-1/PD-L1, Lag-3, and Tim-3 axes augments antitumor immunity in gastric cancer-T cell coculture models.

Mimura K, Kua LF, Xiao JF, Asuncion BR, Nakayama Y, Syn N, Fazreen Z, Soong R, Kono K, Yong WP

Gastric Cancer. 24 ( 3 ) 611 - 623 2021.5

Long-term Outcomes of Lower Rectal Cancer Patients Treated with Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection after Preoperative Radiotherapy or Chemoradiotherapy.

Sakamoto Wataru, Ohki Shinji, Onozawa Hisashi, Okayama Hirokazu, Endo Hisahito, Fujita Shotaro, Saito Motonobu, Saze Zenichiro, Momma Tomoyuki, Takenoshita Seiichi, Kono Koji

Journal of the anus, rectum and colon 5 ( 2 ) 129 - 136 2021.4

Long-term Outcomes of Lower Rectal Cancer Patients Treated with Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection after Preoperative Radiotherapy or Chemoradiotherapy.

Sakamoto W, Ohki S, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Takenoshita S, Kono K

Journal of the anus, rectum and colon 5 ( 2 ) 129 - 136 2021.4

Long-term Outcomes of Lower Rectal Cancer Patients Treated with Total Mesorectal Excision and Lateral Pelvic Lymph Node Dissection after Preoperative Radiotherapy or Chemoradiotherapy.

Sakamoto W, Ohki S, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Takenoshita S, Kono K

Journal of the anus, rectum and colon 5 ( 2 ) 129 - 136 2021.4

Gastric carcinoma with lymphoid stroma diagnosed by endoscopic ultrasound-guided fine-needle aspiration.

Yanagita T, Hikichi T, Nakamura J, Watanabe K, Kikuchi H, Takasumi M, Hashimoto M, Kato T, Kobashi R, Takagi T, Suzuki R, Sugimoto M, Sato Y, Irie H, Hanayama H, Saze Z, Kobayakawa M, Kono K, Ohira H

Clinical journal of gastroenterology 14 ( 2 ) 471 - 477 2021.4（ ISSN:1865-7257 ）

Gastric carcinoma with lymphoid stroma diagnosed by endoscopic ultrasound-guided fine-needle aspiration.

Yanagita Takumi, Hikichi Takuto, Nakamura Jun, Watanabe Ko, Kikuchi Hitomi, Takasumi Mika, Hashimoto Minami, Kato Tsunetaka, Kobashi Ryoichiro, Takagi Tadayuki, Suzuki Rei, Sugimoto Mitsuru, Sato Yuki, Irie Hiroki, Hanayama Hiroyuki, Saze Zenichiro, Kobayakawa Masao, Kono Koji, Ohira Hiromasa

Clinical journal of gastroenterology 14 ( 2 ) 471 - 477 2021.4（ ISSN:1865-7257 ）

Gastric carcinoma with lymphoid stroma diagnosed by endoscopic ultrasound-guided fine-needle aspiration.

Yanagita T, Hikichi T, Nakamura J, Watanabe K, Kikuchi H, Takasumi M, Hashimoto M, Kato T, Kobashi R, Takagi T, Suzuki R, Sugimoto M, Sato Y, Irie H, Hanayama H, Saze Z, Kobayakawa M, Kono K, Ohira H

Clinical journal of gastroenterology 14 ( 2 ) 471 - 477 2021.4

Collision of Epstein-Barr virus-positive and -negative gastric cancer, diagnosed by molecular analysis: a case report.

Miyabe K, Saito M, Koyama K, Umakoshi M, Ito Y, Yoshida M, Kudo-Asabe Y, Saito K, Nanjo H, Maeda D, Matsusaka K, Goto A, Kono K

BMC gastroenterology 21 ( 1 ) 97 - 97 2021.3

FOCUS　複合的免疫療法　放射線照射とがん免疫療法の併用療法

河野浩二

臨床外科 76 ( 3 ) 356 - 361 2021.3（ ISSN:0386-9857 ）

Downregulation of PAICS due to loss of chromosome 4q is associated with poor survival in stage III colorectal cancer.

Kobayashi Y, Kumamoto K, Okayama H, Matsumoto T, Nakano H, Saito K, Matsumoto Y, Endo E, Kanke Y, Watanabe Y, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Takenoshita S, Kono K

PloS one 16 ( 2 ) e0247169 2021.2

ARID1A deficiency in EBV-positive gastric cancer is partially regulated by EBV-encoded miRNAs, but not by DNA promotor hypermethylation.

Kase K, Saito M, Nakajima S, Takayanagi D, Saito K, Yamada L, Ashizawa M, Nakano H, Hanayama H, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Shiraishi K, Kohno T, Kono K

Carcinogenesis 42 ( 1 ) 21 - 30 2021.2（ ISSN:0143-3334 ）

The Nepalese health care system and challenges during COVID-19.

Neupane P, Bhandari D, Tsubokura M, Shimazu Y, Zhao T, Kono K

Journal of global health 11 03030 - 03030 2021.2（ ISSN:2047-2978 ）

Ficus pumila L. improves the prognosis of patients infected with HTLV-1, an RNA virus.

Gonda K, Suzuki K, Sunabe Y, Kono K, Takenoshita S

Nutrition journal 20 ( 1 ) 16 2021.2

Therapeutic potential of anti-VEGF receptor 2 therapy targeting for M2-tumor-associated macrophages in colorectal cancer.

Min AKT, Mimura K, Nakajima S, Okayama H, Saito K, Sakamoto W, Fujita S, Endo H, Saito M, Saze Z, Momma T, Ohki S, Kono K

Cancer immunology, immunotherapy : CII 70 ( 2 ) 289 - 298 2021.2（ ISSN:0340-7004 ）

Extensive peritoneal lavage with saline after curative gastrectomy for gastric cancer (EXPEL): a multicentre randomised controlled trial.

Yang HK, Ji J, Han SU, Terashima M, Li G, Kim HH, Law S, Shabbir A, Song KY, Hyung WJ, Kosai NR, Kono K, Misawa K, Yabusaki H, Kinoshita T, Lau PC, Kim YW, Rao JR, Ng E, Yamada T, Yoshida K, Park DJ, Tai BC, So JBY, EXPEL study group.

The lancet. Gastroenterology & hepatology 6 ( 2 ) 120 - 127 2021.2（ ISSN:24681253 ）

PD-L1 overexpression in EBV-positive gastric cancer is caused by unique genomic or epigenomic mechanisms.

Nakano H, Saito M, Nakajima S, Saito K, Nakayama Y, Kase K, Yamada L, Kanke Y, Hanayama H, Onozawa H, Okayama H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Goto A, Kono K

Scientific reports 11 ( 1 ) 1982 - 1982 2021.1

Registration Committee for Esophageal Cancer of the Japan Esophageal Society. Comprehensive registry of esophageal cancer in Japan, 2013.

Watanabe M, Tachimori Y, Oyama T, Toh Y, Matsubara H, Ueno M, Kono K, Uno T, Ishihara R, Muro K, Numasaki H, Tanaka K, Ozawa S, Murakami K, Usune S, Takahashi A, Miyata H.

Esophagus. 18 ( 1 ) 1 - 24 2021.1

Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer.

Yamada L, Saito M, Thar Min AK, Saito K, Ashizawa M, Kase K, Nakajima S, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 1 ) 60 - 71 2021.1（ ISSN:1436-3291 ）

新型コロナウイルス感染症(COVID-19)パンデミック時の食道癌手術で気をつけることは?　ICUの機能低下や、人工呼吸器不足、医療チームのマンパワーなどを慎重に判断して、食道癌の手術療法を実施する必要がある

河野浩二, 藤原俊義

日本医事新報 ( 5046 ) 50 - 51 2021.1（ ISSN:0385-9215 ）

外科系新専門医制度のあるべきグランドデザイン　GeneralityとSpecialtyのバランスのとれた外科医の育成を目指して　なんでもできる外科医の魅力をもう一度

木村隆, 横山斉, 鈴木眞一, 河野浩二, 丸橋繁, 鈴木弘行, 大竹徹, 田中秀明

日本外科学会雑誌 122 ( 1 ) 90 - 92 2021.1（ ISSN:0301-4894 ）

Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer.

Yamada L, Saito M, Thar Min AK, Saito K, Ashizawa M, Kase K, Nakajima S, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 1 ) 60 - 71 2021.1（ ISSN:1436-3291 ）

Comprehensive registry of esophageal cancer in Japan, 2013.

Watanabe M, Tachimori Y, Oyama T, Toh Y, Matsubara H, Ueno M, Kono K, Uno T, Ishihara R, Muro K, Numasaki H, Tanaka K, Ozawa S, Murakami K, Usune S, Takahashi A, Miyata H, Registration Committee for Esophageal Cancer of the Japan Esophageal Society.

Esophagus : official journal of the Japan Esophageal Society 18 ( 1 ) 1 - 24 2021.1（ ISSN:1612-9059 ）

2013年の食道癌全国登録(Comprehensive registry of esophageal cancer in Japan, 2013)

Watanabe Masayuki, Tachimori Yuji, Oyama Tsuneo, Toh Yasushi, Matsubara Hisahiro, Ueno Masaki, Kono Koji, Uno Takashi, Ishihara Ryu, Muro Kei, Numasaki Hodaka, Tanaka Koji, Ozawa Soji, Murakami Kentaro, Usune Shiyori, Takahashi Arata, Miyata Hiroaki, The Registration Committee for Esophageal Cancer of the Japan Esophageal Society

Esophagus 18 ( 1 ) 1 - 24 2021.1（ ISSN:1612-9059 ）

Selective sensitivity of EZH2 inhibitors based on synthetic lethality in ARID1A-deficient gastric cancer.

Yamada L, Saito M, Thar Min AK, Saito K, Ashizawa M, Kase K, Nakajima S, Onozawa H, Okayama H, Endo H, Fujita S, Sakamoto W, Saze Z, Momma T, Mimura K, Ohki S, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 24 ( 1 ) 61 - 71 2021.1

ハイブリッドアプローチで切除し得た骨盤内脂肪肉腫の1例

藤田正太郎, 門馬智之, 仲野宏, 山内直人, 山田玲央, 松本拓朗, 菅家康之, 花山寛之, 渡辺洋平, 小野澤寿志, 岡山洋和, 坂本渉, 齋藤元伸, 佐瀬善一郎, 河野浩二

癌と化学療法 47 ( 13 ) 1869 - 1871 2020.12

A Case of Pelvic Liposarcoma Resected by Hybrid Approach

Fujita S., Momma T., Nakano H., Yamauchi N., Yamada L., Matsumoto T., Kanke Y., Hanayama H., Watanabe Y., Onozawa H., Okayama H., Sakamoto W., Saito M., Saze Z., Kono K.

Gan to kagaku ryoho. Cancer & chemotherapy 47 ( 13 ) 1869 - 1871 2020.12（ ISSN:03850684 ）

Activation of the reward system ameliorates passive cutaneous anaphylactic reaction in mice.

Nakajima S, Manita S, Yu G, Ishimaru K, Kono K, Kitamura K, Nakao A

Allergy 75 ( 12 ) 3275 - 3279 2020.12（ ISSN:0105-4538 ）

Gastric adenocarcinoma with enteroblastic differentiation followed endoscopically: A case report.

Kimura T, Hikichi T, Nakamura J, Takasumi M, Hashimoto M, Kato T, Kobashi R, Takagi T, Suzuki R, Sugimoto M, Sato Y, Irie H, Saze Z, Kobayakawa M, Kono K, Ohira H

Clinical journal of gastroenterology 13 ( 6 ) 1074 - 1082 2020.12

内視鏡下に経過観察された胃胎児消化管上皮類似癌　1症例報告(Gastric adenocarcinoma with enteroblastic differentiation followed endoscopically: A case report)

Kimura Tomoya, Hikichi Takuto, Nakamura Jun, Takasumi Mika, Hashimoto Minami, Kato Tsunetaka, Kobashi Ryoichiro, Takagi Tadayuki, Suzuki Rei, Sugimoto Mitsuru, Sato Yuki, Irie Hiroki, Saze Zenichiro, Kobayakawa Masao, Kono Koji, Ohira Hiromasa

Clinical Journal of Gastroenterology 13 ( 6 ) 1074 - 1082 2020.12（ ISSN:1865-7257 ）

ハイブリッドアプローチで切除し得た骨盤内脂肪肉腫の1例

癌と化学療法 47 ( 13 ) 1869 - 1871 2020.12（ ISSN:0385-0684 ）

Gastric adenocarcinoma with enteroblastic differentiation followed endoscopically: A case report.

Kimura T, Hikichi T, Nakamura J, Takasumi M, Hashimoto M, Kato T, Kobashi R, Takagi T, Suzuki R, Sugimoto M, Sato Y, Irie H, Saze Z, Kobayakawa M, Kono K, Ohira H

Clinical journal of gastroenterology 13 ( 6 ) 1074 - 1082 2020.12（ ISSN:1865-7257 ）

[A Case of Pelvic Liposarcoma Resected by Hybrid Approach].

Fujita S, Momma T, Nakano H, Yamauchi N, Yamada L, Matsumoto T, Kanke Y, Hanayama H, Watanabe Y, Onozawa H, Okayama H, Sakamoto W, Saito M, Saze Z, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 47 ( 13 ) 1869 - 1871 2020.12（ ISSN:0385-0684 ）

Tn Antigen Expression Defines an Immune Cold Subset of Mismatch-Repair Deficient Colorectal Cancer.

Matsumoto T, Okayama H, Nakajima S, Saito K, Nakano H, Endo E, Kase K, Ito M, Yamauchi N, Yamada L, Kanke Y, Onozawa H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K

International journal of molecular sciences 21 ( 23 ) 9081 - 9081 2020.11

〔私たちの流儀〕第15回　世界を視野に入れ、外科臨床の実践を極めつつ、がん免疫療法の臨床を進める

河野浩二

D to D 41 14 - 17 2020.11

Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.

Nakayama Y, Mimura K, Kua LF, Okayama H, Min AKT, Saito K, Hanayama H, Watanabe Y, Saito M, Momma T, Saze Z, Ohki S, Suzuki Y, Ichikawa D, Yong WP, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 6 ) 961 - 973 2020.11（ ISSN:1436-3291 ）

IL-17A in Ovarian Cancer.

Watanabe T, Shibata M, Soeda S, Furukawa S, Fujimori K, Kono K, Takenoshita S.

Journal of Cancer Therapy. 11 ( 10 ) 605 - 616 2020.10

IL-17A in Ovarian Cancer.

Watanabe T, Shibata M, Soeda S, Furukawa S, Fujimori K, Kono K, Takenoshita S.

Journal of Cancer Therapy. 11 ( 10 ) 605 - 616 2020.10

【ガイドラインには書いていない-胃癌治療のCQ】免疫療法の展望　ニボルマブは今後も3次治療で,単剤で使用すべき薬剤なのか?

河野浩二

臨床外科 75 ( 10 ) 1190 - 1194 2020.10（ ISSN:0386-9857 ）

【基礎疾患、機能低下、認知症…術前管理も申し送りもスマートに!ハイリスク患者の術前術後ケア　サキヨミ★メソッド!】アレルギーのある患者さん

仲野宏, 河野浩二

消化器ナーシング 25 ( 10 ) 1002 - 1007 2020.10（ ISSN:2434-4575 ）

A TGFβ-dependent stromal subset underlies immune checkpoint inhibitor efficacy in DNA mismatch repair-deficient/microsatellite instability-high colorectal cancer.

Endo E, Okayama H, Saito K, Nakajima S, Yamada L, Ujiie D, Kase K, Fujita S, Endo H, Sakamoto W, Saito M, Saze Z, Momma T, Ohki S, Mimura K, Kono K.

Molecular cancer research : MCR 18 ( 9 ) 1402 - 1413 2020.9（ ISSN:1541-7786 ）

An ascites grading system for predicting the prognosis of gastric cancer with peritoneum dissemination.

Honda M, Kawamura H, Kobayashi H, Takiguchi K. Muto A, Yamazaki S, Teranishi Y, Shiraso S, Kono K, Hori S, KamigaT, Iwao T, Yamashita N.

Annals of Gastroenterological Surgery 4 ( 6 ) 660 - 666 2020.8

An ascites grading system for predicting the prognosis of gastric cancer with peritoneum dissemination.

Honda M, Kawamura H, Kobayashi H, Takiguchi K. Muto A, Yamazaki S, Teranishi Y, Shiraso S, Kono K, Hori S, KamigaT, Iwao T, Yamashita N.

Annals of Gastroenterological Surgery 4 ( 6 ) 660 - 666 2020.8

Diagnosis and treatment of gastric hamartomatous inverted polyp (GHIP) using a modified combination of laparoscopic and endoscopic approaches to neoplasia with a non-exposure technique (modified CLEAN-NET): a case report.

Hayase S, Sakuma M, Chida S, Saito M, Ami H, Koyama Y, Ohki S, Kono K

Surgical case reports 6 ( 1 ) 200 - 200 2020.8

Hayase S, Sakuma M, Chida S, Saito M, Ami H, Koyama Y, Ohki S, Kono K

Surgical case reports 6 ( 1 ) 200 - 200 2020.8

KRT17 as a prognostic biomarker for stage II colorectal cancer.

Ujiie D, Okayama H, Saito K, Ashizawa M, Thar Min AK, Endo E, Kase K, Yamada L, Kikuchi T, Hanayama H, Fujita S, Sakamoto W, Endo H, Saito M, Mimura K, Saze Z, Momma T, Ohki S, Kono K

Carcinogenesis 41 ( 5 ) 591 - 599 2020.7（ ISSN:0143-3334 ）

KRT17 as a prognostic biomarker for stage II colorectal cancer.

Ujiie D, Okayama H, Saito K, Ashizawa M, Thar Min AK, Endo E, Kase K, Yamada L, Kikuchi T, Hanayama H, Fujita S, Sakamoto W, Endo H, Saito M, Mimura K, Saze Z, Momma T, Ohki S, Kono K

Carcinogenesis 41 ( 5 ) 591 - 599 2020.7

Current status of immune checkpoint inhibitors for gastric cancer.

Kono K, Nakajima S, Mimura K.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 4 ) 565 - 578 2020.7（ ISSN:1436-3291 ）

Current status of immune checkpoint inhibitors for gastric cancer.

Kono K, Nakajima S, Mimura K.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 4 ) 565 - 578 2020.7

Heterogeneity of ARID1A expression in gastric cancer may affect patient survival and therapeutic efficacy.

Saito M, Kohno T, Kono K

Human pathology 101 80 - 81 2020.7

Current status of immune checkpoint inhibitors for gastric cancer.

Kono K, Nakajima S, Mimura K.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 23 ( 4 ) 565 - 578 2020.7（ ISSN:1436-3291 ）

Heterogeneity of ARID1A expression in gastric cancer may affect patient survival and therapeutic efficacy.

Saito M, Kohno T, Kono K

Human pathology 101 80 - 81 2020.5（ ISSN:0046-8177 ）

Immune suppression caused by PD-L2 expression on tumor cells in gastric cancer.

Nakayama Y, Mimura K, Kua LF, Okayama H, Min AKT, Saito K, Hanayama H, Watanabe Y, Saito M, Momma T, Saze Z, Ohki S, Suzuki Y, Ichikawa D, Yong WP, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020.5（ ISSN:1436-3291 ）

癌と炎症を学ぶ(第7回)　Barrett食道癌と炎症

松本拓朗, 河野浩二

消化器外科 43 ( 6 ) 1039 - 1043 2020.5（ ISSN:0387-2645 ）

【消化管症候群(第3版)-その他の消化管疾患を含めて-】空腸、回腸、盲腸、結腸、直腸(上)　先天性異常、遺伝性疾患　Turcot症候群

門馬智之, 加瀬晃志, 遠藤英成, 野水整, 河野浩二.

別冊日本臨床　領域別症候群シリーズ№11　消化管症候群（第3版）Ⅲ－その他の消化管疾患を含めて－ 11 345 - 348 2020.4（ ISSN:0047-1852 ）

Higher modified Glasgow Prognostic Score and multiple stapler firings for rectal transection are risk factors for anastomotic leakage after low anterior resection in rectal cancer.

Sakamoto W, Ohki S, Kikuchi T, Okayama H, Fujita S, Endo H, Saito M, Saze Z, Momma T, Kono K

Fukushima journal of medical science 66 ( 1 ) 10 - 16 2020.4（ ISSN:0016-2590 ）

Higher modified Glasgow Prognostic Score and multiple stapler firings for rectal transection are risk factors for anastomotic leakage after low anterior resection in rectal cancer.

Sakamoto W, Ohki S, Kikuchi T, Okayama H, Fujita S, Endo H, Saito M, Saze Z, Momma T, Kono K

Fukushima journal of medical science 66 ( 1 ) 10 - 16 2020.4（ ISSN:0016-2590 ）

Higher modified Glasgow Prognostic Score and multiple stapler firings for rectal transection are risk factors for anastomotic leakage after low anterior resection in rectal cancer.

Sakamoto W, Ohki S, Kikuchi T, Okayama H, Fujita S, Endo H, Saito M, Saze Z, Momma T, Kono K

Fukushima journal of medical science 66 ( 1 ) 10 - 16 2020.4

cutting-edge medicineがん診療の副作用マネジメント　複合がん免疫療法の発展を目指して

中嶋正太郎, 河野浩二

Precision Medicine 3 ( 4 ) 299 - 302 2020.4（ ISSN:2434-3625 ）

【消化器外科手術の論点2020　誌上ディベートと手術手技】食道外科　食道切除後の標準的再建ルート　後縦隔再建の立場から

大木進司, 河野浩二.

手術 74 ( 4 ) 432 - 438 2020.3（ ISSN:0037-4423 ）

Orthotopic Implantation Achieves Better Engraftment and Faster Growth Than Subcutaneous Implantation in Breast Cancer Patient-Derived Xenografts.

Okano M, Oshi M, Butash A, Okano I, Saito K, Kawaguchi T, Nagahashi M, Kono K, Ohtake T, Takabe K

Journal of mammary gland biology and neoplasia 25 ( 1 ) 27 - 36 2020.3（ ISSN:1083-3021 ）

Orthotopic Implantation Achieves Better Engraftment and Faster Growth Than Subcutaneous Implantation in Breast Cancer Patient-Derived Xenografts.

Okano M, Oshi M, Butash A, Okano I, Saito K, Kawaguchi T, Nagahashi M, Kono K, Ohtake T, Takabe K

Journal of mammary gland biology and neoplasia 25 ( 1 ) 27 - 36 2020.3

【消化管症候群(第3版)-その他の消化管疾患を含めて-】肛門　腫瘍　直腸肛門部悪性黒色腫

門馬智之, 佐久間芽衣, 佐藤孝洋, 小山善久, 河野浩二.

別冊日本臨床　領域別症候群シリーズ№10　消化管症候群（第3版）Ⅱ－その他の消化管疾患を含めて－ 10 332 - 335 2020.2（ ISSN:0047-1852 ）

Novel Breast Cancer Brain Metastasis Patient-Derived Orthotopic Xenograft Model for Preclinical Studies.

Oshi M, Okano M, Maiti A, Rashid OM, Saito K, Kono K, Matsuyama R, Endo I, Takabe K

Cancers 12 ( 2 ) 444 - 444 2020.2

Novel Breast Cancer Brain Metastasis Patient-Derived Orthotopic Xenograft Model for Preclinical Studies.

Oshi M, Okano M, Maiti A, Rashid OM, Saito K, Kono K, Matsuyama R, Endo I, Takabe K

Cancers 12 ( 2 ) 444 - 444 2020.2

Prevalence of Lynch syndrome among patients with upper urinary tract carcinoma in a Japanese hospital-based population.

Ito T, Kono K, Eguchi H, Okazaki Y, Yamamoto G, Tachikawa T, Akagi K, Okada Y, Kawakami S, Morozumi M, Tamaru J, Ishida H

Japanese journal of clinical oncology 50 ( 1 ) 80 - 88 2020.1（ ISSN:0368-2811 ）

Prevalence of Lynch syndrome among patients with upper urinary tract carcinoma in a Japanese hospital-based population(和訳中)

Ito Tetsuya, Kono Koji, Eguchi Hidetaka, Okazaki Yasushi, Yamamoto Gou, Tachikawa Tetsuhiko, Akagi Kiwamu, Okada Yohei, Kawakami Satoru, Morozumi Makoto, Tamaru Jun-ichi, Ishida Hideyuki

Japanese Journal of Clinical Oncology 50 ( 1 ) 80 - 88 2020.1（ ISSN:0368-2811 ）

Characterization of tumor-infiltrating immune cells in relation to microbiota in colorectal cancers.

Kikuchi T, Mimura K, Ashizawa M, Okayama H, Endo E, Saito K, Sakamoto W, Fujita S, Endo H, Saito M, Momma T, Saze Z, Ohki S, Shimada K, Yoshimura K, Tsunoda T, Kono K

Cancer immunology, immunotherapy : CII 69 ( 1 ) 23 - 32 2020.1（ ISSN:0340-7004 ）

Tuberculous peritonitis; The effectiveness of diagnostic laparoscopy and the perioperative infectious prevention: A case report.

Yamada L, Saito M, Aita T, Thar Min AK, Endo E, Kase K, Ujiie D, Hanayama H, Okayama H, Sakamoto W, Endo H, Fujita S, Saze Z, Momma T, Ohki S, Hamaguchi S, Kono K

International journal of surgery case reports 72 326 - 329 2020（ ISSN:22102612 ）

Tuberculous peritonitis; The effectiveness of diagnostic laparoscopy and the perioperative infectious prevention: A case report.

Yamada L, Saito M, Aita T, Thar Min AK, Endo E, Kase K, Ujiie D, Hanayama H, Okayama H, Sakamoto W, Endo H, Fujita S, Saze Z, Momma T, Ohki S, Hamaguchi S, Kono K

International journal of surgery case reports 72 326 - 329 2020

A TGFβ-dependent stromal subset underlies immune checkpoint inhibitor efficacy in DNA mismatch repair-deficient/microsatellite instability-high colorectal cancer.

Endo E, Okayama H, Saito K, Nakajima S, Yamada L, Ujiie D, Kase K, Fujita S, Endo H, Sakamoto W, Saito M, Saze Z, Momma T, Ohki S, Mimura K, Kono K.

Molecular cancer research : MCR 18 ( 9 ) 1402 - 1413 2020

第10 章腫瘍免疫学と移植免疫学がん細胞と正常非自己細胞に対する免疫応答

中尾篤人，井上修，氏家大輔，内田萌菜，柏木麻里子，香山尚子，河合利尚，木村元子，河野浩二，佐藤卓哉，竹田潔，中嶋正太郎，中野信浩，中山俊憲，中山勝文，廣瀬晃一，穂積勝人，村上正晃，村上悠二，八木良二，松嶋綱治，山田幸宏

基礎免疫学原著第6 版免疫系の機能とその異常 185 - 205 2020

消化器がん研究の最前線

河野浩二

GICancer Cutting Edge 2 ( 3 ) 2 - 3 2020

生涯教育セミナー記録 2019年度第27回日本外科学会生涯教育セミナー（東北地区）「各分野のガイドラインを紐解く」によせて

河野浩二

日本外科学会雑誌 121 ( 2 ) 249 - 249 2020

【消化管症候群(第3版)-その他の消化管疾患を含めて-】胃　腫瘍性疾患　Krukenberg腫瘍

佐瀬善一郎, 菅家康之, 山田玲央, 遠藤英成, 河野浩二.

別冊日本臨床　領域別症候群シリーズ№9　消化管症候群（第3版）Ⅰ－その他の消化管疾患を含めて－ 304 - 307 2019.12（ ISSN:0047-1852 ）

小網原発GISTの2例

松本拓朗, 大木進司, 門馬智之, 喜古雄一郎, 田﨑和洋, 河野浩二

日本臨床外科学会雑誌 80 ( 12 ) 2175 - 2182 2019.12

Cluster of differentiation 8 and programmed cell death ligand 1 expression in triple-negative breast cancer combined with autosomal dominant polycystic kidney disease and tuberous sclerosis complex: a case report.

Gonda K, Akama T, Nakamura T, Hashimoto E, Kyoya N, Rokkaku Y, Maejima Y, Horita S, Tachibana K, Abe N, Ohtake T, Shimomura K, Kono K, Saji S, Takenoshita S, Higashihara E

Journal of medical case reports 13 ( 1 ) 381 2019.12

Resveratrol inhibits IL-33-mediated mast cell activation by targeting the MK2/3-PI3K/Akt axis.

Nakajima S, Ishimaru K, Kobayashi A, Yu G, Nakamura Y, Oh-Oka K, Suzuki-Inoue K, Kono K, Nakao A

Scientific reports 9 ( 1 ) 18423 2019.12

A Case of Rectovaginal Fistula after Rectal Cancer Surgery Cured with Estriol Vaginal Tablet and Vaginal Lavage

Fujita S., Momma T., Endo E., Kase K., Ujiie D., Hanayama H., Watanabe Y., Okayama H., Sakamoto W., Endo H., Saito M., Saze Z., Ohki S., Kono K.

Gan to kagaku ryoho. Cancer & chemotherapy 46 ( 13 ) 2078 - 2080 2019.12（ ISSN:03850684 ）

直腸癌術後の直腸膣瘻に対し、エストリオール膣錠と膣洗浄にて治癒した1例

藤田正太郎, 門馬智之, 佐藤孝洋, 遠藤英成, 加瀬晃志, 氏家大輔, 菊池智宏, 楡井東, 花山寛之, 渡辺洋平, 岡山洋和, 坂本渉, 遠藤久仁, 齋藤元伸, 佐瀬善一郎, 大木進司, 河野浩二.

癌と化学療法 46 ( 13 ) 2078 - 2080 2019.12

直腸癌術後の直腸腟瘻に対しエストリオール腟錠と腟洗浄にて治癒した1例

藤田正太郎, 門馬智之, 遠藤英成, 加瀬晃志, 氏家大輔, 花山寛之, 渡辺洋平, 岡山洋和, 坂本渉, 遠藤久仁, 斎藤元伸, 佐瀬善一郎, 大木進司, 河野浩二

癌と化学療法 46 ( 13 ) 2078 - 2080 2019.12（ ISSN:0385-0684 ）

【消化管症候群(第3版)-その他の消化管疾患を含めて-】胃　腫瘍性疾患　EBウイルス関連胃癌

大木進司, 氏家大輔, 松本拓朗, 仲野宏, 河野浩二

別冊日本臨床領域別症候群シリーズ No.9 消化管症候群（第3版）Ⅰ －その他の消化管疾患を含めて－ 284 - 287 2019.12（ ISSN:0047-1852 ）

A subset of patients with MSS/MSI-low-colorectal cancer showed increased CD8(+) TILs together with up-regulated IFN-γ.

Kikuchi T, Mimura K, Okayama H, Nakayama Y, Saito K, Yamada L, Endo E, Sakamoto W, Fujita S, Endo H, Saito M, Momma T, Saze Z, Ohki S, Kono K

Oncology letters 18 ( 6 ) 5977 - 5985 2019.12（ ISSN:1792-1074 ）

[A Case of Rectovaginal Fistula after Rectal Cancer Surgery Cured with Estriol Vaginal Tablet and Vaginal Lavage].

Fujita S, Momma T, Endo E, Kase K, Ujiie D, Hanayama H, Watanabe Y, Okayama H, Sakamoto W, Endo H, Saito M, Saze Z, Ohki S, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 46 ( 13 ) 2078 - 2080 2019.12（ ISSN:0385-0684 ）

胃びまん性大細胞型B細胞性リンパ腫に併存した胃GISTの1例

松本拓朗, 圓谷秀哲, 伊藤泰輔, 石井芳正, 小田島肇, 河野浩二

日本臨床外科学会雑誌 80 ( 11 ) 2006 - 2012 2019.11

外科医となる自信を涵養する外科臨床実習　時代にマッチした外科医のリクルート

木村隆, 横山斉, 鈴木眞一, 河野浩二, 丸橋繁, 鈴木弘行, 大竹徹, 田中秀明

日本外科学会雑誌 120 ( 6 ) 713 - 715 2019.11

Microanatomy of inferior mesenteric artery sheath in colorectal cancer surgery.

Sakamoto W, Yamada L, Suzuki O, Kikuchi T, Okayama H, Endo H, Fujita S, Saito M, Momma T, Saze Z, Ohki S, Kono K

Journal of the anus, rectum and colon 3 ( 4 ) 167 - 174 2019.10

癌免疫カンファレンスルーム(最終回)　連載を終えるにあたって

河野浩二, 柴田昌彦

消化器外科 42 ( 11 ) 1610 - 1611 2019.10（ ISSN:0387-2645 ）

BZD9L1 sirtuin inhibitor as a potential adjuvant for sensitization of colorectal cancer cells to 5-fluorouracil.

Tan YJ, Lee YT, Petersen SH, Kaur G, Kono K, Tan SC, Majid AMSA, Oon CE.

Ther Adv Med Oncol 11 1 - 25 2019.9

Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis.

Okano M, Oshi M, Butash AL, Katsuta E, Tachibana K, Saito K, Okayama H, Peng X, Yan L, Kono K, Ohtake T, Takabe K

International journal of molecular sciences 20 ( 17 ) 2019.8（ ISSN:16616596 ）

Triple-Negative Breast Cancer with High Levels of Annexin A1 Expression Is Associated with Mast Cell Infiltration, Inflammation, and Angiogenesis.

Okano M, Oshi M, Butash AL, Katsuta E, Tachibana K, Saito K, Okayama H, Peng X, Yan L, Kono K, Ohtake T, Takabe K

International journal of molecular sciences 20 ( 17 ) 4197 - 4197 2019.8

【医療機器・介護機器開発を正しくおこなうための関連法とガイドラインの理解】高難度新規医療技術の導入プロセスが制度化された背景について

河野浩二, 南川一夫, 冨樫順一, 長谷川潔, 國土典宏

医療機器学 89 ( 4 ) 383 - 387 2019.8（ ISSN:1882-4978 ）

IL-17A in oncology.

Shibata M, Mimura K, Shimura T, Kono K, Ohto H, Takenoshita S.

Annals of Cancer Research and Therapy 27 ( 2 ) 59 - 63 2019.7（ ISSN:13446835 ）

IL-17A in oncology.

Shibata M, Mimura K, Shimura T, Kono K, Ohto H, Takenoshita S.

Annals of Cancer Research and Therapy 27 ( 2 ) 59 - 63 2019.7（ ISSN:1344-6835 ）

Explore the correlation between ARID1A and ANXA1 expressions in gastric cancer(和訳中)

Yamada Leo, Saito Motonobu, Min Aung Kyi Thar, Saito Katsuharu, Kase Koji, Onozawa Hisashi, Okayama Hirokazu, Fujita Shotaro, Endo Hisahito, Sakamoto Wataru, Saze Zenichiro, Momma Tomoyuki, Ohki Shinji, Mimura Kosaku, Kono Koji

Annals of Cancer Research and Therapy 27 ( 2 ) 46 - 51 2019.7（ ISSN:1344-6835 ）

Phospho‑STAT1 expression as a potential biomarker for anti‑PD‑1/anti‑PD‑L1 immunotherapy for breast cancer.

Nakayama Y, Mimura K, Tamaki T, Shiraishi K, Kua LF, Koh V, Ohmori M, Kimura A, Inoue S, Okayama H, Suzuki Y, Nakazawa T, Ichikawa D, Kono K

International journal of oncology 54 ( 6 ) 2030 - 2038 2019.6（ ISSN:1019-6439 ）

Noninvasive continuous blood pressure monitoring using microelectromechanical system technology.

Satake S, Shimura T, Ono T, Shimomura K, Takenoshita S, Kono K

Blood pressure monitoring 24 ( 3 ) 155 - 159 2019.6（ ISSN:1359-5237 ）

miRNA-148a-3p Regulates Immunosuppression in DNA Mismatch Repair-Deficient Colorectal Cancer by Targeting PD-L1.

Ashizawa M, Okayama H, Ishigame T, Thar Min AK, Saito K, Ujiie D, Murakami Y, Kikuchi T, Nakayama Y, Noda M, Tada T, Endo H, Fujita S, Sakamoto W, Saito M, Saze Z, Momma T, Ohki S, Mimura K, Kono K

Molecular cancer research : MCR 17 ( 6 ) 1403 - 1413 2019.6（ ISSN:1541-7786 ）

MLH1 germline mutation associated with Lynch syndrome in a family followed for more than 45 years.

Momma T, Gonda K, Akama Y, Endo E, Ujiie D, Fujita S, Maejima Y, Horita S, Shimomura K, Saji S, Kono K, Yashima R, Watanabe F, Sugano K, Nomizu T

BMC medical genetics 20 ( 1 ) 67 2019.5

Prognostic role of ARID1A negative expression in gastric cancer.

Ashizawa M, Saito M, Min AKT, Ujiie D, Saito K, Sato T, Kikuchi T, Okayama H, Fujita S, Endo H, Sakamoto W, Momma T, Ohki S, Goto A, Kono K

Scientific reports 9 ( 1 ) 6769 2019.5

The mechanism of PD-L1 expression and the development of biomarker of anti-PD-1/anti-PD-L1 monoclonal antibody from the viewpoint of IFN-γ

Nakayama Y., Mimura K., Kono K.

Japanese Journal of Cancer and Chemotherapy 46 ( 5 ) 838 - 840 2019.5（ ISSN:03850684 ）

食道癌リンパ節転移診断の進歩

佐瀬善一郎, 河野浩二.

日本外科学会雑誌 120 ( 3 ) 343 - 344 2019.5（ ISSN:0301-4894 ）

IFN一γの観点からみたPD－L1発現機構と抗PD－1／抗PD－L1抗体のバイオマーカー開発

中山裕子, 三村耕作, 河野浩二

癌と化学療法 46 ( 5 ) 838 - 840 2019.5

Molecular Genetics of Thymic Carcinoma.

Saito M, Kono K, Kohno T.

eLS 2019.5

IFN-γの観点からみたPD-L1発現機構と抗PD-1/抗PD-L1抗体のバイオマーカー開発

中山裕子, 三村耕作, 河野浩二.

癌と化学療法 46 ( 5 ) 838 - 840 2019.5

【がんにおけるPD-L1分子の発現調節】IFN-γの観点からみたPD-L1発現機構と抗PD-1/抗PD-L1抗体のバイオマーカー開発

中山裕子, 三村耕作, 河野浩二

癌と化学療法 46 ( 5 ) 838 - 840 2019.5（ ISSN:0385-0684 ）

[The Mechanism of PD-L1 Expression and the Development of Biomarker of Anti-PD-1/Anti-PD-L1 Monoclonal Antibody from the Viewpoint of IFN-γ].

Nakayama Y, Mimura K, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 46 ( 5 ) 838 - 840 2019.5（ ISSN:0385-0684 ）

Regulation on introducing process of the highly difficult new medical technologies: A survey on the current status of practice guidelines in Japan and overseas.

Minamikawa K, Okumura A, Kokudo N, Kono K

Bioscience trends 12 ( 6 ) 560 - 568 2019.1（ ISSN:1881-7815 ）

Anisakiasis in the Small Intestine with Excessive Bleeding That Was Difficult to Diagnose Endoscopically.

Kawashima K, Fujiwara T, Katakura K, Gunji N, Yokokawa A, Sakamoto A, Hikichi T, Kono K, Ohira H

Internal medicine 58 ( 1 ) 63 - 66 2019.1

Anisakiasis in the Small Intestine with Excessive Bleeding That Was Difficult to Diagnose Endoscopically.

Kawashima K, Fujiwara T, Katakura K, Gunji N, Yokokawa A, Sakamoto A, Hikichi T, Kono K, Ohira H

Internal medicine 58 ( 1 ) 63 - 66 2019.1（ ISSN:0918-2918 ）

Explore the correlation between ARID1A and ANXA1 expressions in gastric cancer.

Yamada L, Saito M, Min A, Saito K, Kase K, Onozawa H, Okayama H, Fujita S, Endo H, Sakamoto W, Saze Z, Momma T, Ohki S, Mimura K, Kono K

Annals of Cancer Research and Therapy 27 ( 2 ) 46 - 51 2019.1（ ISSN:13446835 ）

大量出血を生じ内視鏡検査では診断が困難であった小腸内のアニサキス症(Anisakiasis in the Small Intestine with Excessive Bleeding That Was Difficult to Diagnose Endoscopically)

Kawashima Kazumasa, Fujiwara Tatsuo, Katakura Kyoko, Gunji Naohiko, Yokokawa Aki, Sakamoto Ayumu, Hikichi Takuto, Kono Koji, Ohira Hiromasa

Internal Medicine 58 ( 1 ) 63 - 66 2019.1（ ISSN:0918-2918 ）

Expression profile of CADM1 and CADM4 in triple negative breast cancer with primary systemic therapy.

Kanke Y, Saito M, Abe N, Saito K, Goto A, Ohtake T, Murakami Y, Kono K

Oncology letters 17 ( 1 ) 921 - 926 2019.1（ ISSN:1792-1074 ）

高難度新規医療技術の導入プロセスが制度化された背景について

河野浩二, 南川一夫, 冨樫順一, 長谷川潔, 國土典宏

医療機器学 89 ( 4 ) 383 - 387 2019（ ISSN:1882-4978 ）

Clinical usefulness of ramucirumab plus paclitaxel for unresectable and recurrent gastric cancer.

Hayase S, Yamada L, Ujiie D, Nirei A, Tada T, Hanayama H, Monma T, Saze Z, Ohki S, Kono K

Fukushima journal of medical science 65 ( 1 ) 6 - 12 2019（ ISSN:0016-2590 ）

Microanatomy of inferior mesenteric artery sheath in colorectal cancer surgery.

Sakamoto W, Yamada L, Suzuki O, Kikuchi T, Okayama H, Endo H, Fujita S, Saito M, Momma T, Saze Z, Ohki S, Kono K

Journal of the anus, rectum and colon 3 ( 4 ) 167 - 174 2019

Clinical usefulness of ramucirumab plus paclitaxel for unresectable and recurrent gastric cancer.

Hayase S, Yamada L, Ujiie D, Nirei A, Tada T, Hanayama H, Monma T, Saze Z, Ohki S, Kono K

Fukushima journal of medical science 65 ( 1 ) 6 - 12 2019（ ISSN:0016-2590 ）

A Case of Esophageal Cancer with Cervical Lymph Node Recurrence Six Years after Complete Response to Definitive Chemoradiotherapy

Fujita S., Ohki S., Hayase S., Ujiie D., Kikuchi T., Tada T., Hanayama H., Okayama H., Sakamoto W., Endo H., Saito M., Gonda K., Saze Z., Momma T., Kono K.

Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1821 - 1823 2018.12（ ISSN:03850684 ）

Laparoscopic Endoscopic Cooperative Surgery(LECS)for Duodenal Tumors

Ohki S, Hikichi T, Momma T, Watanabe K, Nakamura J, Yamada R, Ujiie D, Nirei A, Tada T, Hanayama H, Watanabe Y, Hayase S, Gonda K, Saze Z, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 2024 - 2026 2018.12（ ISSN:03850684 ）

A Case Receiving Gastric Tube Resection for the Recurrence after a Proton Beam Irradiation in a Patient with Gastric Tube Cancer after Esophagectomy

Ujiie D, Kase K, Hayase S, Sakamoto W, Fujita S, Momma T, Saze Z, Ohki S, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1946 - 1948 2018.12（ ISSN:03850684 ）

A Case of Simultaneous Recurrence of Colon Cancer at the Drain Placement and Anastomotic Sites Postoperatively

Chida S., Kase K., Yashima R., Katagata N., Watanabe F., Nomizu T., Kono K.

Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1883 - 1885 2018.12（ ISSN:03850684 ）

A Case of Recurrent Colon Cancer with Long-Term Complete Response Treated with FOLFOX Therapy

Aoto K, Matsumoto S, Inoue N, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 2258 - 2260 2018.12（ ISSN:03850684 ）

HALSで修復した絞扼を伴う成人Bochdalek孔ヘルニア小腸嵌頓の1例

氏家大輔, 小野澤寿志, 遠藤英成, 千田峻, 渡辺洋平, 岡山洋和, 齋藤勝, 門馬智之, 佐瀬善一郎, 大木進司, 金澤匡司, 河野浩二

福島医学雑誌 68 ( 3 ) 173 - 176 2018.12（ ISSN:0016-2582 ）

根治的化学放射線療法で完全寛解した6年後に頸部リンパ節再発した食道癌の1例

藤田正太郎, 大木進司, 早瀬傑, 氏家大輔, 菊池智弘, 多田武志, 花山寛之, 岡山洋和, 坂本渉, 遠藤久仁, 斎藤元伸, 権田憲士, 佐瀬善一郎, 門馬智之, 河野浩二

癌と化学療法 45 ( 13 ) 1821 - 1823 2018.12（ ISSN:0385-0684 ）

十二指腸腫瘍に対する腹腔鏡内視鏡合同手術(LECS)の応用

大木進司, 引地拓人, 門馬智之, 渡辺晃, 中村純, 山田玲央, 氏家大輔, 楡井東, 多田武志, 花山寛之, 渡辺洋平, 早瀬傑, 権田憲二, 佐瀬善一郎, 河野浩二

癌と化学療法 45 ( 13 ) 2024 - 2026 2018.12（ ISSN:0385-0684 ）

胃管癌に対する陽子線照射後の再発例に対し胃管切除を実施した1例

氏家大輔, 加瀬晃志, 早瀬傑, 坂本渉, 藤田正太郎, 門馬智之, 佐瀬善一郎, 大木進司, 河野浩二

癌と化学療法 45 ( 13 ) 1946 - 1948 2018.12（ ISSN:0385-0684 ）

結腸癌術後にドレーン部と吻合部に同時再発した1例

千田峻, 加瀬晃志, 八島玲, 片方直人, 渡辺文明, 野水整, 河野浩二

癌と化学療法 45 ( 13 ) 1883 - 1885 2018.12（ ISSN:0385-0684 ）

高難度新規医療技術の導入プロセスに対する規制　日本と海外の診療ガイドラインの現状に関する調査(Regulation on introducing process of the highly difficult new medical technologies: A survey on the current status of practice guidelines in Japan and overseas)

Minamikawa Kazuo, Okumura Akiko, Kokudo Norihiro, Kono Koji

BioScience Trends 12 ( 6 ) 560 - 568 2018.12（ ISSN:1881-7815 ）

食道胃接合部腺癌術後の縦隔リンパ節再発に対して胸腔鏡下食道亜全摘術を施行した1例

花山寛之, 佐瀬善一郎, 山田玲央, 多田武志, 早瀬傑, 河野浩二

手術 72 ( 13 ) 1909 - 1913 2018.12（ ISSN:0037-4423 ）

転移性大腸癌患者用の予後モノグラムの開発　多施設共同後ろ向き観察コホート研究のプロトコル(Development of a prognostic nomogram for metastatic colorectal cancer patients: The study protocol of a multicenter, retrospective, observational, cohort study)

Kawamura Hidetaka, Honda Michitaka, Takiguchi Koichi, Kamiga Takahiro, Saito Katsumasa, Yamazaki Shigeru, Muto Atsushi, Shiraso Satoru, Yamashita Naoyuki, Iwao Toshiyasu, Saji Shigehira, Kono Koji

Annals of Cancer Research and Therapy 26 ( 2 ) 116 - 119 2018.12（ ISSN:1344-6835 ）

[A Case of Simultaneous Recurrence of Colon Cancer at the Drain Placement and Anastomotic Sites Postoperatively].

Chida S, Kase K, Yashima R, Katagata N, Watanabe F, Nomizu T, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 45 ( 13 ) 1883 - 1885 2018.12（ ISSN:0385-0684 ）

FOLFOXで長期Complete Responseを得た再発大腸癌の1例

青砥慶太, 松本進, 井上典夫, 河野浩二

癌と化学療法 45 ( 13 ) 2258 - 2260 2018.12（ ISSN:0385-0684 ）

Aberrant glycosylation in colorectal cancer with genomic and epigenomic alterations.

Okayama H, Noda M, Kono K

Oncotarget 9 ( 86 ) 35609 - 35610 2018.11

Prognostic impact of soluble intercellular adhesion molecule-1 in hepatocellular carcinoma.

Shimura T, Shibata M, Gonda K, Kofunato Y, Ishigame T, Okada R, Sato N, Kimura T, Kenjo A, Marubashi S.

Oncol Lett 16 ( 5 ) 6013 - 6018 2018.11

Prognostic impact of elevated preoperative C-reactive protein on patients with differentiated thyroid carcinoma.

Shimura T, Shibata M, Gonda K, Matsumoto Y, Nakano K, Iwadate M, Suzuki S, Suzuki S

J Surg Res 231 338 - 345 2018.11

Poland syndrome accompanied by internal iliac artery supply disruption sequence: a case report.

Gonda K, Tachiya Y, Hatakeyama Y, Momma T, Tamaoki T, Maejima Y, Rokkaku Y, Saji S, Shimomura K, Kono K

Journal of medical case reports 12 ( 1 ) 312 2018.10

A case of recurrent colon cancer with peritoneal dissemination treated with aflibercept showing partial response for one year

Gonda K, Fujita S, Shibata M, Hatakeyama Y, Tachiya Y, Rokkaku Y, Saze Z, Momma T, Ohki S, Saji S, Kono K

Japanese Journal of Cancer and Chemotherapy 45 ( 10 ) 1539 - 1542 2018.10（ ISSN:03850684 ）

A case of rectal colon cancer with paraneoplastic cerebellar degeneration

Gonda K, Kikuchi T, Shibata M, Hatakeyama Y, Tachiya Y, Rokkaku Y, Endo H, Fujita S, Sakamoto W, Hayase S, Okayama H, Hanayama H, Tada T, Nirei A, Ujiie D, Yamada R, Saze Z, Momma T, Ohki S, Kono K

Japanese Journal of Cancer and Chemotherapy 45 ( 10 ) 1510 - 1512 2018.10（ ISSN:03850684 ）

大腸癌再発症例にAfliberceptを投与しPRを得た症例

権田憲士, 藤田正太郎, 柴田昌彦, 畠山優一, 立谷陽介, 六角裕一, 佐瀬善一郎, 門馬智之, 大木進司, 佐治重衡, 河野浩二

癌と化学療法 45 ( 10 ) 1539 - 1542 2018.10（ ISSN:0385-0684 ）

傍腫瘍性小脳変性症に直腸癌を合併した1例

権田憲士, 菊池智弘, 柴田昌彦, 畠山優一, 立谷陽介, 六角裕一, 遠藤久仁, 藤田正太郎, 坂本渉, 早瀬傑, 岡山洋和, 花山寛之, 多田武志, 楡井東, 氏家大輔, 山田玲央, 佐瀬善一郎, 門馬智之, 大木進司, 河野浩二

癌と化学療法 45 ( 10 ) 1510 - 1512 2018.10（ ISSN:0385-0684 ）

免疫チェックポイント阻害剤ががん治療を変える

河野浩二

日本外科系連合学会誌 43 ( 5 ) 976 - 978 2018.10（ ISSN:0385-7883 ）

【食道癌(第2版)-基礎・臨床研究の進歩-】免疫チェックポイント阻害薬

中山裕子, 三村耕作, 河野浩二

日本臨床 76 ( 増刊8 ) 474 - 480 2018.10（ ISSN:0047-1852 ）

Identification of a novel therapeutic target in driver-negative non-small cell lung cancer.

Saito M, Kono K, Kohno T

Translational lung cancer research 7 ( Suppl 3 ) S218 - S220 2018.9（ ISSN:2218-6751 ）

Prognostic impact of preoperative lymphocyte-to-monocyte ratio in patients with colorectal cancer with special reference to myeloid-derived suppressor cells.

Shimura T, Shibata M, Gonda K, Hayase S, Sakamoto W, Okayama H, Fujita S, Saito M, Momma T, Ohki S, Kono K

Fukushima journal of medical science 64 ( 2 ) 64 - 72 2018.8（ ISSN:0016-2590 ）

Development of a prognostic nomogram for metastatic colorectal cancer patients: The study protocol of a multicenter, retrospective, observational, cohort study

Kawamura H, Honda M, Takiguchi K, Kamiga T, Saito K, Yamazaki S, Muto A, Shiraso S, Yamashita N, Iwao T, Saji S, Kono K

Annals of Cancer Research and Therapy 26 ( 2 ) 116 - 119 2018.8（ ISSN:13446835 ）

Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer.

Tan YJ, Lee YT, Yeong KY, Petersen SH, Kono K, Tan SC, Oon CE

Future medicinal chemistry 2018.8（ ISSN:1756-8919 ）

Immunotherapy for esophageal squamous cell carcinoma: a review.

Mimura K, Yamada L, Ujiie D, Hayase S, Tada T, Hanayama H, Thar Min AK, Shibata M, Momma T, Saze Z, Ohki S, Kono K

Fukushima journal of medical science 64 ( 2 ) 46 - 53 2018.8（ ISSN:0016-2590 ）

Immunotherapy for esophageal squamous cell carcinoma: a review

Mimura Kosaku, Saze Zenichiro, Ohki Shinji, Kono Koji, Yamada Leo, Ujiie Daisuke, Hayase Suguru, Tada Takeshi, Hanayama Hiroyuki, Thar Min Aung Kyi, Shibata Masahiko, Momma Tomoyuki

Fukushima J. Med. Sci. 2018.7（ ISSN:0016-2590 ）

Serum transthyretin level is associated with prognosis of patients with gastric cancer.

Shimura T, Shibata M, Gonda K, Okayama H, Saito M, Momma T, Ohki S, Kono K

Journal of Surgical Research 227 145 - 150 2018.7（ ISSN:00224804 ）

Advances in cancer immunotherapy for gastroenterological malignancy.

Kono K

Annals of gastroenterological surgery 2 ( 4 ) 244 - 245 2018.7

消化器外科手術アトラス　腹臥位鏡視下食道切除術　手術の定型化

河野浩二, 大木進司, 佐瀬善一郎, 仲野宏, 山田玲央, 氏家大輔, 楡井東, 花山寛之, 早瀬傑, 多田武志, 権田憲士, 門馬智之

消化器外科 41 ( 8 ) 1113 - 1123 2018.7（ ISSN:0387-2645 ）

Development of targeted therapy and immunotherapy for treatment of small cell lung cancer.

Saito M, Shiraishi K, Goto A, Suzuki H, Kohno T, Kono K

Japanese journal of clinical oncology 48 ( 7 ) 603 - 608 2018.7（ ISSN:0368-2811 ）

Epithelial-mesenchymal transition-converted tumor cells can induce T-cell apoptosis through upregulation of programmed death ligand 1 expression in esophageal squamous cell carcinoma.

Thar Min AK, Okayama H, Saito M, Ashizawa M, Aoto K, Nakajima T, Saito K, Hayase S, Sakamoto W, Tada T, Hanayama H, Saze Z, Momma T, Ohki S, Sato Y, Motoyama S, Mimura K, Kono K

Cancer medicine 2018.5

Epithelial-mesenchymal transition-converted tumor cells can induce T-cell apoptosis through upregulation of programmed death ligand 1 expression in esophageal squamous cell carcinoma.

Thar Min AK, Okayama H, Saito M, Ashizawa M, Aoto K, Nakajima T, Saito K, Hayase S, Sakamoto W, Tada T, Hanayama H, Saze Z, Momma T, Ohki S, Sato Y, Motoyama S, Mimura K, Kono K

Cancer medicine 7 ( 7 ) 3321 - 3330 2018.5

Glycosyltransferase gene expression identifies a poor prognostic colorectal cancer subtype associated with mismatch repair deficiency and incomplete glycan synthesis.

Noda M, Okayama H, Tachibana K, Sakamoto W, Saito K, Thar Min AK, Ashizawa M, Nakajima T, Aoto K, Momma T, Katakura K, Ohki S, Kono K

Clinical cancer research : an official journal of the American Association for Cancer Research 24 ( 18 ) 4468 - 4481 2018.5（ ISSN:1078-0432 ）

Development of targeted therapy and immunotherapy for treatment of small cell lung cancer.

Saito M, Shiraishi K, Goto A, Suzuki H, Kohno T, Kono K

Japanese journal of clinical oncology 2018.5（ ISSN:0368-2811 ）

Implication of Highly Cytotoxic Natural Killer Cells for Esophageal Squamous Cell Carcinoma Treatment.

Lim KS, Mimura K, Kua LF, Shiraishi K, Kono K

Journal of immunotherapy (Hagerstown, Md. : 1997) 41 ( 6 ) 261 - 273 2018.4（ ISSN:1524-9557 ）

Targeted therapy according to next generation sequencing-based panel sequencing.

Saito M, Momma T, Kono K

Fukushima journal of medical science 64 ( 1 ) 9 - 14 2018.4（ ISSN:0016-2590 ）

A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer.

Sundar R, Rha SY, Yamaue H, Katsuda M, Kono K, Kim HS, Kim C, Mimura K, Kua LF, Yong WP

BMC cancer 18 ( 1 ) 332 2018.3

A phase I/Ib study of OTSGC-A24 combined peptide vaccine in advanced gastric cancer

Sundar R., Rha S., Yamaue H., Katsuda M., Kono K., Kim H., Kim C., Mimura K., Kua L., Yong W.

BMC Cancer 18 ( 1 ) 2018.3

Angiogenesis: Managing the Culprits behind Tumorigenesis and Metastasis.

Yehya AHS, Asif M, Petersen SH, Subramaniam AV, Kono K, Majid AMSA, Oon CE

Medicina 54 ( 1 ) 8 2018.3（ ISSN:1010-660X ）

Clinical significance of serum transthyretin level in patients with hepatocellular carcinoma.

Shimura T, Shibata M, Kofunato Y, Okada R, Ishigame T, Kimura T, Kenjo A, Marubashi S

ANZ journal of surgery 2018.3（ ISSN:1445-1433 ）

Upregulated HOXA9 expression is associated with lymph node metastasis in colorectal cancer.

Watanabe Y, Saito M, Saito K, Matsumoto Y, Kanke Y, Onozawa H, Hayase S, Sakamoto W, Ishigame T, Momma T, Ohki S, Takenoshita S

Oncology letters 15 ( 3 ) 2756 - 2762 2018.3（ ISSN:1792-1074 ）

化学放射線療法が著効をみたAFP産生直腸癌局所再発の1例

伊藤泰輔, 石井芳正, 松本拓朗, 阿部貞彦, 河野浩二

日本臨床外科学会雑誌 79 ( 3 ) 537 - 541 2018.3（ ISSN:1345-2843 ）

NET G1と腺癌が共存した直腸原発MANECの1例

中島隆宏, 遠藤英成, 金澤匡司, 河野浩二

福島県農村医学会雑誌 58 ( 1 ) 8 - 11 2018.3（ ISSN:0911-9426 ）

Identification of candidate responders for anti-PD-L1/PD-1 immunotherapy, Rova-T therapy, or EZH2 inhibitory therapy in small-cell lung cancer.

Saito M, Saito K, Shiraishi K, Maeda D, Suzuki H, Minamiya Y, Kono K, Kohno T, Goto A

Molecular and clinical oncology 8 ( 2 ) 310 - 314 2018.2（ ISSN:2049-9450 ）

【腫瘍制御にかかわる各種細胞群】骨髄由来免疫抑制細胞(MDSC)と腫瘍制御

柴田昌彦, 権田憲士, 三村耕作, 河野浩二, 大戸斉, 竹之下誠一

炎症と免疫 26 ( 2 ) 115 - 121 2018.2（ ISSN:0918-8371 ）

Augmentation of antibody-dependent cellular cytotoxicity with defucosylated monoclonal antibodies in patients with GI-tract cancer.

Nakajima T, Okayama H, Ashizawa M, Noda M, Aoto K, Saito M, Monma T, Ohki S, Shibata M, Takenoshita S, Kono K

Oncology letters 15 ( 2 ) 2604 - 2610 2018.2（ ISSN:1792-1074 ）

Decreased expression of CADM1 and CADM4 are associated with advanced stage breast cancer.

Saito M, Goto A, Abe N, Saito K, Maeda D, Ohtake T, Murakami Y, Takenoshita S

Oncology letters 15 ( 2 ) 2401 - 2406 2018.2（ ISSN:1792-1074 ）

Enhanced expression of KIF4A in colorectal cancer is associated with lymph node metastasis.

Matsumoto Y, Saito M, Saito K, Kanke Y, Watanabe Y, Onozawa H, Hayase S, Sakamoto W, Ishigame T, Momma T, Kumamoto K, Ohki S, Takenoshita S

Oncology letters 15 ( 2 ) 2188 - 2194 2018.2（ ISSN:1792-1074 ）

Upregulated solute carrier family 37 member 1 in colorectal cancer is associated with poor patient outcome and metastasis.

Kikuchi D, Saito M, Saito K, Watanabe Y, Matsumoto Y, Kanke Y, Onozawa H, Hayase S, Sakamoto W, Ishigame T, Momma T, Ohki S, Takenoshita S

Oncology letters 15 ( 2 ) 2065 - 2072 2018.2（ ISSN:1792-1074 ）

Gene aberration profile of tumors of adolescent and young adult females.

Kanke Y, Shimomura A, Saito M, Honda T, Shiraishi K, Shimada Y, Watanabe R, Yoshida H, Yoshida M, Shimizu C, Takahashi K, Totsuka H, Ogiwara H, Hirose S, Kono K, Tamura K, Okamoto A, Kinoshita T, Kato T, Kohno T

Oncotarget 9 ( 5 ) 6228 - 6237 2018.1

癌免疫カンファレンスルーム(第5回)　免疫チェックポイント阻害薬の将来

河野浩二

消化器外科 41 ( 1 ) 69 - 75 2018.1（ ISSN:0387-2645 ）

Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy.

Saito M, Suzuki H, Kono K, Takenoshita S, Kohno T

Surgery today 48 ( 1 ) 1 - 8 2018.1（ ISSN:0941-1291 ）

PD-L1 expression is mainly regulated by interferon gamma associated with JAK-STAT pathway in gastric cancer.

Mimura K, Teh JL, Okayama H, Shiraishi K, Kua LF, Koh V, Smoot DT, Ashktorab H, Oike T, Suzuki Y, Fazreen Z, Asuncion BR, Shabbir A, Yong WP, So J, Soong R, Kono K

109 ( 1 ) 43 - 53 2018.1（ ISSN:1347-9032 ）

Immunogenic tumor cell death induced by chemotherapy in patients with breast cancer and esophageal squamous cell carcinoma.

Aoto K, Mimura K, Okayama H, Saito M, Chida S, Noda M, Nakajima T, Saito K, Abe N, Ohki S, Ohtake T, Takenoshita S, Kono K

Oncology reports 39 ( 1 ) 151 - 159 2018.1（ ISSN:1021-335X ）

Current status of cancer immunotherapy for esophageal squamous cell carcinoma.

Kono K, Mimura K, Yamada L, Ujiie D, Hayase S, Tada T, Hanayama H, Min AKT, Shibata M, Momma T, Saze Z, Ohki S

Esophagus 15 ( 1 ) 1 - 9 2018.1（ ISSN:1612-9059 ）

SIRS, CARS and MARS in relationship to cancer cachexia and its clinical implications.

Shibata M, Gonda K, Shimura T, Sakurai K, Takenoshita S

Annals of Cancer Research and Therapy 26 ( 1 ) 54 - 59 2018.1（ ISSN:1344-6835 ）

壊疽性膿皮症合併の潰瘍性大腸炎に対して陰圧閉鎖療法が寄与し得た1例

大木進司,岡山洋和,坂本渉,藤田正太郎,遠藤久仁,斎藤元伸,佐瀬善一郎,門馬智之,河野浩二

日本ストーマ・排泄リハビリテーション学会誌 34 ( 1 ) 290 2018.1

アネキシンA1はp53陽性胃癌で発現が亢進している(Annexin A1 is upregulated in p53-positive gastric cancer)

Saito Motonobu, Saito Katsuharu, Nakano Hiroshi, Kikuchi Tomohiro, Okayama Hirokazu, Fujita Shotaro, Endo Hisahito, Sakamoto Wataru, Momma Tomoyuki, Ohki Shinji, Kono Koji

Annals of Cancer Research and Therapy 26 ( 1 ) 26 - 30 2018.1（ ISSN:1344-6835 ）

A case of clinical complete response of colorectal liver metastasis following chemotherapy with S-1 and oxaliplatin (SOX) in combination with bevacizumab

Azuhata T, Shibata S, Nakamura K, Kawano D, Terakado Y, Azuhata I, Sakurai A, Yamada T, Sugita K, Tomita R, Tsuyama Y, Tanjoh K, Azuhata S

Annals of Cancer Research and Therapy 26 ( 2 ) 101 - 104 2018

A Nucleolar Stress-Specific p53-miR-101 Molecular Circuit Functions as an Intrinsic Tumor-Suppressor Network.

Fujiwara Y, Saito M, Robles AI, Nishida M, Takeshita F, Watanabe M, Ochiya T, Yokota J, Kohno T, Harris CC, Tsuchiya N.

EBioMedicine 33 33 - 48 2018

Angiogenesis: Managing the Culprits behind Tumorigenesis and Metastasis

Ashwaq Hamid Salem Yehya, Muhammad Asif, Sven Hans Petersen, Ayappa V. Subramaniam ID , Kono K, Amin Malik Shah Abdul Majid, Chern Ein Oon, ID

Medicina 54 ( 8 ) 2018

Prognostic role of FUT8 expression in relation to p53 status in stage II and III colorectal cancer.

Noda M, Okayama H, Kofunato Y, Chida S, Saito K, Tada T, Ashizawa M, Nakajima T, Aoto K, Kikuchi T, Sakamoto W, Endo H, Fujita S, Saito M, Momma T, Ohki S, Kono K

PloS one 13 ( 7 ) e0200315 2018

Annexin A1 is upregulated in p53-positive gastric cancer

Saito M, Saito K, Nakano H, Kikuchi T, Okayama H, Fujita S, Endo H, Sakamoto W, Momma T, Ohki S, Kono K

Annals of Cancer Research and Therapy 26 ( 1 ) 26 - 30 2018

Regulation on introducing process of the highly difficult new medical technologies: A survey on the current status of practice guidelines in Japan and overseas.

Minamikawa K, Okumura A, Kokudo N, Kono K

Biosci Trends 2018

Expression of kallikrein-related peptidase 13 is associated with poor prognosis in esophageal squamous cell carcinoma

Nohara K, Yamada K, Yamada L, Hagiwara T, Igari T, Yokoi C, Soma D, Yamashita S, Dohi T, Kawamura YI.

Gen Thorac Cardiovasc Surg 66 ( 6 ) 351 - 357 2018

An anti-ASCT2 monoclonal antibody suppresses gastric cancer growth by inducing oxidative stress and antibody dependent cellular toxicity in preclinical models

Osanai-Sasakawa A, Hosomi K, Sumitomo Y, Takizawa T, Tomura-Suruki S, Imaizumi M, Kasai N, Poh TW, Yamano K, Yong WP, Kono K, Nakamura S, Ishii T, Nakai R.

Am J Cancer Res 8 ( 8 ) 1499 - 1513 2018

Anticancer activities of a benzimidazole compound through sirtuin inhibition in colorectal cancer.

Tan YJ, Lee YT, Petersen SH, Kono K, Tan SC, Oon CE

Future Med Chem 10 ( 17 ) 2039 - 2057 2018

Tumor-specific CD8-positive T cell-mediated antitumor immunity is implicated in the antitumor effect of local hyperthermia.

Ando Ken, Suzuki Yoshiyuki, Kaminuma Takuya, Yoshimoto Yuya, Oike Takahiro, Okonogi Noriyuki, Sato Hiro, Tamaki Tomoaki, Noda Shin-Ei, Mimura Kosaku, Nakano

International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 35 ( 1 ) 226 - 231 2018（ ISSN:0265-6736 ）

Acquired Resistance to FGFR Inhibitor in Diffuse-Type Gastric Cancer through an AKT-Independent PKC-Mediated Phosphorylation of GSK3β

Lau WM, Teng E, Huang KK, Tan JW, Das K, Zang Z, Chia T, Teh M, Kono K, Yong WP, Shabbir A, Tay A, Phua NS, Tan P, Chan SL, So JBY.

Mol Cancer Ther 17 ( 1 ) 232 - 242 2018

The intratumoral distribution influences the prognostic impact of CD68- and CD204-positive macrophages in non-small cell lung cancer

Li Z, Maeda D, Yoshida M, Umakoshi M, Nanjo H, Shiraishi K, Saito M, Kohno T, Konno H, Saito H, Minamiya Y, Goto A

Lung Cancer 123 127 - 135 2018

術野の消毒

大木進司, 河野浩二

5年でマスター消化器外科標準手術　消化器外科専門医への道 6 - 9 2018

TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis.

Ando J, Saito M, Imai JI, Ito E, Yanagisawa Y, Honma R, Saito K, Tachibana K, Momma T, Ohki S, Ohtake T, Watanabe S, Waguri S, Kono K, Takenoshita S

Fukushima journal of medical science 63 ( 3 ) 141 - 151 2017.12（ ISSN:0016-2590 ）

IL-17 and VEGF are increased and correlated to systemic inflammation, immune suppression, and malnutrition in patients with breast cancer

Tachibana K., Shibata M., Gonda K., Matsumoto Y., Nakajima T., Abe N., Ohtake T., Ohto H., Kono K., Takenoshita S.

European Journal of Inflammation 15 ( 3 ) 219 - 228 2017.12（ ISSN:1721727X ）

手術手技　食道癌切除後胃管再建不能例における有茎空腸再建術

大木進司, 佐瀬善一郎, 早瀬傑, 花山寛之, 多田武志, 河野浩二

手術 71 ( 13 ) 1789 - 1792 2017.12（ ISSN:0037-4423 ）

TBX19 is overexpressed in colorectal cancer and associated with lymph node metastasis(和訳中)

Ando Jin, Saito Motonobu, Imai Jun-ichi, Ito Emi, Yanagisawa Yuka, Honma Reiko, Saito Katsuharu, Tachibana Kazunoshin, Momma Tomoyuki, Ohki Shinji, Ohtake Tohru, Watanabe Shinya, Waguri Satoshi, Kono Koji, Takenoshita Seiichi

Fukushima Journal of Medical Science 63 ( 3 ) 141 - 151 2017.12（ ISSN:0016-2590 ）

外傷性横隔膜ヘルニアおよび卵巣嚢腫破裂に対して腹腔鏡下手術を施行した1例

花山寛之,佐瀬善一郎,金田晃尚,早瀬傑,門馬智之,大木進司,河野浩二

日本内視鏡外科学会雑誌 22 ( 7 ) EP228-07 2017.12

DNA double-strand break repair pathway regulates PD-L1 expression in cancer cells.

Sato H, Niimi A, Yasuhara T, Permata TBM, Hagiwara Y, Isono M, Nuryadi E, Sekine R, Oike T, Kakoti S, Yoshimoto Y, Held KD, Suzuki Y, Kono K, Miyagawa K, Nakano T, Shibata A

Nature communications 8 ( 1 ) 1751 2017.11

Adaptation of anti-PD-1/anti-PD-L1 antibody from the viewpoint of analysis of tumor microenvironment

Mimura K., Nakayama Y., Nakazawa T., Kono K.

Japanese Journal of Cancer and Chemotherapy 44 ( 11 ) 981 - 983 2017.11（ ISSN:03850684 ）

【がん局所微小環境と免疫療法】腫瘍微小環境の解析から診た抗PD-1/抗PD-L1抗体の適応

三村耕作, 中山裕子, 中澤匡男, 河野浩二

癌と化学療法 44 ( 11 ) 981 - 983 2017.11（ ISSN:0385-0684 ）

[Adaptation of Anti-PD-1/Anti-PD-L1 Antibody from the Viewpoint of Analysis of Tumor Microenvironment].

Mimura K, Nakayama Y, Nakazawa T, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 44 ( 11 ) 981 - 983 2017.11（ ISSN:0385-0684 ）

The genomic and epigenomic landscape in thymic carcinoma.

Saito M, Fujiwara Y, Asao T, Honda T, Shimada Y, Kanai Y, Tsuta K, Kono K, Watanabe S, Ohe Y, Kohno T

Carcinogenesis 38 ( 11 ) 1084 - 1091 2017.10（ ISSN:0143-3334 ）

Regulation of PD-L1 by microRNA in mismatch repair deficient-colorectal cancer

Ashizawa M., Okayama H., Min A., Noda M., Aoto K., Nakajima T., Ishigame T., Mimura K., Kono K.

Japanese Journal of Cancer and Chemotherapy 44 ( 10 ) 889 - 891 2017.10（ ISSN:03850684 ）

ミスマッチ修復機構欠損を有する大腸癌におけるMicroRNAによるPD-L1制御機構

芦澤舞, 岡山洋和, Aung Kyi Thar Min, 野田勝, 青砥慶太, 中島隆宏, 石亀輝英, 三村耕作, 河野浩二

癌と化学療法 44 ( 10 ) 889 - 891 2017.10（ ISSN:0385-0684 ）

長期生存を認めた原発不明癌の3症例

権田憲士, 柴田昌彦, 安田政実, 立谷陽介, 畠山優一, 河野浩二, 六角裕一

癌と化学療法 44 ( 10 ) 950 - 952 2017.10（ ISSN:0385-0684 ）

化学療法によりpCRが得られた直腸癌の2症例

権田憲士, 立谷陽介, 畠山優一, 柴田昌彦, 河野浩二, 六角裕一

癌と化学療法 44 ( 10 ) 944 - 946 2017.10（ ISSN:0385-0684 ）

[Regulation of PD-L1 by MicroRNA in Mismatch Repair Deficient-Colorectal Cancer].

Ashizawa M, Okayama H, Aung Kyi Thar Min, Noda M, Aoto K, Nakajima T, Ishigame T, Mimura K, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 44 ( 10 ) 889 - 891 2017.10（ ISSN:0385-0684 ）

Clinical Significance of Soluble Intercellular Adhesion Molecule-1 and Interleukin-6 in Patients with Extrahepatic Cholangiocarcinoma.

Shimura T, Shibata M, Gonda K, Kofunato Y, Okada R, Ishigame T, Kimura T, Kenjo A, Marubashi S, Kono K, Takenoshita S

Journal of investigative surgery : the official journal of the Academy of Surgical Research 1 - 8 2017.9（ ISSN:0894-1939 ）

Therapeutic cancer vaccine and immune checkpoint inhibitor

Mimura K., Kono K.

Japanese Journal of Cancer and Chemotherapy 44 ( 9 ) 733 - 736 2017.9（ ISSN:03850684 ）

Significance of Circulating Galectin-3 in Patients with Pancreatobiliary Cancer.

Shimura T, Shibata M, Gonda K, Kofunato Y, Okada R, Ishigame T, Kimura T, Kenjo A, Kono K, Marubashi S

Anticancer research 37 ( 9 ) 4979 - 4986 2017.9（ ISSN:0250-7005 ）

若き外科医からの提言　わたしたちの将来の外科医療を見据えて　新米外科教授からの提言　医学生教育、外科専門医研修に主眼をおいた外科学講座再編　福島の新たな挑戦

木村隆, 鈴木眞一, 河野浩二, 丸橋繁, 鈴木弘行, 大竹徹, 田中秀明, 横山斉, 後藤満一, 竹之下誠一

日本外科学会雑誌 118 ( 5 ) 593 - 596 2017.9（ ISSN:0301-4894 ）

【複合がん免疫療法】がんワクチンと免疫チェックポイント阻害剤

三村耕作, 河野浩二

癌と化学療法 44 ( 9 ) 733 - 736 2017.9（ ISSN:0385-0684 ）

[Therapeutic Cancer Vaccine and Immune Checkpoint Inhibitor].

Mimura K, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 44 ( 9 ) 733 - 736 2017.9（ ISSN:0385-0684 ）

IL-17 and VEGF are significantly associated with disease progression involving systemic inflammation in patients with gastric and colorectal cancers(和訳中)

Minamikawa Kazuo, Shibata Masahiko, Gonda Kenji, Ujiie Daisuke, Ashizawa Mai, Nakajima Takahiro, Okayama Hirokazu, Sakamoto Wataru, Saito Motonobu, Momma Tomoyuki, Mimura Kousaku, Ohki Shinji, Shimura Tatsuo, Ohto Hitoshi, Takenoshita Seiichi, Kono Koji

Annals of Cancer Research and Therapy 25 ( 2 ) 67 - 76 2017.8（ ISSN:1344-6835 ）

デヴィータがんの分子生物学第2版

岡山洋和, 河野浩二, 竹之下誠一(翻訳)

メディカルサイエンスインターナショナル 19 2017.6

手術手技　縦隔内限局型特発性食道破裂に対する経腹的胃底部縫着術

多田武志, 佐瀬善一郎, 花山寛之, 丸橋繁, 河野浩二, 後藤満一

手術 71 ( 7 ) 1077 - 1081 2017.6（ ISSN:0037-4423 ）

胃癌　化学療法

河野　浩二

日本外科学会雑誌 118 ( 3 ) 351 - 353 2017.5

Upregulation of thioredoxin-1 in activated human NK cells confers increased tolerance to oxidative stress.

Mimura K, Kua LF, Shimasaki N, Shiraishi K, Nakajima S, Siang LK, Shabbir A, So J, Yong WP, Kono K

Cancer immunology, immunotherapy : CII 66 ( 5 ) 605 - 613 2017.5（ ISSN:0340-7004 ）

胃癌　化学療法

河野浩二

日本外科学会雑誌 118 ( 3 ) 351 - 353 2017.5（ ISSN:0301-4894 ）

Treatment of lung adenocarcinoma by molecular-targeted therapy and immunotherapy.

Saito M, Suzuki H, Kono K, Takenoshita S, Kohno T

Surgery today 2017.3（ ISSN:0941-1291 ）

Evaluation of LECS for GIST of the stomach

89 475 2017.3

Intraperitoneal chemotherapy for gastric cancer with peritoneal disease: experience from Singapore and Japan.

Kono K, Yong WP, Okayama H, Shabbir A, Momma T, Ohki S, Takenoshita S, So J

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20 ( Suppl 1 ) 122 - 127 2017.3（ ISSN:1436-3291 ）

腹膜障害を伴う胃癌に対する腹腔内化学療法　シンガポールと日本での経験(Intraperitoneal chemotherapy for gastric cancer with peritoneal disease: experience from Singapore and Japan)

Kono Koji, Yong Wei-Peng, Okayama Hirokazu, Shabbir Asim, Momma Tomoyuki, Ohki Shinji, Takenoshita Seiichi, So Jimmy

Gastric Cancer 20 ( Suppl.1 ) S122 - S127 2017.3（ ISSN:1436-3291 ）

側方転移を伴う局所進行直腸癌に対して5FU/Oxaliplatin併用術前化学放射線療法にてCRとなった症例経験

高和正, 赤須孝之, 隈元謙介, 月田茂之, 早瀬傑, 藤田正太郎, 門馬智之, 大木進司, 河野浩二, 竹之下誠一

日本大腸肛門病学会雑誌 70 ( 2 ) 123 2017.2

がんワクチンと免疫チェックポイント阻害剤

三村耕作,河野浩二

癌と化学療法 2017

Regulation of PD-L1 by microRNA in mismatch repair deficient colorectal cancer

芦澤舞, 岡山洋和, Aun Kyi Thar Min, 野田勝, 青砥慶太, 中島隆宏, 石亀輝英, 河野浩二

Annual Meeting of Japanese Research Society of Surgical Cancer Immunology 38 66 2017

消化管癌患者における脱フコシル化抗体を用いたADCC活性の解析

中島隆宏, 芦澤舞, 千田峻, 野田勝, 青砥慶太, 岡山洋和, 斎藤元伸, 志村龍男, 柴田昌彦, 丸橋繁, 河野浩二

癌免疫外科研究会プログラム・抄録集 38 44 - 44 2017

胃癌における抗PD-1抗体 / 抗PD-L1抗体の適応症例の検討

三村耕作, 白石謙介, 河野浩二

癌免疫外科研究会プログラム・抄録集 38 82 - 82 2017

乳癌における抗PD-1抗体 / 抗PD-L1抗体適応症例の検討

中山裕子, 三村耕作, 大森征人, 木村亜矢子, 井上正行, 河野浩二, 井上慎吾

癌免疫外科研究会プログラム・抄録集 38 81 - 81 2017

乳癌, 食道癌における化学療法が惹起するImmunogenic tumor cell deathの検討

青砥慶太, 河野浩二, 野田勝, 中島隆宏, 岡山洋和, 阿部宣子, 大木進司, 大竹徹

癌免疫外科研究会プログラム・抄録集 38 85 - 85 2017

化学療法によりCRが得られた直腸癌の2例

権田憲士, 畠山裕一, 立谷陽介, 柴田昌彦, 河野浩二, 六角裕一

癌免疫外科研究会プログラム・抄録集 38 129 - 129 2017

放射線治療における抗腫瘍免疫の役割とその増強

吉本由哉、鈴木義行、三村耕作、河野浩二、中野隆史

日本免疫治療学研究会学術集会プログラム・抄録集 14 46 2017

Significance of Circulating Galectin-3 in Patients with Hepato-biliary and Pancreatic Cancer

SHIMURA Tatsuo, SHIBATA Masahiko, KOFUNATO Yasuhide, ISHIGAME Teruhide, OKADA Ryo, KIMURA Takashi, KENJO Akira, MARUBASHI Shigeru, OHKI Shinji, KONO Koji, TAKENOSHITA Seiichi

Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 78 ( 4 ) 633 - 637 2017（ ISSN:1345-2843 ）

IL-17 and VEGF are significantly associated with disease progression involving systemic inflammation in patients with gastric and colorectal cancers

Ａｎｎａｌｓ　ｏｆ　Ｃａｎｃｅｒ　Ｒｅｓｅａｒｃｈ　ａｎｄ　Ｔｈｅｒａｐｙ 25 ( 2 ) 67 - 76 2017

Anti-tumor efficacy evaluation of a novel monoclonal antibody targeting neutral amino acid transporter ASCT2 using patient-derived xenograft mouse models of gastric cancer.

Kasai N, Sasakawa A, Hosomi K, Poh TW, Chua BL, Yong WP, So J, Chan SL, Soong R, Kono K*, Ishii T, Yamano K.

Am J Transl Res. 9 ( 7 ) 3399 - 3410 2017

癌免疫カンファレンスルーム、連載の開始にあたって

柴田昌彦, 河野浩二

消化器外科 40 ( 10 ) 1474 - 1476 2017

胃体上部後壁病変に対する腹腔鏡内視鏡合同手術(LECS)における手技の工夫

門馬智之, 加瀬晃志, 早瀬傑, 藤田正太郎, 坂本渉, 高和正, 大木進司, 河野浩二, 竹之下誠一

日本内視鏡外科学会雑誌 21 ( 7 ) OS96-2 2016.12

出血を繰り返した小腸腫瘍に対し単孔式腹腔鏡下手術を行った一例

加瀬晃志, 早瀬傑, 高和正, 坂本渉, 藤田正太郎, 門馬智之, 大木進司, 河野浩二

日本内視鏡外科学会雑誌 21 ( 7 ) DP7 - 9 2016.12

可吸収性止血剤を使用した腹腔鏡下結腸切除術後に腹腔内膿瘍をきたした1例

早瀬傑, 加瀬晃志, 坂本渉, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二

日本内視鏡外科学会雑誌 21 ( 7 ) DP57-5 2016.12

Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility.

Shiraishi K, Mimura K, Kua LF, Koh V, Siang LK, Nakajima S, Fujii H, Shabbir A, Yong WP, So J, Takenoshita S, Kono K

Journal of gastroenterology 51 ( 12 ) 1101 - 1111 2016.12（ ISSN:0944-1174 ）

胃癌におけるMMP活性の抑制は、NKG2Dリガンド発現を回復させ、NK細胞感受性を改善することができる(Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility)

Shiraishi Kensuke, Mimura Kousaku, Kua Ley-Fang, Koh Vivien, Siang Lim Kee, Nakajima Shotaro, Fujii Hideki, Shabbir Asim, Yong Wei-Peng, So Jimmy, Takenoshita Seiichi, Kono Koji

Journal of Gastroenterology 51 ( 12 ) 1101 - 1111 2016.12（ ISSN:0944-1174 ）

Accumulation of CD11c+CD163+ Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity.

Nakajima S, Koh V, Kua LF, So J, Davide L, Lim KS, Petersen SH, Yong WP, Shabbir A, Kono K

Journal of immunology (Baltimore, Md. : 1950) 197 ( 9 ) 3735 - 3745 2016.11（ ISSN:0022-1767 ）

A Case of Port Site Recurrence after Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer

Fujita S., Ohki S., Kase K., Yamauchi N., Chida S., Hayase S., Sakamoto W., Monma T., Takawa M., Ohtake T., Kono K., Takenoshita S.

Gan to kagaku ryoho. Cancer & chemotherapy 43 ( 12 ) 1502 - 1504 2016.11（ ISSN:03850684 ）

Risk Evaluation and Prognostic Prediction of Colorectal Cancer in Elderly Patients Over 80 Years of Age

Ohki S., Kase K., Chida S., Hayase S., Fujita S., Monma T., Takawa M., Kono K., Ohtake T., Takenoshita S.

Gan to kagaku ryoho. Cancer & chemotherapy 43 ( 12 ) 1532 - 1534 2016.11（ ISSN:03850684 ）

80歳以上の高齢者大腸癌におけるリスク評価と予後の解析

大木進司, 加瀬晃志, 千田峻, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 河野浩二, 大竹徹, 竹之下誠一

癌と化学療法 43 ( 12 ) 1532 - 1534 2016.11（ ISSN:0385-0684 ）

腹腔鏡下幽門側胃切除術後のポートサイト再発を来した高齢者胃癌の1例

藤田正太郎, 大木進司, 加瀬晃志, 山内直人, 千田峻, 早瀬傑, 坂本渉, 門馬智之, 高和正, 大竹徹, 河野浩二, 竹之下誠一

癌と化学療法 43 ( 12 ) 1502 - 1504 2016.11（ ISSN:0385-0684 ）

[A Case of Port Site Recurrence after Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer].

Fujita S, Ohki S, Kase K, Yamauchi N, Chida S, Hayase S, Sakamoto W, Monma T, Takawa M, Ohtake T, Kono K, Takenoshita S

Gan to kagaku ryoho. Cancer & chemotherapy 43 ( 12 ) 1502 - 1504 2016.11（ ISSN:0385-0684 ）

[Risk Evaluation and Prognostic Prediction of Colorectal Cancer in Elderly Patients Over 80 Years of Age].

Ohki S, Kase K, Chida S, Hayase S, Fujita S, Monma T, Takawa M, Kono K, Ohtake T, Takenoshita S

Gan to kagaku ryoho. Cancer & chemotherapy 43 ( 12 ) 1532 - 1534 2016.11（ ISSN:0385-0684 ）

Intraperitoneal chemotherapy for gastric cancer with peritoneal disease: experience from Singapore and Japan

Koji Kono, Wei-Peng Yong, Hirokazu Okayama, Asim Shabbir, Tomoyuki Momma, Shinji Ohki, Seiichi Takenoshita & Jimmy So

Gastric Cancer 2016.10（ ISSN:1436-3291 ）

ハイリスクStage II大腸癌とその対策 Stage II大腸癌における予後予測因子としてのinflammatory-based markerの意義

大木進司, 加瀬晃志, 早瀬傑, 坂本渉, 藤田正太郎, 門馬智之, 高和正, 河野浩二, 大竹徹, 竹之下誠一

日本臨床外科学会雑誌 77 ( 増刊 ) 430 2016.10

大腸癌術後に高齢発症した潰瘍性大腸炎の1例

加瀬晃志, 高和正, 早瀬傑, 坂本渉, 藤田正太郎, 門馬智之, 大木進司, 河野浩二

日本臨床外科学会雑誌 77 ( 増刊 ) 882 2016.10

感染性心内膜炎の加療後に小腸間膜仮性動脈瘤破裂で腹腔内出血を来した1例

藤田正太郎, 加瀬晃志, 早瀬傑, 坂本渉, 門馬智之, 高和正, 大木進司, 河野浩二, 大竹徹

日本臨床外科学会雑誌 77 ( 増刊 ) 914 2016.10

CTで偶然発見され腹腔鏡補助下に切除した空腸異所性膵の1例

早瀬傑, 加瀬晃志, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二

日本臨床外科学会雑誌 77 ( 増刊 ) 939 2016.10

胃　胃がんにおける免疫療法の可能性胃癌症例における癌細胞のHLA class IとPD-L1の発現機構

三村耕作, 白石謙介, 河野浩二

日本癌治療学会学術集会抄録集 54回 MS61-1 2016.10

大腸バイオマーカー消化器癌患者における血清中IL-18濃度の予後における検討

権田憲士, 柴田昌彦, 門馬智之, 鈴木聡, 坂本渉, 小舟戸康秀, 岡田良, 石亀輝秀, 大木進司, 志村龍男, 河野浩二, 竹之下誠一

日本癌治療学会学術集会抄録集 54回 WS39-2 2016.10

放射線治療における抗腫瘍免疫の役割とその増強

吉本由哉, 鈴木義行, 三村耕作, 河野浩二, 中野隆史

日本癌治療学会学術集会抄録集 54回 P24-3 2016.10

The mechanism of HLA class I and PD-L1 expression of cancer cells in tumor microenvironment

Mimura K., Shiraishi K., Kobayashi M., Kono T., Kono K.

Japanese Journal of Cancer and Chemotherapy 43 ( 9 ) 1027 - 1029 2016.9（ ISSN:03850684 ）

【抗PD-1抗体の基礎と臨床】腫瘍微小環境における癌細胞上のHLA Class IとPD-L1の調節機構

三村耕作, 白石謙介, 小林正史, 河野哲夫, 河野浩二

癌と化学療法 43 ( 9 ) 1027 - 1029 2016.9

The expression of glycogenes identifies a distinct subtype of colorectal cancer

66 ( 3 ) 132 2016.9

【抗PD-1抗体の基礎と臨床】腫瘍微小環境における癌細胞上のHLA Class IとPD-L1の調節機構

三村耕作, 白石謙介, 小林正史, 河野哲夫, 河野浩二

癌と化学療法 43 ( 9 ) 1027 - 1029 2016.9（ ISSN:0385-0684 ）

胸部食道切除後の有茎空腸再建術の有用性

河野浩二, 大木進司, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 藤井秀樹, 竹之下誠一

日本食道学会学術集会プログラム・抄録集 70 ( 110 ) 2016.7

食道癌に対する化学放射線療法の治療効果および予後予測に関する検討

大木進司, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 河野浩二, 竹之下誠一

日本食道学会学術集会プログラム・抄録集 70回 88 2016.7

胸部食道切除後の有茎空腸再建術の有用性

河野浩二, 大木進司, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 藤井秀樹, 竹之下誠一

日本食道学会学術集会プログラム・抄録集 70回 110 2016.7

胸部食道癌術後11年目に再建胃管に発生した胃管癌の1例

早瀬傑, 月田茂之, 山内直人, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二, 竹之下誠一

日本食道学会学術集会プログラム・抄録集 70回 133 2016.7

stage II/III下部直腸癌に対する術前放射線治療の功罪と個別化に関する検討

大木進司, 隈元謙介, 早瀬傑, 藤田正太郎, 門馬智之, 岡山洋和, 高和正, 河野浩二, 竹之下誠一

日本消化器外科学会総会 71回 P1-40-2 2016.7

胃管再建不能例における胸部食道切除後の有茎空腸再建術の有用性

河野浩二, 大木進司, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 藤井秀樹, 竹之下誠一

日本消化器外科学会総会 71回 P2-6-1 2016.7

切除困難なS状結腸癌に対して術前FOLFOXIRI+ベバシズマブ療法が奏功した1例

早瀬傑, 月田茂之, 山内直人, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二, 竹之下誠一

日本消化器外科学会総会 71回 P2-51-7 2016.7

胃管再建不能例における胸部食道切除後の有茎空腸再建術の有用性

河野浩二, 大木進司, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 藤井秀樹, 竹之下誠一

日本消化器外科学会総会 71 P2-6-1 2016.7

乳癌における化学療法が惹起するImmunogenic tumor cell deathの検討

青砥慶太, 河野浩二, 千田峻, 野田勝, 中島隆宏, 岡山洋和, 阿部宣子, 立花和之進, 岡野舞子, 大木進司, 大竹徹, 竹之下誠一

日本乳癌学会総会プログラム抄録集 24回 543 2016.6

がんのバイオマーカーと分子標的治療癌ワクチン療法+抗PD1抗体治療の臨床応用の開発

河野浩二, 三村耕作, 岡山洋和, 中島隆宏, 白石謙介, アウン・チー , 藤田正太郎, 早瀬傑, 門馬智之, 高和正, 大木進司, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PD-10-3 2016.4

苛性ソーダによる腐食性食道炎の2手術症例

早瀬傑, 河野浩二, 大木進司, 藤田正太郎, 門馬智之, 月田茂之, 高和正, 藤井秀樹, 竹之下誠一

日本気管食道科学会会報 67 ( 2 ) 94 2016.4

胃癌におけるMMP活性の阻害がNK細胞傷害活性に与える影響について

白石謙介, 三村耕作, 小林正史, 河野哲夫, 藤井秀樹, 河野浩二

日本外科学会定期学術集会抄録集 116回 PS-028-8 2016.4

Barrett食道癌の臨床病理学的特徴と治療戦略

大木進司, 河野浩二, 月田茂之, 早瀬傑, 藤田正太郎, 岡山洋和, 門馬智之, 高和正, 大竹徹, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-032-3 2016.4

消化器がんにおけるPDL1調節機構の解明

中島隆宏, Kyi Aung, 三村耕作, 白石謙介, 千田峻, 野田勝, 青砥慶太, 岡山洋和, 志村龍男, 大木進司, 大竹徹, 河野浩二, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-030-7 2016.4

散発性大腸癌におけるミスマッチ修復タンパク免疫染色の意義

門馬智之, 大木進司, 月田茂之, 早瀬傑, 岡山洋和, 藤田正太郎, 高和正, 河野浩二, 大竹徹, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-134-7 2016.4

乳癌、食道癌における化学療法が惹起するImmunogenic tumor cell deathの検討

青砥慶太, 河野浩二, 千田峻, 野田勝, 中島隆宏, 岡山洋和, 阿部宣子, 大木進司, 大竹徹, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-108-5 2016.4

Stromal gene expression contributes to poor prognosis in stage II-III colorectal cancer

PS-139-5 2016.4

がんのバイオマーカーと分子標的治療癌ワクチン療法+抗PD1抗体治療の臨床応用の開発

河野浩二, 三村耕作, 岡山洋和, 中島隆宏, 白石謙介, アウン・チー , 藤田正太郎, 早瀬傑, 門馬智之, 高和正, 大木進司, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PD-10-3 2016.4

The expression of glycogenes identifies a distinct subtype of colorectal cancer

PS-140-1 2016.4

Stem Cell Antigen 1陽性の間葉細胞は甲状腺再生時において濾胞細胞の起源となる

早瀬傑, 月田茂之, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-087-8 2016.4

胃癌における免疫チェックポイント阻害薬の適応とその応用について

三村耕作, 白石謙介, 河野浩二

日本外科学会定期学術集会抄録集 116回 OP-078-5 2016.4

局所進行直腸癌に対するFDG-PET/MRI診断の有用性とNeoadjuvant chemotherapyの可能性

高和正, 隈元謙介, 藤田正太郎, 早瀬傑, 月田茂之, 門馬智之, 大木進司, 河野浩二, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-223-8 2016.4

高齢者大腸癌における術前合併症および予後予測に関する検討

月田茂之, 大木進司, 早瀬傑, 藤田正太郎, 岡山洋和, 門馬智之, 高和正, 河野浩二, 大竹徹, 竹之下誠一

日本外科学会定期学術集会抄録集 116回 PS-220-4 2016.4

神経内分泌癌成分と腺癌成分が同時にリンパ節転移を来した食道胃接合部神経内分泌癌の1例

中島隆宏, 山内直人, 月田茂之, 千田峻, 野田勝, 岡山洋和, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 大木進司, 志村龍男, 河野浩二, 大竹徹, 鈴木理, 竹之下誠一

福島医学雑誌 66 ( 1 ) 18 - 23 2016.3

A Case that Neuroendocrine Carcinoma with Tubular Adenocarcinoma at Gastroesophageal Junction Metastasized to Lymph Node Simultaneously

66 ( 1 ) 18 - 23 2016.3

神経内分泌癌成分と腺癌成分が同時にリンパ節転移を来した食道胃接合部神経内分泌癌の1例

福島医学雑誌 66 ( 1 ) 18 - 23 2016.3

Therapeutic potential of natural killer cells for gastric cancer

361 2016.3

A case of advanced adenocarcinoma of esophagogastric junction responding to muttimodal therapy

403 2016.3

胃全摘術後、腹膜播種再発に対して姑息的手術をおこなった1例

高和正, 早瀬傑, 隈元謙介, 月田茂之, 藤田正太郎, 門馬智之, 矢澤貴, 大木進司, 河野浩二, 竹之下誠一

日本胃癌学会総会記事 88回 425 2016.3

A novel procedure in LECS for gastrointestinal stromal tumor

480 2016.3

消化器癌におけるPDL1-PD1を標的とした免疫療法の開発

河野浩二, 三村耕作, 竹之下誠一

日本消化器病学会雑誌 113 ( 臨増総会 ) Ａ257 2016.3

消化器癌におけるPDL1-PD1を標的とした免疫療法の開発

河野　浩二,三村　耕作,竹之下　誠一

日本消化器病学会雑誌 113 ( 臨時 ) Ａ257 2016.3

神経内分泌癌成分と腺癌成分が同時にリンパ節転移を来した食道胃接合部神経内分泌癌の1例

福島医学雑誌 66 ( 1 ) 18 - 23 2016.3（ ISSN:0016-2582 ）

胃癌におけるMAPK阻害薬と癌免疫療法効果

白石謙介, 三村耕作, 小林正史, 河野哲夫, 藤井秀樹, 河野浩二

山梨医学 43 187 2016.2

Intraperitoneal chemotherapy for gastric cancer with peritoneal disease from Singaporeand Japanese experience.

1. Koji Kono, Wei-Peng Yong, Hirokazu Okayama, Asim Shabbir, Tomoyuki Momma, Shinji Ohki, Seiichi Takenoshita and Jimmy So

Gastric cancer 2016

Enterotomy closure using knotless and barbed suture in laparoscopic upper gastrointestinal surgeries

6. Theresa Bautista, Asim Shabbir, Jaideepraj Rao, Jimmy So, Koji Kono, Pradeep Durai

Surgical Endoscopy 30 1699 - 1703 2016

Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK susceptibility.

5. Kensuke Shiraishi, Kousaku Mimura, Ley-Fang Kua, Vivien Koh, Lim Kee Siang, Shotaro Nakajima, Hideki Fujii, Asim Shabbir, Wei-Peng Yong, Jimmy So, Seiichi Takenoshita, Koji Kono.　

Journal of Gastroenterology 51 1101 - 1111 2016

PRL3-zumab, a first-in-class humanized antibody for cancer therapy.

4. Min Thura, Abdul Qader Omer Al-Aidaroos, Wei Peng Yong, Koji Kono, Abhishek Gupta, You Bin Lin, Kousaku Mimura, Jean Paul Thiery, Boon Cher Goh, Patrick Tan, Ross Soo, Cheng William Hong, Lingzhi Wang, Suling Joyce Lin, Elya Chen, Sun Young Rha, Hyun Cheol Chung, Jie Li, Sayantani Nandi, Hiu Fung Yuen, Shu-Dong Zhang, Yeoh Khay Guan, Jimmy So, and Qi Zeng

JCI insight 1 e87607 2016

腫瘍微小環境における癌細胞上のHLA　class IとPD-L1の調節機構

三村耕作, 白石謙介, 小林正史, 河野哲夫, 河野浩二

癌と化学療法 43 ( 9 ) 1027 - 1029 2016

80歳以上の高齢者大腸癌におけるリスク評価と予後の解析

大木進司, 加瀬晃志, 千田峻, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 河野浩二, 大竹徹, 竹之下誠一

日本癌局所療法研究会プログラム・抄録集 38 ( suppl ) 89 - 89 2016

ヒト腫瘍細胞へのX線および炭素イオン線照射によるHigh mobility group box 1 (HMGB 1) 放出量の比較

小此木範之, 鈴木義行, 吉本由哉, 尾池貴洋, 安藤謙, 佐藤浩央, 野田真永, 磯野真由, 三村耕作, 河野浩二, 鎌田正, 中野隆史

癌免疫外科研究会プログラム・抄録集 37 ( suppl ) 90 - 90 2016

放射線治療における抗腫瘍免疫の役割とその増強

吉本由哉, 鈴木義行, 三村耕作, 小此木範之, 佐藤浩央, 河野浩二, 中野隆史

癌免疫外科研究会プログラム・抄録集 37 ( suppl ) 91 - 91 2016

脱フコシル化 (Potelligent) 抗体を用いたADCC活性の解析

中島隆宏, 河野浩二, 千田峻, 野田勝, 青砥慶太, 立花和之進, 岡山洋和, 早瀬傑, 大竹徹, 竹之下誠一

癌免疫外科研究会プログラム・抄録集 37 ( suppl ) 55 - 55 2016

癌微小環境におけるMMP9の発現とNKG2Dリガンドの発現について

白石謙介, 三村耕作1, 藤井秀樹2, 河野浩二

癌免疫外科研究会プログラム・抄録集 37 ( suppl ) 124 - 124 2016

癌微小環境におけるPD-L1発現機構の解明について

三村耕作, 白石謙介, 河野浩二

癌免疫外科研究会プログラム・抄録集 37 ( suppl ) 62 - 62 2016

乳癌, 食道癌における化学療法が惹起するImmunogenic tumor cell deathの検討

青砥慶太, 河野浩二, 千田峻, 野田勝, 中島隆宏, 岡山洋和, 阿部宣子, 大木進司, 大竹徹, 竹之下誠一

癌免疫外科研究会プログラム・抄録集 37 ( suppl ) 123 - 123 2016

脱フコシル化抗体を用いたADCC活性の解析

中島隆宏, 芦澤舞, 野田勝, 青砥慶太, 立花和之進, 岡山洋和, 早瀬傑, 坂本渉, 石亀輝英, 齋藤元伸, 志村龍男, 河野浩二, 竹之下誠一

日本バイオセラピィ学会学術集会総会プログラム・抄録集 29 46 - 46 2016

腹腔鏡下幽門側胃切除術後のポート再発を来した高齢者胃癌の1例

藤田正太郎, 山内直人, 千田峻, 早瀬傑, 門馬智之, 高和正, 大木進司, 河野浩二, 竹之下誠一

日本癌局所療法研究会プログラム・抄録集 38 ( suppl ) 84 - 84 2016

苛性ソーダによる腐食性食道炎の2手術症例

早瀬傑, 河野浩二, 大木進司, 藤田正太郎, 門馬智之, 月田茂之, 高和正, 藤井秀樹, 竹之下誠一

日本気管食道科学会会報 67 ( 2 ) 5094 - 5094 2016

Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility

Shiraishi Kensuke、Mimura Kousaku、Kua Ley-Fang、Koh Vivien、Siang Lim Kee,Nakajima Shotaro,Fujii Hideki,Shabbir Asim,Yong Wei-Peng,So Jimmy,Takenoshita SeiichiKono Koji,

Journal of Gastroenterology 51 ( 12 ) 1101 - 1111 2016

Stromal VCAN expression as a potential prognostic biomarker for disease recurrence in stage II–III colon cancer

Shun Chida, Hirokazu Okayama, Masaru Noda, Katsuharu Saito, Takahiro Nakajima, Keita Aoto, Suguru Hayase, Tomoyuki Momma, Shinji Ohki, Koji Kono, and Seiichi Takenoshita

Carcinogenesis 37 ( 9 ) 878 - 887 2016

胃十二指腸病変に対する腹腔鏡内視鏡合同手術(LECS)の工夫と治療成績

大木進司, 門馬智之, 矢澤貴, 月田茂之, 早瀬傑, 藤田正太郎, 高和正, 河野浩二, 竹之下誠一

日本内視鏡外科学会雑誌 20 ( 7 ) OS261-8 2015.12

肛門管癌術後、2年6ヵ月後に側方リンパ節再発した1例

月田茂之, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二, 竹之下誠一

東北医学雑誌 127 ( 2 ) 182 - 183 2015.12

LDGにおける切離線決定に術中エコーは有用である

矢澤貴, 大木進司, 藤田正太郎, 門馬智之, 高和正, 隈元謙介, 河野浩二, 竹之下誠一

日本内視鏡外科学会雑誌 20 ( 7 ) OS161-4 2015.12

当科における進行大腸癌に対する腹腔鏡手術の治療成績

門馬智之, 大木進司, 月田茂之, 早瀬傑, 藤田正太郎, 高和正, 河野浩二, 竹之下誠一

日本内視鏡外科学会雑誌 20 ( 7 ) OS161-4 2015.12

腹腔鏡下にて治療し得た成人Bochdalekヘルニアの1例

早瀬傑, 月田茂之, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二, 竹之下誠一

日本内視鏡外科学会雑誌 20 ( 7 ) OS202-7 2015.12

Curative Surgery for Advanced Gastric Cancer with Extensive Lymph Node Metastasis after Long-Term Chemotherapy

Fujita S., Monma T., Ohki S., Murakami Y., Okayama H., Yazawa T., Takawa M., Kumamoto K., Ohtake T., Kono K., Takenoshita S.

Gan to kagaku ryoho. Cancer & chemotherapy 42 ( 12 ) 1668 - 1670 2015.11（ ISSN:03850684 ）

注射用メトロニダゾールが有効であったと考えられた消化器系感染症の2症例

高和正, 隈元謙介, 早瀬傑, 中島隆宏, 藤田正太郎, 大木進司, 河野浩二, 竹之下誠一

日本外科感染症学会雑誌 12 ( 5 ) 594 2015.11

Stage IV胃癌に対する化学療法後、手術に移行できた1例

藤田正太郎, 門馬智之, 大木進司, 村上祐子, 岡山洋和, 矢澤貴, 高和正, 隈元謙介, 大竹徹, 河野浩二, 竹之下誠一

癌と化学療法 42 ( 12 ) 1668 - 1670 2015.11

Stage IV胃癌に対する化学療法後、手術に移行できた1例

藤田正太郎, 門馬智之, 大木進司, 村上祐子, 岡山洋和, 矢澤貴, 高和正, 隈元謙介, 大竹徹, 河野浩二, 竹之下誠一

癌と化学療法 42 ( 12 ) 1668 - 1670 2015.11（ ISSN:0385-0684 ）

[Curative Surgery for Advanced Gastric Cancer with Extensive Lymph Node Metastasis after Long-Term Chemotherapy].

Fujita S, Monma T, Ohki S, Murakami Y, Okayama H, Yazawa T, Takawa M, Kumamoto K, Ohtake T, Kono K, Takenoshita S

Gan to kagaku ryoho. Cancer & chemotherapy 42 ( 12 ) 1668 - 70 2015.11（ ISSN:0385-0684 ）

MAPK経路の阻害によるMHC class I調節機序

河野浩二, 三村耕作, 白石謙介, 大木進司, 高和正, 門馬智之, 藤田正太郎, 矢澤貴, 竹之下誠一

日本癌学会総会記事Ｅ-1239 2015.10

十二指腸に嵌頓しBall valve syndromeを呈した胃GISTの一例

月田茂之, 大木進司, 村上祐子, 早瀬傑, 岡山洋和, 矢澤貴, 藤田正太郎, 門馬智之, 高和正, 河野浩二, 大竹徹, 竹之下誠一

日本臨床外科学会雑誌 76 ( 増刊 ) 1034 2015.10

腹腔鏡下胃切除術後にポート部再発をきたした胃癌の1例

：早瀬傑, 月田茂之, 藤田正太郎, 門馬智之, 高和正, 大木進司, 河野浩二

日本臨床外科学会雑誌 76 ( 増刊 ) 1029 2015.10

直腸癌低位前方切除術における縫合不全のリスク因子解析と治療成績向上に向けた取り組み

大木進司, 月田茂之, 早瀬傑, 藤田正太郎, 門馬智之, 高和正, 河野浩二, 竹之下誠一

日本臨床外科学会雑誌 76 ( 増刊 ) 582 2015.10

側方リンパ節転移を伴う下部進行直腸癌に対する新しい治療戦略

高和正, 隈元謙介, 赤須孝之, 早瀬傑, 藤田正太郎, 門馬智之, 月田茂之, 大木進司, 河野浩二, 竹之下誠一

日本臨床外科学会雑誌 76 ( 増刊 ) 531 2015.10

胃癌・大腸癌の腹膜播種に対する治療戦略腹膜播種を伴う進行胃癌に対する腹腔内Paclitaxel(PTX)+XEROX療法(第II相臨床試験)

河野浩二, 大木進司, 門馬智之, 藤田正太郎, 高和正, 早瀬傑, So Jimmy, Yong Wei-Peng, 竹之下誠一

日本臨床外科学会雑誌 76 ( 増刊 ) 442 2015.10

固形がん患者における癌悪液質の炎症を基盤とした免疫機構の検討

柴田昌彦, 権田憲士, 中村泉, 大木進司, 大竹徹, 志村龍男, 鈴木眞一, 河野浩二, 竹之下誠一

日本癌学会総会記事　74回 P-1074 2015.10

サルブリナルによるTNF-α誘発性NF-κB活性化のeIF2α非依存性阻害(eIF2α-Independent Inhibition of TNF-α-Triggered NF-κB Activation by Salubrinal)

Nakajima Shotaro, Chi Yuan, Gao Kun, Kono Koji, Yao Jian

Biological & Pharmaceutical Bulletin 38 ( 9 ) 1368 - 1374 2015.9（ ISSN:0918-6158 ）

局所再発直腸癌に対するFDG-PET/MRIによる画像診断の有用性

高和正, 赤須孝之, 隈元謙介, 石井士朗, 島尾大介, 原孝光, 中村泉, 大木進司, 河野浩二, 竹之下誠一

日本消化器外科学会総会 70回 P-178-1 2015.7

食道胃接合部に発生した神経内分泌細胞癌の2例

大木進司, 村上祐子, 岡山洋和, 矢澤貴, 藤田正太郎, 高和正, 隈元謙介, 河野浩二, 竹之下誠一

日本食道学会学術集会プログラム・抄録集 69回 163 2015.7

食道再建法・吻合法　最良の方法は胃管作成不能例に対する胸部食道切除後の有茎空腸再建術の有用性

河野浩二, 大木進司, 矢澤貢, 藤田正太郎, 村上祐子, 岡山洋和, 竹之下誠一, 河口賀彦, 赤池英憲, 藤井秀樹

日本食道学会学術集会プログラム・抄録集 69回 37 2015.7

消化管GISTの治療成績と臨床病理学的検討

大木進司, 矢澤貴, 門馬智之, 村上祐子, 岡山洋和, 藤田正太郎, 高和正, 隈元謙介, 河野浩二, 竹之下誠一

日本消化器外科学会総会 70回 RS-6-3 2015.7

高度進行胃癌の治療戦略腹膜播種を伴う進行胃癌に対する腹腔内Paclitaxel(PTX)+XEROX療法(第II相臨床試験)

河野浩二, So Jimmy, Asim Shabbir, Yong Wei-Peng, 矢澤貴, 藤田正太郎, 高和正, 隈元謙介, 大木進司, 竹之下誠一

日本消化器外科学会総会 70回 RS-6-3 2015.7

食道癌、胃癌におけるHLA ClassIの発現機構とMAPK pathwayについて

白石謙介, 三村耕作, 藤井秀樹, 河野浩二

日本消化器外科学会総会 70回 O-47-2 2015.7

腹膜播種を伴う進行再発胃癌に対するNK細胞療法の可能性について

三村耕作, 白石謙介, 小林正史, 河野浩二

日本消化器外科学会総会 70回 O-48-4 2015.7

直腸間膜原発Solitary fibrous tumorの1例

岡山洋和, 中島隆宏, 村上祐子, 矢澤貴, 藤田正太郎, 高和正, 隈元謙介, 大木進司, 河野浩二, 竹之下誠一

日本消化器外科学会総会 70回 P-144-1 2015.7

放射線療法により誘発される抗腫瘍免疫反応　レビュー(ANTI-TUMOR IMMUNE RESPONSES INDUCED BY RADIOTHERAPY: A REVIEW)

Yoshimoto Yuya, Kono Koji, Suzuki Yoshiyuki

Fukushima Journal of Medical Science 61 ( 1 ) 13 - 22 2015.7（ ISSN:0016-2590 ）

Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation.

Yoshimoto Y, Oike T, Okonogi N, Suzuki Y, Ando K, Sato H, Noda SE, Isono M, Mimura K, Kono K, Nakano T

Journal of radiation research 56 ( 3 ) 509 - 14 2015.5（ ISSN:0449-3060 ）

炭素イオンビームは免疫メディエータータンパク質、高移動群ボックス1の産生をX線照射と同等レベルで誘導する(Carbon-ion beams induce production of an immune mediator protein, high mobility group box 1, at levels comparable with X-ray irradiation)

Yoshimoto Yuya, Oike Takahiro, Okonogi Noriyuki, Suzuki Yoshiyuki, Ando Ken, Sato Hiro, Noda Shin-ei, Isono Mayu, Mimura Kousaku, Kono Koji, Nakano Takashi

Journal of Radiation Research 56 ( 3 ) 509 - 514 2015.5（ ISSN:0449-3060 ）

上部消化管腹膜播種を伴う高度進行胃癌に対する腹腔内Paclitaxel + XEROX化学療法の第II相臨床試験　中間解析

河野浩二, Yong Wei-Peng, Shabbir Asim, Ling Amy Tay Yuh, Phua Janelle Niam Sin, So Jimmy

日本外科学会定期学術集会抄録集 115回 OP-193-1 2015.4

Regenerative medicine for oesophageal reconstruction after cancer treatment.

Chian KS, Leong MF, Kono K

The Lancet. Oncology 16 ( 2 ) e84 - 92 2015.2（ ISSN:1470-2045 ）

eIF2α-Independent Inhibition of TNF-α-Triggered NF-κB Activation by Salubrinal

Nakajima Shotaro, Chi Yuan, Gao Kun, Kono Koji, Yao Jian

Ｂｉｏｌｏｇｉｃａｌ　＆　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　Ｂｕｌｌｅｔｉｎ 38 ( 9 ) 1368 - 1374 2015（ ISSN:0918-6158 ）

ANTI-TUMOR IMMUNE RESPONSES INDUCED BY RADIOTHERAPY: A REVIEW

YOSHIMOTO YUYA, KONO KOJI, SUZUKI YOSHIYUKI

FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 61 ( 1 ) 13 - 22 2015（ ISSN:0016-2590 ）

マイトジェン活性化蛋白質キナーゼ経路の阻害は、インターフェロンγ治療とは異なりPD-L1発現を亢進させることなくヒト白血球抗原クラスIの発現亢進を誘導する(Inhibition of mitogen-activated protein kinase pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment)

Mimura Kousaku, Kua Ley-Fang, Shiraishi Kensuke, Lim Kee Siang, Shabbir Asim, Komachi Mayumi, Suzuki Yoshiyuki, Nakano Takashi, Yong Wei-Peng, So Jimmy, Kono Koji

Cancer Science 105 ( 10 ) 1236 - 1244 2014.10（ ISSN:1347-9032 ）

Lapatinibは抗増殖機能とtrastuzumab介在性の抗体依存性細胞傷害性の増強を介して胃癌に作用する(Lapatinib acts on gastric cancer through both antiproliferative function and augmentation of trastuzumab-mediated antibody-dependent cellular cytotoxicity)

Shiraishi Kensuke, Mimura Kousaku, Izawa Shinichiro, Inoue Ayako, Shiba Shugo, Maruyama Takanori, Watanabe Mitsuaki, Kawaguchi Yoshihiko, Inoue Masayuki, Fujii Hideki, Kono Koji

Gastric Cancer 16 ( 4 ) 571 - 580 2013.10（ ISSN:1436-3291 ）

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