Papers - SAITO Motonobu
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Evaluation of NTRK Fusions Detection Method in Esophageal Squamous Cell Carcinoma and Gastric Adenocarcinoma.
Tomoyuki Momma, Motonobu Saito, Shotaro Nakajima, Katsuharu Saito, Erika Machida, Ken Miyabe,Yusuke Sato, Hiroyuki Hanayama, Hirokazu Okayama, Zenichiro Saze, Kosaku Mimura, Naoto Tsuchiya, Akiteru Goto, Kouya Shiraishi, Koji Kono
International journal of molecular sciences 27 ( 1 ) 336 - 336 2025.12
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Surgical Resection with Posterior Rectus Sheath Preservation and Mesh Reconstruction without Pursuing Wide Negative Margins for an Abdominal Wall Desmoid in Familial Adenomatous Polyposis: A Case Report.
Makoto Hasegawa, Tomoyuki Momma, Erina Suzuki, Yuko Hashimoto, Hiroki Yago, Misato Ito, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Hirokazu Okayama, Motonobu Saito, Wataru Sakamoto, Koji Kono
Surgical Case Reports 11 ( 1 ) 25 - 0584 2025.12（ ISSN:2198-7793 ）
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Primary Extragastrointestinal Stromal Tumor of the Dorsolateral Anorectum Resected via a Posterior Approach: A Case Report.
Makoto Hasegawa, Wataru Sakamoto, Norshalena Shakespear, Hiroki Yago, Takahiro Sato, Misato Ito, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Hirokazu Okayama, Motonobu Saito, Tomoyuki Momma, Koji Kono
Surgical Case Reports 11 ( 1 ) 25 - 0548 2025.12（ ISSN:2198-7793 ）
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Germline variants of the POLH and RAD51 genes are candidate variants associated with risk of hormone receptor-negative young-onset breast cancer.
Shu Yazaki, Rui Kitadai, Yukihide Momozawa, Teruhiko Yoshida, Takashi Yamanaka, Sho Shiino, Chisako Yamauchi, Kenichi Harano, Motonobu Saito, Yosuke Hirotsu, Hisaki Aiba, Ryuji Hamamoto, Chikako Shimizu, Akihiko Shimomura, Tatsunori Shimoi, Kazuki Sudo, Masayuki Yoshida, Kuniko Sunami, Yuichi Shiraishi, Aya Kuchiba, Megumi Hori, Kota Katanoda, Sadaaki Takata, Ayumi Ogawa, Masahiro Torasawa, Akifumi Mochizuki, Yoko Shimada, Kengo Hiranuma, Erisa Fujii, Makoto Hirata, Yuji Yamashita, Takahiro Kogawa, Takeshi Murata, Saori Fujiwara, Yohei Miyagi, Hiroshi Nakagomi, Kazunoshin Tachibana, Koichi Matsuda, Yoshinori Murakami, Katsushi Tokunaga, Yosuke Kawai, NCBN Controls WGS Consortium, Biobank Japan Project, Masao Omata, Tohru Ohtake, Akihiko Suto, Tatsuya Onishi, Yoichi Naito, Toshinari Yamashita, Kan Yonemori, Takashi Kohno & Kouya Shiraishi
NPJ Breast Cancer 11 ( 1 ) 133 - 133 2025.11（ ISSN:2374-4677 ）
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KRAS G12A Identifies a High-Risk Subset in Resected Stage II-III Colorectal Cancer.
Tomoyuki Momma, Hirokazu Okayama, Sohei Hayashishita, Daiki Yamaguchi, Ayumi Fujii, Masanori Katagata, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Zenichiro Saze, Shotaro Nakajima, Kosaku Mimura, Motonobu Saito, Wataru Sakamoto, Koji Kono
Cancers 17 ( 22 ) 3599 - 3599 2025.11（ ISSN:2072-6694 ）
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Extracellular vesicles of cancer cells induce FOXP3+ fibroblasts and facilitate tumor invasion via the Wnt3-β-catenin pathway.
Tomoaki Kimura, Kurara Takagane, Go Itoh, Sei Kuriyama, Kenji Meguro, Souichi Koyota, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Shuichi Tsukamoto, Naozane Nomura, Masafumi Horie, Motonobu Saito, Akiteru Goto, Masakazu Yashiro, Junichi Arita, Masamitsu Tanaka
Oncogene 44 ( 43 ) 4101 - 4113 2025.11
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Genomic Profiles of Pathogenic and Moderate-Penetrance Germline Variants Associated With Risk of Early-Onset Lung Adenocarcinoma.
Cho H, Shiraishi K, Sunami K, Momozawa Y, Yoshida T, Matsumoto S, Matsuda K, Saito M, Goto A, Honda T, Mochizuki A, Torasawa M, Daigo Y, Shimizu K, Kunitoh H, Yoshida Y, Hirata M, Shimada Y, Ueki M, Ono H, Gotoh M, Shimoda Igawa Y, Tateishi A, Yamaguchi Y, Inaba Higashiyama R, Machida E, Iwasaki M, Kawai Y, Yasuda H, Hamamoto J, Imoto I, Matsushita H, Takata S, Aoi T, Kaneko S, Kuchiba A, Shimomura A, Fukami M, Hattori K, Ozaki K, Asano Y; NCBN Controls WGS Consortium; Biobank Japan Project; Takano A, Kobayashi M, Miyagi Y, Tanaka K, Suzuki H, Yamaura T, Yoshida T, Goto Y, Horinouchi H, Miyazaki Y, Ito H, Nagashima T, Ohtaki Y, Imai K, Minamiya Y, Okubo K, Inazawa J, Shiraishi Y, Tokunaga K, Kamatani Y, Yatabe Y, Goto K, Tsuboi M, Watanabe SI, Ohe Y, Murakami Y, Matsuo K, Hamamoto R, Kohno T
J Thorac Oncol 20 ( 11 ) 1626 - 1638 2025.11
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Extracellular vesicles of cancer cells induce FOXP3+ fibroblasts and facilitate tumor invasion via the Wnt3-β-catenin pathway.
Kimura T, Takagane K, Itoh G, Kuriyama S, Meguro K, Koyota S, Yamamoto M, Tsukamoto T, Nomura S, Tsukamoto S, Nomura N, Horie M, Saito M, Goto A, Yashiro M, Arita J, Tanaka M
Oncogene 44 ( 43 ) 4101 - 4113 2025.11（ ISSN:0950-9232 ）
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Genomic Profiles of Pathogenic and Moderate-Penetrance Germline Variants Associated With Risk of Early-Onset Lung Adenocarcinoma.
Cho H, Shiraishi K, Sunami K, Momozawa Y, Yoshida T, Matsumoto S, Matsuda K, Saito M, Goto A, Honda T, Mochizuki A, Torasawa M, Daigo Y, Shimizu K, Kunitoh H, Yoshida Y, Hirata M, Shimada Y, Ueki M, Ono H, Gotoh M, Shimoda Igawa Y, Tateishi A, Yamaguchi Y, Inaba Higashiyama R, Machida E, Iwasaki M, Kawai Y, Yasuda H, Hamamoto J, Imoto I, Matsushita H, Takata S, Aoi T, Kaneko S, Kuchiba A, Shimomura A, Fukami M, Hattori K, Ozaki K, Asano Y, NCBN Controls WGS Consortium, Biobank Japan Project, Takano A, Kobayashi M, Miyagi Y, Tanaka K, Suzuki H, Yamaura T, Yoshida T, Goto Y, Horinouchi H, Miyazaki Y, Ito H, Nagashima T, Ohtaki Y, Imai K, Minamiya Y, Okubo K, Inazawa J, Shiraishi Y, Tokunaga K, Kamatani Y, Yatabe Y, Goto K, Tsuboi M, Watanabe SI, Ohe Y, Murakami Y, Matsuo K, Hamamoto R, Kohno T
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20 ( 11 ) 1626 - 1638 2025.11（ ISSN:1556-0864 ）
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Stratifying lung adenocarcinoma risk with multi-ancestry polygenic risk scores in East Asian never-smokers.
Blechter B, Wang X, Dai J, Karsonaki C, Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Hung RJ, Chen K, Shu XO, Kim YT, Choudhury PP, Williams J, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Li S, Zhang T, Breeze C, Wang Z, Bassig BA, Kim JH, Albanes D, Wong Sm JY, Shin MH, Chung LP, Yang Y, Zheng H, Dai H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Ho JCM, Daigo Y, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood HD, Kunitoh H, Watanabe SI, Miyagi Y, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Machiela MJ, Kim YH, Oh IJ, Lee VHF, Chang GC, Chen KY, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Gao YT, Liu J, Schwartz AG, Houlston R, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold SM, Brennan P, McKay J, Field JK, Davies MPA, Shete SS, Le Marchand L, Liu G, Andrew AS, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Cox A, Taylor F, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Jeon HS, Jiang SS, Chen Ch, Hsiao CF, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Kang CH, Wang WC, Xu J, Guan P, Tan W, Yu CJ, Yang G, Sihoe ADL, Choi YY, Park IK, Hung HH, Vermeulen RCH, Cheng I, Wu J, Tsai FY, Chan JKC, Li J, Lin HC, Liu J, Song B, Sawada N, Yamaji T, Wyatt K, Ma H, Zhu M, Wang Y, Qi T, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Wu G, Chen CY, Chen ScD CJ, Yang PC, Stevens VL, Fraumeni Jr JF, Lin K, Walters RG, Chen Z, Chatterjee N, Gorlova OY, Amos CI, Shen H, Hsiung CA, SJ Chanock, Rothman N, Kohno T, Lan Q, Zhang H
J Natl Cancer Inst 2025.10
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Stratifying lung adenocarcinoma risk with multi-ancestry polygenic risk scores in East Asian never-smokers.
Blechter B, Wang X, Dai J, Karsonaki C, Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Hung RJ, Chen K, Shu XO, Kim YT, Choudhury PP, Williams J, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Li S, Zhang T, Breeze C, Wang Z, Bassig BA, Kim JH, Albanes D, Wong Sm JY, Shin MH, Chung LP, Yang Y, Zheng H, Dai H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Ho JCM, Daigo Y, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood HD, Kunitoh H, Watanabe SI, Miyagi Y, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Machiela MJ, Kim YH, Oh IJ, Lee VHF, Chang GC, Chen KY, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Gao YT, Liu J, Schwartz AG, Houlston R, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold SM, Brennan P, McKay J, Field JK, Davies MPA, Shete SS, Le Marchand L, Liu G, Andrew AS, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Cox A, Taylor F, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Jeon HS, Jiang SS, Chen CH, Hsiao CF, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Kang CH, Wang WC, Xu J, Guan P, Tan W, Yu CJ, Yang G, Sihoe ADL, Choi YY, Park IK, Hung HH, Vermeulen RCH, Cheng I, Wu J, Tsai FY, Chan JKC, Li J, Lin HC, Liu J, Song B, Sawada N, Yamaji T, Wyatt K, Ma H, Zhu M, Wang Y, Qi T, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Wu G, Chen CY, ScD CC, Yang PC, Stevens VL, Fraumeni JF Jr, Lin K, Walters RG, Chen Z, Chatterjee N, Gorlova OY, Amos CI, Shen H, Hsiung CA, Chanock SJ, Rothman N, Kohno T, Lan Q, Zhang H
Journal of the National Cancer Institute 2025.10（ ISSN:0027-8874 ）
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GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression
Hiroya Suzuki, Hirokazu Okayama, Shotaro Nakajima, Katsuharu Saito, Ryo Kanoda, Yuya Maruyama, Akira Matsuishi, Takuro Matsumoto, Misato Ito, Shun Chida, Wataru Sakamoto, Motonobu Saito, Zenichiro Saze, Tomoyuki Momma, Kosaku Mimura, Koji Kono
Cancer research communications 5 ( 9 ) 1530 - 1540 2025.9
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GALNT7 Stratifies dMMR/MSI Colorectal Cancer into Distinct Molecular Subsets Associated with Prognosis and PD-L1 Expression.
Suzuki H, Okayama H, Nakajima S, Saito K, Kanoda R, Maruyama Y, Matsuishi A, Matsumoto T, Ito M, Chida S, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K
Cancer research communications 5 ( 9 ) 1530 - 1540 2025.9
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Partial resection of rectum for rectal GIST by posterior approach.
Makoto Hasegawa, Wataru Sakamoto, Hiroki Yago, Takahiro Sato, Misato Ito, Takuro Matsumoto, Daisuke Ujiie, Shun Chida, Hirokazu Okayama, Motonobu Saito, Tomoyuki Momma, Koji Kono
Langenbeck's archives of Surgery 410 ( 1 ) 258 - 258 2025.8（ ISSN:1435-2443 ）
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Stratifying Lung Adenocarcinoma Risk with Multi-ancestry Polygenic Risk Scores in East Asian Never-Smokers.
Blechter B, Wang X, Dai J, Karsonaki C, Shi J, Shiraishi K, Choi J, Matsuo K, Chen TY, Hung RJ, Chen K, Shu XO, Kim YT, Choudhury PP, Williams J, Landi MT, Lin D, Zheng W, Yin Z, Zhou B, Wang J, Seow WJ, Song L, Chang IS, Hu W, Chien LH, Cai Q, Hong YC, Kim HN, Wu YL, Wong MP, Richardson BD, Li S, Zhang T, Breeze C, Wang Z, Bassig BA, Kim JH, Albanes D, Wong JY, Shin MH, Chung LP, Yang Y, Zheng H, Dai H, Yatabe Y, Zhang XC, Kim YC, Caporaso NE, Chang J, Man Ho JC, Daigo Y, Momozawa Y, Kamatani Y, Kobayashi M, Okubo K, Honda T, Hosgood HD, Kunitoh H, Watanabe SI, Miyagi Y, Matsumoto S, Horinouchi H, Tsuboi M, Hamamoto R, Goto K, Takahashi A, Goto A, Minamiya Y, Hara M, Nishida Y, Takeuchi K, Wakai K, Matsuda K, Murakami Y, Shimizu K, Suzuki H, Saito M, Ohtaki Y, Tanaka K, Wu T, Wei F, Machiela MJ, Kim YH, Oh IJ, Fun Lee VH, Chang GC, Chen KY, Su WC, Chen YM, Seow A, Park JY, Kweon SS, Gao YT, Liu J, Schwartz AG, Houlston R, Gorlov IP, Wu X, Yang P, Lam S, Tardon A, Chen C, Bojesen SE, Johansson M, Risch A, Bickeböller H, Ji BT, Wichmann HE, Christiani DC, Rennert G, Arnold SM, Brennan P, McKay J, Field JK, Davies MPA, Shete SS, Le Marchand L, Liu G, Andrew AS, Kiemeney LA, Zienolddiny-Narui S, Grankvist K, Cox A, Taylor F, Yuan JM, Lazarus P, Schabath MB, Aldrich MC, Jeon HS, Jiang SS, Chen CH, Hsiao CF, Hu Z, Burdett L, Yeager M, Hutchinson A, Hicks B, Liu J, Berndt SI, Wu W, Wang J, Li Y, Choi JE, Park KH, Sung SW, Kang CH, Wang WC, Xu J, Guan P, Tan W, Yu CJ, Yang G, Loon Sihoe AD, Choi YY, Park IK, Hung HH, Vermeulen RCH, Cheng I, Wu J, Tsai FY, Chan JKC, Li J, Lin HC, Liu J, Song B, Sawada N, Yamaji T, Wyatt K, Ma H, Zhu M, Wang Y, Qi T, Li X, Ren Y, Chao A, Iwasaki M, Zhu J, Wu G, Chen CY, Chen CJ, Yang PC, Stevens VL, Fraumeni JF Jr, Lin K, Walters RG, Chen Z, Chatterjee N, Gorlova OY, Amos CI, Shen H, Hsiung CA, Chanock SJ, Rothman N, Kohno T, Lan Q, Zhang H
medRxiv : the preprint server for health sciences 2025.8
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Residual Tumor Resection After Anti-PD-1 Therapy: A Promising Treatment Strategy for Overcoming Immune Evasive Phenotype Induced by Anti-PD-1 Therapy in Gastric Cancer.
Matsuida H, Mimura K, Nakajima S, Saito K, Hayashishita S, Takiguchi C, Nirei A, Kikuchi T, Hanayama H, Okayama H, Saito M, Momma T, Saze Z, Kono K
Cells 14 ( 15 ) 1212 - 1212 2025.8
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Risk factors for early mortality among patients with gastrointestinal malignancy in the C-CAT database.
Rei Suzuki, Hiroshi Shimizu, Kentaro Sato, Hiroyuki Asama, Rei Ohira, Mitsuru Sugimoto, Rika Saito, Maiko Okano, Reiko Kimura-Tsuchiya, Motonobu Saito, Shigehira Saji, Tadayuki Takagi, Hiromasa Ohira
International journal of clinical oncology 30 ( 8 ) 1593 - 1601 2025.8
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Pimitespib therapy for a patient with PDGFRA D842V-mutant gastrointestinal stromal tumor.
Tatsuo Kanda, Masafumi Ishikawa, Kae Techigawara, Toshiyuki Saginoya, Koichi Hamada, Motonobu Saito, Noriyuki Uesugi, Yasushi Teranishi
Clinical journal of gastroenterology 18 ( 4 ) 595 - 600 2025.8
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Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer.
Kanoda R, Nakajima S, Okayama H, Kaneta A, Chida S, Matsumoto T, Saito K, Kikuchi T, Maruyama Y, Suzuki H, Mimura K, Saito M, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K
Scientific reports 15 ( 1 ) 19234 - 19234 2025.6
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Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer.
Kanoda R, Nakajima S, Okayama H, Kaneta A, Chida S, Matsumoto T, Saito K, Kikuchi T, Maruyama Y, Suzuki H, Mimura K, Saito M, Hanayama H, Sakamoto W, Momma T, Saze Z, Kono K
Scientific reports 15 ( 1 ) 19234 2025.6