Faculty Profiles - MOMMA Tomoyuki

Papers - MOMMA Tomoyuki

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The tumor cell-intrinsic cGAS-STING pathway is associated with the high density of CD8+ T cells after chemotherapy in esophageal squamous cell carcinoma.

Matsuishi A, Nakajima S, Kaneta A, Saito K, Fukai S, Sakuma M, Tsumuraya H, Okayama H, Saito M, Mimura K, Nirei A, Kikuchi T, Hanayama H, Saze Z, Sakamoto W, Momma T, Kono K

Esophagus : official journal of the Japan Esophageal Society 21 ( 2 ) 165 - 175 2024.4（ ISSN:1612-9059 ）

腫瘍細胞-内因性cGAS-STING経路は食道扁平上皮癌に対する化学療法後の高密度CD8+細胞と関連する(The tumor cell-intrinsic cGAS-STING pathway is associated with the high density of CD8+ T cells after chemotherapy in esophageal squamous cell carcinoma)

Matsuishi Akira, Nakajima Shotaro, Kaneta Akinao, Saito Katsuharu, Fukai Satoshi, Sakuma Mei, Tsumuraya Hideaki, Okayama Hirokazu, Saito Motonobu, Mimura Kosaku, Nirei Azuma, Kikuchi Tomohiro, Hanayama Hiroyuki, Saze Zenichiro, Sakamoto Wataru, Momma Tomoyuki, Kono Koji

Esophagus 21 ( 2 ) 165 - 175 2024.4（ ISSN:1612-9059 ）

化学療法に抵抗性を示した再発病変に対してPembrolizumabが奏効し長期生存を得たMSI-High S状結腸癌の1例

圓谷秀哲, 金田晃尚, 藤田正太郎, 林下宗平, 望月翔太朗, 鈴木博也, 滝口千晶, 松石彬, 丸山裕也, 叶多諒, 佐久間芽衣, 坂本渉, 門馬智之, 佐瀬善一郎, 河野浩二

癌と化学療法 50 ( 13 ) 1742 - 1744 2023.12

HER2陽性胃癌におけるHER2不均一性に依存したstimulator of interferon genes(STING)発現低下とCD8陽性T細胞浸潤(Down-regulation of stimulator of interferon genes(STING) expression and CD8+ T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer)

Fukai Satoshi, Nakajima Shotaro, Saito Motonobu, Saito Katsuharu, Kase Koji, Nakano Hiroshi, Sato Takahiro, Sakuma Mei, Kaneta Akinao, Okayama Hirokazu, Mimura Kosaku, Sakamoto Wataru, Saze Zenichiro, Momma Tomoyuki, Kono Koji

Gastric Cancer 26 ( 6 ) 878 - 890 2023.11（ ISSN:1436-3291 ）

Remodeling of the Tumor Microenvironment by Radiotherapy through the cGAS-STING Pathway in Esophageal Squamous Cell Carcinoma

Nakajima S., Mimura K., Kaneta A., Katagata M., Okayama H., Saito M., Saze Z., Hanayama H., Tada T., Momma T., Kono K.

Gan to Kagaku Ryoho Cancer Chemotherapy 50 ( 10 ) 1099 - 1101 2023.10（ ISSN:03850684 ）

放射線治療による腫瘍細胞内cGAS-STING経路を介した食道扁平上皮癌微小環境の変化

中嶋正太郎, 三村耕作, 金田晃尚, 片方雅紀, 岡山洋和, 齋藤元伸, 佐瀬善一郎, 花山寛之, 多田武志, 門馬智之, 河野浩二

癌と化学療法 50 ( 10 ) 1099 - 1101 2023.10

[Remodeling of the Tumor Microenvironment by Radiotherapy through the cGAS-STING Pathway in Esophageal Squamous Cell Carcinoma].

Nakajima S, Mimura K, Kaneta A, Katagata M, Okayama H, Saito M, Saze Z, Hanayama H, Tada T, Momma T, Kono K

Gan to kagaku ryoho. Cancer & chemotherapy 50 ( 10 ) 1099 - 1101 2023.10（ ISSN:0385-0684 ）

Down-regulation of stimulator of interferon genes (STING) expression and CD8(+) T-cell infiltration depending on HER2 heterogeneity in HER2-positive gastric cancer.

Fukai S, Nakajima S, Saito M, Saito K, Kase K, Nakano H, Sato T, Sakuma M, Kaneta A, Okayama H, Mimura K, Sakamoto W, Saze Z, Momma T, Kono K

Gastric cancer 26 ( 6 ) 878 - 890 2023.8

A Potential Biomarker of Dynamic Change in Peripheral CD45RA(-)CD27(+)CD127(+) Central Memory T Cells for Anti-PD-1 Therapy in Patients with Esophageal Squamous Cell Carcinoma.

Sakuma M, Mimura K, Nakajima S, Kaneta A, Kikuchi T, Nirei A, Tada T, Hanayama H, Okayama H, Sakamoto W, Saito M, Momma T, Saze Z, Kono K

Cancers 15 ( 14 ) 3641 2023.7（ ISSN:2072-6694 ）

The Impact of Tumor Cell-Intrinsic Expression of Cyclic GMP-AMP Synthase (cGAS)-Stimulator of Interferon Genes (STING) on the Infiltration of CD8(+) T Cells and Clinical Outcomes in Mismatch Repair Proficient/Microsatellite Stable Colorectal Cancer.

Nakajima S, Kaneta A, Okayama H, Saito K, Kikuchi T, Endo E, Matsumoto T, Fukai S, Sakuma M, Sato T, Mimura K, Saito M, Saze Z, Sakamoto W, Onozawa H, Momma T, Kono K

Cancers 15 ( 10 ) 2826 2023.5（ ISSN:2072-6694 ）

ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer.

Sato T, Saito M, Nakajima S, Saito K, Katagata M, Fukai S, Okayama H, Sakamoto W, Saze Z, Momma T, Mimura K, Kono K

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 26 ( 3 ) 379 - 392 2023.5（ ISSN:1436-3291 ）

HER2陰性胃癌においてARID1A欠損はAKT阻害薬の標的になりうる(ARID1A deficiency is targetable by AKT inhibitors in HER2-negative gastric cancer)

Sato Takahiro, Saito Motonobu, Nakajima Shotaro, Saito Katsuharu, Katagata Masanori, Fukai Satoshi, Okayama Hirokazu, Sakamoto Wataru, Saze Zenichiro, Momma Tomoyuki, Mimura Kosaku, Kono Koji

Gastric Cancer 26 ( 3 ) 379 - 392 2023.5（ ISSN:1436-3291 ）

Radiation-induced remodeling of the tumor-microenvironment through tumor cell-intrinsic expression of cGAS-STING in esophageal squamous cell carcinoma.

Nakajima S, Mimura K, Kaneta A, Saito K, Katagata M, Okayama H, Saito M, Saze Z, Watanabe Y, Hanayama H, Tada T, Sakamoto W, Momma T, Ohira H, Kono K

International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2023.3（ ISSN:0360-3016 ）

Radiation-Induced Remodeling of the Tumor Microenvironment Through Tumor Cell-Intrinsic Expression of cGAS-STING in Esophageal Squamous Cell Carcinoma.

Nakajima S, Mimura K, Kaneta A, Saito K, Katagata M, Okayama H, Saito M, Saze Z, Watanabe Y, Hanayama H, Tada T, Sakamoto W, Momma T, Ohira H, Kono K

International journal of radiation oncology, biology, physics 115 ( 4 ) 957 - 971 2023.3（ ISSN:0360-3016 ）

M2 tumor-associated macrophages resist to oxidative stress through heme oxygenase-1 in the colorectal cancer tumor microenvironment.

Ito M, Mimura K, Nakajima S, Okayama H, Saito K, Nakajima T, Kikuchi T, Onozawa H, Fujita S, Sakamoto W, Saito M, Momma T, Saze Z, Kono K

Cancer immunology, immunotherapy : CII 72 ( 7 ) 2233 - 2244 2023.3（ ISSN:0340-7004 ）

Systemic inflammation score as a preoperative prognostic factor for patients with pT2-T4 resectable gastric cancer: a retrospective study.

Matsumoto T, Ohki S, Kaneta A, Matsuishi A, Maruyama Y, Yamada L, Tada T, Hanayama H, Watanabe Y, Hayase S, Okayama H, Sakamoto W, Momma T, Saze Z, Kono K

BMC surgery 23 ( 1 ) 8 2023.1

TIM-3 Expression and M2 Polarization of Macrophages in the TGFβ-Activated Tumor Microenvironment in Colorectal Cancer.

Katagata M, Okayama H, Nakajima S, Saito K, Sato T, Sakuma M, Fukai S, Endo E, Sakamoto W, Saito M, Saze Z, Momma T, Mimura K, Kono K

Cancers 15 ( 20 ) 4943 2023

Clinical outcomes of laparoscopic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumor.

Hanayama Hiroyuki, Katagata Masanori, Sato Takahiro, Nakano Hiroshi, Matsumoto Takuro, Tada Takeshi, Watanabe Yohei, Hayase Suguru, Okayama Hirokazu, Momma Tomoyuki, Kato Tsunetaka, Hashimoto Minami, Nakamura Jun, Hikichi Takuto, Saze Zenichiro, Kono Koji

Fukushima Journal of Medical Science 68 ( 3 ) 169 - 174 2022.12（ ISSN:0016-2590 ）

Myeloid-derived suppressor cells: Cancer, autoimmune diseases, and more.

Shibata M, Nanno K, Yoshimori D, Nakajima T, Takada M, Yazawa T, Mimura K, Inoue N, Watanabe T, Tachibana K, Muto S, Momma T, Suzuki Y, Kono K, Endo S, Takenoshita S

Oncotarget 13 1273 - 1285 2022.11

Short-term outcomes of neoadjuvant chemotherapy with capecitabine plus oxaliplatin for patients with locally advanced rectal cancer followed by total or tumor-specific mesorectal excision with or without lateral pelvic lymph node dissection.

Sakamoto W, Kanke Y, Onozawa H, Okayama H, Endo H, Fujita S, Saito M, Saze Z, Momma T, Kono K

Fukushima journal of medical science 68 ( 2 ) 89 - 95 2022.8（ ISSN:0016-2590 ）

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Papers - MOMMA Tomoyuki