Updated on 2021/06/25

写真a

 
HONDA Takashi
 
Organization
School of Medicine (Life Sciences and Social Medicine) Department of Forensic Medicine Postdoctoral Researcher
Title
Postdoctoral Researcher
Contact information
メールアドレス

Degree

  • 医学博士 ( 2002.3   福島県立医科大学 )

Research Interests

  • Bradykinin,c-fos, Machine hyperalgesia, Cell Death,neuropeptide, nerve injury,neuron degeneration,Demyelination,immunohistochemistry, immunoelectron microscopy

Research Areas

  • Life Science / Experimental pathology  / Experimental Pathology

  • Life Science / Clinical pharmacy  / neurophysiology

  • Life Science / Anatomy  / Gross Anatomy(include Human embryology)

  • Life Science / Physiology  / neurophysiology

Education

  • Fukushima Medical University   Faculty of Medicine

    - 1983

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    Country: Japan

Research History

  • Fukushima Medical University   School of Medicine (Life Sciences and Social Medicine) Department of Forensic Medicine   Postdoctoral Researcher

    2020.4 - Now

  • Fukushima Medical University   School of Nursing Department of Human Life Sciences   Professor

    2017.2 - 2020.3

Papers

  • Soluble protein tyrosine phosphatase receptor type Z (PTPRZ) in cerebrospinal fluid is a potential diagnostic marker for glioma

    Yamanoi Yu, Fujii Masazumi, Murakami Yuta, Nagai Kenichiro, Hoshi Kyoka, Hashimoto Yasuhiro, Takashi Honda, Saito Kiyoshi, Kitazume Shinoby

    Neuro-oncology Advances   2 ( 1 )   vdaa055   2020.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1093/noajnl/vdaa005

  • Ratio of alpha 2-macroglobulin levels in cerebrospinal fluid and serum: an expression of neuroinflammation in acute disseminated encephalonyelitis

    Suzuki Yuichi, Hashimoto Koichi, Hoshi Kyoka, Ito Hiromi, Kariya Yoshinobu, Miyazaki Kyohei, Sato Masatoki, Kawasaki, Yukihiko, Yoshida Mari, Honda Takashi, Hashimoto Yasuhiro, Hosoya Mitsuyasu

    J. Pediatric Neurology   98   61 - 67   2019

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    Language:English   Publishing type:Research paper (scientific journal)  

  • A unique glycan-isoform of transferrin in cerebrospinal fluid: a potential diagnostic marker for neurological diseases

    Kyoka Hoshi, Yuka Matsumoto, Hiromi Ito, Kiyoshi Saito, Takashi Honda, Yoshiki Yamaguchi, Yasuhiro Hashimoto

    BBA - General Subjects   1861   2473 - 2478   2017.9

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Lectin inhibits antigen-antibody reaction in a glycoform-specific manner: Application for detecting α2,6sialylated-carcinoembryonic antigen

    Hiromi Ito, Kyoka Hoshi, Fumihiko Osuka, Mitsukazu Gotoh, Takuro Saito, Hiroshi Hojo, Rei Suzuki, Hiromasa Ohira, Takashi Honda and Yasuhiro Hashinoto

    Proteomics   16   3081 - 3084   2016.8

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    Language:English   Publishing type:Research paper (other academic)  

  • Increased cerebrospinal fluid osteopontin levels and its involvement in macrophage infiltration in neuromyelitis optica.

    Yoshinobu Kariya, Yukiko Kariya, Toshie Saito, Shuhei Nishiyama, Takashi Honda, Keiko Tanaka, Mari Yoshida, Kazuo Fujihara, Yasuhiro Hashimoto

    BBA Clinical   3   126 - 134   2015

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    Language:English   Publishing type:Research paper (other academic)  

  • In situ visualization of a glycoform of transferrin: location of α2,6-sialylated transferrin in the liver.

    Yuka Matsumoto, Toshie Saito, Kyoka Hoshi, Hiromi Ito, Yushinobu Kariya, Masamichi Nagae, Yoshiki Yamaguchi, Yoshiaki Hagiwara, Noriaki Kinoshita, Ikuo Wada, Kiyoshi Saito, Takashi Honda, Yasuhiro Hashimoto

    J. Biochemistory   1 - 7   2015

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    Language:English   Publishing type:Research paper (other academic)  

  • A unique N-glycan on human transferrin in CSF: a possible biomarker for iNPH

    FUTAKAWA, Satoshi*; NARA, Kiyomitsu*; MIYAJIMA, Masakazu; KUNO, Atsushi; ITO, Hiromi*; KAJI, Hiroyuki; SHIROTANI, Keiro*; HONDA, Takashi*; TOHYAMA, Yuriko*; HOSHI, Kyoka*; HANZAWA, Yusuke*; KITAZUME, Shinobu; IMAMAKI, Rie; FURUKAWA, Katsutoshi; TASAKI, Kazuhiro*; ARAI, Hiroyuki; YUASA, Tatsuhiko; ABE, Masafumi*; ARAI, Hajime; NARUMATSU, Hisashi; HASHIMOTO, Yasuhiro*

    Neurobiology of Aging   33   1807 - 1815   2012

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    Language:English   Publishing type:Research paper (other academic)  

  • Brain endothelial cells produce amyroidβ from amyroid precursor protein 770 and preferentially secrete the 0-glycosylated form

    Shinobu Kitazume, Yuriko Tachida, Masaki Kato, Yoshiki Yamaguchi, Takashi Honda, Yasuhiro Hashimoto, Yoshinao Wada, Takashi Saito, Nobuhisa Iwata, Takaomi Saido, Naoyuki Taniguchi

    J. Biological Chemistory   285 ( 51 )   40097 - 40103   2010.11

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    Language:English   Publishing type:Research paper (other academic)  

  • The inner ear is involved in the aggravation of nociceptive behavior induced by lowering barometric pressure of nerve injured rats

    Funakubo M., Sato J., Honda T. and Mizumura K.

    European Journal of Pain [Epub ahead of print]   14   32 - 39   2010.2( ISSN:1090-3801 (Print)

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  • Influences of Autonomic Nervous System on Atrial Arrythmogenic Substrates and the Incidence of Atrial Fibrillation in Diabetic Heart.

    Hideki Otake, Hitoshi Suzuki, Takashi Honda, Yukio Maruyama

    International Heart Journal   50 ( 5 )   627 - 641   2009.9

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    Language:English   Publishing type:Research paper (other academic)  

  • Histological study on side effects and tumor targeting of a block copolymer nicelle on rats

    Takanori Kawaguchi, Takashi Honda, Masamichi Nishihara, Tatsuhiro Yamamoto, Masayuki Yokoyama

    Journal of Controlled Release   136 ( 3 )   240 - 246   2009.6

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  • Design of Folate-Linked Liposomal Doxiorubicin to its Antitumor Effect in Mice.

    Atsushi Yamada, Yukimi Taniguchi, Kumi Kawano, Takashi Honda, Yoshiyuki Hattori, Yoshie Maitani

    Clini. Cancer Res.   14 ( 24 )   8161 - 8168   2008.12

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    Language:English   Publishing type:Research paper (other academic)  

  • Nerve Growth Factor in Saliva Stimulated by Mastication

    Kiyomi Komatsu, Hiroshi Hasegawa, Takashi Honda, Atsuko Yabashi and Tateharu Kawasaki

    Oral Science International   5 ( 2 )   78 - 84   2008.11

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  • Interleukin-1β Upregulates TACE to Enhance α-Cleavage of APP in Neurons: Resulting Decrease in Aβ Production.

    Yuriko Tachida, Kazuhiro Nakagawa, Takashi Saito, Takaomi C. Saido, Takashi Honda, Yuko Saito, Shigeo Murayama, Tamao Endo, Gaku Sakaguchi, Akira Kato, Shinobu Kitazume, Yasuhiro Hashimoto

    J. Neurochemistry   104 ( 5 )   1387 - 1393   2008

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    Language:English   Publishing type:Research paper (other academic)  

  • Rab-small GTPases are involved in statin-induced vacuolation in rat skeletal myofibers

    Kazuho Sakamoto, Takashi Honda, Sachihiko Yokoya, Satoshi Waguri, and Junko Kimura

    FASEB J   21   1 - 9   2007

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  • High-frequency monopolar electrical stimulation of the rat cerebral cortex

    Masahiro Oinuma, Kyouichi Suzuki, Takashi Honda, Masato Matsumoto, Tatsuya Sasaki, Namio Kodama

    Neurosurgery   60   189 - 197   2007

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  • Increase of 200-kDa neurofilament-immunoreactive afferents in the substantia gelatinosa in allodynic rats induced by compression of the dorsal root ganglion.

    Watanabe K., Konno S., Sekiguchi M., Sasaki N., Honda T. and Kikuchi S.

    Spine   3212   1265 - 1271   2007

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    Language:English   Publishing type:Research paper (other academic)  

  • Cisplatin-Incorporating Polymeric Micelles (Nanoplatin) Can Reduce Nephrotoxicity and Neurotoxicity of Cisplatin in rats

    Hiroshi Uchino1, Takahito Negishi1, Tatsuyuki Hayashi, Takashi Honda, Nobuhiro Nishiyama, Kazunori Kataoka, Seiji Naito, and Yasuhiro Matsumura

    British journal of cancer   93   678 - 687   2005

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  • A hind limb tourniquet induces interleukin-6 expression in a rat dorsal root ganglion

    Sumiko Abe, Ikubumi Mizusawa, Miwako Suto, Naho Kato, Atsuko Yabashi, Takashi Honda and Kouichi Hiraiwa

    Neuroreport   16 ( 17 )   1889 - 1892   2005

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  • GD3 synthase gene knockout mice exhibit thermal hyperalgesia and mechanical allodynia but decreased responce to formalin-induced prolonged noxious stimulation

    Yoshihiro Handa, Noriyuki Ozaki, Takashi Honda, Koichi Furukawa, Yasushi Tomita, Masahiro Inoue, Keiko Furukawa, Masahiko Okada and Yasuo Sugiura

    Pain   117   271 - 279   2005

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    Language:English   Publishing type:Research paper (other academic)  

  • Application of the backscattered electron imaging for observation of biological specimen using the resin-embedded and de-embedded samples

    Takashi Honda and Masao Honda

    Fukushima journal of medical science   48   1 - 13   2002

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  • Comparison of sensory and sympathetic innervation of the dura mater and posterior longitudinal ligament in the cervical spine after removal of the stellate ganglion

    J. Comparative Neurology   434   86 - 100   2001

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  • Co-localization of the glial cell-line derived neurotrophic factor (GDNF) and its functional receptor c-RET in a subpopulation of rat dorsal root ganglion neurons

    Neuroscience Letters   275   45 - 48   1999

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  • Evidence for the c-ret protooncogene product (C-Ret) expression in the spinal tanycytes of adult rat

    J. of Chemical Neuroanatomy   17 ( 3 )   163 - 168   1999

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  • Noxious stimuli evoke Fos expression even in the spinal dorsal horn of the chemically analgesic rats.

    Society for Neuroscience, Abstracts   20   1410   1995

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  • Fos expression induced by noxious stimuli in the spinal dorsal horn of the chemically analgesic rats

    4th IBRO World Congress of Neuroscience. Abstract   304   1995

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  • Defferent reactions of secondary afferent neurons with or without injury of primary afferent nerves ; An expression in the spinal dorsal horn of the systemic capsaicin-treated rats

    Acta Anatomica Nipponica   70   57   1995

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  • Synaptic organization and ultrastructural features of the substance P-receptor-like immunoreactive neurons in the nucleus untermediolateralis of rats"

    Neuroscience Letters   197   117 - 120   1995

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  • Neuronal damages of the primary afferent neurons evoke Fos expression even in the spinal dorsal horn of the capsaicin-induced analgesic rats

    Takashi Honda, Satoko Oda, Noriyuki Ozaki, Yoshikazu Tonosaki, Keiji Nishiyama, Yasuo Sugiura

    Pain Research   10   61 - 70   1995

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  • An ultrastructural study of cholinergic and non-chollinergic neurons in the laterodorsal and pedunculopontine tegmental nuclei in rat

    Neuroscience   69 ( 3 )   837 - 853   1995

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  • Serotonergic synaptic input to cholinergic neurons in the mesopontine tegmentum in rat

    Takashi Honda, Kazue Semba

    Brain Research   647   299 - 306   1994

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  • Quantitative analysis of central terminal projections of visceral and somatic unmyelinated (C) primary afferent fibers in the guinea pig

    Journal of Comparative Neurology   332   315 - 325   1993

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  • Ultrastructural evidence for serotonergic input to cholinergic neurons in the laterodorsal tegmental nucleus in the rat

    Society for Neurosci. Abstracts.   18   859   1992

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  • Glycosylation controls cooperative PECAM-VEGFR2-β3 integrin functions at the endothelial surface for tumor angiogenesis

    Rie Imamaki, Kazuko Ogawa, Yusuke Komi, Soichi Kojima, Norihiro Kotani, Koichi Honke, Takashi Honda, Naoyuki Taniguchi, Shinobu Kitazume

    Oncogene   37   4287 - 4299   2018

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  • Rapid increase of “brain-type” transferrin in cerebrospinal fluid after shunt surgery for idiopathic normal pressure hydrocephalus: a prognosis marker for cognitive recovery.

    Murakami Yuta, Matsumoto Yuka, Hoshi Kyoka, Ito Hiromi, Fuwa Takashi J., Yamaguchi Yoshiki, Nakajima Madoka, Miyajima Masakazu, Arai Hajime, Nollet Kenneth, Kato Naho, Nishikata Rie, Kuroda Naohito, Honda Takashi, Sakuma Jun, Saito Kiyoshi, Hashimoto Yasuhiro

    Journal of Biochemistry   164 ( 3 )   206 - 213   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1093/jb/mvy043

  • Lectin-based assay for glycoform-specific detection of alpha2,6sialylated transferrin and carcinoembryonic antigen in tissue and body fluid.

    Ito Hiromi, Hoshi Kyoka, Honda Takashi, Hashimoto Yasuhiro

    Molecules   23   1314 - 1314   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3390/molecules23061314

  • A unique glycan-isoform of transferrin in cerebrospinal fluid: A potential diagnostic marker for neurological diseases.

    Hoshi K, Matsumoto Y, Ito H, Saito K, Honda T, Yamaguchi Y, Hashimoto Y

    Biochimica et biophysica acta   1861 ( 10 )   2473 - 2478   2017.10( ISSN:0006-3002

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.bbagen.2017.07.005

    PubMed

  • A unique glycan-isoform of transferrin in cerebrospinal fluid: A potential diagnostic marker for neurological diseases

    Kyoka Hoshi, Yuka Matsumoto, Hiromi Ito, Kiyoshi Saito, Takashi Honda, Yoshiki Yamaguchi, Yasuhiro Hashimoto

    BBA-General Subjects   1861   2473 - 2478   2017

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.bbagen. 2017.07.005

  • The assessment of oral hygiene with the ATP detection test (Part 2) : A comparative study of tooth brushing and gargling-related variation using the salivary ATP

    Miura Asako, Honda Takashi, Murakami Momoe, Asakawa Hiromi, Saito Kazumi, Watanabe Yuka, Horimoto Miki, Sato Mayu, Watanabe Yuki, Yashima Yasuko, Minegishi Chiharu

    Bulletin of Fukushima School of Nursing   18   1 - 9   2016.3( ISSN:13446975

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Atrophy of submandibular gland by the duct ligation and a blockade of SP receptor in rats

    Hishida S., Ozaki N., Honda T., Shigetomi T., Ueda M., Hibi H., Sugiura Y.

    Nagoya Journal of Medical Science   78 ( 2 )   215 - 227   2016.1( ISSN:00277622

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  • Lectin inhibits antigen-antibody reactioon in a glycoform-specific manner: Application for detecting alpha2,6sialylated-carcinoembryonic antigen

    Ito Hiromi*, Hoshi Kyoka*, Osuka Fumihiko*, Gotoh Mitsukazu*, Saito Takuro*, Hojo Hiroshi*, Suzuki Rei*, Ohira Hiromasa*, Honda Takashi*, Hashimoto Yasuhiro*

    PROTEOMICS   16 ( 24 )   3081 - 3084   2016

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  • 脳型トランスフェリンの基礎と臨床:疾患マーカーとしての糖鎖修飾

    星 京香、橋本康弘、本多たかし、宮嶋雅一、新井一、荒井啓行、古川敏勝

    Annual Review神経2015   2015

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    Language:Japanese   Publishing type:Research paper (other academic)  

  • The Assessment of Oral Hygiene with the ATP Detection Test: A Comparative Study of Tooth Brushing-Related Diurnal Variation Using the Salivary ATP Swab Test

    Miura Asako, Honda Takashi

    Bulletin of Fukushima School of Nursing   16   27 - 36   2014.3( ISSN:13446975

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  • In situ visualization of a glycoform of transferrin: Localization of α2,6-sialylated transferrin in the liver

    Yuka Matsumoto*, Toshie Saito*, Kyoka Hoshi*, Hiromi Ito*, Yoshinobu Kariya*, Masamichi Nagae, Yoshiki Yamaguchi, Yoshiaki Hagiwara, Noriaki Kinoshita, Ikuo Wada*, Kiyoshi Saito*, Takashi Honda* and Yasuhiro Hashimoto*

    Journal of Biochemistry   157 ( 4 )   211 - 6   2014

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    Language:English   Publishing type:Research paper (other academic)  

    DOI : 10.1093/jb/mvu071.

  • 髄液中トランスフェリンと特発性正常圧水頭症

    橋本康弘、本多たかし、古川勝敏、荒井啓行、宮嶋雅一、新井一

    Clinical Neuroscience   31 ( 5 )   618 - 619   2013.5

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    Language:Japanese   Publishing type:Research paper (other academic)  

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Books

  • Methods of Molecular Biology: Lectin Purification and Analysis

    Hirabayashi Jun(Glycoform-specific visualization in immunohistochemistry by "Lectin inhibition")

    Springer Nature Japan  2020  ( ISBN:978-1-0716-0429-8

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    Responsible for pages:10   Language:English   Book type:Scholarly book

    Authors name of the chapter and paper which it took charge of:Ito Hiromi, Hoshi Kyoka, Hashimoto Yasuhiro, Honda Takashi   Publication place:Tokyo  

  • Glycoscience: Biology and Medicine

    Taniguchi Naoyuki, Endo Tamao, Hart Gerald, Seeberger Peter, Wong Chi-Huey(A Glycan Marker for Idiopathic Normal Pressure Hydrocephalus)

    Springere Verlag Tokyo  2014 

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    Responsible for pages:7   Language:English   Book type:Scholarly book

    Authors name of the chapter and paper which it took charge of:Hoshi Kyoka, Matsumoto Yuka, Saito Toshie, Ito Hiromi, Kariya Yoshinobu, Yamaguchi Yoshiki, Furukawa Katsutoshi, Arai Hiroyuki, Miyajima Masakazu, Arai Hajime, Nrimatsu Hisashi, Saito Kiyoshi, Honda Takashi, Hashimoto Yasuhiro   Publication place:Tokyo  

  • Aggressive Breast Cancer

    Regina H. DeFrina(Relationship Between Carbohydrate Expression Profiles of Cancer Cells and Prognosis of Breast Cancer Patients.)

    NOVA Science Publishers, Inc.  2010.7  ( ISBN:978-1-60876-881-3

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    Responsible for pages:231-235   Language:English  

    Authors name of the chapter and paper which it took charge of:Takanori Kawaguchi, Masahiko Kanno, Shuji Asahi, Takashi Honda   Publication place:New York  

  • Aggressive Breast Cancer

    Regina H. DeFrina(Lymphatic Spreading Propensity and Aberrant MUC1 Bearing TN/TN-like Carbohydrate opf Aggressive Breast Cancer Cells.)

    NOVA Science Publishers, Inc  2010.7  ( ISBN:978-1-60876-881-3

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    Responsible for pages:199-228   Language:English  

    Authors name of the chapter and paper which it took charge of:Takanori Kawaguchi, Masahiko Knnno, Hiroshi Takazawa, Shunsuke Imai, Jyunji Morimoto, Satomi, Haga, Takashi Honda   Publication place:New York  

  • Cancer Metastasis Research

    Akira Watanabe(Demonstration and Partial Identification of Aberrant Muc1 Bearing Tn Antigen in Rat Ascites Hepatoma AH109A Cells with Strong Lymph Node Metastasis Propensity)

    Nova Science Publishers  2008 

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    Responsible for pages:147-163   Language:English  

    Authors name of the chapter and paper which it took charge of:Takanori Kawaguchi, Shunsuke Imai, Satomi Haga, Jyunji Morimoto and Takashi Honda   Publication place:  

  • 神経科学の基礎と臨床XI 脳室およびその周囲器官

    板倉徹(脳室の解剖学-その形態の示すもの)

    ブレーン出版  2003.1 

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    Responsible for pages:1-11   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本多たかし   Publication place:  

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Presentations

  • 髄液代謝異常症とトランスフェリン糖鎖異性体

    第37回日本糖質学会年会  

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    Event date: 2018.8

  • 髄液産生マーカーとしてのトランスフェリン

    京都髄液フォーラム2018  

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    Event date: 2018.8

  • 脈絡叢組織に対するレクチン染色を用いた形態学的検討

    第19回日本正常圧水頭症学会  

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    Event date: 2018.2

  • 特発性正常圧水頭症における髄液トランスフェリンの定量及び形態学的検討

    第10回日本水頭症脳脊髄液学会  

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    Event date: 2017.11

  • レクチン阻害法による糖鎖アイソフォームの測定

    東北糖鎖研究会・東京糖鎖研究会合同シンポジウム(第11回東北糖鎖研究会・GlycoTOKYO 2017)  

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    Event date: 2017.11

  • ホルマリン固定大腸癌由来のα2,6シアリル化癌胎児性抗原の検出

    第89回日本生化学会大会  

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    Event date: 2016.9

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