株式会社セラバリューズ 研究員

2009.1 - 2011.5

北海道大学環境ナノ・バイオ工学研究センター 学術研究員

2008.4 - 2009.1

北海道大学大学院工学研究科 21世紀COEプログラム 博士研究員

2004.4 - 2008.4

Cutting Edge: A Critical Role of Lesional T Follicular Helper Cells in the Pathogenesis of IgG4-Related Disease.

Kamekura R, Takano K, Yamamoto M, Kawata K, Shigehara K, Jitsukawa S, Nagaya T, Ito F, Sato A, Ogasawara N, Tsubomatsu C, Takahashi H, Nakase H, Himi T, Ichimiya S

Journal of immunology (Baltimore, Md. : 1950)   199 ( 8 )   2624 - 2629   2017.10（ ISSN:0022-1767 ）

「自然免疫とアレルギー疾患　最新の病態」に寄せる　腸内細菌による濾胞ヘルパーT細胞制御の可能性と免疫アレルギー病態

川田 耕司, 一宮 慎吾

アレルギーの臨床   37 ( 3 )   252 - 255   2017.3（ ISSN:0285-6379 ）

Role of Lesional BCL6hiPD-1hi T Follicular Helper Cells As a Cardinal B-Cell Helper to Produce IgG4 in IgG4-Related Disease

Ryuta Kamekura, Kenichi Takano, Motohisa Yamamoto, Koji Kawata, Sumito Jitsukawa, Tomonori Nagaya, Fumie Ito, Chieko Tsubomatsu, Hiroki Takahashi, Tetsuo Himi, Shingo Ichimiya

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   139 ( 2 )   AB13 - AB13   2017.2（ ISSN:0091-6749 ）

Functional RNAs control T follicular helper cells.

Ichimiya S, Kamekura R, Kawata K, Kamei M, Himi T

Journal of human genetics   62 ( 1 )   81 - 86   2017.1（ ISSN:1434-5161 ）

Lipid mediators foster the differentiation of T follicular helper cells.

Nagaya T, Kawata K, Kamekura R, Jitsukawa S, Kubo T, Kamei M, Ogasawara N, Takano KI, Himi T, Ichimiya S

Immunology letters   181   51 - 57   2017.1（ ISSN:0165-2478 ）

Bob1 limits cellular frequency of T-follicular helper cells.

Yamashita K, Kawata K, Matsumiya H, Kamekura R, Jitsukawa S, Nagaya T, Ogasawara N, Takano K, Kubo T, Kimura S, Shigehara K, Himi T, Ichimiya S

European journal of immunology   46 ( 6 )   1361 - 1370   2016.6（ ISSN:0014-2980 ）

Role of Circulating ICOS plus Follicular Helper T Cells in the Pathogenesis of Birch Pollen Allergy

Ryuta Kamekura, Koji Kawata, Sumito Jitsukawa, Tomonori Nagaya, Keiji Yamashita, Fumie Ito, Kenichi Takano, Katsunori Shigehara, Tetsuo Himi, Shingo Ichimiya

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY   137 ( 2 )   AB393 - AB393   2016.2（ ISSN:0091-6749 ）

Novel Mechanisms of Compromised Lymphatic Endothelial Cell Homeostasis in Obesity: The Role of Leptin in Lymphatic Endothelial Cell Tube Formation and Proliferation.

Sato A, Kamekura R, Kawata K, Kawada M, Jitsukawa S, Yamashita K, Sato N, Himi T, Ichimiya S

PloS one   11 ( 7 )   e0158408   2016

Oral administration of the beta-glucan produced by Aureobasidium pullulans ameliorates development of atherosclerosis in apolipoprotein E deficient mice

Shiho Aoki, Atsushi Iwai, Koji Kawata, Daisuke Muramatsu, Hirofumi Uchiyama, Mitsuyasu Okabe, Masahiro Ikesue, Naoyoshi Maeda, Toshimitsu Uede

JOURNAL OF FUNCTIONAL FOODS   18   22 - 27   2015.10（ ISSN:1756-4646 ）

Oral administration of the Aureobasidium pullulans-derived β-glucan effectively prevents the development of high fat diet-induced fatty liver in mice.

Aoki S, Iwai A, Kawata K, Muramatsu D, Uchiyama H, Okabe M, Ikesue M, Maeda N, Uede T

Scientific reports   5   10457   2015.7

Alteration of circulating type 2 follicular helper T cells and regulatory B cells underlies the comorbid association of allergic rhinitis with bronchial asthma.

Kamekura R, Shigehara K, Miyajima S, Jitsukawa S, Kawata K, Yamashita K, Nagaya T, Kumagai A, Sato A, Matsumiya H, Ogasawara N, Seki N, Takano K, Kokai Y, Takahashi H, Himi T, Ichimiya S

Clinical immunology (Orlando, Fla.)   158 ( 2 )   204 - 211   2015.6（ ISSN:1521-6616 ）

Alteration of human blood type 2 follicular helper T cells and regulatory B cells underlies comorbid association of allergic rhinitis with bronchial asthma

Ryuta Kamekura, Katsunori Shigehara, Sumito Jitsukawa, Koji Kawata, Tetsuo Himi, Shingo Ichimiya

JOURNAL OF IMMUNOLOGY   194   2015.5（ ISSN:0022-1767 ）

Stimulation of macrophages with the β-glucan produced by aureobasidium pullulans promotes the secretion of tumor necrosis factor-related apoptosis inducing ligand (TRAIL).

Kawata K, Iwai A, Muramatsu D, Aoki S, Uchiyama H, Okabe M, Hayakawa S, Takaoka A, Miyazaki T

PloS one   10 ( 4 )   e0124809   2015

POU2AF1 arranges systemic distribution of follicular helper T cells

Keiji Yamashita, Yukari Mitsuhashi, Tomonori Nagaya, Sumito Jistukawa, Ryuta Kamekura, Nobuhiko Seki, Ayako Kumagai, Koji Kawata, Tetsuo Himi, Singo Ichimiya

JOURNAL OF IMMUNOLOGY   192   2014.5（ ISSN:0022-1767 ）

Stimulation with the Aureobasidium pullulans-produced β-glucan effectively induces interferon stimulated genes in macrophage-like cell lines.

Muramatsu D, Kawata K, Aoki S, Uchiyama H, Okabe M, Miyazaki T, Kida H, Iwai A

Scientific reports   4   4777   2014.4

ΔNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.

Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S

PloS one   9 ( 8 )   e105498   2014

A small scale study on the effects of oral administration of the β-glucan produced by Aureobasidium pullulans on milk quality and cytokine expressions of Holstein cows, and on bacterial flora in the intestines of Japanese black calves.

Uchiyama H, Iwai A, Asada Y, Muramatsu D, Aoki S, Kawata K, Kusano K, Nagashima K, Yasokawa D, Okabe M, Miyazaki T

BMC research notes   5   189   2012.6

RelE-mediated dormancy is enhanced at high cell density in Escherichia coli.

Tashiro Y, Kawata K, Taniuchi A, Kakinuma K, May T, Okabe S

Journal of bacteriology   194 ( 5 )   1169 - 1176   2012.3（ ISSN:0021-9193 ）

β-Glucan derived from Aureobasidium pullulans is effective for the prevention of influenza in mice.

Muramatsu D, Iwai A, Aoki S, Uchiyama H, Kawata K, Nakayama Y, Nikawa Y, Kusano K, Okabe M, Miyazaki T

PloS one   7 ( 7 )   e41399   2012

Localized expression profiles of rpoS in Escherichia coli biofilms.

Ito A, May T, Taniuchi A, Kawata K, Okabe S

Biotechnology and bioengineering   103 ( 5 )   975 - 983   2009.8（ ISSN:0006-3592 ）

In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells.

Kawata K, Osawa M, Okabe S

Environmental science & technology   43 ( 15 )   6046 - 6051   2009.8（ ISSN:0013-936X ）

Increased antibiotic resistance of Escherichia coli in mature biofilms.

Ito A, Taniuchi A, May T, Kawata K, Okabe S

Applied and environmental microbiology   75 ( 12 )   4093 - 4100   2009.6（ ISSN:0099-2240 ）

Comparison of gene expression profiles in HepG2 cells exposed to arsenic, cadmium, nickel, and three model carcinogens for investigating the mechanisms of metal carcinogenesis.

Kawata K, Shimazaki R, Okabe S

Environmental and molecular mutagenesis   50 ( 1 )   46 - 59   2009.1（ ISSN:0893-6692 ）

Significance of rpoS during maturation of Escherichia coli biofilms.

Ito A, May T, Kawata K, Okabe S

Biotechnology and bioengineering   99 ( 6 )   1462 - 1471   2008.4（ ISSN:0006-3592 ）

Classification of heavy-metal toxicity by human DNA microarray analysis.

Kawata K, Yokoo H, Shimazaki R, Okabe S

Environmental science & technology   41 ( 10 )   3769 - 3774   2007.5（ ISSN:0013-936X ）

Simple and rapid PCR method for identification of streptococcal species relevant to animal infections based on 23S rDNA sequence.

Kawata K, Anzai T, Senna K, Kikuchi N, Ezawa A, Takahashi T

FEMS microbiology letters   237 ( 1 )   57 - 64   2004.8（ ISSN:0378-1097 ）

A three-year study of enterohemorrhagic Escherichia coli O157 on a farm in Japan.

Ezawa A, Gocho F, Saitoh M, Tamura T, Kawata K, Takahashi T, Kikuchi N

The Journal of veterinary medical science   66 ( 7 )   779 - 784   2004.7（ ISSN:0916-7250 ）

High prevalence of enterohemorrhagic Escherichia coli (EHEC) O157 from cattle in selected regions of Japan.

Ezawa A, Gocho F, Kawata K, Takahashi T, Kikuchi N

The Journal of veterinary medical science   66 ( 5 )   585 - 587   2004.5（ ISSN:0916-7250 ）

rDNA sequence analyses of Streptococcus dysgalactiae subsp. equisimilis isolates from pigs.

Kawata K, Minakami T, Mori Y, Katsumi M, Kataoka Y, Ezawa A, Kikuchi N, Takahashi T

International journal of systematic and evolutionary microbiology   53 ( Pt 6 )   1941 - 1946   2003.11（ ISSN:1466-5026 ）

Functional involvement of BOB1 in the numerical regulation of follicular helper T cells.

The 44rd annual meeting of the Japanese society for immunology.  

POU2AF1 regulates the viability of follicular helper T cells.

The 43rd annual meeting of the Japanese society for immunology.