日本薬学会

日本神経精神薬理学会

日本神経化学会

予防薬理学研究所

Upregulation of Slc38a1 Gene Along with Promotion of Neurosphere Growth and Subsequent Neuronal Specification in Undifferentiated Neural Progenitor Cells Exposed to Theanine.

Takarada T, Ogura M, Nakamichi N, Kakuda T, Nakazato R, Kokubo H, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y.

Neurochemical Research   41 ( 1-2 )   5 - 15   2016年2月

Weight loss by ppc-1, a novel small molecule mitochondrial uncoupler derived from slime mold.

Suzuki T, Kikuchi H, Ogura M, Homma MK, Oshima Y, Homma Y.

PLoS ONE   10 ( 2 )   e0117088   2015年2月

Synthesis of prenylated quinolinecarboxylic acid derivatives and their anti-obesity activities.

Kikuchi H, Suzuki T, Ogura M, Homma MK, Homma Y, Oshima Y.

Bioorganic & Medicinal Chemistry   23 ( 1 )   66 - 72   2015年1月

Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species

Ogura M, Yamaki J, Homma MK, Homma Y.

FEBS Letters   588 ( 17 )   2837 - 2843   2014年8月

Myosin VI reduces proliferation, but not differentiation, in pluripotent P19 cells.

Takarada T, Kou M, Nakamichi N, Ogura M, Ito Y, Fukumori R, Kokubo H, Acosta GB, Hinoi E, Yoneda Y

PLoS ONE   8 ( 5 )   e63947   2013年5月

Promotion of both proliferation and differentiation in pluripotent P19 cells with stable overexpression of the glutamine transporter Slc38a1

Ogura M, Kakuda T, Takarada T, Nakamichi N, Fukumori R, Kim Y, Hinoi E, Yoneda Y

PLoS ONE   7 ( 10 )   e48270   2012年10月

Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components.

Ogura M, Yamaki J, Homma MK, Homma Y.

Biochemical Journal   447 ( 2 )   281 - 289   2012年10月

Possible neuroprotective property of nicotinic acetylcholine receptors in association with predominant upregulation of glial cell line-derived neurotrophic factor in astrocytes.

Takarada T, Nakamichi N, Kawagoe H, Ogura M, Fukumori R, Nakazato R, Fujikawa K, Kou M, Yoneda Y.

Journal of Neuroscience Research   90 ( 11 )   2074 - 2085   2012年11月

Exacerbated vulnerability to oxidative stress in astrocytic C6 glioma cells with stable overexpression of the glutamine transporter slc38a1.

Ogura M, Takarada T, Nakamichi N, Kawagoe H, Sako A, Nakazato R, Yoneda Y.

Neurochemistry International   58 ( 4 )   504 - 511   2011年1月

A protein-protein interaction of stress-responsive myosin VI endowed to inhibit neural progenitor self-replication with RNA binding protein, TLS, in murine hippocampus.

Takarada T, Tamaki K, Takumi T, Ogura M, Ito Y, Nakamichi N, Yoneda Y.

Journal of Neurochemistry   110 ( 5 )   1457 - 1468   2009年6月

Theanine, an ingredient of green tea, inhibits [3H]glutamine transport in neurons and astroglia in rat brain.

Kakuda T, Hinoi E, Abe A, Nozawa A, Ogura M, Yoneda Y.

Journal of Neuroscience Research   86 ( 8 )   1846 - 1856   2008年6月

Activator protein-1 responsive to the group II metabotropic glutamate receptor subtype in association with intracellular calcium in cultured rat cortical neurons.

Sugiyama C, Nakamichi N, Ogura M, Honda E, Maeda S, Taniura H, Yoneda Y.

Neurochemistry International   51 ( 8 )   467 - 475   2007年5月

Upregulation of the glutamine transporter through transactivation mediated by cAMP/protein kinase A signals toward exacerbation of vulnerability to oxidative stress in rat neocortical astrocytes.

Ogura M, Taniura H, Nakamichi N, Yoneda Y.

Journal of Cellular Physiology   212 ( 2 )   375 - 385   2007年8月

Functional expression of a glutamine transporter responsive to downregulation by lipopolysaccharide through reduced promoter activity in cultured rat neocortical astrocytes.

Ogura M, Nakamichi N, Takano K, Oikawa H, Kambe Y, Ohno Y, Taniura H, Yoneda Y.

Journal of Neuroscience Research   83 ( 8 )   1447 - 1460   2006年6月

Stimulation of ubiquitin-proteasome pathway through the expression of amidohydrolase for N-terminal asparagine (Ntan1) in cultured rat hippocampal neurons exposed to static magnetism.

Hirai T, Taniura H, Goto Y, Ogura M, Sng J, Yoneda Y.

Journal of Neurochemistry   96 ( 6 )   1519 - 1530   2006年3月

Oxidative metabolites are involved in polyamine-induced microglial cell death.

Takano K, Ogura M, Yoneda Y, Nakamura Y.

Neuroscience   134 ( 4 )   1123 - 1131   2005年7月

Counteraction by repetitive daily exposure to static magnetism against sustained blockade of N-methyl-D-aspartate receptor channels in cultured rat hippocampal neurons.

Hirai T, Taniura H, Goto Y, Tamaki K, Oikawa H, Kambe Y, Ogura M, Ohno Y, Takarada T, Yoneda Y.

Journal of Neuroscience Research   80 ( 4 )   491 - 500   2005年5月

Protection by exogenous pyruvate through a mechanism related to monocarboxylate transporters against cell death induced by hydrogen peroxide in cultured rat cortical neurons.

Nakamichi N, Kambe Y, Oikawa H, Ogura M, Takano K, Tamaki K, Inoue M, Hinoi E, Yoneda Y.

Journal of Neurochemistry   93 ( 1 )   84 - 93   2005年4月

An increase in intracellular free calcium ions by nicotinic acetylcholine receptors in a single cultured rat cortical astrocyte.

Oikawa H, Nakamichi N, Kambe Y, Ogura M, Yoneda Y.

Journal of Neuroscience Research   79 ( 4 )   535 - 544   2005年2月

Neuronal and glial responses to polyamines in the ischemic brain.

Takano K, Ogura M, Nakamura Y, Yoneda Y.

Current Neurovascular Research   2 ( 3 )   213 - 223   2005年7月

Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2

第90回日本薬理学会年会  

Phosphorylation of respiratory chain components by mitochondrial c-Src is required for neuronal viability

Neuroscience2016  

ミトコンドリア内c-Srcによる活性酸素種産生制御機構の解明

第65回日本薬理学会北部会  

Phosphorylation of respiratory complex I and II by c-Src is required for neuronal viability

第86回日本薬理学会年会  

活性酸素種産生を制御する新規コハク酸脱水素酵素相互作用タンパク質の同定と機能解析

第85回日本生化学会大会  

Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components

The 11th Biennial Meeting of the Asian-Pacific Society for Neurochemistry / 55th Annual Meeting of the Japanese Society for Neurochemistry  

呼吸機能におけるミトコンドリア内c-Srcの役割

第５４回日本神経化学会大会  

ミトコンドリアc-Srcキナーゼ活性を制御する新規相互作用タンパク質の同定と機能解析

第８４回日本生化学会大会  

ミトコンドリアc-Srcによる細胞死制御メカニズム

日本生化学会東北支部第77回例会・シンポジウム  

Regulatory mechanism of oxidative phosphorylation by mitochondrial c-Src

Keystone Symposia  

Regulation of oxidative phosphorylation by mitochondrial c-Src

第33回日本分子生物学会年会・第83回日本生化学会大会　合同大会  

活性酸素に起因する体液性免疫不全マウスの分子機序解析と新規疾患分子の同定

2014年5月 - 2015年3月

ミトコンドリア機能を標的とする粘菌由来新規天然物の作用機序解析と創薬応用

2013年8月 - 2014年3月

小椋　正人、本間　好

活性酸素を起因とする神経変性モデルマウスの構築と新規疾患分子の同定

2013年5月 - 2014年3月

ミトコンドリア内c-Src活性制御に関わる新規相互作用タンパク質の同定と機能解析

2011年4月 - 2013年3月